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The map label for this gene is ipk [H]

Identifier: 84625063

GI number: 84625063

Start: 3866762

End: 3867631

Strand: Reverse

Name: ipk [H]

Synonym: XOO_3406

Alternate gene names: 84625063

Gene position: 3867631-3866762 (Counterclockwise)

Preceding gene: 84625064

Following gene: 84625062

Centisome position: 78.29

GC content: 66.44

Gene sequence:

>870_bases
ATGAACGCGCCGGGCACTGATTGGTCGGCGTGGCCTGCGCCGGCCAAGCTCAATCTGTTCCTGCAGATCACCGGGCGCCG
CGCCGATGGCTATCACCTGCTGCAGACCGTGTTCCGGCTGCTGGATTGGGGGGACACCATTCATCTTCGCGTGCGCAGCG
ACGGCCAGATCCTGCGCATTGGCGAGAGTTTGCCCGGCGTGGCCGAAGACGATGACCTGGTGATCCGCGCCGCGCGCCTG
CTGCAATCGGCGGCCGGCGCTGCGGCGGGCGCGGAGATTCGGGTCGACAAGCGCATCCCGGCAGGTGGCGGTTTCGGCGG
TGGATCGTCGGACGCGGCGACTGTGTTGGTGGCGCTCAATGCCTTGTGGGGCCTGGCTTTGACGGCGGATACGCTGGCCG
AATTGGGTCTGCAGCTGGGTGCGGATGTGCCGGTTTTCGTGCGCGGTCGCAATGCCTGGGCCGAAGGCGTGGGCGAACAG
CTGACCCCGATTGCCCTCCCGGAAGCGGCCTATCTGCTGGTCGATCCGGGCGTTCACGTGCCGACACCGGTGTTATTTCG
ATCACAGGAATTGACGCGGGATGCCGCGCCCGCGAAAATAACTGACTTCGCTTCCGGTTCTCTGCTCGACAATGCGTTCG
AGCCGGTTCTGCGGCGCCGCGAACCTGCCGTCGAGGCAGTGTTCCAGGCGCTTTCCAGGGTCGGCACACCGCGATTGACC
GGGTCGGGAAGTGGCTGTTTCGTCGAATTCGCCACGCGCGCTGCTGCAGAGCAGGCCCTGGCGCAGTTGCCGGGCAGTCT
GCGGGCGTGGGTGGTGGAGGGTGCAGCGCACTCCCCTCTGCTCGACGCACGGGACGCGATGAAGGTTTGA

Upstream 100 bases:

>100_bases
CGGCCAGCGCCGACCAGCCCGAGCTTCCGCAGCGGATCGAAGCCCGTTACGGTGAGGCCAAGGTCCGTCTGCTGGTCGAT
CAGTGGACCGTATCGCCCTG

Downstream 100 bases:

>100_bases
TGCAGGGGCGTCGCCAAGAGGCCCAAGGCACCAGGTTTTGATCCTGGCATTCGTAGGTTCGAATCCTACCGCCCCTGCCA
ATATGCAGATCCCTCTGCAA

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNAPGTDWSAWPAPAKLNLFLQITGRRADGYHLLQTVFRLLDWGDTIHLRVRSDGQILRIGESLPGVAEDDDLVIRAARL
LQSAAGAAAGAEIRVDKRIPAGGGFGGGSSDAATVLVALNALWGLALTADTLAELGLQLGADVPVFVRGRNAWAEGVGEQ
LTPIALPEAAYLLVDPGVHVPTPVLFRSQELTRDAAPAKITDFASGSLLDNAFEPVLRRREPAVEAVFQALSRVGTPRLT
GSGSGCFVEFATRAAAEQALAQLPGSLRAWVVEGAAHSPLLDARDAMKV

Sequences:

>Translated_289_residues
MNAPGTDWSAWPAPAKLNLFLQITGRRADGYHLLQTVFRLLDWGDTIHLRVRSDGQILRIGESLPGVAEDDDLVIRAARL
LQSAAGAAAGAEIRVDKRIPAGGGFGGGSSDAATVLVALNALWGLALTADTLAELGLQLGADVPVFVRGRNAWAEGVGEQ
LTPIALPEAAYLLVDPGVHVPTPVLFRSQELTRDAAPAKITDFASGSLLDNAFEPVLRRREPAVEAVFQALSRVGTPRLT
GSGSGCFVEFATRAAAEQALAQLPGSLRAWVVEGAAHSPLLDARDAMKV
>Mature_289_residues
MNAPGTDWSAWPAPAKLNLFLQITGRRADGYHLLQTVFRLLDWGDTIHLRVRSDGQILRIGESLPGVAEDDDLVIRAARL
LQSAAGAAAGAEIRVDKRIPAGGGFGGGSSDAATVLVALNALWGLALTADTLAELGLQLGADVPVFVRGRNAWAEGVGEQ
LTPIALPEAAYLLVDPGVHVPTPVLFRSQELTRDAAPAKITDFASGSLLDNAFEPVLRRREPAVEAVFQALSRVGTPRLT
GSGSGCFVEFATRAAAEQALAQLPGSLRAWVVEGAAHSPLLDARDAMKV

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=278, Percent_Identity=51.7985611510791, Blast_Score=251, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 30407; Mature: 30407

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPGTDWSAWPAPAKLNLFLQITGRRADGYHLLQTVFRLLDWGDTIHLRVRSDGQILRI
CCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
GESLPGVAEDDDLVIRAARLLQSAAGAAAGAEIRVDKRIPAGGGFGGGSSDAATVLVALN
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHH
ALWGLALTADTLAELGLQLGADVPVFVRGRNAWAEGVGEQLTPIALPEAAYLLVDPGVHV
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCCCEECCCCEEEEECCCCCC
PTPVLFRSQELTRDAAPAKITDFASGSLLDNAFEPVLRRREPAVEAVFQALSRVGTPRLT
CCCCEECCHHHHHCCCCCEEHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
GSGSGCFVEFATRAAAEQALAQLPGSLRAWVVEGAAHSPLLDARDAMKV
CCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHCC
>Mature Secondary Structure
MNAPGTDWSAWPAPAKLNLFLQITGRRADGYHLLQTVFRLLDWGDTIHLRVRSDGQILRI
CCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
GESLPGVAEDDDLVIRAARLLQSAAGAAAGAEIRVDKRIPAGGGFGGGSSDAATVLVALN
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHH
ALWGLALTADTLAELGLQLGADVPVFVRGRNAWAEGVGEQLTPIALPEAAYLLVDPGVHV
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCCCEECCCCEEEEECCCCCC
PTPVLFRSQELTRDAAPAKITDFASGSLLDNAFEPVLRRREPAVEAVFQALSRVGTPRLT
CCCCEECCHHHHHCCCCCEEHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
GSGSGCFVEFATRAAAEQALAQLPGSLRAWVVEGAAHSPLLDARDAMKV
CCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]