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The map label for this gene is xerD

Identifier: 85059971

GI number: 85059971

Start: 3449547

End: 3450446

Strand: Reverse

Name: xerD

Synonym: SG1993

Alternate gene names: 85059971

Gene position: 3450446-3449547 (Counterclockwise)

Preceding gene: 85059973

Following gene: 85059970

Centisome position: 82.72

GC content: 58.67

Gene sequence:

>900_bases
ATGGAACGACCGGATGACGTCATTATTGAGCAGTTTCTTGATTCCCTGTGGCTGGAACGCAACCTGGCGGAAAACACCCT
GGCCTCCTATCGCCTTGACCTGCAGGCGCTCTCGGCCTGGCTGCAGTCCCAGCAGCGCGACAGTCTGAATGCGAGCTCGG
CCGATTTGCAGGCCTTTCTGGCCGATCGTCTCGATCACGGCTACAAGGCCACCAGTTCCGCCAGGCTGCTCAGCGCCACG
CGCCGTTTTTTTCAGTATCTGTACCGGGAAAAACGGCGCGGCAACGATCCCAGCGCCGGCATCTCGGCGCCCAAATTACC
GCAGCGTCTGCCTAAAGATCTCAGCGAGGCCCAGGTGGGTGATTTGCTGGCGGCGCCTGCTATCGCCGATCCCGTCGAAC
TACGCGATAAGGCGATGCTGGAGGTGCTCTACGCCACCGGTTTGCGGGTGTCCGAGCTGGTTGGATTGACCCTGTCGGAC
GTCAGCCTGCGGCAGGGTGTAGTGCGGGTGATTGGTAAAGGGGATAAGGAGCGGCTGGTGCCATTGGGGGAAGAGGCGGT
ATACTGGATTGAGTATTATCTGGAACATGGCCGTCCTGCGCTGACCCATGGCCAAAGCCTGGACATTCTGTTTCCCAGTA
ACCGCAGCCGCAAGATGACCCGCCAGACGTTCTGGCATCGCATTAAACATTATGCCATTCTGGCGGGCATTGACAGCGAG
CGGCTCTCCCCCCATGTTTTGCGGCATGCCTTTGCGACCCATTTGCTGAATCACGGGGCGGATTTACGTGTGGTGCAACT
GCTGCTGGGACACAGTGATCTTTCGACGACGCAGATCTATACCCATGTCGCCACTGAACGATTGAAGCTTATCCATCAGC
AGCATCATCCCCGCGCCTGA

Upstream 100 bases:

>100_bases
TCTCATGTTACTCTTGCAAACAACCTAATGGCGTCAAGTGTACCAGATTTGACGGTATGTCAGGCATAATGTCATCTGCC
GCCCCGTACAGGAGTCAGTT

Downstream 100 bases:

>100_bases
GCGGTGGCGTTGAAACGAATTTAAGGCGTATGTATGCGCCGACCCCGACCCGGGTGTTTAAATAAGGATTAAAATGTGAA
CAAAAGCCTGGTACTGCTAT

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MERPDDVIIEQFLDSLWLERNLAENTLASYRLDLQALSAWLQSQQRDSLNASSADLQAFLADRLDHGYKATSSARLLSAT
RRFFQYLYREKRRGNDPSAGISAPKLPQRLPKDLSEAQVGDLLAAPAIADPVELRDKAMLEVLYATGLRVSELVGLTLSD
VSLRQGVVRVIGKGDKERLVPLGEEAVYWIEYYLEHGRPALTHGQSLDILFPSNRSRKMTRQTFWHRIKHYAILAGIDSE
RLSPHVLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATERLKLIHQQHHPRA

Sequences:

>Translated_299_residues
MERPDDVIIEQFLDSLWLERNLAENTLASYRLDLQALSAWLQSQQRDSLNASSADLQAFLADRLDHGYKATSSARLLSAT
RRFFQYLYREKRRGNDPSAGISAPKLPQRLPKDLSEAQVGDLLAAPAIADPVELRDKAMLEVLYATGLRVSELVGLTLSD
VSLRQGVVRVIGKGDKERLVPLGEEAVYWIEYYLEHGRPALTHGQSLDILFPSNRSRKMTRQTFWHRIKHYAILAGIDSE
RLSPHVLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATERLKLIHQQHHPRA
>Mature_299_residues
MERPDDVIIEQFLDSLWLERNLAENTLASYRLDLQALSAWLQSQQRDSLNASSADLQAFLADRLDHGYKATSSARLLSAT
RRFFQYLYREKRRGNDPSAGISAPKLPQRLPKDLSEAQVGDLLAAPAIADPVELRDKAMLEVLYATGLRVSELVGLTLSD
VSLRQGVVRVIGKGDKERLVPLGEEAVYWIEYYLEHGRPALTHGQSLDILFPSNRSRKMTRQTFWHRIKHYAILAGIDSE
RLSPHVLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATERLKLIHQQHHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerC binding sites by a short central region, forming

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=78.6941580756014, Blast_Score=466, Evalue=1e-133,
Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=39.8648648648649, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1790767, Length=170, Percent_Identity=30, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790768, Length=148, Percent_Identity=30.4054054054054, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33887; Mature: 33887

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERPDDVIIEQFLDSLWLERNLAENTLASYRLDLQALSAWLQSQQRDSLNASSADLQAFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ADRLDHGYKATSSARLLSATRRFFQYLYREKRRGNDPSAGISAPKLPQRLPKDLSEAQVG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DLLAAPAIADPVELRDKAMLEVLYATGLRVSELVGLTLSDVSLRQGVVRVIGKGDKERLV
HHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHCCC
PLGEEAVYWIEYYLEHGRPALTHGQSLDILFPSNRSRKMTRQTFWHRIKHYAILAGIDSE
CCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCHH
RLSPHVLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATERLKLIHQQHHPRA
HCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERPDDVIIEQFLDSLWLERNLAENTLASYRLDLQALSAWLQSQQRDSLNASSADLQAFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ADRLDHGYKATSSARLLSATRRFFQYLYREKRRGNDPSAGISAPKLPQRLPKDLSEAQVG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DLLAAPAIADPVELRDKAMLEVLYATGLRVSELVGLTLSDVSLRQGVVRVIGKGDKERLV
HHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHCCC
PLGEEAVYWIEYYLEHGRPALTHGQSLDILFPSNRSRKMTRQTFWHRIKHYAILAGIDSE
CCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCHH
RLSPHVLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATERLKLIHQQHHPRA
HCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]