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The map label for this gene is prgH [H]

Identifier: 85058537

GI number: 85058537

Start: 953831

End: 955075

Strand: Reverse

Name: prgH [H]

Synonym: SG0559

Alternate gene names: 85058537

Gene position: 955075-953831 (Counterclockwise)

Preceding gene: 85058558

Following gene: 85058536

Centisome position: 22.9

GC content: 49.88

Gene sequence:

>1245_bases
ATGTCTGACGTTTTCACTGATAATAAAAATGAAGCCGATGAATTAATCTATACGCTTAAAATCTTGTTTGGCCCGATGTA
CGGTAGCGATCTTATTTTACCGCCCAATACGTATTCTATTATTATCGGTCGCAGCCAAGCGCTTATGATTGACGCGCAGG
GGGATGAACAAGGACATGCTTGTCACTTCGCGCACAATACTTTATTCATTCCTTATGACGCTCGCCACGTCAATATAGCA
TTGCACCTCCCTGCCATCCAGGAAACGGGCGCGGAGGAACAAAATGATTTTATCCTCGAAATAAATAACCCCGAGGCGCC
TCAGCAACGGCGGGTGACGCACAATGCCGTATTCAGCGATGGGGATATTCATTTTGCCGTTAAGCGAGCCAATGAAGAAT
GGCATCCGGATATCAGCGACTTCAAACAGCCTAACGCGAATCCAACGCCCGTAGGTGATGGCGGCGCCGCCTGGGACAAA
CTGAGAAAGCGCCGGGTCCTGGTGGCGGGCATATTAGCAGTCTTCATGCTCCTTATCGCCTACGTAATCGGTGTTCGTTA
TTATCGCACCTCCCACCAGATTATCTCACTGACTGCGGCCCTTGCTGGTTCCCCTTCGCCGGTAATGTTACTCCAAGGTA
GCGACGGTAAAATTTATGCGCTCGCCAGTCATTATCGCGACCTGCAATGGCTGAATGCCGCCCTGGCCAAACGGCCGAAC
ACCGCGGAGGTTGTGCCGCTTTGGTTAACGCAGACCGCCCAGGACATTACCAGCAGACTGCGTTTGGAGGGTGTACCGGT
ACTGCGATTAGATATGACGCACCCCGCTTCGCCGGTACTGCTGGTGCTGGAGGACATGACGCAGGCCAAGCAAAACGCGT
TGCGAAAAAAGCTATTACCCATGTTGCCCTACGCCAAGACCCTGAATTTCCGTAGCTTTAGCAAAAATTTCCTGGTGCAG
CAGGCCAAGCAAGGTCTTAACAGAATGCACATTGTCTATCGCCAGGTCGCCACACCATTCGGCTTTAGTTTCCTTATCCA
CGATCAGCTGAACGACAATACTATGGCGGAATTGCAGGGTTTCATGGAGATCTATTATTCACAATGGGGAAGTGATTTTA
TCACCTTCTCCATCAATCTTGACGAAAACTGGCTGCGGGACAAGTCCTATCTTGCTGCACCCAACGGCTATGTTTTCGTC
AATCAACATAACTGGTATTTCCCATCAGTTAATGCAACGCAATAA

Upstream 100 bases:

>100_bases
AAAGATCATAAATTTTTGATTTTAAAATGACGTAAACAACATTCCTATTTTCATTTAAGTTCACTATCATCGCGTCTGAA
CTTATTTAGAGATGGAAATA

Downstream 100 bases:

>100_bases
GGACAATACGTATGAGTGACCTCAGAGCCTGGAACGGTAATGGCTGGTTTATCGATGATATCGCCAAAGATTTTGATACC
GGCGCACAAACCATGATGGA

Product: type III secretion apparatus

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSDVFTDNKNEADELIYTLKILFGPMYGSDLILPPNTYSIIIGRSQALMIDAQGDEQGHACHFAHNTLFIPYDARHVNIA
LHLPAIQETGAEEQNDFILEINNPEAPQQRRVTHNAVFSDGDIHFAVKRANEEWHPDISDFKQPNANPTPVGDGGAAWDK
LRKRRVLVAGILAVFMLLIAYVIGVRYYRTSHQIISLTAALAGSPSPVMLLQGSDGKIYALASHYRDLQWLNAALAKRPN
TAEVVPLWLTQTAQDITSRLRLEGVPVLRLDMTHPASPVLLVLEDMTQAKQNALRKKLLPMLPYAKTLNFRSFSKNFLVQ
QAKQGLNRMHIVYRQVATPFGFSFLIHDQLNDNTMAELQGFMEIYYSQWGSDFITFSINLDENWLRDKSYLAAPNGYVFV
NQHNWYFPSVNATQ

Sequences:

>Translated_414_residues
MSDVFTDNKNEADELIYTLKILFGPMYGSDLILPPNTYSIIIGRSQALMIDAQGDEQGHACHFAHNTLFIPYDARHVNIA
LHLPAIQETGAEEQNDFILEINNPEAPQQRRVTHNAVFSDGDIHFAVKRANEEWHPDISDFKQPNANPTPVGDGGAAWDK
LRKRRVLVAGILAVFMLLIAYVIGVRYYRTSHQIISLTAALAGSPSPVMLLQGSDGKIYALASHYRDLQWLNAALAKRPN
TAEVVPLWLTQTAQDITSRLRLEGVPVLRLDMTHPASPVLLVLEDMTQAKQNALRKKLLPMLPYAKTLNFRSFSKNFLVQ
QAKQGLNRMHIVYRQVATPFGFSFLIHDQLNDNTMAELQGFMEIYYSQWGSDFITFSINLDENWLRDKSYLAAPNGYVFV
NQHNWYFPSVNATQ
>Mature_413_residues
SDVFTDNKNEADELIYTLKILFGPMYGSDLILPPNTYSIIIGRSQALMIDAQGDEQGHACHFAHNTLFIPYDARHVNIAL
HLPAIQETGAEEQNDFILEINNPEAPQQRRVTHNAVFSDGDIHFAVKRANEEWHPDISDFKQPNANPTPVGDGGAAWDKL
RKRRVLVAGILAVFMLLIAYVIGVRYYRTSHQIISLTAALAGSPSPVMLLQGSDGKIYALASHYRDLQWLNAALAKRPNT
AEVVPLWLTQTAQDITSRLRLEGVPVLRLDMTHPASPVLLVLEDMTQAKQNALRKKLLPMLPYAKTLNFRSFSKNFLVQQ
AKQGLNRMHIVYRQVATPFGFSFLIHDQLNDNTMAELQGFMEIYYSQWGSDFITFSINLDENWLRDKSYLAAPNGYVFVN
QHNWYFPSVNATQ

Specific function: Required for invasion of epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013387
- InterPro:   IPR019029 [H]

Pfam domain/function: PF09480 PrgH [H]

EC number: NA

Molecular weight: Translated: 46814; Mature: 46683

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVFTDNKNEADELIYTLKILFGPMYGSDLILPPNTYSIIIGRSQALMIDAQGDEQGHA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCEEEEEECCCCCCCCE
CHFAHNTLFIPYDARHVNIALHLPAIQETGAEEQNDFILEINNPEAPQQRRVTHNAVFSD
EEEECCEEEEEECCCEEEEEEEECCHHHCCCCCCCCEEEEECCCCCCHHHCCHHHCEECC
GDIHFAVKRANEEWHPDISDFKQPNANPTPVGDGGAAWDKLRKRRVLVAGILAVFMLLIA
CCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YVIGVRYYRTSHQIISLTAALAGSPSPVMLLQGSDGKIYALASHYRDLQWLNAALAKRPN
HHHHHHHEECCCHHEEEEHHHCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCC
TAEVVPLWLTQTAQDITSRLRLEGVPVLRLDMTHPASPVLLVLEDMTQAKQNALRKKLLP
CCEEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHH
MLPYAKTLNFRSFSKNFLVQQAKQGLNRMHIVYRQVATPFGFSFLIHDQLNDNTMAELQG
HCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
FMEIYYSQWGSDFITFSINLDENWLRDKSYLAAPNGYVFVNQHNWYFPSVNATQ
HHHHHHHHCCCCEEEEEEECCHHHHCCCCEEECCCCEEEEECCCEECCCCCCCC
>Mature Secondary Structure 
SDVFTDNKNEADELIYTLKILFGPMYGSDLILPPNTYSIIIGRSQALMIDAQGDEQGHA
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCEEEEEECCCCCCCCE
CHFAHNTLFIPYDARHVNIALHLPAIQETGAEEQNDFILEINNPEAPQQRRVTHNAVFSD
EEEECCEEEEEECCCEEEEEEEECCHHHCCCCCCCCEEEEECCCCCCHHHCCHHHCEECC
GDIHFAVKRANEEWHPDISDFKQPNANPTPVGDGGAAWDKLRKRRVLVAGILAVFMLLIA
CCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YVIGVRYYRTSHQIISLTAALAGSPSPVMLLQGSDGKIYALASHYRDLQWLNAALAKRPN
HHHHHHHEECCCHHEEEEHHHCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCC
TAEVVPLWLTQTAQDITSRLRLEGVPVLRLDMTHPASPVLLVLEDMTQAKQNALRKKLLP
CCEEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHH
MLPYAKTLNFRSFSKNFLVQQAKQGLNRMHIVYRQVATPFGFSFLIHDQLNDNTMAELQG
HCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
FMEIYYSQWGSDFITFSINLDENWLRDKSYLAAPNGYVFVNQHNWYFPSVNATQ
HHHHHHHHCCCCEEEEEEECCHHHHCCCCEEECCCCEEEEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]