| Definition | Xanthomonas oryzae pv. oryzae MAFF 311018, complete genome. |
|---|---|
| Accession | NC_007705 |
| Length | 4,940,217 |
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The map label for this gene is dkgB [H]
Identifier: 84625921
GI number: 84625921
Start: 4819894
End: 4820697
Strand: Reverse
Name: dkgB [H]
Synonym: XOO_4264
Alternate gene names: 84625921
Gene position: 4820697-4819894 (Counterclockwise)
Preceding gene: 84625922
Following gene: 84625920
Centisome position: 97.58
GC content: 61.44
Gene sequence:
>804_bases ATGACTGTCCCCACATTCGGCCTCGGCACCTTTCGCCTTAAAGACCAGGTTGTCATCGACTCAGTGCGTAACGCACTGGA AGTGGGCTATCGCGCAGTCGATACCGCGCAGATCTACGACAACCAAGCGCAGGTCGGCGAAGCGATCGCAGCTTCCGGCA TTGTGCGCGATCAGCTGTACCTGACCACCAAGATCTGGGTCGACAAGTTCGGCGACGGTGCCTTGCTGCCGAGCCTGCAG GAAAGCCTACGCAAACTCGGCACCGCGTATGTGGATCTGACATTGATCCATTGGCCATCGCCGAACGATCAGGTGCCGAT GCGTGAGTATCTGGAAGCGTTGGCGCAGGCCAAACAACAGGGCATGACCCGCGCGATCGGCGTGTCCAACTTCACCATCG CCCTGACCAAGCAGGCGATCGGGATCCTGGGCGCCGACGCCATCGCCACCAACCAGATCGAAGTGCATCCGTATCTGCAG AATCGCGCCTTGACCGACTTCCTGCGCGAACAAGGCATCCATGTCACTTCGTACATGACGTTGGCGGTGGGCGAAGTGCT CAAGTATCCAGTGATCCAGGCGATCGCTGCGCGTCATGCCGCCACCCCGGCCCAGGTCGCCCTGGCTTGGGCATTGCAGC AGGGCCATTCGGTCATCCCCTCTTCGACCAAGCGAGAGAATCTGGAGAGCAACCTCAAGGCGCAGACGCTGCAGCTGAGC GAGCAGGACATGGGCGAGATCGCCGCACTCGACCGTGGGCACCGCCTGGCCAACCCCAAGGCGATCGCGCCCGACTGGGA CTGA
Upstream 100 bases:
>100_bases GGTAAAAACTTCGGAAAGGCCGTCGTCGCCCTCGACTAACCACATGCACTGCGCTCCGCGCACCGCCGCTCCTGCGATTC CCCATTCCCAAAGGAACACA
Downstream 100 bases:
>100_bases GGTCTTGGTTTTGCCATGCGCCGGCATCGCTCGGTGCGTGGCAGCGGCCGCGGCGACGACCGCTCGTCGTCGCGCGCTGG TTGCATGCGCCGGCCGCTGC
Product: 2,5-diketo-D-gluconate reductase B
Products: NA
Alternate protein names: 2,5-DKG reductase B; 2,5-DKGR B; 25DKGR-B; AKR5D [H]
Number of amino acids: Translated: 267; Mature: 266
Protein sequence:
>267_residues MTVPTFGLGTFRLKDQVVIDSVRNALEVGYRAVDTAQIYDNQAQVGEAIAASGIVRDQLYLTTKIWVDKFGDGALLPSLQ ESLRKLGTAYVDLTLIHWPSPNDQVPMREYLEALAQAKQQGMTRAIGVSNFTIALTKQAIGILGADAIATNQIEVHPYLQ NRALTDFLREQGIHVTSYMTLAVGEVLKYPVIQAIAARHAATPAQVALAWALQQGHSVIPSSTKRENLESNLKAQTLQLS EQDMGEIAALDRGHRLANPKAIAPDWD
Sequences:
>Translated_267_residues MTVPTFGLGTFRLKDQVVIDSVRNALEVGYRAVDTAQIYDNQAQVGEAIAASGIVRDQLYLTTKIWVDKFGDGALLPSLQ ESLRKLGTAYVDLTLIHWPSPNDQVPMREYLEALAQAKQQGMTRAIGVSNFTIALTKQAIGILGADAIATNQIEVHPYLQ NRALTDFLREQGIHVTSYMTLAVGEVLKYPVIQAIAARHAATPAQVALAWALQQGHSVIPSSTKRENLESNLKAQTLQLS EQDMGEIAALDRGHRLANPKAIAPDWD >Mature_266_residues TVPTFGLGTFRLKDQVVIDSVRNALEVGYRAVDTAQIYDNQAQVGEAIAASGIVRDQLYLTTKIWVDKFGDGALLPSLQE SLRKLGTAYVDLTLIHWPSPNDQVPMREYLEALAQAKQQGMTRAIGVSNFTIALTKQAIGILGADAIATNQIEVHPYLQN RALTDFLREQGIHVTSYMTLAVGEVLKYPVIQAIAARHAATPAQVALAWALQQGHSVIPSSTKRENLESNLKAQTLQLSE QDMGEIAALDRGHRLANPKAIAPDWD
Specific function: Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI310109922, Length=272, Percent_Identity=30.5147058823529, Blast_Score=145, Evalue=4e-35, Organism=Homo sapiens, GI310109920, Length=289, Percent_Identity=30.1038062283737, Blast_Score=143, Evalue=1e-34, Organism=Homo sapiens, GI45446745, Length=289, Percent_Identity=30.1038062283737, Blast_Score=143, Evalue=1e-34, Organism=Homo sapiens, GI4503285, Length=289, Percent_Identity=30.1038062283737, Blast_Score=143, Evalue=1e-34, Organism=Homo sapiens, GI5453543, Length=292, Percent_Identity=30.1369863013699, Blast_Score=142, Evalue=2e-34, Organism=Homo sapiens, GI24497585, Length=292, Percent_Identity=29.7945205479452, Blast_Score=142, Evalue=2e-34, Organism=Homo sapiens, GI223468663, Length=288, Percent_Identity=29.8611111111111, Blast_Score=142, Evalue=5e-34, Organism=Homo sapiens, GI24497583, Length=300, Percent_Identity=30.3333333333333, Blast_Score=139, Evalue=2e-33, Organism=Homo sapiens, GI24497577, Length=291, Percent_Identity=29.8969072164948, Blast_Score=138, Evalue=6e-33, Organism=Homo sapiens, GI5174391, Length=291, Percent_Identity=29.8969072164948, Blast_Score=138, Evalue=6e-33, Organism=Homo sapiens, GI4502049, Length=287, Percent_Identity=31.7073170731707, Blast_Score=132, Evalue=2e-31, Organism=Homo sapiens, GI291291012, Length=278, Percent_Identity=29.136690647482, Blast_Score=132, Evalue=3e-31, Organism=Homo sapiens, GI93277124, Length=300, Percent_Identity=28.3333333333333, Blast_Score=132, Evalue=4e-31, Organism=Homo sapiens, GI5174695, Length=295, Percent_Identity=28.8135593220339, Blast_Score=127, Evalue=8e-30, Organism=Homo sapiens, GI300116273, Length=272, Percent_Identity=28.6764705882353, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI310109924, Length=154, Percent_Identity=30.5194805194805, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI310109926, Length=104, Percent_Identity=33.6538461538462, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI207028673, Length=104, Percent_Identity=33.6538461538462, Blast_Score=72, Evalue=3e-13, Organism=Escherichia coli, GI1786400, Length=267, Percent_Identity=64.0449438202247, Blast_Score=362, Evalue=1e-101, Organism=Escherichia coli, GI87082198, Length=263, Percent_Identity=36.5019011406844, Blast_Score=164, Evalue=5e-42, Organism=Escherichia coli, GI1788081, Length=272, Percent_Identity=29.0441176470588, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1787674, Length=259, Percent_Identity=27.027027027027, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1788070, Length=319, Percent_Identity=26.6457680250784, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI48994888, Length=273, Percent_Identity=26.7399267399267, Blast_Score=69, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17550248, Length=284, Percent_Identity=31.6901408450704, Blast_Score=140, Evalue=5e-34, Organism=Caenorhabditis elegans, GI17537075, Length=290, Percent_Identity=32.0689655172414, Blast_Score=138, Evalue=3e-33, Organism=Caenorhabditis elegans, GI17561298, Length=267, Percent_Identity=31.8352059925094, Blast_Score=137, Evalue=6e-33, Organism=Caenorhabditis elegans, GI17552492, Length=281, Percent_Identity=28.4697508896797, Blast_Score=135, Evalue=3e-32, Organism=Caenorhabditis elegans, GI17537077, Length=289, Percent_Identity=30.7958477508651, Blast_Score=133, Evalue=7e-32, Organism=Caenorhabditis elegans, GI71998625, Length=261, Percent_Identity=30.2681992337165, Blast_Score=128, Evalue=3e-30, Organism=Caenorhabditis elegans, GI17561300, Length=263, Percent_Identity=30.4182509505703, Blast_Score=128, Evalue=3e-30, Organism=Caenorhabditis elegans, GI17537079, Length=294, Percent_Identity=28.9115646258503, Blast_Score=127, Evalue=7e-30, Organism=Caenorhabditis elegans, GI17566692, Length=284, Percent_Identity=28.8732394366197, Blast_Score=117, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17538386, Length=265, Percent_Identity=28.6792452830189, Blast_Score=117, Evalue=7e-27, Organism=Caenorhabditis elegans, GI17564128, Length=291, Percent_Identity=27.8350515463918, Blast_Score=116, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17562292, Length=270, Percent_Identity=29.6296296296296, Blast_Score=108, Evalue=4e-24, Organism=Saccharomyces cerevisiae, GI6324694, Length=292, Percent_Identity=32.1917808219178, Blast_Score=159, Evalue=4e-40, Organism=Saccharomyces cerevisiae, GI6320576, Length=281, Percent_Identity=35.5871886120996, Blast_Score=156, Evalue=3e-39, Organism=Saccharomyces cerevisiae, GI6321896, Length=306, Percent_Identity=28.4313725490196, Blast_Score=127, Evalue=2e-30, Organism=Saccharomyces cerevisiae, GI6322556, Length=280, Percent_Identity=27.8571428571429, Blast_Score=120, Evalue=3e-28, Organism=Saccharomyces cerevisiae, GI6319625, Length=291, Percent_Identity=29.8969072164948, Blast_Score=109, Evalue=5e-25, Organism=Saccharomyces cerevisiae, GI6320079, Length=259, Percent_Identity=25.4826254826255, Blast_Score=82, Evalue=1e-16, Organism=Drosophila melanogaster, GI24662789, Length=294, Percent_Identity=31.6326530612245, Blast_Score=145, Evalue=2e-35, Organism=Drosophila melanogaster, GI24644950, Length=297, Percent_Identity=30.6397306397306, Blast_Score=139, Evalue=2e-33, Organism=Drosophila melanogaster, GI221378297, Length=317, Percent_Identity=29.3375394321767, Blast_Score=134, Evalue=8e-32, Organism=Drosophila melanogaster, GI20129731, Length=278, Percent_Identity=30.9352517985612, Blast_Score=127, Evalue=6e-30, Organism=Drosophila melanogaster, GI24657054, Length=286, Percent_Identity=30.4195804195804, Blast_Score=127, Evalue=1e-29, Organism=Drosophila melanogaster, GI24663317, Length=288, Percent_Identity=29.8611111111111, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI24662785, Length=290, Percent_Identity=30.6896551724138, Blast_Score=117, Evalue=5e-27, Organism=Drosophila melanogaster, GI21356425, Length=286, Percent_Identity=28.6713286713287, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI24662781, Length=289, Percent_Identity=30.7958477508651, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI45553081, Length=284, Percent_Identity=28.5211267605634, Blast_Score=111, Evalue=4e-25, Organism=Drosophila melanogaster, GI281366140, Length=259, Percent_Identity=27.027027027027, Blast_Score=92, Evalue=3e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.274 [H]
Molecular weight: Translated: 29182; Mature: 29050
Theoretical pI: Translated: 6.25; Mature: 6.25
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTVPTFGLGTFRLKDQVVIDSVRNALEVGYRAVDTAQIYDNQAQVGEAIAASGIVRDQLY CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHE LTTKIWVDKFGDGALLPSLQESLRKLGTAYVDLTLIHWPSPNDQVPMREYLEALAQAKQQ EEHEEHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHC GMTRAIGVSNFTIALTKQAIGILGADAIATNQIEVHPYLQNRALTDFLREQGIHVTSYMT CCHHEECCCCEEEEEHHHHHHHHCCCCEECCEEEECHHHHHHHHHHHHHHCCCCHHHHHH LAVGEVLKYPVIQAIAARHAATPAQVALAWALQQGHSVIPSSTKRENLESNLKAQTLQLS HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC EQDMGEIAALDRGHRLANPKAIAPDWD HHHHHHHHHHCCCCCCCCCCCCCCCCC >Mature Secondary Structure TVPTFGLGTFRLKDQVVIDSVRNALEVGYRAVDTAQIYDNQAQVGEAIAASGIVRDQLY CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHE LTTKIWVDKFGDGALLPSLQESLRKLGTAYVDLTLIHWPSPNDQVPMREYLEALAQAKQQ EEHEEHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHC GMTRAIGVSNFTIALTKQAIGILGADAIATNQIEVHPYLQNRALTDFLREQGIHVTSYMT CCHHEECCCCEEEEEHHHHHHHHCCCCEECCEEEECHHHHHHHHHHHHHHCCCCHHHHHH LAVGEVLKYPVIQAIAARHAATPAQVALAWALQQGHSVIPSSTKRENLESNLKAQTLQLS HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC EQDMGEIAALDRGHRLANPKAIAPDWD HHHHHHHHHHCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796; 11108008 [H]