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The map label for this gene is zur [H]

Identifier: 85060117

GI number: 85060117

Start: 3714099

End: 3714608

Strand: Reverse

Name: zur [H]

Synonym: SG2139

Alternate gene names: 85060117

Gene position: 3714608-3714099 (Counterclockwise)

Preceding gene: 85060119

Following gene: 85060116

Centisome position: 89.05

GC content: 51.37

Gene sequence:

>510_bases
ATGAAAACAACGACTGAAAACCCTCTTCTCAGCCAGGCCGAAGAATTGTGCGAGCAGCGCAATGTCCGTCTGACGCCGCA
ACGGCTGGAAGTCCTGCGGCTGATGTCTCAACAAAATGGTGCGATAAGTGCTTATGATTTGCTGGATTTATTGCGTCAAT
CTGAACCGCAGGCAAAACCCCCGACCGTTTACCGTGCGCTGGATTTTTTACTTGAGCAAGGTTTTGTTCATCGCGTCGAG
TCCACCAACAGCTTTGTACTGTGCCATCATTTCGCGGAACCATCCCATGCTTCCGCTTTCTTTATCTGCGACCGCTGTGG
TCAGGTGACAGAGCAGACCACGCAGGGGATAGACGAAATTTTACAGCGTATGGCGGCGGCGGCCGGTTTTACTCTCTCCT
ATAACGTGGTAGAGGCGCATGGCTTTTGTCCACAATGTAGTGAGGTGCAGGCATGTCAACATCCTGACGCCTGTGAACAT
GACCACAGCGTGGCAATAAAAAAACGCTAG

Upstream 100 bases:

>100_bases
AGCCCTTTATGCCCGTCTATACAGCGCTTGAGCGAGCTTTAGTCGTGGTTTTTGTGTCTTCGTGGTAATATAGATTGAGA
AACCGCAACCGGGGAGCATC

Downstream 100 bases:

>100_bases
CATCCTCTTGCCGAATTTCTCTTTCCTGTAAAACAGCATGGCTATCCGGGCCATTAGGCTGCTCAATAGCCCGCAAAATG
ACACAAACTTGTTGCGCATG

Product: zinc uptake transcriptional repressor

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MKTTTENPLLSQAEELCEQRNVRLTPQRLEVLRLMSQQNGAISAYDLLDLLRQSEPQAKPPTVYRALDFLLEQGFVHRVE
STNSFVLCHHFAEPSHASAFFICDRCGQVTEQTTQGIDEILQRMAAAAGFTLSYNVVEAHGFCPQCSEVQACQHPDACEH
DHSVAIKKR

Sequences:

>Translated_169_residues
MKTTTENPLLSQAEELCEQRNVRLTPQRLEVLRLMSQQNGAISAYDLLDLLRQSEPQAKPPTVYRALDFLLEQGFVHRVE
STNSFVLCHHFAEPSHASAFFICDRCGQVTEQTTQGIDEILQRMAAAAGFTLSYNVVEAHGFCPQCSEVQACQHPDACEH
DHSVAIKKR
>Mature_169_residues
MKTTTENPLLSQAEELCEQRNVRLTPQRLEVLRLMSQQNGAISAYDLLDLLRQSEPQAKPPTVYRALDFLLEQGFVHRVE
STNSFVLCHHFAEPSHASAFFICDRCGQVTEQTTQGIDEILQRMAAAAGFTLSYNVVEAHGFCPQCSEVQACQHPDACEH
DHSVAIKKR

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=169, Percent_Identity=69.2307692307692, Blast_Score=259, Evalue=9e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18987; Mature: 18987

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTTENPLLSQAEELCEQRNVRLTPQRLEVLRLMSQQNGAISAYDLLDLLRQSEPQAKP
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
PTVYRALDFLLEQGFVHRVESTNSFVLCHHFAEPSHASAFFICDRCGQVTEQTTQGIDEI
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
LQRMAAAAGFTLSYNVVEAHGFCPQCSEVQACQHPDACEHDHSVAIKKR
HHHHHHHCCCEEEEEEHCCCCCCCCCCHHHHCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MKTTTENPLLSQAEELCEQRNVRLTPQRLEVLRLMSQQNGAISAYDLLDLLRQSEPQAKP
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
PTVYRALDFLLEQGFVHRVESTNSFVLCHHFAEPSHASAFFICDRCGQVTEQTTQGIDEI
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
LQRMAAAAGFTLSYNVVEAHGFCPQCSEVQACQHPDACEHDHSVAIKKR
HHHHHHHCCCEEEEEEHCCCCCCCCCCHHHHCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]