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The map label for this gene is adhP [C]

Identifier: 84625889

GI number: 84625889

Start: 4783764

End: 4784351

Strand: Reverse

Name: adhP [C]

Synonym: XOO_4232

Alternate gene names: 84625889

Gene position: 4784351-4783764 (Counterclockwise)

Preceding gene: 84625890

Following gene: 84625888

Centisome position: 96.84

GC content: 66.33

Gene sequence:

>588_bases
TTGAAAGCATTCCAGATTGGCAATCAAACCGGCCTCGAGAGCCTGGTCGTGGCCGAGATGTTCGAGCCAGTCGCAGGGCC
GGGTCAGGTCATCGTCGCGCCGCGACTGGTTGGCCTGATCAACCGCGACCTGCAGATCCTGAAAGGCACCTACGCCGGCA
AGCTCGTCGAAACGCGCGTTCCCGTTGCCGAAGGCGTGGGCATCGTGACCTCCGTCGGTGCAGGCGTCAGCGACGTCGCG
CCGGGCGACCGTGTCGTCAGCGGGCACTTCCCCGCCTGGCTGGACGGCAGGTTCCGCGCCGAGATGTTCGCCCACGATCT
GGGCGTGACCCACGATGGCTGGCTGGCGGAAACGGTGGTGCTGCCTGCATCCGCGCTGATCAAGGTGCCCGTGTCGTTGG
ACGACCAAGATGTCGCGGCGCTGGCATCGGCCGCAGTCACCGCCTGGCACGCCGGAAGTCGCCAGGATCAAGGCCGGCGA
CCTAGTGCTCTGTCTGGGAACCGTCGGCGTCTCGATGGCCGCGCTCGAACTCGCCAAGCGCCACGGTGCCCATGTCGCCA
TCACCTCATCCAGCGACGAGAAGCTTGA

Upstream 100 bases:

>100_bases
ACCCAGCGCTGCGCTGAGTCATCGCGACGATGGCGTCGAATGCGCCATCCCCGACGACGCCAGCCACGTTCGGCCGGCGT
CTCAGTACAGGCAGTCCCCC

Downstream 100 bases:

>100_bases
ACTCGCGCGCCGCCTGGGCGCCGACATCACCGTCACCTATCGCACCGATCCCGACTGGGCCGATGCCGTGACGCAGCTGT
CCGGCGGCGGCGCGGACGTC

Product: hypothetical protein

Products: Glycerol; Nicotinamide adenine dinucleotide [C]

Alternate protein names: Alcohol Dehydrogenase Zinc-Containing; Zinc-Containing Alcohol Dehydrogenase Superfamily Protein; Zinc-Containing Alcohol Dehydrogenase; Zinc-Containing Alcohol Dehydrogenase Superfamily; NADPHQuinone Reductase; Alcohol Dehydrogenase GroES Domain Protein; Zn-Dependent Alcohol Dehydrogenase; Alcohol Dehydrogenase Protein

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKAFQIGNQTGLESLVVAEMFEPVAGPGQVIVAPRLVGLINRDLQILKGTYAGKLVETRVPVAEGVGIVTSVGAGVSDVA
PGDRVVSGHFPAWLDGRFRAEMFAHDLGVTHDGWLAETVVLPASALIKVPVSLDDQDVAALASAAVTAWHAGSRQDQGRR
PSALSGNRRRLDGRARTRQAPRCPCRHHLIQRREA

Sequences:

>Translated_195_residues
MKAFQIGNQTGLESLVVAEMFEPVAGPGQVIVAPRLVGLINRDLQILKGTYAGKLVETRVPVAEGVGIVTSVGAGVSDVA
PGDRVVSGHFPAWLDGRFRAEMFAHDLGVTHDGWLAETVVLPASALIKVPVSLDDQDVAALASAAVTAWHAGSRQDQGRR
PSALSGNRRRLDGRARTRQAPRCPCRHHLIQRREA
>Mature_195_residues
MKAFQIGNQTGLESLVVAEMFEPVAGPGQVIVAPRLVGLINRDLQILKGTYAGKLVETRVPVAEGVGIVTSVGAGVSDVA
PGDRVVSGHFPAWLDGRFRAEMFAHDLGVTHDGWLAETVVLPASALIKVPVSLDDQDVAALASAAVTAWHAGSRQDQGRR
PSALSGNRRRLDGRARTRQAPRCPCRHHLIQRREA

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.1 [C]

Molecular weight: Translated: 20835; Mature: 20835

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFQIGNQTGLESLVVAEMFEPVAGPGQVIVAPRLVGLINRDLQILKGTYAGKLVETRV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHCCC
PVAEGVGIVTSVGAGVSDVAPGDRVVSGHFPAWLDGRFRAEMFAHDLGVTHDGWLAETVV
CHHHCCCHHHHCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
LPASALIKVPVSLDDQDVAALASAAVTAWHAGSRQDQGRRPSALSGNRRRLDGRARTRQA
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
PRCPCRHHLIQRREA
CCCCHHHHHHHHCCC
>Mature Secondary Structure
MKAFQIGNQTGLESLVVAEMFEPVAGPGQVIVAPRLVGLINRDLQILKGTYAGKLVETRV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHCCC
PVAEGVGIVTSVGAGVSDVAPGDRVVSGHFPAWLDGRFRAEMFAHDLGVTHDGWLAETVV
CHHHCCCHHHHCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
LPASALIKVPVSLDDQDVAALASAAVTAWHAGSRQDQGRRPSALSGNRRRLDGRARTRQA
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
PRCPCRHHLIQRREA
CCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+; NADH [C]

Metal ions: Co2+ Zn2+-depleted [C]

Kcat value (1/min): 150 [C]

Specific activity: 19

Km value (mM): 0.2 {tryptophol}} 0.0074 {NAD+}} 0.0069 {NAD+}} 13 {ethylene} 6 {methanol}} 27 {pentanol}} 0.44 {1-butanol}} 120 {ethanol}} 0.91 {acetaldehyde}} 0.1 {acetaldehyde}} 0.005 {1-octanol}} 0.004 {benzyl} 0.005 {cyclohe

Substrates: D-Glyceraldehyde; H+; Nicotinamide adenine dinucleotide - reduced [C]

Specific reaction: D-Glyceraldehyde + H+ + Nicotinamide adenine dinucleotide - reduced <==> Glycerol + Nicotinamide adenine dinucleotide [C]

General reaction: Redox reaction [C]

Inhibitor: 2, 2'-Bipyridyl; 4-Methyl pyrazole acetaldehyde; 8-Amino-6-methoxyquinoline; 8-Hydroxy quinoline-5-sulfonic acid; Acetaldehyde; Dipicolinic acid; EDTA; Ethanol; GSH; Heptafluorbutanol; Imidazole; Iodoacetamide; Iodoacetate; Isobutyramide EDTA; NAD+; NADH;

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA