| Definition | Sodalis glossinidius str. 'morsitans', complete genome. |
|---|---|
| Accession | NC_007712 |
| Length | 4,171,146 |
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The map label for this gene is trpE [H]
Identifier: 85059380
GI number: 85059380
Start: 2326021
End: 2327589
Strand: Reverse
Name: trpE [H]
Synonym: SG1402
Alternate gene names: 85059380
Gene position: 2327589-2326021 (Counterclockwise)
Preceding gene: 85059385
Following gene: 85059379
Centisome position: 55.8
GC content: 59.97
Gene sequence:
>1569_bases ATGCCAACCACAACCAGTCAGTACCAGATAGAATTGCTGCACGCGCAGACCCCTTACCGCCCCGACACGACGGCCATGTT CAATCAGTTGTGCGGCGCGCGGCCCGCGACGCTATTGCTGGAATCGGCCGAGATCGATAAGAAGCATGATCTGGAAAGCA TGATGGTGGTGGATAGTGCGCTGCGTATCACCGCCCTTGGCCAGACCGTCACGCTACAGGCGCTGAGCGGCAACGGCGCT GCGCTGTTGCCGCTATTGGATGCCGCCTTAACCGAGGAGGTCACGATCATCGCCCATCCCTATGGCCGTGAATTAACCTT CCCACCGTCGGTACAAGACGTGGATGAGGATGCCCGCCTGCGCTCGCTGTCGGTATTCGATTGCCTGCGCCTGCTCCTGA CGCTGGTCGGTCAGCCGCCGGACGCGCTGAAAGCGATGTTTGTCGGCGGGCTATTCGCCTATGATCTCGTTGCAGGCTTT GAATCTCTGCCGCCGCTGCGTCCTGGACAGCTCTGCCCCGATTACTGCTTCTATCTGGCGGAAACGCTGTTGATCCTCGA TCATCAGCAACAAAGCTGCGCACTGCAATGCAGCCTGTTCAGCCCCAGTCCGTCGGAGAAGCAGCGGTTGCAGCACCGCC TTGAGCAATTGCAGCATCAGCTCACCCAAGCGCCGGAGCCCATTCCGCATCAGGTTATCGACACCATGACATTGACCTGC AGCCAGAGCGACGAAGAGTACAGCCAGGTCGTACGCCGGATGCAGCAGGCGATCCGCGAAGGGGAAATTTTCCAGGTCGT GCCTTCGCGGCGCTTCTCACTCCCCTGTCCTTCGGCGCTCGCCGCCTACCATACCTTGAAGAAAAGCAATCCCAGCCCGT ATATGTTTTTTATGCAGGATAATGAGTTCACCCTGTTTGGCGCCTCGCCGGAAAGCTTGCTGAAATACGCCCCTGATACC GGACAGATTGAAATCTACCCCATCGCCGGCACCCGGCCACGCGGACAGCGCGCCAACGGCACGTTGGATGCCGATCTCGA CAGCCGCATTGAACTTGAAATGCGCGCCGACCATAAAGAACTGGCCGAACATTTGATGCTGGTGGATTTGGCGCGCAATG ATCTGGCGCGTATCTGCGAGCCGGGCACCCGCTACGTGGCGGATTTGATCAAAGTTGATCGTTACTCCTTCGTGATGCAT TTGGTCTCTCGGGTCGTCGGCCAGCTGCGCGCCGATCTTGACGTACTGCACGCCTACCGCGCCTGCATGAATATGGGCAC CTTGAGCGGGGCGCCGAAAGTCCGCGCCATGCAGCTTATCGCCGAGGCAGAAGGCGAACGCCGCGGCAGCTACGGCGGCG CGATTGGCTATTTTACCGCCGCCGGCGCGCTCGATACCTGCATTGTCATCCGTTCCGCCTACGTCGAAGACGGCATCGCC ACGGTGCAGGCCGGCGCAGGCGTGGTACTGGATTCCGTTCCACAGGCAGAAGCCGACGAAAGCCGCAACAAAGCGCGTGC CGTTTTGCGCGCCATTGCTACCGCCCACGACGCAAAGGAGCTGTTCTGA
Upstream 100 bases:
>100_bases GAAATCATGCGTCGCTGTCATCAGACAGAGCACGATCCCAAATAGCCCGCTGCGTTAGCGGGTTTTTTATGGACGACAAT CAGGAAAACAGATAATGCCA
Downstream 100 bases:
>100_bases TGGCCGACATCCTGTTACTCGATAATATCGACTCGTTTACCTATAACCTGGTGGATCAGCTGCGCGCCAACGGTCACCGA GTAGTGATTTACCGCAACCG
Product: anthranilate synthase component I
Products: NA
Alternate protein names: Anthranilate synthase component I [H]
Number of amino acids: Translated: 522; Mature: 521
Protein sequence:
>522_residues MPTTTSQYQIELLHAQTPYRPDTTAMFNQLCGARPATLLLESAEIDKKHDLESMMVVDSALRITALGQTVTLQALSGNGA ALLPLLDAALTEEVTIIAHPYGRELTFPPSVQDVDEDARLRSLSVFDCLRLLLTLVGQPPDALKAMFVGGLFAYDLVAGF ESLPPLRPGQLCPDYCFYLAETLLILDHQQQSCALQCSLFSPSPSEKQRLQHRLEQLQHQLTQAPEPIPHQVIDTMTLTC SQSDEEYSQVVRRMQQAIREGEIFQVVPSRRFSLPCPSALAAYHTLKKSNPSPYMFFMQDNEFTLFGASPESLLKYAPDT GQIEIYPIAGTRPRGQRANGTLDADLDSRIELEMRADHKELAEHLMLVDLARNDLARICEPGTRYVADLIKVDRYSFVMH LVSRVVGQLRADLDVLHAYRACMNMGTLSGAPKVRAMQLIAEAEGERRGSYGGAIGYFTAAGALDTCIVIRSAYVEDGIA TVQAGAGVVLDSVPQAEADESRNKARAVLRAIATAHDAKELF
Sequences:
>Translated_522_residues MPTTTSQYQIELLHAQTPYRPDTTAMFNQLCGARPATLLLESAEIDKKHDLESMMVVDSALRITALGQTVTLQALSGNGA ALLPLLDAALTEEVTIIAHPYGRELTFPPSVQDVDEDARLRSLSVFDCLRLLLTLVGQPPDALKAMFVGGLFAYDLVAGF ESLPPLRPGQLCPDYCFYLAETLLILDHQQQSCALQCSLFSPSPSEKQRLQHRLEQLQHQLTQAPEPIPHQVIDTMTLTC SQSDEEYSQVVRRMQQAIREGEIFQVVPSRRFSLPCPSALAAYHTLKKSNPSPYMFFMQDNEFTLFGASPESLLKYAPDT GQIEIYPIAGTRPRGQRANGTLDADLDSRIELEMRADHKELAEHLMLVDLARNDLARICEPGTRYVADLIKVDRYSFVMH LVSRVVGQLRADLDVLHAYRACMNMGTLSGAPKVRAMQLIAEAEGERRGSYGGAIGYFTAAGALDTCIVIRSAYVEDGIA TVQAGAGVVLDSVPQAEADESRNKARAVLRAIATAHDAKELF >Mature_521_residues PTTTSQYQIELLHAQTPYRPDTTAMFNQLCGARPATLLLESAEIDKKHDLESMMVVDSALRITALGQTVTLQALSGNGAA LLPLLDAALTEEVTIIAHPYGRELTFPPSVQDVDEDARLRSLSVFDCLRLLLTLVGQPPDALKAMFVGGLFAYDLVAGFE SLPPLRPGQLCPDYCFYLAETLLILDHQQQSCALQCSLFSPSPSEKQRLQHRLEQLQHQLTQAPEPIPHQVIDTMTLTCS QSDEEYSQVVRRMQQAIREGEIFQVVPSRRFSLPCPSALAAYHTLKKSNPSPYMFFMQDNEFTLFGASPESLLKYAPDTG QIEIYPIAGTRPRGQRANGTLDADLDSRIELEMRADHKELAEHLMLVDLARNDLARICEPGTRYVADLIKVDRYSFVMHL VSRVVGQLRADLDVLHAYRACMNMGTLSGAPKVRAMQLIAEAEGERRGSYGGAIGYFTAAGALDTCIVIRSAYVEDGIAT VQAGAGVVLDSVPQAEADESRNKARAVLRAIATAHDAKELF
Specific function: Tryptophan biosynthesis; first step. [C]
COG id: COG0147
COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the anthranilate synthase component I family [H]
Homologues:
Organism=Escherichia coli, GI1787518, Length=518, Percent_Identity=72.5868725868726, Blast_Score=738, Evalue=0.0, Organism=Escherichia coli, GI1788114, Length=369, Percent_Identity=32.2493224932249, Blast_Score=172, Evalue=6e-44, Organism=Escherichia coli, GI87082077, Length=321, Percent_Identity=28.0373831775701, Blast_Score=72, Evalue=6e-14, Organism=Saccharomyces cerevisiae, GI6320935, Length=379, Percent_Identity=36.4116094986807, Blast_Score=219, Evalue=7e-58, Organism=Saccharomyces cerevisiae, GI6324361, Length=411, Percent_Identity=25.5474452554745, Blast_Score=93, Evalue=9e-20,
Paralogues:
None
Copy number: 700 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005801 - InterPro: IPR019999 - InterPro: IPR006805 - InterPro: IPR005257 - InterPro: IPR015890 [H]
Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]
EC number: =4.1.3.27 [H]
Molecular weight: Translated: 57494; Mature: 57363
Theoretical pI: Translated: 5.04; Mature: 5.04
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 2.1 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPTTTSQYQIELLHAQTPYRPDTTAMFNQLCGARPATLLLESAEIDKKHDLESMMVVDSA CCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCHHHHHHHHHHHHH LRITALGQTVTLQALSGNGAALLPLLDAALTEEVTIIAHPYGRELTFPPSVQDVDEDARL HHEEECCCEEEEEEECCCCEEHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHH RSLSVFDCLRLLLTLVGQPPDALKAMFVGGLFAYDLVAGFESLPPLRPGQLCPDYCFYLA HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH ETLLILDHQQQSCALQCSLFSPSPSEKQRLQHRLEQLQHQLTQAPEPIPHQVIDTMTLTC HHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEE SQSDEEYSQVVRRMQQAIREGEIFQVVPSRRFSLPCPSALAAYHTLKKSNPSPYMFFMQD CCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEC NEFTLFGASPESLLKYAPDTGQIEIYPIAGTRPRGQRANGTLDADLDSRIELEMRADHKE CEEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHH LAEHLMLVDLARNDLARICEPGTRYVADLIKVDRYSFVMHLVSRVVGQLRADLDVLHAYR HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ACMNMGTLSGAPKVRAMQLIAEAEGERRGSYGGAIGYFTAAGALDTCIVIRSAYVEDGIA HHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH TVQAGAGVVLDSVPQAEADESRNKARAVLRAIATAHDAKELF HHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure PTTTSQYQIELLHAQTPYRPDTTAMFNQLCGARPATLLLESAEIDKKHDLESMMVVDSA CCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCHHHHHHHHHHHHH LRITALGQTVTLQALSGNGAALLPLLDAALTEEVTIIAHPYGRELTFPPSVQDVDEDARL HHEEECCCEEEEEEECCCCEEHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHH RSLSVFDCLRLLLTLVGQPPDALKAMFVGGLFAYDLVAGFESLPPLRPGQLCPDYCFYLA HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH ETLLILDHQQQSCALQCSLFSPSPSEKQRLQHRLEQLQHQLTQAPEPIPHQVIDTMTLTC HHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEE SQSDEEYSQVVRRMQQAIREGEIFQVVPSRRFSLPCPSALAAYHTLKKSNPSPYMFFMQD CCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEC NEFTLFGASPESLLKYAPDTGQIEIYPIAGTRPRGQRANGTLDADLDSRIELEMRADHKE CEEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHH LAEHLMLVDLARNDLARICEPGTRYVADLIKVDRYSFVMHLVSRVVGQLRADLDVLHAYR HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ACMNMGTLSGAPKVRAMQLIAEAEGERRGSYGGAIGYFTAAGALDTCIVIRSAYVEDGIA HHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH TVQAGAGVVLDSVPQAEADESRNKARAVLRAIATAHDAKELF HHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11371633; 4598537; 366432; 7007652 [H]