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The map label for this gene is murI

Identifier: 85060131

GI number: 85060131

Start: 3752666

End: 3753538

Strand: Reverse

Name: murI

Synonym: SG2153

Alternate gene names: 85060131

Gene position: 3753538-3752666 (Counterclockwise)

Preceding gene: 85060133

Following gene: 85060130

Centisome position: 89.99

GC content: 57.16

Gene sequence:

>873_bases
ATGGCTACCAGACTGCAGGATGGGAATTCTATCTCACCGGAACCTATGCTTTCTGACGGCAGCGCCGCCAAACGGCCCAC
CATTCTTGTCTTTGACTCTGGCGTGGGGGGCCTATCAATATATAATGAAGTCAGGCAAACGTTGCCCAATGCCCATTATT
TGTACGTTTTTGACAATGAGGCCTTCCCGTATGGGGAAAAACCGGAGCAATTCATTGTCGATAGGGTCGTCGCCATTGTT
GGTGCGATGTGGCGACAGCATAAGATCGACTTGGTCATCGTTGCCTGCAATACCGCCAGCACTATTTCACTGCCGGCGCT
GCGCGAGCGTTTCCCCTGTCCGATTATCGGCGTGGTACCGGCGATCAAACCGGCGGCCCGACTCACCCGCAATGGTATCG
TCGGGTTGCTGGCGACGCGCGCTACAGTACAACGCAGTTACACCCATGATCTCATCAGTCAATACGCCGGCGATTGCCAA
ATTTTGCAGTTAGGGACGGCCGAACTGGTGGATATGGCGGAAGCCAGATTGCATGGCGAATTGGTGCCCCTGCCGGTGTT
GCGCAAACTTCTGCGCCCCTGGCTAAGGGCAGCGGAGCCGCCTGACACGGTCGTACTGGGCTGTACCCACTTCCCCTTGC
TGAGCCAGGAACTCCAGGCGGTACTACCGGAAGGAACCCGTCTGGTCGATTCCGGGTCGGCCATTGCCCGCCGCGCGGCT
TGGCTGGTGGAGCATGACATGGACGTCAGCAGTCTGCAGGGCGAAACAGGACCGAATAAAACTTATTGCCTCGTTACCAC
GCCACAGGCGGTAGCGCTGATGCCGGCACTGACGCGCTATGGTTTCGGCTCATCGGGAATGCTTACGCTTTAA

Upstream 100 bases:

>100_bases
ATCAGTCTGTGGGATATTGCGGCGTCATATCCGCTGACAACCCGGTTGACGGTTCGTGGTAGACTGGCCAATGTGTTCGA
TAAAAATTATGAGACAGCTT

Downstream 100 bases:

>100_bases
CAGCACCCGATGCGGCCTCTCGGCGCGCGTTATTGCCCGTCCTTTCGCGAGTCGGATGTCAGCCGCCCCAGGGATAGCAC
AAGTGGCGGAAAGATTATGG

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MATRLQDGNSISPEPMLSDGSAAKRPTILVFDSGVGGLSIYNEVRQTLPNAHYLYVFDNEAFPYGEKPEQFIVDRVVAIV
GAMWRQHKIDLVIVACNTASTISLPALRERFPCPIIGVVPAIKPAARLTRNGIVGLLATRATVQRSYTHDLISQYAGDCQ
ILQLGTAELVDMAEARLHGELVPLPVLRKLLRPWLRAAEPPDTVVLGCTHFPLLSQELQAVLPEGTRLVDSGSAIARRAA
WLVEHDMDVSSLQGETGPNKTYCLVTTPQAVALMPALTRYGFGSSGMLTL

Sequences:

>Translated_290_residues
MATRLQDGNSISPEPMLSDGSAAKRPTILVFDSGVGGLSIYNEVRQTLPNAHYLYVFDNEAFPYGEKPEQFIVDRVVAIV
GAMWRQHKIDLVIVACNTASTISLPALRERFPCPIIGVVPAIKPAARLTRNGIVGLLATRATVQRSYTHDLISQYAGDCQ
ILQLGTAELVDMAEARLHGELVPLPVLRKLLRPWLRAAEPPDTVVLGCTHFPLLSQELQAVLPEGTRLVDSGSAIARRAA
WLVEHDMDVSSLQGETGPNKTYCLVTTPQAVALMPALTRYGFGSSGMLTL
>Mature_289_residues
ATRLQDGNSISPEPMLSDGSAAKRPTILVFDSGVGGLSIYNEVRQTLPNAHYLYVFDNEAFPYGEKPEQFIVDRVVAIVG
AMWRQHKIDLVIVACNTASTISLPALRERFPCPIIGVVPAIKPAARLTRNGIVGLLATRATVQRSYTHDLISQYAGDCQI
LQLGTAELVDMAEARLHGELVPLPVLRKLLRPWLRAAEPPDTVVLGCTHFPLLSQELQAVLPEGTRLVDSGSAIARRAAW
LVEHDMDVSSLQGETGPNKTYCLVTTPQAVALMPALTRYGFGSSGMLTL

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=283, Percent_Identity=64.3109540636042, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_SODGM (Q2NQZ7)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455833.1
- ProteinModelPortal:   Q2NQZ7
- SMR:   Q2NQZ7
- STRING:   Q2NQZ7
- GeneID:   3868262
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2153
- NMPDR:   fig|343509.6.peg.4751
- eggNOG:   COG0796
- HOGENOM:   HBG645102
- OMA:   ARTNAMI
- PhylomeDB:   Q2NQZ7
- ProtClustDB:   PRK00865
- BioCyc:   SGLO343509:SG2153-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 31496; Mature: 31365

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRLQDGNSISPEPMLSDGSAAKRPTILVFDSGVGGLSIYNEVRQTLPNAHYLYVFDNE
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCC
AFPYGEKPEQFIVDRVVAIVGAMWRQHKIDLVIVACNTASTISLPALRERFPCPIIGVVP
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECHHHHHHCCCCEEECCC
AIKPAARLTRNGIVGLLATRATVQRSYTHDLISQYAGDCQILQLGTAELVDMAEARLHGE
CCCHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCC
LVPLPVLRKLLRPWLRAAEPPDTVVLGCTHFPLLSQELQAVLPEGTRLVDSGSAIARRAA
CCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHH
WLVEHDMDVSSLQGETGPNKTYCLVTTPQAVALMPALTRYGFGSSGMLTL
HHHHCCCCHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEC
>Mature Secondary Structure 
ATRLQDGNSISPEPMLSDGSAAKRPTILVFDSGVGGLSIYNEVRQTLPNAHYLYVFDNE
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCC
AFPYGEKPEQFIVDRVVAIVGAMWRQHKIDLVIVACNTASTISLPALRERFPCPIIGVVP
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECHHHHHHCCCCEEECCC
AIKPAARLTRNGIVGLLATRATVQRSYTHDLISQYAGDCQILQLGTAELVDMAEARLHGE
CCCHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCC
LVPLPVLRKLLRPWLRAAEPPDTVVLGCTHFPLLSQELQAVLPEGTRLVDSGSAIARRAA
CCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHH
WLVEHDMDVSSLQGETGPNKTYCLVTTPQAVALMPALTRYGFGSSGMLTL
HHHHCCCCHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA