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The map label for this gene is holA [H]

Identifier: 84624797

GI number: 84624797

Start: 3561061

End: 3562089

Strand: Reverse

Name: holA [H]

Synonym: XOO_3140

Alternate gene names: 84624797

Gene position: 3562089-3561061 (Counterclockwise)

Preceding gene: 84624798

Following gene: 84624796

Centisome position: 72.1

GC content: 68.22

Gene sequence:

>1029_bases
ATGGAACTTCGCCCCGAGCAACTGGCCGGCCAGTCCAACCAGCCGTTGCAGCCAGTCTATCTGATCGCCGGCCCGGAGAC
CTTGCGTGTGCTTGAGGCCGCCGACGCTGTGCGCGCGCGCGCGCGCGCTGAAGGCATCGGTGAACGCGAAGTCTTCGATG
CCGATGGCCGCGATTTCGACTGGAATCAGCTCGACGCCAGCTTCAACGCGCCCAGCCTGTTCAGTCCGCGCCGCCTGGTC
GAGGTGCGCCTGCCCAGCGGCAAGCCCGGCAAGGATGGCGCCGAGGTCATCACCCGCTTCTGCGCCAACCCGCCGCCGGA
CGTGGTGCTGCTGATCACCGCCAACGACTGGAGCAAGGCGCATCAGGGCAAGTGGGCCGAGGCCGTCGGCCGCATCGGCA
CGATTGCCGTTGCCTGGGCGATCAAGCCGCATGAACTCTCCGACTGGATCGAGCGTCGCCTGCGTGCGCACGGCCTGCGT
GCCGACGCCGCCGCGGTGCAGCGCCTGAGCGAGCGGGTGGAAGGCAACCTGCTTGCCGCTGCGCAGGAAATCGACAAGCT
CGCTCTGCTGGCCGATGGCAAGACACTGGATCTGCAGGCGATGGAGTCGTTGGTGGCCGATGCCGCACGCTACGACGTCT
TTCGGCTGGCCGAAACCACGTTTTCGGGGCAGCCGGCCGCGGTGATCCGCATGCTTGCCGGCCTGCGCGCCGAAGGCGAG
GCGGTCGCCGCGCTGATGCCGATCCTCATCAAGGAATTACTTCGCACTGCGTCGCTGGCGAAGGTGCAGGCCAACGGCGG
CAACCTCGCTGCCGAAATGAAGGCGCAGGGGCTGTGGGAATCGCGCCAGGCGCCATTCAAGCGCGCGCTGCAACGTCACC
CCGAACCGCGTCGCTGGGAGCGCTTCGTCGCCGAAGCCGGGCTGGTCGATCGCATGGCCAAAGGTCGCGCCGACGGCGAC
GCCTGGGTGGGTCTGGAACGCCTGCTGGTGGCCGTGGCCGAAGCCCGCGCGGTGAGATTGTTGGCGTGA

Upstream 100 bases:

>100_bases
GCCCCGGTGCAGCCCACAACACCGCCCGAATCCAGCGTGCCGGCTGCGCTGCCGCCCGCGCCGACCTCGGGCAACTAAGC
CGCGCCCGCTCTTTTCCGCT

Downstream 100 bases:

>100_bases
CCGCGAGGGAGGCCGGAACCGCGGAGCAGGGCGCAGGCTCAGGAGAGCGGGAGTTGCCGACTAGCGCAACCGCAGACCCA
AGCACACAGCCGGCATTCCT

Product: DNA polymerase III subunit delta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MELRPEQLAGQSNQPLQPVYLIAGPETLRVLEAADAVRARARAEGIGEREVFDADGRDFDWNQLDASFNAPSLFSPRRLV
EVRLPSGKPGKDGAEVITRFCANPPPDVVLLITANDWSKAHQGKWAEAVGRIGTIAVAWAIKPHELSDWIERRLRAHGLR
ADAAAVQRLSERVEGNLLAAAQEIDKLALLADGKTLDLQAMESLVADAARYDVFRLAETTFSGQPAAVIRMLAGLRAEGE
AVAALMPILIKELLRTASLAKVQANGGNLAAEMKAQGLWESRQAPFKRALQRHPEPRRWERFVAEAGLVDRMAKGRADGD
AWVGLERLLVAVAEARAVRLLA

Sequences:

>Translated_342_residues
MELRPEQLAGQSNQPLQPVYLIAGPETLRVLEAADAVRARARAEGIGEREVFDADGRDFDWNQLDASFNAPSLFSPRRLV
EVRLPSGKPGKDGAEVITRFCANPPPDVVLLITANDWSKAHQGKWAEAVGRIGTIAVAWAIKPHELSDWIERRLRAHGLR
ADAAAVQRLSERVEGNLLAAAQEIDKLALLADGKTLDLQAMESLVADAARYDVFRLAETTFSGQPAAVIRMLAGLRAEGE
AVAALMPILIKELLRTASLAKVQANGGNLAAEMKAQGLWESRQAPFKRALQRHPEPRRWERFVAEAGLVDRMAKGRADGD
AWVGLERLLVAVAEARAVRLLA
>Mature_342_residues
MELRPEQLAGQSNQPLQPVYLIAGPETLRVLEAADAVRARARAEGIGEREVFDADGRDFDWNQLDASFNAPSLFSPRRLV
EVRLPSGKPGKDGAEVITRFCANPPPDVVLLITANDWSKAHQGKWAEAVGRIGTIAVAWAIKPHELSDWIERRLRAHGLR
ADAAAVQRLSERVEGNLLAAAQEIDKLALLADGKTLDLQAMESLVADAARYDVFRLAETTFSGQPAAVIRMLAGLRAEGE
AVAALMPILIKELLRTASLAKVQANGGNLAAEMKAQGLWESRQAPFKRALQRHPEPRRWERFVAEAGLVDRMAKGRADGD
AWVGLERLLVAVAEARAVRLLA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the b

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786859, Length=294, Percent_Identity=32.312925170068, Blast_Score=110, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37341; Mature: 37341

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRPEQLAGQSNQPLQPVYLIAGPETLRVLEAADAVRARARAEGIGEREVFDADGRDFD
CCCCCHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCC
WNQLDASFNAPSLFSPRRLVEVRLPSGKPGKDGAEVITRFCANPPPDVVLLITANDWSKA
HHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHH
HQGKWAEAVGRIGTIAVAWAIKPHELSDWIERRLRAHGLRADAAAVQRLSERVEGNLLAA
HCCCHHHHHCCHHEEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHH
AQEIDKLALLADGKTLDLQAMESLVADAARYDVFRLAETTFSGQPAAVIRMLAGLRAEGE
HHHHHHHHEEECCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCH
AVAALMPILIKELLRTASLAKVQANGGNLAAEMKAQGLWESRQAPFKRALQRHPEPRRWE
HHHHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHCCHHHCCCHHHHHHHCCCCHHHHH
RFVAEAGLVDRMAKGRADGDAWVGLERLLVAVAEARAVRLLA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELRPEQLAGQSNQPLQPVYLIAGPETLRVLEAADAVRARARAEGIGEREVFDADGRDFD
CCCCCHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCC
WNQLDASFNAPSLFSPRRLVEVRLPSGKPGKDGAEVITRFCANPPPDVVLLITANDWSKA
HHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHH
HQGKWAEAVGRIGTIAVAWAIKPHELSDWIERRLRAHGLRADAAAVQRLSERVEGNLLAA
HCCCHHHHHCCHHEEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHH
AQEIDKLALLADGKTLDLQAMESLVADAARYDVFRLAETTFSGQPAAVIRMLAGLRAEGE
HHHHHHHHEEECCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCH
AVAALMPILIKELLRTASLAKVQANGGNLAAEMKAQGLWESRQAPFKRALQRHPEPRRWE
HHHHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHCCHHHCCCHHHHHHHCCCCHHHHH
RFVAEAGLVDRMAKGRADGDAWVGLERLLVAVAEARAVRLLA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8505303; 1400251; 8905232; 9278503; 3316191; 8505304; 1575709 [H]