Click here to switch to the map view.

The map label for this gene is guaA [H]

Identifier: 85059115

GI number: 85059115

Start: 1888195

End: 1888776

Strand: Reverse

Name: guaA [H]

Synonym: SG1137

Alternate gene names: 85059115

Gene position: 1888776-1888195 (Counterclockwise)

Preceding gene: 85059116

Following gene: 85059114

Centisome position: 45.28

GC content: 58.93

Gene sequence:

>582_bases
ATGACGGCACGGGACCCGGCGCTGCCGCACTGTACTTGGGCACGCAACGATGCGCTCATGCGCGATTATCACGACACCGA
ATGGGGCGTGCCGCAGCATTACGATCGCCTGCTATGGGAAATGCTGATGCTGGAAGGGTTCCAGGCCGGCCTGTCCTGGA
TTACCGTGCTGCGTAAACACGCCGCTTTTCGCGAAGCGTTTTGCGGCTTTGATCCGCACCAGGTTGCGGCGTTTACCGAA
CATGACGTGCAACGTCTGCTTGGCAATCCGGGCATCATCCGCGCCCGTGCGAAGATTGAGGCCACGATCACCGGCGCCCG
CATTTATTGCCAGATGGCAGCTCAAGGGGAATCATTCAGCGACTTTTGCTGGCATTTCACCAACGGTCAGGTGCTGGAGG
GCGACAGGGTGACGCAGATCGCCTCCACGCCTCTTTCAGCGCAGATCTCGGCAGCTCTGAAAAAACGGGGCTTCAAATTC
GTCGGGCCAACAATCGTCTACGCCTGGATACAGGCCGTAGGGATAGTAAACGACCACAGCGCTGAATGCTTTTGCCGGCG
GCGACAAGACGCCGGTTACTGA

Upstream 100 bases:

>100_bases
ACTGTCGCAGCCTGGAAAGAGAACCGTTGCGGCACTCGCCCATGCCGCGTCTTTCAGGGTATGATGCCAAACAACAAATT
GTTCATGCCTGGAGGCGAAA

Downstream 100 bases:

>100_bases
GCGTTGCCGAACCATAGAGTGCGGGCGTTGCCTGGGGGGTGTTATGTGCCCGTCCGGTTTGCGGTCGACCCTCCACCCAG
TCGGGGCACAATCGCCATCA

Product: 3-methyl-adenine DNA glycosylase I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MTARDPALPHCTWARNDALMRDYHDTEWGVPQHYDRLLWEMLMLEGFQAGLSWITVLRKHAAFREAFCGFDPHQVAAFTE
HDVQRLLGNPGIIRARAKIEATITGARIYCQMAAQGESFSDFCWHFTNGQVLEGDRVTQIASTPLSAQISAALKKRGFKF
VGPTIVYAWIQAVGIVNDHSAECFCRRRQDAGY

Sequences:

>Translated_193_residues
MTARDPALPHCTWARNDALMRDYHDTEWGVPQHYDRLLWEMLMLEGFQAGLSWITVLRKHAAFREAFCGFDPHQVAAFTE
HDVQRLLGNPGIIRARAKIEATITGARIYCQMAAQGESFSDFCWHFTNGQVLEGDRVTQIASTPLSAQISAALKKRGFKF
VGPTIVYAWIQAVGIVNDHSAECFCRRRQDAGY
>Mature_192_residues
TARDPALPHCTWARNDALMRDYHDTEWGVPQHYDRLLWEMLMLEGFQAGLSWITVLRKHAAFREAFCGFDPHQVAAFTEH
DVQRLLGNPGIIRARAKIEATITGARIYCQMAAQGESFSDFCWHFTNGQVLEGDRVTQIASTPLSAQISAALKKRGFKFV
GPTIVYAWIQAVGIVNDHSAECFCRRRQDAGY

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=181, Percent_Identity=51.9337016574586, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 21833; Mature: 21702

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARDPALPHCTWARNDALMRDYHDTEWGVPQHYDRLLWEMLMLEGFQAGLSWITVLRKH
CCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFREAFCGFDPHQVAAFTEHDVQRLLGNPGIIRARAKIEATITGARIYCQMAAQGESFS
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCEEEEEECCCCCCHH
DFCWHFTNGQVLEGDRVTQIASTPLSAQISAALKKRGFKFVGPTIVYAWIQAVGIVNDHS
HHHEECCCCEEECCCCHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
AECFCRRRQDAGY
HHHHHHHHHCCCC
>Mature Secondary Structure 
TARDPALPHCTWARNDALMRDYHDTEWGVPQHYDRLLWEMLMLEGFQAGLSWITVLRKH
CCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFREAFCGFDPHQVAAFTEHDVQRLLGNPGIIRARAKIEATITGARIYCQMAAQGESFS
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCEEEEEECCCCCCHH
DFCWHFTNGQVLEGDRVTQIASTPLSAQISAALKKRGFKFVGPTIVYAWIQAVGIVNDHS
HHHEECCCCEEECCCCHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
AECFCRRRQDAGY
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]