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The map label for this gene is aspC [H]

Identifier: 85058984

GI number: 85058984

Start: 1658482

End: 1659672

Strand: Reverse

Name: aspC [H]

Synonym: SG1006

Alternate gene names: 85058984

Gene position: 1659672-1658482 (Counterclockwise)

Preceding gene: 85058985

Following gene: 85058977

Centisome position: 39.79

GC content: 58.19

Gene sequence:

>1191_bases
ATGTTTGAATCTATTCCGGTCGCACCGGCGGACCCGATTCTCGGCCTGCTGGATGTCTTTCACGCCGACGATCGTCCCGG
CAAAATCAACCTCGGTATCGGCGTTTACAAGGATGAAACCGGTAATACGCCGGTGCTGACCAGCGTAAAAAAAGCGGAAG
CGCTGTTGCTGGAAAATGAAACCAGCAAAAACTATCTGGGTATCGACGGCCTCGCGGCCTTCGCCGCGGGCACGCAGCGC
CTCCTGTTCGGGTCTGACAGCTCCCTTATCGCCGACGCGCGTGCGCGTAGCGCGCAAACTCCCGGCGGTACCGGTGCCCT
GCGCGTGGCCGCGGATTTTCTGGCGCATAATACCGCCGTGCGCCGCGTTTGGGTAAGCAACCCCAGCTGGCCGAATCACA
AGAACGTTTTCAGCGCCGCAGGACTGGAGGTGTGCCATTACGCCTACTATGACGCCGTTACGCATACGCTTGATTTCACG
GCAATGCTGGCGAGCCTGAGTGAGGCACGGGCCGGCGATGTCGTCTTATTCCACGGCTGTTGCCATAATCCGACCGGTAT
TGATCCCAACCTGCAACAATGGCGCGAACTGGCCGCCCTGTCGGCCCGTCAGGGCTGGCTGCCGCTGTTCGATTTTGCCT
ATCAGGGTTTCGCCCACAGCCTGGAAGACGATGCGGCAGACTTGCGCATTTTCTGCGAAGCGCATCAGGAGCTCATCGTG
TGTAGCTCTTATTCAAAGAATTTTGGTCTGTATAATGAACGCGTCGGCGCCTGTACCTTGATTGCGCCCGACAGCGCGGT
TGCCGATCGCGCCTTCAGCCAGCTGAAGGCCATCATTCGCGCCAATTATTCCAATCCTCCGGCGCACGGTGCCGCCGTGG
TTACCACCATTTTAGCCGACGACGTACTGCGCGCCATGTGGGAGCAAGAGCTTAGGGGTATGCGTGAACGGATCCAACGT
ATGCGCCAGCTGTTCGTCAATACACTTTTGGATAAAGGCGCGCAGCAGGACTTCAGCTTTATCAACCGGCAAAACGGTAT
GTTCTCTTTCAGCGGCCTGAACCAGGAACAGGTGCTGAGGTTGCGTGACCAGTCAGGCATCTATGTGGTGAATTCGGGCC
GTATCAACGTAGCCGGAATGACGCCGGATAACATGGCGCCGCTGTGCGAGGCGATCGTGGCGGTGCTCTGA

Upstream 100 bases:

>100_bases
TGGCCGCCGAAAAATGTGCGGCAAACGGTTGGCAAAGCGCGCTGGTAACGGTAACCTGATAACACTTTTCGCACACTGTG
ACGTTTTGGACACACTTCCC

Downstream 100 bases:

>100_bases
CCACCGGGCGGCCTGTTCAAAGTAGCACGCCGCGGCGGCGGCGCATCCGTCAAGTGAGTCAACAGCACCCGGACGGGAGC
CGGATCGGCACGCCCTCAAT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MFESIPVAPADPILGLLDVFHADDRPGKINLGIGVYKDETGNTPVLTSVKKAEALLLENETSKNYLGIDGLAAFAAGTQR
LLFGSDSSLIADARARSAQTPGGTGALRVAADFLAHNTAVRRVWVSNPSWPNHKNVFSAAGLEVCHYAYYDAVTHTLDFT
AMLASLSEARAGDVVLFHGCCHNPTGIDPNLQQWRELAALSARQGWLPLFDFAYQGFAHSLEDDAADLRIFCEAHQELIV
CSSYSKNFGLYNERVGACTLIAPDSAVADRAFSQLKAIIRANYSNPPAHGAAVVTTILADDVLRAMWEQELRGMRERIQR
MRQLFVNTLLDKGAQQDFSFINRQNGMFSFSGLNQEQVLRLRDQSGIYVVNSGRINVAGMTPDNMAPLCEAIVAVL

Sequences:

>Translated_396_residues
MFESIPVAPADPILGLLDVFHADDRPGKINLGIGVYKDETGNTPVLTSVKKAEALLLENETSKNYLGIDGLAAFAAGTQR
LLFGSDSSLIADARARSAQTPGGTGALRVAADFLAHNTAVRRVWVSNPSWPNHKNVFSAAGLEVCHYAYYDAVTHTLDFT
AMLASLSEARAGDVVLFHGCCHNPTGIDPNLQQWRELAALSARQGWLPLFDFAYQGFAHSLEDDAADLRIFCEAHQELIV
CSSYSKNFGLYNERVGACTLIAPDSAVADRAFSQLKAIIRANYSNPPAHGAAVVTTILADDVLRAMWEQELRGMRERIQR
MRQLFVNTLLDKGAQQDFSFINRQNGMFSFSGLNQEQVLRLRDQSGIYVVNSGRINVAGMTPDNMAPLCEAIVAVL
>Mature_396_residues
MFESIPVAPADPILGLLDVFHADDRPGKINLGIGVYKDETGNTPVLTSVKKAEALLLENETSKNYLGIDGLAAFAAGTQR
LLFGSDSSLIADARARSAQTPGGTGALRVAADFLAHNTAVRRVWVSNPSWPNHKNVFSAAGLEVCHYAYYDAVTHTLDFT
AMLASLSEARAGDVVLFHGCCHNPTGIDPNLQQWRELAALSARQGWLPLFDFAYQGFAHSLEDDAADLRIFCEAHQELIV
CSSYSKNFGLYNERVGACTLIAPDSAVADRAFSQLKAIIRANYSNPPAHGAAVVTTILADDVLRAMWEQELRGMRERIQR
MRQLFVNTLLDKGAQQDFSFINRQNGMFSFSGLNQEQVLRLRDQSGIYVVNSGRINVAGMTPDNMAPLCEAIVAVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=393, Percent_Identity=42.2391857506361, Blast_Score=314, Evalue=8e-86,
Organism=Homo sapiens, GI4504067, Length=400, Percent_Identity=39.75, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI117414139, Length=384, Percent_Identity=29.1666666666667, Blast_Score=156, Evalue=4e-38,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=77.2727272727273, Blast_Score=649, Evalue=0.0,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=40.8060453400504, Blast_Score=315, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI71981858, Length=392, Percent_Identity=38.7755102040816, Blast_Score=314, Evalue=4e-86,
Organism=Caenorhabditis elegans, GI25147133, Length=392, Percent_Identity=38.5204081632653, Blast_Score=312, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17569539, Length=398, Percent_Identity=38.6934673366834, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17569537, Length=395, Percent_Identity=32.9113924050633, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI25147136, Length=208, Percent_Identity=37.5, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17550384, Length=314, Percent_Identity=30.2547770700637, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=36.6995073891626, Blast_Score=275, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6322743, Length=427, Percent_Identity=33.0210772833724, Blast_Score=233, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=39.8989898989899, Blast_Score=304, Evalue=8e-83,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=39.8989898989899, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=40.6015037593985, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=40.6015037593985, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=40.153452685422, Blast_Score=300, Evalue=8e-82,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43207; Mature: 43207

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESIPVAPADPILGLLDVFHADDRPGKINLGIGVYKDETGNTPVLTSVKKAEALLLENE
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCEEHHHHHHHHEEECC
TSKNYLGIDGLAAFAAGTQRLLFGSDSSLIADARARSAQTPGGTGALRVAADFLAHNTAV
CCCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
RRVWVSNPSWPNHKNVFSAAGLEVCHYAYYDAVTHTLDFTAMLASLSEARAGDVVLFHGC
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
CHNPTGIDPNLQQWRELAALSARQGWLPLFDFAYQGFAHSLEDDAADLRIFCEAHQELIV
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEE
CSSYSKNFGLYNERVGACTLIAPDSAVADRAFSQLKAIIRANYSNPPAHGAAVVTTILAD
EECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DVLRAMWEQELRGMRERIQRMRQLFVNTLLDKGAQQDFSFINRQNGMFSFSGLNQEQVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCHHHHHH
LRDQSGIYVVNSGRINVAGMTPDNMAPLCEAIVAVL
EECCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MFESIPVAPADPILGLLDVFHADDRPGKINLGIGVYKDETGNTPVLTSVKKAEALLLENE
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCEEHHHHHHHHEEECC
TSKNYLGIDGLAAFAAGTQRLLFGSDSSLIADARARSAQTPGGTGALRVAADFLAHNTAV
CCCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
RRVWVSNPSWPNHKNVFSAAGLEVCHYAYYDAVTHTLDFTAMLASLSEARAGDVVLFHGC
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
CHNPTGIDPNLQQWRELAALSARQGWLPLFDFAYQGFAHSLEDDAADLRIFCEAHQELIV
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEE
CSSYSKNFGLYNERVGACTLIAPDSAVADRAFSQLKAIIRANYSNPPAHGAAVVTTILAD
EECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DVLRAMWEQELRGMRERIQRMRQLFVNTLLDKGAQQDFSFINRQNGMFSFSGLNQEQVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCHHHHHH
LRDQSGIYVVNSGRINVAGMTPDNMAPLCEAIVAVL
EECCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]