Click here to switch to the map view.

The map label for this gene is iscR

Identifier: 85059748

GI number: 85059748

Start: 3025216

End: 3025713

Strand: Reverse

Name: iscR

Synonym: SG1770

Alternate gene names: 85059748

Gene position: 3025713-3025216 (Counterclockwise)

Preceding gene: 85059749

Following gene: 85059747

Centisome position: 72.54

GC content: 58.84

Gene sequence:

>498_bases
ATGAGACTGACTTCCAAAGGCCGCTATGCGGTCACCGCAATGCTTGATGTCGCCCTCCATTCCGGTAAGGGGCCTGTGCC
GCTCGCCGAAATTTCCGAGCGTCAGGGCATTTCCCTTTCCTATTTGGAACAGCTTTTCTCCCGCCTTCGCAAGCATGAGC
TGGTGGCCAGCGTGCGGGGACCCGGCGGCGGCTATTTGCTGGGGCGTGACTCTGATCAGATTGCCGTCGGCGCGGTTATC
ACTGCCGTGGATGAATCCGTAGACGCCACGCGTTGCCAGGGTAAAGAAGGCTGCCAAGGTGGCGACCGCTGCCTGACCCA
CGTGCTTTGGCGCGATCTCAGCGTGCGCATCAGCGAGTTTCTCAACAACATTACCCTGGCAGAACTGGTCAGTAATGAAG
AGATCCTCGATGTCGTCGATCGCCAGGACAACGATACCCGTCGTCCGCTTACCAACGGCCGGCCGCAGGAAACGATTAAC
GTCAACCTGCACGCTTGA

Upstream 100 bases:

>100_bases
AAGGGAATAAATACTTGAGCAAATTACTCGGTTAAATAGTTGACTATTTTAGTCAGAAATGTCAGACTTTTGCTACGTTA
TTTTCACCGGTATTCTGATT

Downstream 100 bases:

>100_bases
GTACAATAAGGGCATCCGCTGTTATTGATGCCTGGAGTTAATGCTTCATGAAATTACCGATTTATCTTGATTACTCTGCC
ACTACGCCGGTCGATCCGCG

Product: DNA-binding transcriptional regulator IscR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRLTSKGRYAVTAMLDVALHSGKGPVPLAEISERQGISLSYLEQLFSRLRKHELVASVRGPGGGYLLGRDSDQIAVGAVI
TAVDESVDATRCQGKEGCQGGDRCLTHVLWRDLSVRISEFLNNITLAELVSNEEILDVVDRQDNDTRRPLTNGRPQETIN
VNLHA

Sequences:

>Translated_165_residues
MRLTSKGRYAVTAMLDVALHSGKGPVPLAEISERQGISLSYLEQLFSRLRKHELVASVRGPGGGYLLGRDSDQIAVGAVI
TAVDESVDATRCQGKEGCQGGDRCLTHVLWRDLSVRISEFLNNITLAELVSNEEILDVVDRQDNDTRRPLTNGRPQETIN
VNLHA
>Mature_165_residues
MRLTSKGRYAVTAMLDVALHSGKGPVPLAEISERQGISLSYLEQLFSRLRKHELVASVRGPGGGYLLGRDSDQIAVGAVI
TAVDESVDATRCQGKEGCQGGDRCLTHVLWRDLSVRISEFLNNITLAELVSNEEILDVVDRQDNDTRRPLTNGRPQETIN
VNLHA

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788880, Length=166, Percent_Identity=74.6987951807229, Blast_Score=213, Evalue=7e-57,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): ISCR_SODGM (Q2NS30)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455450.1
- ProteinModelPortal:   Q2NS30
- STRING:   Q2NS30
- GeneID:   3866929
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1770
- NMPDR:   fig|343509.6.peg.3777
- eggNOG:   COG1959
- HOGENOM:   HBG725923
- OMA:   QHISLSY
- PhylomeDB:   Q2NS30
- ProtClustDB:   PRK10857
- BioCyc:   SGLO343509:SG1770-MONOMER
- HAMAP:   MF_01176
- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR02010
- TIGRFAMs:   TIGR00738

Pfam domain/function: PF02082 Rrf2

EC number: NA

Molecular weight: Translated: 18080; Mature: 18080

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS01332 HTH_RRF2_1; PS51197 HTH_RRF2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTSKGRYAVTAMLDVALHSGKGPVPLAEISERQGISLSYLEQLFSRLRKHELVASVRG
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
PGGGYLLGRDSDQIAVGAVITAVDESVDATRCQGKEGCQGGDRCLTHVLWRDLSVRISEF
CCCCEEEECCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LNNITLAELVSNEEILDVVDRQDNDTRRPLTNGRPQETINVNLHA
HCCCHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MRLTSKGRYAVTAMLDVALHSGKGPVPLAEISERQGISLSYLEQLFSRLRKHELVASVRG
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
PGGGYLLGRDSDQIAVGAVITAVDESVDATRCQGKEGCQGGDRCLTHVLWRDLSVRISEF
CCCCEEEECCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LNNITLAELVSNEEILDVVDRQDNDTRRPLTNGRPQETINVNLHA
HCCCHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA