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The map label for this gene is cdsA

Identifier: 85059915

GI number: 85059915

Start: 3341984

End: 3342841

Strand: Reverse

Name: cdsA

Synonym: SG1937

Alternate gene names: 85059915

Gene position: 3342841-3341984 (Counterclockwise)

Preceding gene: 85059916

Following gene: 85059914

Centisome position: 80.14

GC content: 61.07

Gene sequence:

>858_bases
TTGCTGAAGTATCGCCTGATTACTGCCTTGGTCCTGATACCCATAGTTATCGCCGCACTGTTTTTGTTGCCGTCGGTTGG
CTTTGCCCTGGTCACCCTCGCGGTGTGCATGCTCAGCGCCTGGGAATGGGGCCAGCTCGCGGGACTGGCCTCGCGCAGCC
AGCGTATCTGGCTGGCCATTCTCTGCGGCCTGCTGCTGGCGCTGATGATGCTCACCGTGCCGGCCTATCGGCCGTTCATG
ACCGTCTGGCAGGCGCAATATGCCCTGTGGGCCGCCCTGGCCTGGTGGCTGGCGGCGGCGCTGCTGGTGTTGTGCTACCC
CCGCTCCGCCACGCTGTGGCGTGAATCTCGGCCGCTGCGGCTGGCATTCGGCATCCTGACCATTTTGCCCTTCTTCTGGG
GGATGCTGGCGCTGCGTCAGCACCATTATGATATTAACCACTTCACCGGCGCCTGGTGGCTATTGTATGTCATTGTGCTG
GTGTGGGGCTCGGATTCCGGCGCTTACATGTTCGGGCGCGCGCTGGGTCGCCATAAGCTGGCGCCAAAAGTCTCTCCCGG
TAAAACCTGGGAAGGGTTGGTGGGCGGGTTGGTCACCTCCGCGGTCATCGCCTGGCTGTTTGGCAAGTATGCGCCGCTTG
ACGCCGCACCGCTTACGCTGCTGGTCTGCTCAATCGTGGCGGCACTGGCGTCGGTGTTGGGTGATTTAACCGAAAGTATG
TTCAAACGGGAGGCAGGAATCAAGGACAGCGGCCATTTAATCCCCGGCCATGGCGGCATTTTAGATCGTATAGACAGCCT
GACCGCCGCAGTGCCGGTGTTCGCCTGTCTGATGCTGCTGGTCTTTAACGCTATCTGA

Upstream 100 bases:

>100_bases
CGACGCTGTTTTTGAAGGTGCGCTGGATGCTTTTGCTCAACGCGAGCGGCGCTTCGGTGGAACAACACCTAATGATGCCA
ACGCATCCTAAGGGGGATTT

Downstream 100 bases:

>100_bases
GTCGGGACTGGGAGCGCTTATGCTGCACTTTTTCTGGATTCTTGCCGCGTTTATCGTGGCGCTGGGCGTTTTGATAACGG
TGCACGAGTTCGGCCATTTT

Product: CDP-diglyceride synthase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLKYRLITALVLIPIVIAALFLLPSVGFALVTLAVCMLSAWEWGQLAGLASRSQRIWLAILCGLLLALMMLTVPAYRPFM
TVWQAQYALWAALAWWLAAALLVLCYPRSATLWRESRPLRLAFGILTILPFFWGMLALRQHHYDINHFTGAWWLLYVIVL
VWGSDSGAYMFGRALGRHKLAPKVSPGKTWEGLVGGLVTSAVIAWLFGKYAPLDAAPLTLLVCSIVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLMLLVFNAI

Sequences:

>Translated_285_residues
MLKYRLITALVLIPIVIAALFLLPSVGFALVTLAVCMLSAWEWGQLAGLASRSQRIWLAILCGLLLALMMLTVPAYRPFM
TVWQAQYALWAALAWWLAAALLVLCYPRSATLWRESRPLRLAFGILTILPFFWGMLALRQHHYDINHFTGAWWLLYVIVL
VWGSDSGAYMFGRALGRHKLAPKVSPGKTWEGLVGGLVTSAVIAWLFGKYAPLDAAPLTLLVCSIVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLMLLVFNAI
>Mature_285_residues
MLKYRLITALVLIPIVIAALFLLPSVGFALVTLAVCMLSAWEWGQLAGLASRSQRIWLAILCGLLLALMMLTVPAYRPFM
TVWQAQYALWAALAWWLAAALLVLCYPRSATLWRESRPLRLAFGILTILPFFWGMLALRQHHYDINHFTGAWWLLYVIVL
VWGSDSGAYMFGRALGRHKLAPKVSPGKTWEGLVGGLVTSAVIAWLFGKYAPLDAAPLTLLVCSIVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLMLLVFNAI

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=285, Percent_Identity=73.3333333333333, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1787677, Length=112, Percent_Identity=45.5357142857143, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31276; Mature: 31276

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]