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The map label for this gene is fbp [H]

Identifier: 84624590

GI number: 84624590

Start: 3316948

End: 3317379

Strand: Direct

Name: fbp [H]

Synonym: XOO_2933

Alternate gene names: 84624590

Gene position: 3316948-3317379 (Clockwise)

Preceding gene: 84624583

Following gene: 84624591

Centisome position: 67.14

GC content: 65.74

Gene sequence:

>432_bases
ATGCGCCTTCTGTTGACGCTCTGTGTCGCCCTGCTGCTCGCAGGCTGCGCGCCCGCCCTGCCGCCCTCCGGTGGCACCAT
CGCCAGCTTCGAGCGGATCGACCGCACGGTGGGGACCGGCGCAGAAGCCACACCAGGGGCGATGGTCACCGTGCACTACA
CCGGCTGGCTATACGACGAAAACGCCGCCGACAAACACGGCAAGAAGTTCGACAGCTCGCTGGATCGCGCCGAGCCGTTC
CAGTTTGTGCTGGGTGGCCATCAGGTCATCCGCGGCTGGGACGATGGCGTTGCCGGCATGCGTGTCGGCGGCAAGCGCAC
CTTGATGATTCCGCCCGATTACGGTTACGGCGATAACGGCGCCGGTGGTGTGATTCCGCCCGGTGCCTCGTTGGTCTTCG
ATGTGGAATTGCTGGACGTGCAGCCGCGCTGA

Upstream 100 bases:

>100_bases
TTCGTCGGGAACATTGCGCAGATTGAGCAGCAGCTTGGCCATGGCGCGATGATAACGGGGGCCAGGTGCGATAATGCCGC
CTTTCTTCACGGACCCTGCC

Downstream 100 bases:

>100_bases
GTGCCAGAACGATGACGGGTTCGAACAAGCGGCGGCTGGCCGTGATCGGTGGTGGGCCGGCCGGCTTGATGGCGGCAGAA
GTGGCCTGTGCTGCGGGCCT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MRLLLTLCVALLLAGCAPALPPSGGTIASFERIDRTVGTGAEATPGAMVTVHYTGWLYDENAADKHGKKFDSSLDRAEPF
QFVLGGHQVIRGWDDGVAGMRVGGKRTLMIPPDYGYGDNGAGGVIPPGASLVFDVELLDVQPR

Sequences:

>Translated_143_residues
MRLLLTLCVALLLAGCAPALPPSGGTIASFERIDRTVGTGAEATPGAMVTVHYTGWLYDENAADKHGKKFDSSLDRAEPF
QFVLGGHQVIRGWDDGVAGMRVGGKRTLMIPPDYGYGDNGAGGVIPPGASLVFDVELLDVQPR
>Mature_143_residues
MRLLLTLCVALLLAGCAPALPPSGGTIASFERIDRTVGTGAEATPGAMVTVHYTGWLYDENAADKHGKKFDSSLDRAEPF
QFVLGGHQVIRGWDDGVAGMRVGGKRTLMIPPDYGYGDNGAGGVIPPGASLVFDVELLDVQPR

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=96, Percent_Identity=56.25, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI4503725, Length=96, Percent_Identity=56.25, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI4758380, Length=96, Percent_Identity=47.9166666666667, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI4503729, Length=111, Percent_Identity=45.045045045045, Blast_Score=95, Evalue=2e-20,
Organism=Homo sapiens, GI206725530, Length=102, Percent_Identity=49.0196078431373, Blast_Score=94, Evalue=3e-20,
Organism=Homo sapiens, GI17149844, Length=102, Percent_Identity=49.0196078431373, Blast_Score=94, Evalue=3e-20,
Organism=Homo sapiens, GI17149842, Length=102, Percent_Identity=49.0196078431373, Blast_Score=94, Evalue=3e-20,
Organism=Homo sapiens, GI224809329, Length=112, Percent_Identity=48.2142857142857, Blast_Score=92, Evalue=1e-19,
Organism=Homo sapiens, GI224809327, Length=112, Percent_Identity=48.2142857142857, Blast_Score=92, Evalue=1e-19,
Organism=Homo sapiens, GI4758384, Length=112, Percent_Identity=48.2142857142857, Blast_Score=92, Evalue=1e-19,
Organism=Homo sapiens, GI224809331, Length=112, Percent_Identity=48.2142857142857, Blast_Score=90, Evalue=6e-19,
Organism=Homo sapiens, GI192448443, Length=121, Percent_Identity=42.1487603305785, Blast_Score=79, Evalue=9e-16,
Organism=Homo sapiens, GI8923659, Length=148, Percent_Identity=34.4594594594595, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI33469985, Length=95, Percent_Identity=43.1578947368421, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI150010552, Length=109, Percent_Identity=37.6146788990826, Blast_Score=73, Evalue=7e-14,
Organism=Homo sapiens, GI206725547, Length=145, Percent_Identity=33.7931034482759, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI31317231, Length=146, Percent_Identity=34.2465753424658, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI4503727, Length=96, Percent_Identity=38.5416666666667, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87082390, Length=108, Percent_Identity=44.4444444444444, Blast_Score=80, Evalue=6e-17,
Organism=Escherichia coli, GI1789745, Length=105, Percent_Identity=46.6666666666667, Blast_Score=76, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17561782, Length=96, Percent_Identity=48.9583333333333, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71993519, Length=96, Percent_Identity=50, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17540882, Length=99, Percent_Identity=45.4545454545455, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506169, Length=88, Percent_Identity=40.9090909090909, Blast_Score=66, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17506167, Length=88, Percent_Identity=40.9090909090909, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17561778, Length=100, Percent_Identity=39, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320727, Length=100, Percent_Identity=55, Blast_Score=102, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324194, Length=112, Percent_Identity=50, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323566, Length=108, Percent_Identity=45.3703703703704, Blast_Score=85, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323482, Length=108, Percent_Identity=43.5185185185185, Blast_Score=81, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281363946, Length=99, Percent_Identity=57.5757575757576, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17352457, Length=99, Percent_Identity=57.5757575757576, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24655568, Length=96, Percent_Identity=55.2083333333333, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24647110, Length=108, Percent_Identity=50, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24583150, Length=103, Percent_Identity=47.5728155339806, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356629, Length=144, Percent_Identity=43.0555555555556, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15069; Mature: 15069

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLTLCVALLLAGCAPALPPSGGTIASFERIDRTVGTGAEATPGAMVTVHYTGWLYDE
CHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEC
NAADKHGKKFDSSLDRAEPFQFVLGGHQVIRGWDDGVAGMRVGGKRTLMIPPDYGYGDNG
CCCCCCCCHHHCCCCCCCCEEEEECCCEEEECCCCCCCCEEECCCEEEEECCCCCCCCCC
AGGVIPPGASLVFDVELLDVQPR
CCCCCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure
MRLLLTLCVALLLAGCAPALPPSGGTIASFERIDRTVGTGAEATPGAMVTVHYTGWLYDE
CHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEC
NAADKHGKKFDSSLDRAEPFQFVLGGHQVIRGWDDGVAGMRVGGKRTLMIPPDYGYGDNG
CCCCCCCCHHHCCCCCCCCEEEEECCCEEEECCCCCCCCEEECCCEEEEECCCCCCCCCC
AGGVIPPGASLVFDVELLDVQPR
CCCCCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]