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The map label for this gene is cocE [H]

Identifier: 85060028

GI number: 85060028

Start: 3536209

End: 3536892

Strand: Reverse

Name: cocE [H]

Synonym: SG2050

Alternate gene names: 85060028

Gene position: 3536892-3536209 (Counterclockwise)

Preceding gene: 85060029

Following gene: 85060027

Centisome position: 84.79

GC content: 56.58

Gene sequence:

>684_bases
GTGCCGACCATCGGCGGCTCCTTAACCAGCGGCGAGCCTATTTTCACCGGCGGTGCGTTTGATCAGCGTGAAGATGCGCG
CTTCTTAGGCTGCCGCCATCCCGGACTACCGCTTACCACTCGTCAGGATGTGTTGTCGTTCGAGACGCCGCCGCTTGCGC
AGGATTTGGCGGTGATAGGCGAGGTATTCATCGAGTTGGTGGTGTCGACGGATGCGCCGGATACTGATTTCACCGCCAAG
CTGATAGATGTCTACCCTCCCAGTGACGATTACCTGACCGGTTTTGCCATGAACATTACCGACGGCATTTTCCGCTGCCG
CTATCGCAACGGTTTTAATAATCCGCAGCTTGTTACATCCGAGGAACCCTTTACTCTGCGTATCGAGCCCTTCGCCACCG
CGAACCTGTTTAAAGCGGGCCACCGCATTCGCCTGGATATTTCCTCTAGCAATTTCCCGAAATACGATGTCAATCCCAAC
AGCGGTGAACCGGAGAGAAGCGGACGCTGTCCGCGCAGCGCACTCAATACGGTACATTTAGCGCCGCAATTTCGCAGCCG
TATGCTGCAGCAAACCCTGCCGTTTGCTGCGTTTAGCGTCGGTGGCGGCAGCCGTTGTCGGAATGAGGCGCTCATCGTCG
GTTGCGATAACTGCAACCGGTTGCGGCGCCTGTTAACGATCTAA

Upstream 100 bases:

>100_bases
CTGAACCATTAATGCTTTATCTGCAAGACGACATGAGCCTGTCTTCGCAGTCGCTTGCTGAACCTCCCGACTTAGCTACC
GGTTTGATCCGACCCGGCTG

Downstream 100 bases:

>100_bases
GGGGCATGCCATCTACGCCCGCGATCCTCTCCATTTCCAGGCAGCGCCACCTATCAGCTGACAAGTCCACCGTTTGCCAC
CGGCGTTTTGCCGCATTCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MPTIGGSLTSGEPIFTGGAFDQREDARFLGCRHPGLPLTTRQDVLSFETPPLAQDLAVIGEVFIELVVSTDAPDTDFTAK
LIDVYPPSDDYLTGFAMNITDGIFRCRYRNGFNNPQLVTSEEPFTLRIEPFATANLFKAGHRIRLDISSSNFPKYDVNPN
SGEPERSGRCPRSALNTVHLAPQFRSRMLQQTLPFAAFSVGGGSRCRNEALIVGCDNCNRLRRLLTI

Sequences:

>Translated_227_residues
MPTIGGSLTSGEPIFTGGAFDQREDARFLGCRHPGLPLTTRQDVLSFETPPLAQDLAVIGEVFIELVVSTDAPDTDFTAK
LIDVYPPSDDYLTGFAMNITDGIFRCRYRNGFNNPQLVTSEEPFTLRIEPFATANLFKAGHRIRLDISSSNFPKYDVNPN
SGEPERSGRCPRSALNTVHLAPQFRSRMLQQTLPFAAFSVGGGSRCRNEALIVGCDNCNRLRRLLTI
>Mature_226_residues
PTIGGSLTSGEPIFTGGAFDQREDARFLGCRHPGLPLTTRQDVLSFETPPLAQDLAVIGEVFIELVVSTDAPDTDFTAKL
IDVYPPSDDYLTGFAMNITDGIFRCRYRNGFNNPQLVTSEEPFTLRIEPFATANLFKAGHRIRLDISSSNFPKYDVNPNS
GEPERSGRCPRSALNTVHLAPQFRSRMLQQTLPFAAFSVGGGSRCRNEALIVGCDNCNRLRRLLTI

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 25060; Mature: 24928

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTIGGSLTSGEPIFTGGAFDQREDARFLGCRHPGLPLTTRQDVLSFETPPLAQDLAVIG
CCCCCCCCCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHH
EVFIELVVSTDAPDTDFTAKLIDVYPPSDDYLTGFAMNITDGIFRCRYRNGFNNPQLVTS
HHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEHHHHHEEEEECCCCCCCEEEEC
EEPFTLRIEPFATANLFKAGHRIRLDISSSNFPKYDVNPNSGEPERSGRCPRSALNTVHL
CCCEEEEECCCCHHHHHHCCCEEEEEECCCCCCEECCCCCCCCCCCCCCCCHHHHHEEEE
APQFRSRMLQQTLPFAAFSVGGGSRCRNEALIVGCDNCNRLRRLLTI
CHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHCC
>Mature Secondary Structure 
PTIGGSLTSGEPIFTGGAFDQREDARFLGCRHPGLPLTTRQDVLSFETPPLAQDLAVIG
CCCCCCCCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHH
EVFIELVVSTDAPDTDFTAKLIDVYPPSDDYLTGFAMNITDGIFRCRYRNGFNNPQLVTS
HHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEHHHHHEEEEECCCCCCCEEEEC
EEPFTLRIEPFATANLFKAGHRIRLDISSSNFPKYDVNPNSGEPERSGRCPRSALNTVHL
CCCEEEEECCCCHHHHHHCCCEEEEEECCCCCCEECCCCCCCCCCCCCCCCHHHHHEEEE
APQFRSRMLQQTLPFAAFSVGGGSRCRNEALIVGCDNCNRLRRLLTI
CHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]