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The map label for this gene is ilvE [H]

Identifier: 84625082

GI number: 84625082

Start: 3884973

End: 3886058

Strand: Reverse

Name: ilvE [H]

Synonym: XOO_3425

Alternate gene names: 84625082

Gene position: 3886058-3884973 (Counterclockwise)

Preceding gene: 84625083

Following gene: 84625081

Centisome position: 78.66

GC content: 65.47

Gene sequence:

>1086_bases
GTGTCCGTGTCCTTCGCTTCCACCCGTTCTCCGTCGCCGCGCAGCGCCGACGAATTGTCCGTGATCCTGGCCGCGCCCGG
TTTCGGGCTGCATTTCACCGACCACATGGTCGCCATCTCCTGGAACAACGAGCAGGGTTGGCATGACGCGCAGGTGCGCG
CCTACGGCCCGCTGCAGCTGGATCCGGCGGCGTCGGTGTTGCATTACGGCCAGGAGATCTTCGAAGGCATCAAGGCCTAT
CGGCATGCCGACGGCTCGATCTGGACCTTCCGTCCGCAGGCCAATGGCGAGCGCTTGCAGCGCTCGGCACGCCGTCTGGC
ACTGCCGGAATTGCCGGTGGATCTGTTCGTCGAATCGCTGCGTCAGTTGGTCGCCGTGGACGGCAATTGGGTACCGTCGG
CGCCGGAAACCAGCCTGTATTTCCGCCCGTTCATGATTGCCGATGAGGCCTTTCTGGGGGTGCGTGCGGCGCACAAGGCG
TCGTACTACGTGATCGCCAGCCCGGCGGGCCCGTACTTCGCCAACGGCGTGGCGCCGGTGTCGATCTGGCTGTCCACCGA
GTATGCACGTGCGGCCAAGGGCGGTACCGGTGCGGCCAAGTGCGGCGGCAATTACGCCGCCTCGTTGCTGCCGCAGCAGA
AGGCCTACGCGCAGGGCTGCTCGCAGGTGCTGTTCCTGGACCCGGTGGAAGGCAAATACATCGAGGAACTGGGCGGCATG
AACGTGTTCCTGGTCTACAGGGACGGCACGTTGGTGACCCCGGAACTGTCCGGCAGCATCCTTGAAGGCATCACCCGCGA
CAGCATCCTGCAACTTGCCCGCGACCGCGGCATGCAGGTGATCGAGCGCAAGGTCGCCATCGACGAGTGGAAGCAGGGCG
TGGCGTCGGGCGAAATCACCGAGGTGTTCGCCTGCGGCACGGCGGCGGTGGTGACCCCGATCGGCGAGTTGAAGGGCGAT
GGCTTTGCGGTAGGCGATCTGTCCGTGCCGGCTGGCGAGGTGACCATGTCGCTGCGTCAGGAACTGACCGACATCCAGTA
CGGGCGCGTGCCGGACCGTCATGGCTGGCTGGTGCGTTTGTCGTAA

Upstream 100 bases:

>100_bases
TCCGAAGCGGCCCGTCTCGAGACTGGCATGCTCTGATCGTCACGCGCCATGTCCACGATGTGGCGCCGCGTCCTTTCGCC
CGCCATACAGGAATCCCCCG

Downstream 100 bases:

>100_bases
GTCGATATATTTCGTCAAACAAGCGCCTCCGTGTGTCAGCACGGGGGCTTTTTTGTTTGCGGAACAGCAGAAAATACGTT
TTTCGACCGGGAACCCGTCG

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSVSFASTRSPSPRSADELSVILAAPGFGLHFTDHMVAISWNNEQGWHDAQVRAYGPLQLDPAASVLHYGQEIFEGIKAY
RHADGSIWTFRPQANGERLQRSARRLALPELPVDLFVESLRQLVAVDGNWVPSAPETSLYFRPFMIADEAFLGVRAAHKA
SYYVIASPAGPYFANGVAPVSIWLSTEYARAAKGGTGAAKCGGNYAASLLPQQKAYAQGCSQVLFLDPVEGKYIEELGGM
NVFLVYRDGTLVTPELSGSILEGITRDSILQLARDRGMQVIERKVAIDEWKQGVASGEITEVFACGTAAVVTPIGELKGD
GFAVGDLSVPAGEVTMSLRQELTDIQYGRVPDRHGWLVRLS

Sequences:

>Translated_361_residues
MSVSFASTRSPSPRSADELSVILAAPGFGLHFTDHMVAISWNNEQGWHDAQVRAYGPLQLDPAASVLHYGQEIFEGIKAY
RHADGSIWTFRPQANGERLQRSARRLALPELPVDLFVESLRQLVAVDGNWVPSAPETSLYFRPFMIADEAFLGVRAAHKA
SYYVIASPAGPYFANGVAPVSIWLSTEYARAAKGGTGAAKCGGNYAASLLPQQKAYAQGCSQVLFLDPVEGKYIEELGGM
NVFLVYRDGTLVTPELSGSILEGITRDSILQLARDRGMQVIERKVAIDEWKQGVASGEITEVFACGTAAVVTPIGELKGD
GFAVGDLSVPAGEVTMSLRQELTDIQYGRVPDRHGWLVRLS
>Mature_360_residues
SVSFASTRSPSPRSADELSVILAAPGFGLHFTDHMVAISWNNEQGWHDAQVRAYGPLQLDPAASVLHYGQEIFEGIKAYR
HADGSIWTFRPQANGERLQRSARRLALPELPVDLFVESLRQLVAVDGNWVPSAPETSLYFRPFMIADEAFLGVRAAHKAS
YYVIASPAGPYFANGVAPVSIWLSTEYARAAKGGTGAAKCGGNYAASLLPQQKAYAQGCSQVLFLDPVEGKYIEELGGMN
VFLVYRDGTLVTPELSGSILEGITRDSILQLARDRGMQVIERKVAIDEWKQGVASGEITEVFACGTAAVVTPIGELKGDG
FAVGDLSVPAGEVTMSLRQELTDIQYGRVPDRHGWLVRLS

Specific function: Catalyzes the reversible transfers of an amino group from glutamate to the alpha-ketoacid of the respective amino acid in the final step in the biosynthesis of branchedchain amino acids. The amino acids can be ranked in the following order with respect to

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI296010904, Length=341, Percent_Identity=41.6422287390029, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI296010906, Length=341, Percent_Identity=41.6422287390029, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI38176287, Length=341, Percent_Identity=41.6422287390029, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI50658084, Length=331, Percent_Identity=39.5770392749245, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI296010902, Length=341, Percent_Identity=36.6568914956012, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI296010900, Length=341, Percent_Identity=36.6568914956012, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI258614015, Length=287, Percent_Identity=39.0243902439024, Blast_Score=192, Evalue=3e-49,
Organism=Escherichia coli, GI48994963, Length=320, Percent_Identity=32.1875, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17568601, Length=343, Percent_Identity=37.9008746355685, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17565728, Length=343, Percent_Identity=35.5685131195335, Blast_Score=195, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6322002, Length=362, Percent_Identity=41.9889502762431, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6322608, Length=342, Percent_Identity=40.9356725146199, Blast_Score=231, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24641779, Length=367, Percent_Identity=40.3269754768392, Blast_Score=232, Evalue=2e-61,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005786 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 39119; Mature: 38988

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSFASTRSPSPRSADELSVILAAPGFGLHFTDHMVAISWNNEQGWHDAQVRAYGPLQL
CCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCEEEEEEECCCCCCCCCEEEEECCEEE
DPAASVLHYGQEIFEGIKAYRHADGSIWTFRPQANGERLQRSARRLALPELPVDLFVESL
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
RQLVAVDGNWVPSAPETSLYFRPFMIADEAFLGVRAAHKASYYVIASPAGPYFANGVAPV
HHHHCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHCCCCEEEEECCCCCHHHCCCCEE
SIWLSTEYARAAKGGTGAAKCGGNYAASLLPQQKAYAQGCSQVLFLDPVEGKYIEELGGM
EEEEECHHHHHHCCCCCCHHCCCCHHHHHCCHHHHHHHCCCEEEEECCCCCHHHHHHCCC
NVFLVYRDGTLVTPELSGSILEGITRDSILQLARDRGMQVIERKVAIDEWKQGVASGEIT
EEEEEEECCEEECCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHH
EVFACGTAAVVTPIGELKGDGFAVGDLSVPAGEVTMSLRQELTDIQYGRVPDRHGWLVRL
EEEECCCHHEECCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
S
C
>Mature Secondary Structure 
SVSFASTRSPSPRSADELSVILAAPGFGLHFTDHMVAISWNNEQGWHDAQVRAYGPLQL
CCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCEEEEEEECCCCCCCCCEEEEECCEEE
DPAASVLHYGQEIFEGIKAYRHADGSIWTFRPQANGERLQRSARRLALPELPVDLFVESL
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
RQLVAVDGNWVPSAPETSLYFRPFMIADEAFLGVRAAHKASYYVIASPAGPYFANGVAPV
HHHHCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHCCCCEEEEECCCCCHHHCCCCEE
SIWLSTEYARAAKGGTGAAKCGGNYAASLLPQQKAYAQGCSQVLFLDPVEGKYIEELGGM
EEEEECHHHHHHCCCCCCHHCCCCHHHHHCCHHHHHHHCCCEEEEECCCCCHHHHHHCCC
NVFLVYRDGTLVTPELSGSILEGITRDSILQLARDRGMQVIERKVAIDEWKQGVASGEIT
EEEEEEECCEEECCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHH
EVFACGTAAVVTPIGELKGDGFAVGDLSVPAGEVTMSLRQELTDIQYGRVPDRHGWLVRL
EEEECCCHHEECCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA