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The map label for this gene is rppH

Identifier: 85059958

GI number: 85059958

Start: 3417603

End: 3418130

Strand: Reverse

Name: rppH

Synonym: SG1980

Alternate gene names: 85059958

Gene position: 3418130-3417603 (Counterclockwise)

Preceding gene: 85059964

Following gene: 85059957

Centisome position: 81.95

GC content: 56.06

Gene sequence:

>528_bases
GTGATCGATGATGATGGCTACCGCCCAAATGTTGGTATTGTAATCTGTAATCTCGACGGGCAGGTGCTGTGGGCCAGGCG
ATACGGACAGCATTCCTGGCAGTTCCCTCAGGGCGGTATCAACGCTGGCGAGACCGCAGAGCAGGCGATGTACCGCGAGC
TGTTCGAGGAAGTCGGCCTGAGCCGCAAAGATGTGCGCATTCTGGCTTCGACGCGAAACTGGCTGCGGTATAAGCTTCCC
AAGCGGCTCGTGCGTTGGGACACCAAGCCGGTATGTATTGGTCAGAAGCAAAAATGGTTTCTGCTACAGCTTTTATGTCC
AGATGCGGATATCAATATGCAGCGCGGGGGGATCCCTGAATTTGACGGCTGGCGCTGGGTCAGCTTCTGGTACCCGGTAC
GTCAGGTTGTTTCCTTTAAACGGGACGTTTACCGTCGGGTAATGAAGGAATTTTCCGGCGTGGTGATGCCGCTGCAGGAA
ACTGCAGCGCAGCGCTCCGCGTCGGCACACAGACGGAAAAGAGGCTAA

Upstream 100 bases:

>100_bases
GTGTTATTCACCGGTGATTAGTGAAAACCAGTGGTTTACCGTACACAGCGAGTATGAAACAATCGGAACATCTTACATTT
TATGTAATCGAGGTAGTCCG

Downstream 100 bases:

>100_bases
GTCACGCAGATTATGCTCACGCGCTTGCGGGAAATCGTTGAAAAGGTCGCAGCCGCGCCGCGTCTGTCGGACTCACTTGA
CATTCTGGTCAATGAAACCT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MIDDDGYRPNVGIVICNLDGQVLWARRYGQHSWQFPQGGINAGETAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQKWFLLQLLCPDADINMQRGGIPEFDGWRWVSFWYPVRQVVSFKRDVYRRVMKEFSGVVMPLQE
TAAQRSASAHRRKRG

Sequences:

>Translated_175_residues
MIDDDGYRPNVGIVICNLDGQVLWARRYGQHSWQFPQGGINAGETAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQKWFLLQLLCPDADINMQRGGIPEFDGWRWVSFWYPVRQVVSFKRDVYRRVMKEFSGVVMPLQE
TAAQRSASAHRRKRG
>Mature_175_residues
MIDDDGYRPNVGIVICNLDGQVLWARRYGQHSWQFPQGGINAGETAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQKWFLLQLLCPDADINMQRGGIPEFDGWRWVSFWYPVRQVVSFKRDVYRRVMKEFSGVVMPLQE
TAAQRSASAHRRKRG

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=176, Percent_Identity=85.7954545454545, Blast_Score=312, Evalue=9e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_SODGM (Q2NRH0)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455660.1
- ProteinModelPortal:   Q2NRH0
- SMR:   Q2NRH0
- STRING:   Q2NRH0
- GeneID:   3866788
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1980
- NMPDR:   fig|343509.6.peg.4273
- eggNOG:   COG0494
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- PhylomeDB:   Q2NRH0
- ProtClustDB:   PRK00714
- BioCyc:   SGLO343509:SG1980-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20577; Mature: 20577

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDDGYRPNVGIVICNLDGQVLWARRYGQHSWQFPQGGINAGETAEQAMYRELFEEVGL
CCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
SRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLLCPDADINMQRGGIPE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCC
FDGWRWVSFWYPVRQVVSFKRDVYRRVMKEFSGVVMPLQETAAQRSASAHRRKRG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDDDGYRPNVGIVICNLDGQVLWARRYGQHSWQFPQGGINAGETAEQAMYRELFEEVGL
CCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
SRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLLCPDADINMQRGGIPE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCC
FDGWRWVSFWYPVRQVVSFKRDVYRRVMKEFSGVVMPLQETAAQRSASAHRRKRG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA