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The map label for this gene is uspA [H]

Identifier: 85058052

GI number: 85058052

Start: 116767

End: 117231

Strand: Reverse

Name: uspA [H]

Synonym: SG0074

Alternate gene names: 85058052

Gene position: 117231-116767 (Counterclockwise)

Preceding gene: 85058053

Following gene: 85058047

Centisome position: 2.81

GC content: 51.83

Gene sequence:

>465_bases
ATGGCTTACAAACACATCCTGATAGCCGTTGACCTTTCACCGGAAAGTAACGTGCTGGTCGAAAAAGCCGTATCGATGGC
CAGACCTTATAACGCCAAAGTTTCCCTGATCCACGTTGACGTCAACTACTCCGACCTCTATACCGGTCTTATCGACGTCA
ATCTCGGCGATATGCAAAAGCGCATATCTGAAGAAACGCAGCATGCGATGACCCAGCTGTCGCAAAACGCTGGCTATCCG
ATTACCGAAACACTGAGCGGCAGCGGCGATCTGGGCCAGGTGCTGGTGGACGCCATTAACAAATACGACGTGGATCTCGT
TTTGTGCGGCCATCACCAGGACTTCTGGAGTAAGTTGATGTCTTCTGCGCGCCAGCTTATCAACACGGTCCATGTGGATA
TGCTCATCGTTCCACTCAGCGATGATGAAGAAGATATGGATGAAATCGCCCCCTGCCCGGCGTGA

Upstream 100 bases:

>100_bases
TGAAAGAGGGATATCAAGACTGGAGACAGTGCGTCCGCTGTCGCCGGGGTCGCATATTGCGACGAGAATAGACAAGTGAC
ATTTTGCAAGGAGTCTGATT

Downstream 100 bases:

>100_bases
AGATATAAAAAGGGGCGAATAAAGGCGCAAAACGCTAGGCAAACATTGGCCTCGTTGGATGGTTTGAAACAGGAAGCCGC
ACTAGCACAAACGGTGGCGG

Product: universal stress protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MAYKHILIAVDLSPESNVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETQHAMTQLSQNAGYP
ITETLSGSGDLGQVLVDAINKYDVDLVLCGHHQDFWSKLMSSARQLINTVHVDMLIVPLSDDEEDMDEIAPCPA

Sequences:

>Translated_154_residues
MAYKHILIAVDLSPESNVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETQHAMTQLSQNAGYP
ITETLSGSGDLGQVLVDAINKYDVDLVLCGHHQDFWSKLMSSARQLINTVHVDMLIVPLSDDEEDMDEIAPCPA
>Mature_153_residues
AYKHILIAVDLSPESNVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETQHAMTQLSQNAGYPI
TETLSGSGDLGQVLVDAINKYDVDLVLCGHHQDFWSKLMSSARQLINTVHVDMLIVPLSDDEEDMDEIAPCPA

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=144, Percent_Identity=93.0555555555556, Blast_Score=277, Evalue=3e-76,
Organism=Escherichia coli, GI1788205, Length=143, Percent_Identity=39.1608391608392, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790358, Length=141, Percent_Identity=34.7517730496454, Blast_Score=100, Evalue=8e-23,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 17016; Mature: 16884

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKHILIAVDLSPESNVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQK
CCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHEEEECCHHHHHH
RISEETQHAMTQLSQNAGYPITETLSGSGDLGQVLVDAINKYDVDLVLCGHHQDFWSKLM
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
SSARQLINTVHVDMLIVPLSDDEEDMDEIAPCPA
HHHHHHHHHHEEEEEEEECCCCHHHHHHCCCCCC
>Mature Secondary Structure 
AYKHILIAVDLSPESNVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQK
CCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHEEEECCHHHHHH
RISEETQHAMTQLSQNAGYPITETLSGSGDLGQVLVDAINKYDVDLVLCGHHQDFWSKLM
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
SSARQLINTVHVDMLIVPLSDDEEDMDEIAPCPA
HHHHHHHHHHEEEEEEEECCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]