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The map label for this gene is grx [H]

Identifier: 84625118

GI number: 84625118

Start: 3917514

End: 3917882

Strand: Reverse

Name: grx [H]

Synonym: XOO_3461

Alternate gene names: 84625118

Gene position: 3917882-3917514 (Counterclockwise)

Preceding gene: 84625127

Following gene: 84625117

Centisome position: 79.31

GC content: 63.41

Gene sequence:

>369_bases
ATGGAAATTCCAGTCGCCCGGTACCATGTGTCAGACCCCATACCAACCACGGAGTTTCCCGTGAGCCAAGACCATACCGA
TCAGGGCGCGGCCTCCGGTCCGCAGATCACCCTGTATTCCTCGGCCATTTGCCCGTATTGCGTGGCAGCCAAGAACTTCC
TCAAGAGCAAGGGCAAGACCTGGACCGAGGTGCGGATCGACCTGGATCCGGCCGAGCGCGACAAGATGGTCGCCCTGGCC
AAGCGCACCAGCGTGCCGCAGATCTTCGTCGGCGACGTCCATGTGGGCGGCTACGACGACATGATGGCCATGCACCGGGC
CGGCAAGCTCGAGCAGTTGTTGGCCGGCAGCGCGGGCGGTCAGGCATGA

Upstream 100 bases:

>100_bases
AGCAGGCGCAAGTGGAACTCCCAGGTAGTTCGCGGAGCATGCGGGCAGCACGGCGCGACGGCGTGAATCATCGGTTAACC
CGCAGTGTTGCGGTGAGGAC

Downstream 100 bases:

>100_bases
GTGGTTCCGACGAAGGCAGCGCCGACCGCCTGCGCGAATTCACCGAATTCCGTCAGCGCATGAATCAGCGCATCCTGGCC
GAGCCGAACCAAGTGGTGCG

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MEIPVARYHVSDPIPTTEFPVSQDHTDQGAASGPQITLYSSAICPYCVAAKNFLKSKGKTWTEVRIDLDPAERDKMVALA
KRTSVPQIFVGDVHVGGYDDMMAMHRAGKLEQLLAGSAGGQA

Sequences:

>Translated_122_residues
MEIPVARYHVSDPIPTTEFPVSQDHTDQGAASGPQITLYSSAICPYCVAAKNFLKSKGKTWTEVRIDLDPAERDKMVALA
KRTSVPQIFVGDVHVGGYDDMMAMHRAGKLEQLLAGSAGGQA
>Mature_122_residues
MEIPVARYHVSDPIPTTEFPVSQDHTDQGAASGPQITLYSSAICPYCVAAKNFLKSKGKTWTEVRIDLDPAERDKMVALA
KRTSVPQIFVGDVHVGGYDDMMAMHRAGKLEQLLAGSAGGQA

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=80, Percent_Identity=42.5, Blast_Score=75, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 13161; Mature: 13161

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIPVARYHVSDPIPTTEFPVSQDHTDQGAASGPQITLYSSAICPYCVAAKNFLKSKGKT
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCE
WTEVRIDLDPAERDKMVALAKRTSVPQIFVGDVHVGGYDDMMAMHRAGKLEQLLAGSAGG
EEEEEEECCCCCCCCEEHHHHHCCCCEEEECCEEECCHHHHHHHHHCCCHHHHHHCCCCC
QA
CC
>Mature Secondary Structure
MEIPVARYHVSDPIPTTEFPVSQDHTDQGAASGPQITLYSSAICPYCVAAKNFLKSKGKT
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCE
WTEVRIDLDPAERDKMVALAKRTSVPQIFVGDVHVGGYDDMMAMHRAGKLEQLLAGSAGG
EEEEEEECCCCCCCCEEHHHHHCCCCEEEECCEEECCHHHHHHHHHCCCHHHHHHCCCCC
QA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]