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The map label for this gene is ompR [H]

Identifier: 85059682

GI number: 85059682

Start: 2913332

End: 2914123

Strand: Reverse

Name: ompR [H]

Synonym: SG1704

Alternate gene names: 85059682

Gene position: 2914123-2913332 (Counterclockwise)

Preceding gene: 85059683

Following gene: 85059673

Centisome position: 69.86

GC content: 55.43

Gene sequence:

>792_bases
ATGAAAATTTTGCTGGTTGATGACGATCGGGAACTGGGCAAAATGCTGAGCAAATATCTGACCGCGGAAGGTTTTGATAC
AACATTGGTGCTAACCGGCCAGGAAGGTGTGGACGGCGCGCTTTCCGGCGACTATACCGCTATGATTCTGGATATCATGC
TGCCGGATATGAGCGGCACCGATGTTTTGCACCAGGTTCGCAAGAGTAGCCGCATGCCGATTATCATGTTGACCGCGAAA
GGCGATAATATTGATCGCGTCATCGGCCTGGAAATGGGGGCGGACGATTATATGCCCAAGCCCTGTTATCCCCGTGAATT
GGTCGCGCGGCTGCGCGCAGTGCTGCGCCGTTTCGACGAGCGTCCGGAGCAGCCGGCCGAGGCGGGCGTGGCGAGTTTTG
GCGATTTGCTGCTGAACCCCGCGACCCGCACCAGTCTCTGGCAGGGTAAACCGTTTGACCTTACCGCCTCTGAATTTAAC
CTGCTGGAGTTGCTTATCCGCGCGCCCGACCGGGTGGTATCCAAAGATGACCTGTCGGAAAAGGGCTGGGTCGGTGCCGC
GAAGCCTATGATCGCAGCGTTGATGTGCACATCAGCAATATCCGCCAAAAACTGTCACTGTTGCCCGGCAGCAGCCTGGG
TATTGAAACGGTACGCAGTATCGGTTACCGGATCCGTTGATGAGACTACGCGGGCGTTTGTTCTGGAAGATCCTGCTATG
GTTCTAGCTGATTTTTCTACTGATTACCCAGGGGCTGTGGGTTGTTTTCATCCTGTACGGCAACCGCCATGA

Upstream 100 bases:

>100_bases
GTTGCAGGTCAAACAGTGGCAGGTCTCTGGCCTGGTGAAATAAGGAAGGCTGTCTGGCGATAACGCAGGAGAGCAATGGC
GTGGTATGTGGAGAGAGAAA

Downstream 100 bases:

>100_bases
ACCGTCGGAAGAATCTATCGCCCGGCGCTTTATCAATTTGCAGATGGTATCGGCTGAGTCGGCGCTGAAAGCGGACGGTG
AGCAGACCCTGCTGACCGCC

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKILLVDDDRELGKMLSKYLTAEGFDTTLVLTGQEGVDGALSGDYTAMILDIMLPDMSGTDVLHQVRKSSRMPIIMLTAK
GDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFDERPEQPAEAGVASFGDLLLNPATRTSLWQGKPFDLTASEFN
LLELLIRAPDRVVSKDDLSEKGWVGAAKPMIAALMCTSAISAKNCHCCPAAAWVLKRYAVSVTGSVDETTRAFVLEDPAM
VLADFSTDYPGAVGCFHPVRQPP

Sequences:

>Translated_263_residues
MKILLVDDDRELGKMLSKYLTAEGFDTTLVLTGQEGVDGALSGDYTAMILDIMLPDMSGTDVLHQVRKSSRMPIIMLTAK
GDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFDERPEQPAEAGVASFGDLLLNPATRTSLWQGKPFDLTASEFN
LLELLIRAPDRVVSKDDLSEKGWVGAAKPMIAALMCTSAISAKNCHCCPAAAWVLKRYAVSVTGSVDETTRAFVLEDPAM
VLADFSTDYPGAVGCFHPVRQPP
>Mature_263_residues
MKILLVDDDRELGKMLSKYLTAEGFDTTLVLTGQEGVDGALSGDYTAMILDIMLPDMSGTDVLHQVRKSSRMPIIMLTAK
GDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFDERPEQPAEAGVASFGDLLLNPATRTSLWQGKPFDLTASEFN
LLELLIRAPDRVVSKDDLSEKGWVGAAKPMIAALMCTSAISAKNCHCCPAAAWVLKRYAVSVTGSVDETTRAFVLEDPAM
VLADFSTDYPGAVGCFHPVRQPP

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=181, Percent_Identity=45.8563535911602, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI2367329, Length=183, Percent_Identity=42.6229508196721, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=188, Percent_Identity=39.3617021276596, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788394, Length=177, Percent_Identity=37.8531073446328, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789402, Length=182, Percent_Identity=37.9120879120879, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790860, Length=186, Percent_Identity=37.0967741935484, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786599, Length=185, Percent_Identity=33.5135135135135, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787229, Length=179, Percent_Identity=33.5195530726257, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082012, Length=183, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790552, Length=167, Percent_Identity=35.9281437125749, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786911, Length=182, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790863, Length=217, Percent_Identity=26.7281105990783, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787375, Length=186, Percent_Identity=30.1075268817204, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI145693140, Length=185, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28727; Mature: 28727

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLVDDDRELGKMLSKYLTAEGFDTTLVLTGQEGVDGALSGDYTAMILDIMLPDMSGT
CEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHEEHHCCCCCCH
DVLHQVRKSSRMPIIMLTAKGDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFDE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
RPEQPAEAGVASFGDLLLNPATRTSLWQGKPFDLTASEFNLLELLIRAPDRVVSKDDLSE
CCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCCCC
KGWVGAAKPMIAALMCTSAISAKNCHCCPAAAWVLKRYAVSVTGSVDETTRAFVLEDPAM
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCCCCCCEEEEEECCCE
VLADFSTDYPGAVGCFHPVRQPP
EEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKILLVDDDRELGKMLSKYLTAEGFDTTLVLTGQEGVDGALSGDYTAMILDIMLPDMSGT
CEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHEEHHCCCCCCH
DVLHQVRKSSRMPIIMLTAKGDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFDE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
RPEQPAEAGVASFGDLLLNPATRTSLWQGKPFDLTASEFNLLELLIRAPDRVVSKDDLSE
CCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCCCC
KGWVGAAKPMIAALMCTSAISAKNCHCCPAAAWVLKRYAVSVTGSVDETTRAFVLEDPAM
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCCCCCCEEEEEECCCE
VLADFSTDYPGAVGCFHPVRQPP
EEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]