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The map label for this gene is accD

Identifier: 85059595

GI number: 85059595

Start: 2773087

End: 2774007

Strand: Reverse

Name: accD

Synonym: SG1617

Alternate gene names: 85059595

Gene position: 2774007-2773087 (Counterclockwise)

Preceding gene: 85059596

Following gene: 85059594

Centisome position: 66.5

GC content: 60.8

Gene sequence:

>921_bases
ATGAGCTGGATTGAACGAATTCTCAATAAGAGCACTATCACCTCGGCGCGCAGGGCGAACATTCCCGAAGGCGTATGGAC
CAAGTGTGATAGCTGTGGCCAGGTGCTGTATCGCGCGGAGCTGGAACGCAATCTGGAGGTCTGCCCGAAGTGCGATCACC
ACATGCGGATGACCGCGCGCGCGCGCCTGCACGCTTTCCTGGATAAAGGAAGCGAGTCTGAGCTCGGTAGCGAGCTGGAG
CCGAAAGATATCCTGAAATTCAGGGACTCGAAAAAGTACAAGGATCGCCTGGCGGCGGCCCAGAAAGCCACTGACGAGAA
AGATGCGCTGGTGGTGATGAAAGGCGAGTTGTACGGCATGCCGGTGGTGGTGGCGTCATTCGAGTTCGCCTTTATCGGCG
GTTCGATGTCCTCGGTGGTCGGCGCGCGTTTCGTGCGCGCGGTCGAGCAGGCGCTTGCGGACGACTGTCCTCTGGTGTGC
TTTTCCGCCAGCGGTGGCGCCCGCATGCAGGAAGCGCTGATGTCGTTGATGCAGATGGCCAAGACCAGCGCCGCGCTGGC
GCGGCTGCGCGAACGGCGATTGCCCTATATTTCGGTTTTGACTGACCCCACCATGGGCGGCGTTTCGGCCAGTCTGGCGA
TGCTGGGCGATCTGAACGTTGCCGAGCCGAAAGCGCTGATTGGCTTCGCCGGTCCGCGGGTGATAGAACAGACGGTACGC
GAAAAACTGCCGGCCGGTTTCCAGCGCAGTGAATTCCTGCTGGAAAAGGGCGCTATCGATCTCATCGTGCGCCGTCCAGA
AATGCGTCTGCGTCTGGCCAGTCTGCTGGCAAAACTGACCAACCGGCCCCAGCCGCAGGACCCATTGCCGCACGAGCCGC
GCCCTGATGCGGTCCCAGAGGATCATCAGGACGAGGTATAA

Upstream 100 bases:

>100_bases
CCGGCGGGGAGCGTGCGAGACGGCGGCCCTCCCGCCGCGGTTAAAGGTCAATTAGATATAGCGGACTGGCGGATGCCAGG
TTCAAACAGAAAGGTTATCG

Downstream 100 bases:

>100_bases
AGGGCGGCGTAAGCCTGCCCGCAGCCATCAGCCGGGGGCACGCTTAGTGAAAACCCAGCATAAGCCAATGAACGGACGTA
TGGAAAATCTGCCTATCCCC

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSWIERILNKSTITSARRANIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMTARARLHAFLDKGSESELGSELE
PKDILKFRDSKKYKDRLAAAQKATDEKDALVVMKGELYGMPVVVASFEFAFIGGSMSSVVGARFVRAVEQALADDCPLVC
FSASGGARMQEALMSLMQMAKTSAALARLRERRLPYISVLTDPTMGGVSASLAMLGDLNVAEPKALIGFAGPRVIEQTVR
EKLPAGFQRSEFLLEKGAIDLIVRRPEMRLRLASLLAKLTNRPQPQDPLPHEPRPDAVPEDHQDEV

Sequences:

>Translated_306_residues
MSWIERILNKSTITSARRANIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMTARARLHAFLDKGSESELGSELE
PKDILKFRDSKKYKDRLAAAQKATDEKDALVVMKGELYGMPVVVASFEFAFIGGSMSSVVGARFVRAVEQALADDCPLVC
FSASGGARMQEALMSLMQMAKTSAALARLRERRLPYISVLTDPTMGGVSASLAMLGDLNVAEPKALIGFAGPRVIEQTVR
EKLPAGFQRSEFLLEKGAIDLIVRRPEMRLRLASLLAKLTNRPQPQDPLPHEPRPDAVPEDHQDEV
>Mature_305_residues
SWIERILNKSTITSARRANIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMTARARLHAFLDKGSESELGSELEP
KDILKFRDSKKYKDRLAAAQKATDEKDALVVMKGELYGMPVVVASFEFAFIGGSMSSVVGARFVRAVEQALADDCPLVCF
SASGGARMQEALMSLMQMAKTSAALARLRERRLPYISVLTDPTMGGVSASLAMLGDLNVAEPKALIGFAGPRVIEQTVRE
KLPAGFQRSEFLLEKGAIDLIVRRPEMRLRLASLLAKLTNRPQPQDPLPHEPRPDAVPEDHQDEV

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=305, Percent_Identity=82.9508196721311, Blast_Score=514, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI25147359, Length=190, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147362, Length=190, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_SODGM (Q2NSI3)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455297.1
- ProteinModelPortal:   Q2NSI3
- SMR:   Q2NSI3
- STRING:   Q2NSI3
- GeneID:   3867795
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1617
- NMPDR:   fig|343509.6.peg.3445
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- PhylomeDB:   Q2NSI3
- ProtClustDB:   PRK05654
- BioCyc:   SGLO343509:SG1617-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 33878; Mature: 33746

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWIERILNKSTITSARRANIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMTAR
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ARLHAFLDKGSESELGSELEPKDILKFRDSKKYKDRLAAAQKATDEKDALVVMKGELYGM
HHHHHHHHCCCHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
PVVVASFEFAFIGGSMSSVVGARFVRAVEQALADDCPLVCFSASGGARMQEALMSLMQMA
CHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
KTSAALARLRERRLPYISVLTDPTMGGVSASLAMLGDLNVAEPKALIGFAGPRVIEQTVR
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHH
EKLPAGFQRSEFLLEKGAIDLIVRRPEMRLRLASLLAKLTNRPQPQDPLPHEPRPDAVPE
HHCCCCCCHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DHQDEV
CCCCCC
>Mature Secondary Structure 
SWIERILNKSTITSARRANIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMTAR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ARLHAFLDKGSESELGSELEPKDILKFRDSKKYKDRLAAAQKATDEKDALVVMKGELYGM
HHHHHHHHCCCHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
PVVVASFEFAFIGGSMSSVVGARFVRAVEQALADDCPLVCFSASGGARMQEALMSLMQMA
CHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
KTSAALARLRERRLPYISVLTDPTMGGVSASLAMLGDLNVAEPKALIGFAGPRVIEQTVR
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHH
EKLPAGFQRSEFLLEKGAIDLIVRRPEMRLRLASLLAKLTNRPQPQDPLPHEPRPDAVPE
HHCCCCCCHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DHQDEV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA