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The map label for this gene is fucP [H]

Identifier: 85058160

GI number: 85058160

Start: 344062

End: 345390

Strand: Reverse

Name: fucP [H]

Synonym: SG0182

Alternate gene names: 85058160

Gene position: 345390-344062 (Counterclockwise)

Preceding gene: 85058162

Following gene: 85058159

Centisome position: 8.28

GC content: 55.76

Gene sequence:

>1329_bases
ATGGGAAATACGCTACTGCCGTCAGAAAAATACCGCGTCACTTCCGGTCCCCGGAACAATAATAACCTTCTCCCCTTCAC
ATTACTCTGCTCATTATTTTTTCTTTGGGCAGTTGCCAACAATCTGAACGACATTTTGCTACCGCAGTTTCAACAGGCAT
TTGATCTTAATAACTTTCAGGCAGGTTTAATTCAATCCTCTTTTTATTTTGGCTATTTTATAATCCCCATACCGGCCGGA
ATATTAATGAAGAAGATTAATTATAAAGCTGGAATAATTACCGGACTGATTTTTTATGCCGCCGGCGCCGCCCTGTTTTG
GCCCGCCGCCCAGACAATGAATTATTCCCTGTTTCTGGCCGGGCTGTTTATTATCGCCGCCGGCCTGGGTTGCCTGGAGA
CCGCCGCCAATCCGTTCGTCACGGTGCTGGGGCCGGAGGAAAGCGGCCATTTTCGCATCAATCTGGCGCAAACCTTCAAC
TCTTTCGGCGCGATTATCGCGGTCGTATTCGGCCAAAGCTTTATTCTGGCCCACGTCCCGCATCAGCCTCCCGAAGTGCT
GGATACCATGACCGCCGAAGCGTTGGCCTGCTATCGCCACAGCCTGGTGATGGCGGTACAAACGCCTTATATGCTGGTCG
TGGCGGTAGTACTGACGGTGGCGCTGCTGATTCTGCTTACCCCTTTTCCTTCCATTCCCAGCGAGAGCGGCGGTGGAAAG
TCCGGCGGCTTCTATTGCGCCGCGCGCCGGCTGCTGGGCTATCGCCACTGGCGCTGGGCGGTGCTGGCCCAATTTTGCTA
TGTCGGGGCGCAAACCGCCTGCTGGAGCTATCTCATCCGCTACGGCGTCGAGGAAGTACCAAATATGACTCCCGGGTTTG
CCGCCAACTATCTGACCGCCACGATGGTGTGTTTCTTTGTCGGACGTTTCAGCGGCACCTGGCTCATACGCCGTTTCGCG
CCACAGGATGTCCTGGCGGTCTGCGCCCTGGCAGCAATGTCGACCTGTCTTATCGCCGCCGCCGGTGGCCATCGCGGTCT
GGTGGCGCTAACACTGTGCAGCCTGTTCATGTCTATCCAGTACCCCACCATTTTTTCGCTTGGCATTCGTCAGCTTGAGC
ACGATACCAAATACGGCGCGTCGATCATCGTGATGACCATCGTCGGTGGCGGCATCGTCACGCCGGTGATGGGTTATGTC
AGCGACGCCGCCGGCGCGATTGCGCCCGCCGAGCTGATCCCCGCGCTGTGCTTCGGCGTGATTTTTTTCTTTGCTCGGTT
CCGCTATGGCGTCAAGCCTGAGGCAGGCGTAGCCACAGCGTCCCATTAA

Upstream 100 bases:

>100_bases
CGTTGATAAGCAGTGTAAGGGGCGCCGGCGTGTCCCGGCCTGAACAGCCAATACCACGACTTTCACTTCATCGCCGCAGT
ACGGGCCAGACGAGGATGAT

Downstream 100 bases:

>100_bases
CCGATTCGTAAAAGGATTTACTATGTCTGAAACGAAAAATCTGCCCAGGGTTGGCATCCGGCCGGTGATCGACGGACGCA
GAATGGGTGTGCGTGAGTCC

Product: L-fucose transporter

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: 6-deoxy-L-galactose permease; L-fucose permease [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MGNTLLPSEKYRVTSGPRNNNNLLPFTLLCSLFFLWAVANNLNDILLPQFQQAFDLNNFQAGLIQSSFYFGYFIIPIPAG
ILMKKINYKAGIITGLIFYAAGAALFWPAAQTMNYSLFLAGLFIIAAGLGCLETAANPFVTVLGPEESGHFRINLAQTFN
SFGAIIAVVFGQSFILAHVPHQPPEVLDTMTAEALACYRHSLVMAVQTPYMLVVAVVLTVALLILLTPFPSIPSESGGGK
SGGFYCAARRLLGYRHWRWAVLAQFCYVGAQTACWSYLIRYGVEEVPNMTPGFAANYLTATMVCFFVGRFSGTWLIRRFA
PQDVLAVCALAAMSTCLIAAAGGHRGLVALTLCSLFMSIQYPTIFSLGIRQLEHDTKYGASIIVMTIVGGGIVTPVMGYV
SDAAGAIAPAELIPALCFGVIFFFARFRYGVKPEAGVATASH

Sequences:

>Translated_442_residues
MGNTLLPSEKYRVTSGPRNNNNLLPFTLLCSLFFLWAVANNLNDILLPQFQQAFDLNNFQAGLIQSSFYFGYFIIPIPAG
ILMKKINYKAGIITGLIFYAAGAALFWPAAQTMNYSLFLAGLFIIAAGLGCLETAANPFVTVLGPEESGHFRINLAQTFN
SFGAIIAVVFGQSFILAHVPHQPPEVLDTMTAEALACYRHSLVMAVQTPYMLVVAVVLTVALLILLTPFPSIPSESGGGK
SGGFYCAARRLLGYRHWRWAVLAQFCYVGAQTACWSYLIRYGVEEVPNMTPGFAANYLTATMVCFFVGRFSGTWLIRRFA
PQDVLAVCALAAMSTCLIAAAGGHRGLVALTLCSLFMSIQYPTIFSLGIRQLEHDTKYGASIIVMTIVGGGIVTPVMGYV
SDAAGAIAPAELIPALCFGVIFFFARFRYGVKPEAGVATASH
>Mature_441_residues
GNTLLPSEKYRVTSGPRNNNNLLPFTLLCSLFFLWAVANNLNDILLPQFQQAFDLNNFQAGLIQSSFYFGYFIIPIPAGI
LMKKINYKAGIITGLIFYAAGAALFWPAAQTMNYSLFLAGLFIIAAGLGCLETAANPFVTVLGPEESGHFRINLAQTFNS
FGAIIAVVFGQSFILAHVPHQPPEVLDTMTAEALACYRHSLVMAVQTPYMLVVAVVLTVALLILLTPFPSIPSESGGGKS
GGFYCAARRLLGYRHWRWAVLAQFCYVGAQTACWSYLIRYGVEEVPNMTPGFAANYLTATMVCFFVGRFSGTWLIRRFAP
QDVLAVCALAAMSTCLIAAAGGHRGLVALTLCSLFMSIQYPTIFSLGIRQLEHDTKYGASIIVMTIVGGGIVTPVMGYVS
DAAGAIAPAELIPALCFGVIFFFARFRYGVKPEAGVATASH

Specific function: Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=432, Percent_Identity=75, Blast_Score=660, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47786; Mature: 47654

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNTLLPSEKYRVTSGPRNNNNLLPFTLLCSLFFLWAVANNLNDILLPQFQQAFDLNNFQ
CCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCH
AGLIQSSFYFGYFIIPIPAGILMKKINYKAGIITGLIFYAAGAALFWPAAQTMNYSLFLA
HHHHHHHHHHEEEEEECCHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHHCCHHHHHH
GLFIIAAGLGCLETAANPFVTVLGPEESGHFRINLAQTFNSFGAIIAVVFGQSFILAHVP
HHHHHHHCCHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECC
HQPPEVLDTMTAEALACYRHSLVMAVQTPYMLVVAVVLTVALLILLTPFPSIPSESGGGK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SGGFYCAARRLLGYRHWRWAVLAQFCYVGAQTACWSYLIRYGVEEVPNMTPGFAANYLTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TMVCFFVGRFSGTWLIRRFAPQDVLAVCALAAMSTCLIAAAGGHRGLVALTLCSLFMSIQ
HHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
YPTIFSLGIRQLEHDTKYGASIIVMTIVGGGIVTPVMGYVSDAAGAIAPAELIPALCFGV
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IFFFARFRYGVKPEAGVATASH
HHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GNTLLPSEKYRVTSGPRNNNNLLPFTLLCSLFFLWAVANNLNDILLPQFQQAFDLNNFQ
CCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCH
AGLIQSSFYFGYFIIPIPAGILMKKINYKAGIITGLIFYAAGAALFWPAAQTMNYSLFLA
HHHHHHHHHHEEEEEECCHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHHCCHHHHHH
GLFIIAAGLGCLETAANPFVTVLGPEESGHFRINLAQTFNSFGAIIAVVFGQSFILAHVP
HHHHHHHCCHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECC
HQPPEVLDTMTAEALACYRHSLVMAVQTPYMLVVAVVLTVALLILLTPFPSIPSESGGGK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SGGFYCAARRLLGYRHWRWAVLAQFCYVGAQTACWSYLIRYGVEEVPNMTPGFAANYLTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TMVCFFVGRFSGTWLIRRFAPQDVLAVCALAAMSTCLIAAAGGHRGLVALTLCSLFMSIQ
HHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
YPTIFSLGIRQLEHDTKYGASIIVMTIVGGGIVTPVMGYVSDAAGAIAPAELIPALCFGV
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IFFFARFRYGVKPEAGVATASH
HHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503; 2553671; 8052131; 2829831; 7783647 [H]