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The map label for this gene is yicO [H]

Identifier: 85059113

GI number: 85059113

Start: 1884366

End: 1885661

Strand: Reverse

Name: yicO [H]

Synonym: SG1135

Alternate gene names: 85059113

Gene position: 1885661-1884366 (Counterclockwise)

Preceding gene: 85059114

Following gene: 85059110

Centisome position: 45.21

GC content: 57.25

Gene sequence:

>1296_bases
ATGTTGGAAAAATTATTTAAATTAACGGCCCACCGCACCACGGTACGCACCGAGATTGTCGCGGGCCTGACGACCTTTTT
GGCAATGGCTTATATTTTGTTCATTAATCCGACGATCCTCAGCACTACCGGCATGGATAAGGGATCAGTGTTTGTCGCCA
CCTGCCTTGCGGCGGCGATTGGCTCCATGCTGATGGGATTTATTGCCAACTACCCAATCGCCCTGGCGCCCGGTATGGGG
CTGAACGCCTTTTTCACCTATACCGTGGTCCTGCACATGGGTTACACCTGGCAAATCGCGTTGGGTGCGGTGTTCCTATC
GGCTCTGATTTTCTTTGCACTGTCAATTTTCAAAATTCGCGAATGGATTATAACCAGCATCCCTTTGCCGCTGCGTTCGG
GGATTGCCGCGGGCATTGGTCTCTTTCTGGCTATCATCGCGCTCCAGGGCGCCGGCATCGTGGTGGATAATCCGGCGACG
CTGGTCGGCATGGGCGATCTCACCCGGCCTGGCCCGCTGTTTGCCATGCTGGGCTTCATTGTCATCGTGGTGCTGGAAGC
GCGGCGGGTCCCGGGCGCGGTATTAATCGGTATCCTGACGATCACTTTTCTGTCCATCGCGGTGGGCCTCAGTCCGTTTG
CAGGCGTGGTCTCCATGCCGCCGTCGATCGCGCTGACCTTCCTGCAATTGGATATCCGCGGCGCCTTGGACATTTCGCTG
GTGAGCGTGATCTTCGCCTTCCTGTTCGTGGACGTCTTTGACAACTCCGGCACGCTTATCGGGGTAACCAAACGCGCCGG
ACTGGCGGATGAACAGGGCAATATCCCTAAAATGGGCAAAGCACTCGTGGCCGACAGCGCCGCGGCCTTGTTTGGCTCGC
TCCTGGGCACCTCCACCACCACCAGCTATGTTGAATCCGCCGCAGGCGTCAGCGCCGGCGGCCGTACGGGTTTGACGGCG
ATTGTGGTCGGTATCCTGTTCCTGCTCAGCCTGTTTTTTGCTCCGCTGGCTTCAAGCGTGCCCGCTTTCGCCACTGCACC
GGCGCTGCTGTTTGTAGCGGTGCTGATGACTTCCGGCCTGGCGGAAATTGATTGGAAAGATATCACCGTGTCGGCTCCAG
TCACCGTAACGGCCCTGACTATGCCCCTGACGTACTCAATTGCCAACGGCATCGCCTTCGGTTTTATCACCTGGACGCTG
GTGAAATTGCTGACGGGTCGCTACCGGGATCTGAATGTGGCACTGATTGTACTGTCGGTTCTGTTTGTTATCAAGCTGGG
CTGGCTTAGCGCCTGA

Upstream 100 bases:

>100_bases
AATCACCCTTAATCGGGTTTTTTCTGTCCTGCGCCGGTGTCAGAAGAATGGCATAACGATTGCTTGGGCAGTGCAGACAT
CTTCTCAGAGATTAAAACAC

Downstream 100 bases:

>100_bases
CCCGTCAGTGGACCGCCCGGCGCACGCCGACGCGGTCCGCACGCCCTGCGGTGGCGCAGCCCTCCCGGCTCTTGCCGACC
ATCGCGTCGATCCCGCCAGG

Product: putative transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MLEKLFKLTAHRTTVRTEIVAGLTTFLAMAYILFINPTILSTTGMDKGSVFVATCLAAAIGSMLMGFIANYPIALAPGMG
LNAFFTYTVVLHMGYTWQIALGAVFLSALIFFALSIFKIREWIITSIPLPLRSGIAAGIGLFLAIIALQGAGIVVDNPAT
LVGMGDLTRPGPLFAMLGFIVIVVLEARRVPGAVLIGILTITFLSIAVGLSPFAGVVSMPPSIALTFLQLDIRGALDISL
VSVIFAFLFVDVFDNSGTLIGVTKRAGLADEQGNIPKMGKALVADSAAALFGSLLGTSTTTSYVESAAGVSAGGRTGLTA
IVVGILFLLSLFFAPLASSVPAFATAPALLFVAVLMTSGLAEIDWKDITVSAPVTVTALTMPLTYSIANGIAFGFITWTL
VKLLTGRYRDLNVALIVLSVLFVIKLGWLSA

Sequences:

>Translated_431_residues
MLEKLFKLTAHRTTVRTEIVAGLTTFLAMAYILFINPTILSTTGMDKGSVFVATCLAAAIGSMLMGFIANYPIALAPGMG
LNAFFTYTVVLHMGYTWQIALGAVFLSALIFFALSIFKIREWIITSIPLPLRSGIAAGIGLFLAIIALQGAGIVVDNPAT
LVGMGDLTRPGPLFAMLGFIVIVVLEARRVPGAVLIGILTITFLSIAVGLSPFAGVVSMPPSIALTFLQLDIRGALDISL
VSVIFAFLFVDVFDNSGTLIGVTKRAGLADEQGNIPKMGKALVADSAAALFGSLLGTSTTTSYVESAAGVSAGGRTGLTA
IVVGILFLLSLFFAPLASSVPAFATAPALLFVAVLMTSGLAEIDWKDITVSAPVTVTALTMPLTYSIANGIAFGFITWTL
VKLLTGRYRDLNVALIVLSVLFVIKLGWLSA
>Mature_431_residues
MLEKLFKLTAHRTTVRTEIVAGLTTFLAMAYILFINPTILSTTGMDKGSVFVATCLAAAIGSMLMGFIANYPIALAPGMG
LNAFFTYTVVLHMGYTWQIALGAVFLSALIFFALSIFKIREWIITSIPLPLRSGIAAGIGLFLAIIALQGAGIVVDNPAT
LVGMGDLTRPGPLFAMLGFIVIVVLEARRVPGAVLIGILTITFLSIAVGLSPFAGVVSMPPSIALTFLQLDIRGALDISL
VSVIFAFLFVDVFDNSGTLIGVTKRAGLADEQGNIPKMGKALVADSAAALFGSLLGTSTTTSYVESAAGVSAGGRTGLTA
IVVGILFLLSLFFAPLASSVPAFATAPALLFVAVLMTSGLAEIDWKDITVSAPVTVTALTMPLTYSIANGIAFGFITWTL
VKLLTGRYRDLNVALIVLSVLFVIKLGWLSA

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=425, Percent_Identity=51.0588235294118, Blast_Score=440, Evalue=1e-124,
Organism=Escherichia coli, GI1790150, Length=431, Percent_Identity=50.8120649651972, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1790499, Length=429, Percent_Identity=41.025641025641, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI48994909, Length=432, Percent_Identity=40.0462962962963, Blast_Score=279, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45097; Mature: 45097

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKLFKLTAHRTTVRTEIVAGLTTFLAMAYILFINPTILSTTGMDKGSVFVATCLAAAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHHH
GSMLMGFIANYPIALAPGMGLNAFFTYTVVLHMGYTWQIALGAVFLSALIFFALSIFKIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EWIITSIPLPLRSGIAAGIGLFLAIIALQGAGIVVDNPATLVGMGDLTRPGPLFAMLGFI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCCHHHHHHHHH
VIVVLEARRVPGAVLIGILTITFLSIAVGLSPFAGVVSMPPSIALTFLQLDIRGALDISL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHEEECCCCHHHHH
VSVIFAFLFVDVFDNSGTLIGVTKRAGLADEQGNIPKMGKALVADSAAALFGSLLGTSTT
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
TSYVESAAGVSAGGRTGLTAIVVGILFLLSLFFAPLASSVPAFATAPALLFVAVLMTSGL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
AEIDWKDITVSAPVTVTALTMPLTYSIANGIAFGFITWTLVKLLTGRYRDLNVALIVLSV
CCCCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LFVIKLGWLSA
HHHHHHHHCCC
>Mature Secondary Structure
MLEKLFKLTAHRTTVRTEIVAGLTTFLAMAYILFINPTILSTTGMDKGSVFVATCLAAAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHHH
GSMLMGFIANYPIALAPGMGLNAFFTYTVVLHMGYTWQIALGAVFLSALIFFALSIFKIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EWIITSIPLPLRSGIAAGIGLFLAIIALQGAGIVVDNPATLVGMGDLTRPGPLFAMLGFI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCCHHHHHHHHH
VIVVLEARRVPGAVLIGILTITFLSIAVGLSPFAGVVSMPPSIALTFLQLDIRGALDISL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHEEECCCCHHHHH
VSVIFAFLFVDVFDNSGTLIGVTKRAGLADEQGNIPKMGKALVADSAAALFGSLLGTSTT
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
TSYVESAAGVSAGGRTGLTAIVVGILFLLSLFFAPLASSVPAFATAPALLFVAVLMTSGL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
AEIDWKDITVSAPVTVTALTMPLTYSIANGIAFGFITWTLVKLLTGRYRDLNVALIVLSV
CCCCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LFVIKLGWLSA
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]