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The map label for this gene is mngR [H]

Identifier: 85060018

GI number: 85060018

Start: 3514602

End: 3515468

Strand: Reverse

Name: mngR [H]

Synonym: SG2040

Alternate gene names: 85060018

Gene position: 3515468-3514602 (Counterclockwise)

Preceding gene: 85060021

Following gene: 85060012

Centisome position: 84.28

GC content: 45.79

Gene sequence:

>867_bases
ATGAACCGTAAATCTGTTAAATGGATCACATTTATCACGCGCATCGCGCCGGTAGGTGAACTCTTTTTCCTTTGTCCCCA
CACGGGACTGGGGTATGAACAAACTGATAACGCGGTGGAAAACAACGAGATGACCGACAATATTACGGAAAAGCAAAAAG
AGGTTATCGACTATATCCTCGGGAAAATTAAAGAAAAAGAACGTCAGTCTGGCGATAAACTAGATACGGAAATTGCGATT
GCCAAGGCGCTGAATATCACCCGCTCAACGGTCCGGGAAGCGACCCGTATTCTTATCGATCAACGCCGCATCTACCGGAT
AAAGGGCTCCGGTATTTTTATTGGCTCTATTGGCAAGAATAATCAGTCGGGACGGTTCCATGCGCTGTCCCCTTTTGACT
ATCAGGCCCAGAAAGGGGGGCATCGCGCCGGCCGTAAAGTCATTTCCGCCAGTATCGTAACCGTTCCTGATGCGGCGATG
GCGCAGGCTTTACGAATAAAAAACAGCGATCAGGTGTATAAAATCTTGCGCCTGATGAGCTTCGACGATGTTCCTATTTC
CCTTGAATATATCCACTTCCCTGTTTCGTTATTTAAATCGATAGAATTTAAAGAGCTGGAGAATTCCAAATATTCTTATA
TTGAGCGCATAACCGGTAAAAAGGTCTACAAACGCGATCAGAATTTCCATGCGTTCAACGCCACCGATGCTGAAATGATG
AAGTATATGAATATCGCTGAAAATGCGGCCATGATGGAGCTTTATGAAGTGGTTTATCTCGACGATGGCACCCCGTTTGA
AGTGAATATCGCTATTGTAAACACCAATATGCTGCACCTGAGCCAGGTATCCGTCCGCGGTGAATGA

Upstream 100 bases:

>100_bases
TGGTAGTGGTACATATTAAATTTATATAGTTATCTTAAGAATGCACCTAGACATGACTATACACAAGAGGTAGGATTAGA
AAGATGAGCAGACAGCAGGG

Downstream 100 bases:

>100_bases
TGATGGCCAGTTAGGACGCCCGTAAATCAACCCCCCTCCGACAATGAAAAGCCGGGATGGCGCTGAGTTCCCGTATTTCT
GTTACGTGCTTGGTCGCGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Fatty acyl-responsive regulator; Protein P30 [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNRKSVKWITFITRIAPVGELFFLCPHTGLGYEQTDNAVENNEMTDNITEKQKEVIDYILGKIKEKERQSGDKLDTEIAI
AKALNITRSTVREATRILIDQRRIYRIKGSGIFIGSIGKNNQSGRFHALSPFDYQAQKGGHRAGRKVISASIVTVPDAAM
AQALRIKNSDQVYKILRLMSFDDVPISLEYIHFPVSLFKSIEFKELENSKYSYIERITGKKVYKRDQNFHAFNATDAEMM
KYMNIAENAAMMELYEVVYLDDGTPFEVNIAIVNTNMLHLSQVSVRGE

Sequences:

>Translated_288_residues
MNRKSVKWITFITRIAPVGELFFLCPHTGLGYEQTDNAVENNEMTDNITEKQKEVIDYILGKIKEKERQSGDKLDTEIAI
AKALNITRSTVREATRILIDQRRIYRIKGSGIFIGSIGKNNQSGRFHALSPFDYQAQKGGHRAGRKVISASIVTVPDAAM
AQALRIKNSDQVYKILRLMSFDDVPISLEYIHFPVSLFKSIEFKELENSKYSYIERITGKKVYKRDQNFHAFNATDAEMM
KYMNIAENAAMMELYEVVYLDDGTPFEVNIAIVNTNMLHLSQVSVRGE
>Mature_288_residues
MNRKSVKWITFITRIAPVGELFFLCPHTGLGYEQTDNAVENNEMTDNITEKQKEVIDYILGKIKEKERQSGDKLDTEIAI
AKALNITRSTVREATRILIDQRRIYRIKGSGIFIGSIGKNNQSGRFHALSPFDYQAQKGGHRAGRKVISASIVTVPDAAM
AQALRIKNSDQVYKILRLMSFDDVPISLEYIHFPVSLFKSIEFKELENSKYSYIERITGKKVYKRDQNFHAFNATDAEMM
KYMNIAENAAMMELYEVVYLDDGTPFEVNIAIVNTNMLHLSQVSVRGE

Specific function: Represses mngA and mngB. Regulates its own expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=224, Percent_Identity=27.6785714285714, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790118, Length=192, Percent_Identity=25, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 32848; Mature: 32848

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKSVKWITFITRIAPVGELFFLCPHTGLGYEQTDNAVENNEMTDNITEKQKEVIDYIL
CCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GKIKEKERQSGDKLDTEIAIAKALNITRSTVREATRILIDQRRIYRIKGSGIFIGSIGKN
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCC
NQSGRFHALSPFDYQAQKGGHRAGRKVISASIVTVPDAAMAQALRIKNSDQVYKILRLMS
CCCCEEEEECCCCCHHHCCCHHHHHHHHHEEEEECCCHHHHHHHHCCCCHHHHHHHHHHC
FDDVPISLEYIHFPVSLFKSIEFKELENSKYSYIERITGKKVYKRDQNFHAFNATDAEMM
CCCCCEEEEEEEHHHHHHHCCCHHHHCCCHHHHHHHHHCHHHHHCCCCCEEECCCHHHHH
KYMNIAENAAMMELYEVVYLDDGTPFEVNIAIVNTNMLHLSQVSVRGE
HHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCEEEEEEEEECCC
>Mature Secondary Structure
MNRKSVKWITFITRIAPVGELFFLCPHTGLGYEQTDNAVENNEMTDNITEKQKEVIDYIL
CCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GKIKEKERQSGDKLDTEIAIAKALNITRSTVREATRILIDQRRIYRIKGSGIFIGSIGKN
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCC
NQSGRFHALSPFDYQAQKGGHRAGRKVISASIVTVPDAAMAQALRIKNSDQVYKILRLMS
CCCCEEEEECCCCCHHHCCCHHHHHHHHHEEEEECCCHHHHHHHHCCCCHHHHHHHHHHC
FDDVPISLEYIHFPVSLFKSIEFKELENSKYSYIERITGKKVYKRDQNFHAFNATDAEMM
CCCCCEEEEEEEHHHHHHHCCCHHHHCCCHHHHHHHHHCHHHHHCCCCCEEECCCHHHHH
KYMNIAENAAMMELYEVVYLDDGTPFEVNIAIVNTNMLHLSQVSVRGE
HHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548486; 9278503; 9063979; 8905232; 7805834 [H]