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The map label for this gene is trpD [H]

Identifier: 84625593

GI number: 84625593

Start: 4434472

End: 4435509

Strand: Reverse

Name: trpD [H]

Synonym: XOO_3936

Alternate gene names: 84625593

Gene position: 4435509-4434472 (Counterclockwise)

Preceding gene: 84625594

Following gene: 84625592

Centisome position: 89.78

GC content: 65.9

Gene sequence:

>1038_bases
ATGCCCATCACTCCGCAAGAAGCCCTGCAACGCACCATCGAGCATCGCGAAATCTTCCACGACGAAATGGTCGGGTTGAT
GCGGCAGATCATGCGCGGCGAGGTCTCCGACATGATGGTTGCCGCGATCCTCACCGGGCTGCGGGTCAAGAAGGAAACCA
TCGGCGAAATCGCCGGTGCGGCCACGGTGATGCGCGAGTTCTCGCGCCGTGTGGACGTGAGCGATCACCAGCACATGGTC
GACATTGTCGGCACCGGCGGCGATGGCTCGCACACATTCAATATCTCCACCTGCGCGATGTTCGTCGCCGCAGCCGGTGG
TGCCAAGGTGGCCAAGCACGGCAATCGCAGCGTCTCATCTAAATCCGGTAGCGCCGACGCGCTGGAAGCGTTGGGCGCGG
TGATCGAGCTGCAGCCCGAGCAGGTTGCCGATGCACTGGCGCAAACCGGCATCGGTTTCATGTATGCGCCGTTGCATCAC
CCGTCCATGAAGGTGGTGGCGCCGGTGCGTCGGGAAATGGGTGTACGCACCATCTTCAACATCCTCGGCCCGCTCACCAA
CCCGGCCGGCTCGCCGAATATCCTGATGGGCGTGTTTCACCCCGACCTAGTCGGCATCCAGGCGCGCGTGCTGCAGGAGC
TCGGCGCCGAGCGTGCGTTGGTGGTGTGGGGGCGCGACGGCATGGACGAACTCTCGCTCGGCGCTGGCACACTGGTCGGC
GAATTGCGCGATGGCCAGGTACGCGAATACGAAGTGCATCCGGAAGATTTCGGCATCGCCATGTCGGCCAGCCGCAACCT
CAAGGTCGCCGATGCTGCGCAATCGCGCGCGATGCTGCTGCGGGTGCTGGACAACGTGCCCGGCCCCGCGCTGGACATCG
TGGCGCTCAACGCCGGTGCCGCGTTGTACGTGGCCGGCCTGGCCGGCAGCATTGCCGATGGCGTGCTGCGCGCACGCGCG
GTACTCGCCGACGGCTCGGCGCGCGCGCGGCTGGACGCCTATGTCGCCTACACCCACCAGCTCGCCGGGCAGCCCTGA

Upstream 100 bases:

>100_bases
TCGCCTGGTGCATCGCTTGGCGCCCGCGCGCTCCCATGCTGATCCAGCGCGCCGCAAGCCGCCTGCGTCTCCATCCATCA
CGTTCTGCCACGGTTGTCCC

Downstream 100 bases:

>100_bases
GTCATGCCGGCGCCGCAACGCTGCGTCAATCACCCGCCGGCATCCGCACAGTGACGCTGGCATGCTGCGCGGCATGCAGC
TGCCCTCCAGTGCGGTTATC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MPITPQEALQRTIEHREIFHDEMVGLMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGAATVMREFSRRVDVSDHQHMV
DIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSSKSGSADALEALGAVIELQPEQVADALAQTGIGFMYAPLHH
PSMKVVAPVRREMGVRTIFNILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVG
ELRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLRVLDNVPGPALDIVALNAGAALYVAGLAGSIADGVLRARA
VLADGSARARLDAYVAYTHQLAGQP

Sequences:

>Translated_345_residues
MPITPQEALQRTIEHREIFHDEMVGLMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGAATVMREFSRRVDVSDHQHMV
DIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSSKSGSADALEALGAVIELQPEQVADALAQTGIGFMYAPLHH
PSMKVVAPVRREMGVRTIFNILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVG
ELRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLRVLDNVPGPALDIVALNAGAALYVAGLAGSIADGVLRARA
VLADGSARARLDAYVAYTHQLAGQP
>Mature_344_residues
PITPQEALQRTIEHREIFHDEMVGLMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGAATVMREFSRRVDVSDHQHMVD
IVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSSKSGSADALEALGAVIELQPEQVADALAQTGIGFMYAPLHHP
SMKVVAPVRREMGVRTIFNILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVGE
LRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLRVLDNVPGPALDIVALNAGAALYVAGLAGSIADGVLRARAV
LADGSARARLDAYVAYTHQLAGQP

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=280, Percent_Identity=42.8571428571429, Blast_Score=199, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6320561, Length=325, Percent_Identity=29.2307692307692, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36509; Mature: 36377

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITPQEALQRTIEHREIFHDEMVGLMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVMREFSRRVDVSDHQHMVDIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSS
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHCCCCHHHHCCCCCCCC
KSGSADALEALGAVIELQPEQVADALAQTGIGFMYAPLHHPSMKVVAPVRREMGVRTIFN
CCCCHHHHHHHHHHHEECHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
ILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVG
HHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCHHHEE
ELRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLRVLDNVPGPALDIVALNAGA
CCCCCCEEEEEECCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
ALYVAGLAGSIADGVLRARAVLADGSARARLDAYVAYTHQLAGQP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PITPQEALQRTIEHREIFHDEMVGLMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVMREFSRRVDVSDHQHMVDIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSS
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHCCCCHHHHCCCCCCCC
KSGSADALEALGAVIELQPEQVADALAQTGIGFMYAPLHHPSMKVVAPVRREMGVRTIFN
CCCCHHHHHHHHHHHEECHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
ILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVG
HHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCHHHEE
ELRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLRVLDNVPGPALDIVALNAGA
CCCCCCEEEEEECCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
ALYVAGLAGSIADGVLRARAVLADGSARARLDAYVAYTHQLAGQP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]