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The map label for this gene is irlR [H]

Identifier: 84624998

GI number: 84624998

Start: 3802182

End: 3802898

Strand: Reverse

Name: irlR [H]

Synonym: XOO_3341

Alternate gene names: 84624998

Gene position: 3802898-3802182 (Counterclockwise)

Preceding gene: 84625003

Following gene: 84624997

Centisome position: 76.98

GC content: 66.95

Gene sequence:

>717_bases
ATGCGGCTGCTGGTCATTGAAGACAACCGCAATATGGTTGCCAACCTGTTCGACTACTTCGAAGCGCGCGGGTATACCCT
GGACGCTGCGCCCGACGGCATCACCGGCCTGCACCTGGCCACCACCCACCACTACGACGCCCTGATCCTTGACTGGATGA
TGCCGCGCATGGATGGGCCGGAAGTGCTGCGCCGGCTGCGCGAACAGCACCAATCCGAGCTGCCGGTGATCATGCTCACC
GCGCGCGACGAACTGCCGGACAAGATCGCCGGCTTCCGCGCCGGCGCCGACGACTACCTGACCAAACCCTTTGCACTGCC
CGAGCTGGAAGTGCGTATCGAAGCCTTGCTGGCCCGCGCGCATGGCCGTCGTCGCGGCAAGCTGCTGCAAGTGGCCGACC
TGCGGCTGGACCTGGCCACCCTGGAGGCCACCCGCGCCGGCCAGGTGCTGCATCTGTATCCGGCGTGCCGCAAGTTGCTC
GAAGTGCTGATGCAGGCCAGCCCGGCGGCGGTGACGCGGCAACGCCTGGAGCAGTCGCTGTGGGACGACGACCCGCCCGA
CGGCGACATGCTGCGCTCGCATATCTACGAGCTACGCCGCAGCGTGGACGGCCCGTTCGCAGAAAAACTGATCCACACCT
TGCCGCGACTCGGCTACCGGCTGGCGCAGCTGTATGCGGCCGAGGCGCCTGGCGCGGGCGACAGCAGCGATGTCTAA

Upstream 100 bases:

>100_bases
CAACCGATGGGAAGGCCGTACCGGCGATACCGGCCGTGTTTGGTTGGCCTCGGTTAGGATGCGCACACCGTGCCTGCTGG
GCCGCCCCGGAACCCCGCTC

Downstream 100 bases:

>100_bases
ACAGCGCCCCTTGGGTCTCCGCGTGCTGGTGTGGTTGTTCGGCTACACGCTGTTGATGACGCTGGCGGTGTTCGGCACTG
CGCAGTACCTGCACGAACGC

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRLLVIEDNRNMVANLFDYFEARGYTLDAAPDGITGLHLATTHHYDALILDWMMPRMDGPEVLRRLREQHQSELPVIMLT
ARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARAHGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLL
EVLMQASPAAVTRQRLEQSLWDDDPPDGDMLRSHIYELRRSVDGPFAEKLIHTLPRLGYRLAQLYAAEAPGAGDSSDV

Sequences:

>Translated_238_residues
MRLLVIEDNRNMVANLFDYFEARGYTLDAAPDGITGLHLATTHHYDALILDWMMPRMDGPEVLRRLREQHQSELPVIMLT
ARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARAHGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLL
EVLMQASPAAVTRQRLEQSLWDDDPPDGDMLRSHIYELRRSVDGPFAEKLIHTLPRLGYRLAQLYAAEAPGAGDSSDV
>Mature_238_residues
MRLLVIEDNRNMVANLFDYFEARGYTLDAAPDGITGLHLATTHHYDALILDWMMPRMDGPEVLRRLREQHQSELPVIMLT
ARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARAHGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLL
EVLMQASPAAVTRQRLEQSLWDDDPPDGDMLRSHIYELRRSVDGPFAEKLIHTLPRLGYRLAQLYAAEAPGAGDSSDV

Specific function: Member of the two-component regulatory system irlR/irlS. May be involved in invasion of eukaryotic cells and heavy-metal resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=34.2342342342342, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=37.3333333333333, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=35.4260089686099, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=35.8744394618834, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=28.7610619469027, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=29.9107142857143, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=32, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=34.4497607655502, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=30.2631578947368, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=36.283185840708, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790860, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=37.9310344827586, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790863, Length=118, Percent_Identity=37.2881355932203, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787229, Length=180, Percent_Identity=29.4444444444444, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=32.2314049586777, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26857; Mature: 26857

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLVIEDNRNMVANLFDYFEARGYTLDAAPDGITGLHLATTHHYDALILDWMMPRMDGP
CEEEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCCH
EVLRRLREQHQSELPVIMLTARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARA
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
HGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLLEVLMQASPAAVTRQRLEQSL
HCHHCCCEEEHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
WDDDPPDGDMLRSHIYELRRSVDGPFAEKLIHTLPRLGYRLAQLYAAEAPGAGDSSDV
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRLLVIEDNRNMVANLFDYFEARGYTLDAAPDGITGLHLATTHHYDALILDWMMPRMDGP
CEEEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCCH
EVLRRLREQHQSELPVIMLTARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARA
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
HGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLLEVLMQASPAAVTRQRLEQSL
HCHHCCCEEEHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
WDDDPPDGDMLRSHIYELRRSVDGPFAEKLIHTLPRLGYRLAQLYAAEAPGAGDSSDV
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9393784 [H]