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The map label for this gene is ptsG [H]

Identifier: 85059891

GI number: 85059891

Start: 3302001

End: 3303323

Strand: Reverse

Name: ptsG [H]

Synonym: SG1913

Alternate gene names: 85059891

Gene position: 3303323-3302001 (Counterclockwise)

Preceding gene: 85059892

Following gene: 85059890

Centisome position: 79.19

GC content: 51.17

Gene sequence:

>1323_bases
TTGTACGCTTTACAGGGTGATACTAAAGGCGCCGTGTGTAGCTGTCTCATGGGTGTTGATGAGCTGGATTTGGAGGCGGA
ACTGATCATTTCGTCTGCCGATCATTATATCAAGGATGATCTGCAAAGTATTATCGAGTATTTCCGCAGCCAACAGGCTG
ACGCGGGCGTTCTTTCTTTTGAGTCTGTGCATCCAAAATGGTCTTTTGTTAGATTGAATGCGGATAAGCAGGTTGTCGAA
GCCGCCGAGAAAATTTCCATTAGCAGCAATGCCGTGTCGCAGTTCCTCGGTTTCTTCGGCGGCTCGCGTTTCGTGCCGAT
TGTTTGCTCTTTTGCCGCAATTATTGTCGGCGCGGTGATGATGGTTGTGTGGCCCTGGTGTCAGAAAATTATTTTCAGTC
TCGGCGGCCTGGTCGATGCCACCGGATATTTGGGTACGTTTATTTATGGCTTTGTACTGCATATGCTTGGGCTGTTTGGA
TTACATCATATTTTCTATTTGCCCTTCTGGACTACGGCGCTTGGCGGCAGTGAGGTGATAAACGGTCAGCTTTATGAAGG
CACCCAGCGCATCTTTTTCGCGCAGCTGGCGGATCCCAACACCCCGCATTATTATATTGGTACGGCGCGTTTTATGTCCG
GGCGTTTTATTACCATGATGTTTGGACTGCTCGGCGCGTGTCTGGCGATGTATCATGCGGCGCGGCCGGAAAACCGCAAG
CGGGTGGGCGGGTTATTGCTGTTGGCGGCGCTCACCTCCTTTTTGACCGGCATTACCGAACCTATCGAGTTTTCATTTCT
GTTTATCGCTCCGGCGCTGTATGTGCTGCATGTCGTGCTCGAGGCGTTTATGCTGGCCCATATCCTGCACATTACCATTG
GCCAAACTTTCTCCGGTGGCTTTATCGACTTTATCTTGTTCGGCGTTTTGCAGGTCGAGGCGAAAACCCATTGGTTATGG
GTGCCGGTAGTGGGCGTTCCCTGGTTTCTGATTTACTACTTCTCCTTCCGTTATCTGATTCGCCATTTTGATTTTAAAAC
GCCCGGCAGGGAAGACATGGCTGCCGTAAGCGAATCGGTGGTCAGCAGTCAGCGGGCGGAAACGATTATTAAAGCGCTGG
GCGGGCGGGAGAATATTGAAGAGCTGGATTGTTGTGCGACCCGTTTGCGGGTCACGGTGCGGTCCCCGCAAGAGGTGGAT
GAAGCGATGCTGACGCAAAGCGGCGCCCGTGGTGTGATTAAATGTGGTAATAGGGTGCAGGTGATATTCGGCCCTCATGT
CACGGTGATTAAAAATGAAATAGAGGAAGCGATTGCGTCATGA

Upstream 100 bases:

>100_bases
AAGGAAGAAGCTAGAAAAATATTTATCATCCCACAGGTTAGACTTAAAGAACTGGGTCTTAAAACGCTGATAGAGACTAT
TAGTGATTCGACGGGCATAA

Downstream 100 bases:

>100_bases
CTGAGTCTATGCTGACGACGATTAAAGGGAAACTGGTGGTGTCGTGCCAGGCGCTGGAGCAGGAGCCGCTGCACGGTGCA
TCGATAATGGCGCGTATGGC

Product: putative PTS system IIBC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MYALQGDTKGAVCSCLMGVDELDLEAELIISSADHYIKDDLQSIIEYFRSQQADAGVLSFESVHPKWSFVRLNADKQVVE
AAEKISISSNAVSQFLGFFGGSRFVPIVCSFAAIIVGAVMMVVWPWCQKIIFSLGGLVDATGYLGTFIYGFVLHMLGLFG
LHHIFYLPFWTTALGGSEVINGQLYEGTQRIFFAQLADPNTPHYYIGTARFMSGRFITMMFGLLGACLAMYHAARPENRK
RVGGLLLLAALTSFLTGITEPIEFSFLFIAPALYVLHVVLEAFMLAHILHITIGQTFSGGFIDFILFGVLQVEAKTHWLW
VPVVGVPWFLIYYFSFRYLIRHFDFKTPGREDMAAVSESVVSSQRAETIIKALGGRENIEELDCCATRLRVTVRSPQEVD
EAMLTQSGARGVIKCGNRVQVIFGPHVTVIKNEIEEAIAS

Sequences:

>Translated_440_residues
MYALQGDTKGAVCSCLMGVDELDLEAELIISSADHYIKDDLQSIIEYFRSQQADAGVLSFESVHPKWSFVRLNADKQVVE
AAEKISISSNAVSQFLGFFGGSRFVPIVCSFAAIIVGAVMMVVWPWCQKIIFSLGGLVDATGYLGTFIYGFVLHMLGLFG
LHHIFYLPFWTTALGGSEVINGQLYEGTQRIFFAQLADPNTPHYYIGTARFMSGRFITMMFGLLGACLAMYHAARPENRK
RVGGLLLLAALTSFLTGITEPIEFSFLFIAPALYVLHVVLEAFMLAHILHITIGQTFSGGFIDFILFGVLQVEAKTHWLW
VPVVGVPWFLIYYFSFRYLIRHFDFKTPGREDMAAVSESVVSSQRAETIIKALGGRENIEELDCCATRLRVTVRSPQEVD
EAMLTQSGARGVIKCGNRVQVIFGPHVTVIKNEIEEAIAS
>Mature_440_residues
MYALQGDTKGAVCSCLMGVDELDLEAELIISSADHYIKDDLQSIIEYFRSQQADAGVLSFESVHPKWSFVRLNADKQVVE
AAEKISISSNAVSQFLGFFGGSRFVPIVCSFAAIIVGAVMMVVWPWCQKIIFSLGGLVDATGYLGTFIYGFVLHMLGLFG
LHHIFYLPFWTTALGGSEVINGQLYEGTQRIFFAQLADPNTPHYYIGTARFMSGRFITMMFGLLGACLAMYHAARPENRK
RVGGLLLLAALTSFLTGITEPIEFSFLFIAPALYVLHVVLEAFMLAHILHITIGQTFSGGFIDFILFGVLQVEAKTHWLW
VPVVGVPWFLIYYFSFRYLIRHFDFKTPGREDMAAVSESVVSSQRAETIIKALGGRENIEELDCCATRLRVTVRSPQEVD
EAMLTQSGARGVIKCGNRVQVIFGPHVTVIKNEIEEAIAS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=352, Percent_Identity=42.6136363636364, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1787908, Length=350, Percent_Identity=41.1428571428571, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1786894, Length=360, Percent_Identity=40.2777777777778, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 48825; Mature: 48825

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALQGDTKGAVCSCLMGVDELDLEAELIISSADHYIKDDLQSIIEYFRSQQADAGVLSF
CCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEE
ESVHPKWSFVRLNADKQVVEAAEKISISSNAVSQFLGFFGGSRFVPIVCSFAAIIVGAVM
CCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MVVWPWCQKIIFSLGGLVDATGYLGTFIYGFVLHMLGLFGLHHIFYLPFWTTALGGSEVI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
NGQLYEGTQRIFFAQLADPNTPHYYIGTARFMSGRFITMMFGLLGACLAMYHAARPENRK
CCHHHHCHHHHEEEECCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHH
RVGGLLLLAALTSFLTGITEPIEFSFLFIAPALYVLHVVLEAFMLAHILHITIGQTFSGG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
FIDFILFGVLQVEAKTHWLWVPVVGVPWFLIYYFSFRYLIRHFDFKTPGREDMAAVSESV
HHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VSSQRAETIIKALGGRENIEELDCCATRLRVTVRSPQEVDEAMLTQSGARGVIKCGNRVQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEECCHHHHHHHHHHCCCCCCCEECCCEEE
VIFGPHVTVIKNEIEEAIAS
EEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MYALQGDTKGAVCSCLMGVDELDLEAELIISSADHYIKDDLQSIIEYFRSQQADAGVLSF
CCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEE
ESVHPKWSFVRLNADKQVVEAAEKISISSNAVSQFLGFFGGSRFVPIVCSFAAIIVGAVM
CCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MVVWPWCQKIIFSLGGLVDATGYLGTFIYGFVLHMLGLFGLHHIFYLPFWTTALGGSEVI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
NGQLYEGTQRIFFAQLADPNTPHYYIGTARFMSGRFITMMFGLLGACLAMYHAARPENRK
CCHHHHCHHHHEEEECCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHH
RVGGLLLLAALTSFLTGITEPIEFSFLFIAPALYVLHVVLEAFMLAHILHITIGQTFSGG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
FIDFILFGVLQVEAKTHWLWVPVVGVPWFLIYYFSFRYLIRHFDFKTPGREDMAAVSESV
HHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VSSQRAETIIKALGGRENIEELDCCATRLRVTVRSPQEVDEAMLTQSGARGVIKCGNRVQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEECCHHHHHHHHHHCCCCCCCEECCCEEE
VIFGPHVTVIKNEIEEAIAS
EEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]