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The map label for this gene is rseP [H]

Identifier: 85059914

GI number: 85059914

Start: 3340609

End: 3341964

Strand: Reverse

Name: rseP [H]

Synonym: SG1936

Alternate gene names: 85059914

Gene position: 3341964-3340609 (Counterclockwise)

Preceding gene: 85059915

Following gene: 85059913

Centisome position: 80.12

GC content: 57.01

Gene sequence:

>1356_bases
ATGCTGCACTTTTTCTGGATTCTTGCCGCGTTTATCGTGGCGCTGGGCGTTTTGATAACGGTGCACGAGTTCGGCCATTT
TTGGGTGGCCCGCCGCTGCGGCGTGACGGTGGAACGTTTTTCCATCGGTTTCGGGCGCGCGCTGTGGCGTCGGCGCGATA
AACGCGGCACGGAATATGTTATCGCCGCCATTCCCCTGGGTGGCTATGTCAAAATGCTGGATGAGCGGGTAGACACCGTC
GCGCCCGAACGTCGTCATGAAGCGTTCAACCACAAAACCGTCTGGCAACGTGCCGCGATCATCGCCGCCGGACCGGTATT
TAACTTCCTTTTCGCTATCTTTGCCTACTGGCTGGTGTTTCTTATCGGCGTGCCGAGCTATCGGCCGGTGATCGGCGAAG
TGGCCCCTCATTCTATCGCGGCCCAGGCCGAAATTTCTCCCGGCATGGAACTTAAGTCGGTTGACGGTATCGAAACGCCT
GATTGGGATTCGGTTCGTCTGCAGCTCATCGACAAGATTGGCGACGGTGAAACCACCCTCGGCGTCGCCTCGTTCGGCTC
CCAAAGCGCCGAGCGGAAAACGTTGGATTTGTGCGACTGGCAGTTTGAGCCGAACAGGCAGGATGCGATCGTGGCGCTGG
GTATTATTCGATTGGGTCCGCGCATCGAGCCGGTGCTTGCCGAAGTCCAACCGGGCTCGGCGGCGATGAAAGCCGGTTTG
CAAGCCGGCGATAGGATCGTTAAAGTCGATGGTCAGCCAGTCACCGCATGGCAGTTGTTTGTGACCCGCGTACGCGACAA
TCCCGGTCGGCCACTTCAGGTGGGCATTGATCGACACGGCGAGGCCAGGGATATCACCCTGCAACCCGACAGTAAACCGG
TGGGCAAGGGGGAAGTAGAGGGGTTCGCGGGTGTTGTGCCGAAGATTATCCCGCTGCCGGCGGAGTACAAAATCGTTCGG
CAGTACGGTCCGCTACCGGCCCTGGCCCGGGCCAGCGAAAAAACCTGGCAGCTGATGCGGCTTACGGTCAGTATGTTAGG
TAAATTGATAACCGGGGATGTTAAGCTGAACAATCTTAGCGGGCCGATTTCCATCGCCCAGGGCGCAGGGATGTCAGCGG
AATACGGTTTGATTTACTACCTGATGTTTCTGGCGCTGATAAGCGTCAATTTGGGGATTATCAATCTGTTCCCGTTACCG
GTGTTAGATGGTGGCCATTTGCTCTTCCTGGCGATAGAAAAGCTCAAGGGAGGGCCGGTGTCCGAACGAGTGCAGGACTT
TAGTTACCGTATCGGCTCGATTTTGCTGGTGCTGCTAATGGGTCTGGCCCTTTTCAATGATTTCTCCAGGCTATGA

Upstream 100 bases:

>100_bases
ATTTTAGATCGTATAGACAGCCTGACCGCCGCAGTGCCGGTGTTCGCCTGTCTGATGCTGCTGGTCTTTAACGCTATCTG
AGTCGGGACTGGGAGCGCTT

Downstream 100 bases:

>100_bases
TAGCCTGAGATTATGTTAGGAAGAACGCATAACCACGATGGCGATGAAAAAGTTGCTCATAGCGTCGCTGCTTCTTAGCA
GCGCCACCGTATACGGTGCA

Product: zinc metallopeptidase RseP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MLHFFWILAAFIVALGVLITVHEFGHFWVARRCGVTVERFSIGFGRALWRRRDKRGTEYVIAAIPLGGYVKMLDERVDTV
APERRHEAFNHKTVWQRAAIIAAGPVFNFLFAIFAYWLVFLIGVPSYRPVIGEVAPHSIAAQAEISPGMELKSVDGIETP
DWDSVRLQLIDKIGDGETTLGVASFGSQSAERKTLDLCDWQFEPNRQDAIVALGIIRLGPRIEPVLAEVQPGSAAMKAGL
QAGDRIVKVDGQPVTAWQLFVTRVRDNPGRPLQVGIDRHGEARDITLQPDSKPVGKGEVEGFAGVVPKIIPLPAEYKIVR
QYGPLPALARASEKTWQLMRLTVSMLGKLITGDVKLNNLSGPISIAQGAGMSAEYGLIYYLMFLALISVNLGIINLFPLP
VLDGGHLLFLAIEKLKGGPVSERVQDFSYRIGSILLVLLMGLALFNDFSRL

Sequences:

>Translated_451_residues
MLHFFWILAAFIVALGVLITVHEFGHFWVARRCGVTVERFSIGFGRALWRRRDKRGTEYVIAAIPLGGYVKMLDERVDTV
APERRHEAFNHKTVWQRAAIIAAGPVFNFLFAIFAYWLVFLIGVPSYRPVIGEVAPHSIAAQAEISPGMELKSVDGIETP
DWDSVRLQLIDKIGDGETTLGVASFGSQSAERKTLDLCDWQFEPNRQDAIVALGIIRLGPRIEPVLAEVQPGSAAMKAGL
QAGDRIVKVDGQPVTAWQLFVTRVRDNPGRPLQVGIDRHGEARDITLQPDSKPVGKGEVEGFAGVVPKIIPLPAEYKIVR
QYGPLPALARASEKTWQLMRLTVSMLGKLITGDVKLNNLSGPISIAQGAGMSAEYGLIYYLMFLALISVNLGIINLFPLP
VLDGGHLLFLAIEKLKGGPVSERVQDFSYRIGSILLVLLMGLALFNDFSRL
>Mature_451_residues
MLHFFWILAAFIVALGVLITVHEFGHFWVARRCGVTVERFSIGFGRALWRRRDKRGTEYVIAAIPLGGYVKMLDERVDTV
APERRHEAFNHKTVWQRAAIIAAGPVFNFLFAIFAYWLVFLIGVPSYRPVIGEVAPHSIAAQAEISPGMELKSVDGIETP
DWDSVRLQLIDKIGDGETTLGVASFGSQSAERKTLDLCDWQFEPNRQDAIVALGIIRLGPRIEPVLAEVQPGSAAMKAGL
QAGDRIVKVDGQPVTAWQLFVTRVRDNPGRPLQVGIDRHGEARDITLQPDSKPVGKGEVEGFAGVVPKIIPLPAEYKIVR
QYGPLPALARASEKTWQLMRLTVSMLGKLITGDVKLNNLSGPISIAQGAGMSAEYGLIYYLMFLALISVNLGIINLFPLP
VLDGGHLLFLAIEKLKGGPVSERVQDFSYRIGSILLVLLMGLALFNDFSRL

Specific function: Degrades both heat shock sigma factors rpoE and rpoH [H]

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=451, Percent_Identity=75.3880266075388, Blast_Score=665, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49629; Mature: 49629

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHFFWILAAFIVALGVLITVHEFGHFWVARRCGVTVERFSIGFGRALWRRRDKRGTEYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCCCEEE
IAAIPLGGYVKMLDERVDTVAPERRHEAFNHKTVWQRAAIIAAGPVFNFLFAIFAYWLVF
EEEECCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LIGVPSYRPVIGEVAPHSIAAQAEISPGMELKSVDGIETPDWDSVRLQLIDKIGDGETTL
HHCCCCCCCHHHCCCCCCEEECCCCCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCCCEE
GVASFGSQSAERKTLDLCDWQFEPNRQDAIVALGIIRLGPRIEPVLAEVQPGSAAMKAGL
EEHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEHHHCCCCCCHHHHCCCCCHHHHHHHH
QAGDRIVKVDGQPVTAWQLFVTRVRDNPGRPLQVGIDRHGEARDITLQPDSKPVGKGEVE
CCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCC
GFAGVVPKIIPLPAEYKIVRQYGPLPALARASEKTWQLMRLTVSMLGKLITGDVKLNNLS
CHHHCCHHHCCCCCCHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEECCC
GPISIAQGAGMSAEYGLIYYLMFLALISVNLGIINLFPLPVLDGGHLLFLAIEKLKGGPV
CCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCEEEEEEEHHCCCCH
SERVQDFSYRIGSILLVLLMGLALFNDFSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLHFFWILAAFIVALGVLITVHEFGHFWVARRCGVTVERFSIGFGRALWRRRDKRGTEYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCCCEEE
IAAIPLGGYVKMLDERVDTVAPERRHEAFNHKTVWQRAAIIAAGPVFNFLFAIFAYWLVF
EEEECCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LIGVPSYRPVIGEVAPHSIAAQAEISPGMELKSVDGIETPDWDSVRLQLIDKIGDGETTL
HHCCCCCCCHHHCCCCCCEEECCCCCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCCCEE
GVASFGSQSAERKTLDLCDWQFEPNRQDAIVALGIIRLGPRIEPVLAEVQPGSAAMKAGL
EEHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEHHHCCCCCCHHHHCCCCCHHHHHHHH
QAGDRIVKVDGQPVTAWQLFVTRVRDNPGRPLQVGIDRHGEARDITLQPDSKPVGKGEVE
CCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCC
GFAGVVPKIIPLPAEYKIVRQYGPLPALARASEKTWQLMRLTVSMLGKLITGDVKLNNLS
CHHHCCHHHCCCCCCHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEECCC
GPISIAQGAGMSAEYGLIYYLMFLALISVNLGIINLFPLPVLDGGHLLFLAIEKLKGGPV
CCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCEEEEEEEHHCCCCH
SERVQDFSYRIGSILLVLLMGLALFNDFSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]