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The map label for this gene is acs [C]

Identifier: 84625731

GI number: 84625731

Start: 4596386

End: 4597891

Strand: Reverse

Name: acs [C]

Synonym: XOO_4074

Alternate gene names: 84625731

Gene position: 4597891-4596386 (Counterclockwise)

Preceding gene: 84625736

Following gene: 84625730

Centisome position: 93.07

GC content: 67.53

Gene sequence:

>1506_bases
ATGATTTGCCGTGCCGCACAACGCGCACGCCGCCTACACACATGTGCAAGCCATCGACACAAGACGCGCTCGCCGCGGTT
TGCCGCAGAGGGAACTTCCCGACTTGCCAGCAGCGCGGGTGGCGGACAAGCTAGCGTGCTCTTGCGACCGACGGTTTTCA
TGTCCAGCCTGCCTGCTCCCCCTATTTCCCATCCGATGGCTGTTGGTGCGCTCGACCGGCCGCTGGCCTGGCGCGCGGGG
CAGTCGGTCGATCTGGCCACCTTCATCGCGCATGTGCACGGTCTGGCGCAGCAGCTGCCTGAAGGTAGCCATGCAGTGAA
TTTGTGCGAGGACCGCTACCGTTTCATGGTGGCGTTCTACGCGTGCGCGCTGCGCGGGCAGGTATCGCTGCTGCCATCGT
CGCGTGCACCTGCGGTAGTGGGCGAAGTGCAGGCGCGCCACGCCGATGCGTACTGCCTGGGCGATCTGGACCTGGAGCTC
GCGCCGCCGCGGTATTGGCAGCTGCCTGCCGAATTGCCGCAGGCTGCGGGCCCGATTCCACAGTTGGCCGACGACGCGCT
GGTGGCGATCGGTTTCACCTCGGGCACCACCGGCAGCCCGCAACCCAATCCCAAGACCTGGGGCAGTTTCCTGACCAGCA
CGCGCCAGGATCTGGTCGCGCTGGAAAGCCTGTGGGCGCACACCGACGCTGTGCCGCACGTGGTCGCCACGGTGCCGCCG
CAGCACATGTATGGCATGGAGTTGTCGGTGCTGCTGCCGATGGTGACCACCCTGGCAGTGCACGCCGAGCGCCCGTTCTT
CCCGGACGATGTGGCGCGTGCGCTGGCCGATATTCCCGCGCCGCGTGTCTTGGTGACCACGCCCGTGCATCTGCGTGCGT
TGGTCGAATCCGGCGTGGCACTGCCGCCGCTGGCCGGCATCGTGTCGGCCACTGCACCGATGGCGCCGGAAATCGCCGCT
GCGGCCGAAGCGCGTTTCGGTGGTGAAGTGCGCGAGATGTTCGGCTCCACCGAAACCTGCGTGTTCGCCGTGCGTCGCAC
GGCGCTGGAAGCGGCATGGACGCCTTTGCCCGGTGTGCGCCTGGAAACGCAGGCCGCAGGCACGCTGGTGCATGCGCCGC
ATCTGGCCACACCGGTGCTGCTGGCCGACATGATGGACGTGGCCGACGACGGCCGTTTTCAGGTACGCGGCCGTCAAGCC
GATCTGCTGGAAATTGCCGGAAAACGCGCATCGCTGGCCGATCTCACCCGGCGCCTGCTCGCCATTCCCGGTGTGGTCGA
TGGCACCATCGTGCAACTCGCGCCCGACTCCGGCCAGGCGGTCGGCCGCATCGCCGCGCTGGTGGTCGCTCCCTCCCTGG
ACGAAGCCCAGGTGCTGGCCGCACTGCGCGTCAGCGTAGACCCGGTGTTCCTGCCGCGCCGTCTGCGCAAGGTCGCCGCA
TTGCCACGCAACGAAACCGGCAAACTGCCGCGCGATGTGGTGCTGGGCTTGCTCAAGGGTGAGTGA

Upstream 100 bases:

>100_bases
TGGAGACTGCCCCAGCGACTGATCGTAAGCTGGCGAAACCGTTGTTCCGAGGTTTCCTGGGCGCTGCCACGCCGGTGGAG
TATCTCCGACCGGCGAGCAG

Downstream 100 bases:

>100_bases
GGCTGGGTAAGCCCGTCTGCAGCTCGCTCACGCCGGCCAGATGAGAGCGGACGGCTCACTGGTCAAGCGCTGGATGCGCG
CAGAGTTAGGCCGTGGGGAG

Product: AMP-ligase

Products: Acetyl-CoA; AMP; Diphosphate [C]

Alternate protein names: CoA Ligase; AMP-Ligase; Acyl-Co A Synthetase/AMP-(Fatty) Acid Ligase; Acyl-Co A Synthetase; AMP-(Fatty) Acid Ligase; Acyl-Co A Synthetases/AMP-(Fatty) Acid Ligases-Like Protein; Peptide Synthase; Acyl-Co A Synthetase/AMP-(Fatty) Acid Ligase Related Enzyme; Amp-Dependent Synthetase Or Ligase Protein; Amp-Dependent Synthetase And Ligase Family Protein; Surfactin Synthetase; Acyl-CoA Synthetase; Aconitate Hydratase; 4-Coumarate-CoA Ligase; Fatty Acid Degradation; Acyl-Co A Synthetase/AMP-(Fatty) Acid Ligase-Like; AMP-(Fatty)Acid Ligases; Fatty Acid CoA Ligase; Acetyl-Co A Synthetase

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MICRAAQRARRLHTCASHRHKTRSPRFAAEGTSRLASSAGGGQASVLLRPTVFMSSLPAPPISHPMAVGALDRPLAWRAG
QSVDLATFIAHVHGLAQQLPEGSHAVNLCEDRYRFMVAFYACALRGQVSLLPSSRAPAVVGEVQARHADAYCLGDLDLEL
APPRYWQLPAELPQAAGPIPQLADDALVAIGFTSGTTGSPQPNPKTWGSFLTSTRQDLVALESLWAHTDAVPHVVATVPP
QHMYGMELSVLLPMVTTLAVHAERPFFPDDVARALADIPAPRVLVTTPVHLRALVESGVALPPLAGIVSATAPMAPEIAA
AAEARFGGEVREMFGSTETCVFAVRRTALEAAWTPLPGVRLETQAAGTLVHAPHLATPVLLADMMDVADDGRFQVRGRQA
DLLEIAGKRASLADLTRRLLAIPGVVDGTIVQLAPDSGQAVGRIAALVVAPSLDEAQVLAALRVSVDPVFLPRRLRKVAA
LPRNETGKLPRDVVLGLLKGE

Sequences:

>Translated_501_residues
MICRAAQRARRLHTCASHRHKTRSPRFAAEGTSRLASSAGGGQASVLLRPTVFMSSLPAPPISHPMAVGALDRPLAWRAG
QSVDLATFIAHVHGLAQQLPEGSHAVNLCEDRYRFMVAFYACALRGQVSLLPSSRAPAVVGEVQARHADAYCLGDLDLEL
APPRYWQLPAELPQAAGPIPQLADDALVAIGFTSGTTGSPQPNPKTWGSFLTSTRQDLVALESLWAHTDAVPHVVATVPP
QHMYGMELSVLLPMVTTLAVHAERPFFPDDVARALADIPAPRVLVTTPVHLRALVESGVALPPLAGIVSATAPMAPEIAA
AAEARFGGEVREMFGSTETCVFAVRRTALEAAWTPLPGVRLETQAAGTLVHAPHLATPVLLADMMDVADDGRFQVRGRQA
DLLEIAGKRASLADLTRRLLAIPGVVDGTIVQLAPDSGQAVGRIAALVVAPSLDEAQVLAALRVSVDPVFLPRRLRKVAA
LPRNETGKLPRDVVLGLLKGE
>Mature_501_residues
MICRAAQRARRLHTCASHRHKTRSPRFAAEGTSRLASSAGGGQASVLLRPTVFMSSLPAPPISHPMAVGALDRPLAWRAG
QSVDLATFIAHVHGLAQQLPEGSHAVNLCEDRYRFMVAFYACALRGQVSLLPSSRAPAVVGEVQARHADAYCLGDLDLEL
APPRYWQLPAELPQAAGPIPQLADDALVAIGFTSGTTGSPQPNPKTWGSFLTSTRQDLVALESLWAHTDAVPHVVATVPP
QHMYGMELSVLLPMVTTLAVHAERPFFPDDVARALADIPAPRVLVTTPVHLRALVESGVALPPLAGIVSATAPMAPEIAA
AAEARFGGEVREMFGSTETCVFAVRRTALEAAWTPLPGVRLETQAAGTLVHAPHLATPVLLADMMDVADDGRFQVRGRQA
DLLEIAGKRASLADLTRRLLAIPGVVDGTIVQLAPDSGQAVGRIAALVVAPSLDEAQVLAALRVSVDPVFLPRRLRKVAA
LPRNETGKLPRDVVLGLLKGE

Specific function: Enables The Cell To Use Acetate During Aerobic Growth To Generate Energy Via The Tca Cycle, And Biosynthetic Compounds Via The Glyoxylate Shunt. Acetylates Chey, The Response Regulator Involved In Flagellar Movement And Chemotaxis. [C]

COG id: COG0365

COG function: function code I; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.2.1.1 [C]

Molecular weight: Translated: 53144; Mature: 53144

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICRAAQRARRLHTCASHRHKTRSPRFAAEGTSRLASSAGGGQASVLLRPTVFMSSLPAP
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECHHHHHCCCCC
PISHPMAVGALDRPLAWRAGQSVDLATFIAHVHGLAQQLPEGSHAVNLCEDRYRFMVAFY
CCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ACALRGQVSLLPSSRAPAVVGEVQARHADAYCLGDLDLELAPPRYWQLPAELPQAAGPIP
HHHHCCCEEECCCCCCCHHHHHHHHHCCCEEEEECCCCEECCCHHCCCCHHHHHHCCCCC
QLADDALVAIGFTSGTTGSPQPNPKTWGSFLTSTRQDLVALESLWAHTDAVPHVVATVPP
CCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QHMYGMELSVLLPMVTTLAVHAERPFFPDDVARALADIPAPRVLVTTPVHLRALVESGVA
HHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCC
LPPLAGIVSATAPMAPEIAAAAEARFGGEVREMFGSTETCVFAVRRTALEAAWTPLPGVR
CCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCE
LETQAAGTLVHAPHLATPVLLADMMDVADDGRFQVRGRQADLLEIAGKRASLADLTRRLL
EECCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHH
AIPGVVDGTIVQLAPDSGQAVGRIAALVVAPSLDEAQVLAALRVSVDPVFLPRRLRKVAA
HCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHC
LPRNETGKLPRDVVLGLLKGE
CCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MICRAAQRARRLHTCASHRHKTRSPRFAAEGTSRLASSAGGGQASVLLRPTVFMSSLPAP
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECHHHHHCCCCC
PISHPMAVGALDRPLAWRAGQSVDLATFIAHVHGLAQQLPEGSHAVNLCEDRYRFMVAFY
CCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ACALRGQVSLLPSSRAPAVVGEVQARHADAYCLGDLDLELAPPRYWQLPAELPQAAGPIP
HHHHCCCEEECCCCCCCHHHHHHHHHCCCEEEEECCCCEECCCHHCCCCHHHHHHCCCCC
QLADDALVAIGFTSGTTGSPQPNPKTWGSFLTSTRQDLVALESLWAHTDAVPHVVATVPP
CCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QHMYGMELSVLLPMVTTLAVHAERPFFPDDVARALADIPAPRVLVTTPVHLRALVESGVA
HHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCC
LPPLAGIVSATAPMAPEIAAAAEARFGGEVREMFGSTETCVFAVRRTALEAAWTPLPGVR
CCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCE
LETQAAGTLVHAPHLATPVLLADMMDVADDGRFQVRGRQADLLEIAGKRASLADLTRRLL
EECCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHH
AIPGVVDGTIVQLAPDSGQAVGRIAALVVAPSLDEAQVLAALRVSVDPVFLPRRLRKVAA
HCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHC
LPRNETGKLPRDVVLGLLKGE
CCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetate; ATP; Coenzyme A [C]

Specific reaction: Acetate + ATP + Coenzyme A --> Acetyl-CoA + AMP + Diphosphate [C]

General reaction: Acid-thiol ligation [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA