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The map label for this gene is rnd [H]

Identifier: 84624243

GI number: 84624243

Start: 2884338

End: 2885429

Strand: Direct

Name: rnd [H]

Synonym: XOO_2586

Alternate gene names: 84624243

Gene position: 2884338-2885429 (Clockwise)

Preceding gene: 84624239

Following gene: 84624245

Centisome position: 58.38

GC content: 65.02

Gene sequence:

>1092_bases
GTGCCCCATTGGATTATCCACCCCTCCGAGCTGACCGACCGCCTGCAGGCAGCGCGCCCAGCGCGCATTGGCCTGGATAC
CGAATTCATTCGCGAACGCACCTATTGGCCGCAACTGGCGCTGGTGCAGATGGCCATCGGCGAGGAGATCCTGCTGATCG
ATCCGCTGATCCCCGGCATGAACGCGGCGCTCAAGGAGTGGTTGACCGCCACCGACATCGTCAAGGTGATGCATAGCGCC
AGCGAAGACTTGGTCACCTTCAAATGTGCGTGCGGGGTATTGCCGCGGCCGTTGTTCGACACCCAGATCGCCGCGGCGCT
GGCCGGTGTCGGCGGTGGCATGGGCTACCAGAAACTGGTGCAGGAAGTGACCGGCACCTTGCTCACCAAGGGCGAAACAC
GCTCGGACTGGATGCGTCGCCCGCTATCGCCGTCGCAGCTGGAGTACGCCGCCGACGACGTGCGGTACCTGTTTGCGATC
CACGACGAACTCACCCGTCGCCTCACCGAACAGAACCGCCTGGGCTGGCTGGCCGAAGATGCCGAGCGCCTGCTGGCCAC
GGTGGAGCACGACGATGGCGAACGCTGGCCGCATGTGAGCCTGCGCACCGCGCAATTCCTGGAACCAGCGGCGCAACGAC
GGTTGCTGCGCCTGCTGCGTTGGCGCGATCTGCAGGCGCGTCAAAGCGATCGCCCGCGCAGCTGGATTCTGGACAACGAG
CTGGCCAGCCAGCTGGCGCGGTTTCCACCCGCCGATCTGGACGCCTTGCTGCAGCAGTTCGATAAATTTCCCAAAGCGCC
GCGCAAGCTCGCCAATGCGGTGTGGGACGCGCTCAACACGCCATTGCCCGATGAAGAACATGCGCCATTGGCGCAAGCCG
CTACCGACGGCAACAAGGCCGTGCTCAAGCGCCTACAGGACACCGTGGCGCAGCGTAGCCGCGAACTTGGCTTGCCGGAT
GGTCTGCTGGCCTCGCGCCGGCACCTGGAAACCTTGATCGAACAGCGCAGCTGGCCCGCAGCGCTGGGCCAATGGCGGCG
CGCGCTACTGGAAGCGCAGGTGATGCCGCTGCTGGAAGCATCCGAAGTGTAA

Upstream 100 bases:

>100_bases
CACCACCTGCTCCTTCCAGTGCTCTGCCGCACGGCAGGCGATCGCGACGTTAGGCTATTCTGCGCGTTCTGCGCAAACCC
TTGCTGTCGACGGAAATCAC

Downstream 100 bases:

>100_bases
TTTTGCAAGCGGTTCGACACGTAAGCCGCAGCGATGCGGGCTTTTTCTTGGATTGCGTGGCAGCGGCATCGAGCCTCAGT
CCTCATCCTGCTCCGCTCAT

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MPHWIIHPSELTDRLQAARPARIGLDTEFIRERTYWPQLALVQMAIGEEILLIDPLIPGMNAALKEWLTATDIVKVMHSA
SEDLVTFKCACGVLPRPLFDTQIAAALAGVGGGMGYQKLVQEVTGTLLTKGETRSDWMRRPLSPSQLEYAADDVRYLFAI
HDELTRRLTEQNRLGWLAEDAERLLATVEHDDGERWPHVSLRTAQFLEPAAQRRLLRLLRWRDLQARQSDRPRSWILDNE
LASQLARFPPADLDALLQQFDKFPKAPRKLANAVWDALNTPLPDEEHAPLAQAATDGNKAVLKRLQDTVAQRSRELGLPD
GLLASRRHLETLIEQRSWPAALGQWRRALLEAQVMPLLEASEV

Sequences:

>Translated_363_residues
MPHWIIHPSELTDRLQAARPARIGLDTEFIRERTYWPQLALVQMAIGEEILLIDPLIPGMNAALKEWLTATDIVKVMHSA
SEDLVTFKCACGVLPRPLFDTQIAAALAGVGGGMGYQKLVQEVTGTLLTKGETRSDWMRRPLSPSQLEYAADDVRYLFAI
HDELTRRLTEQNRLGWLAEDAERLLATVEHDDGERWPHVSLRTAQFLEPAAQRRLLRLLRWRDLQARQSDRPRSWILDNE
LASQLARFPPADLDALLQQFDKFPKAPRKLANAVWDALNTPLPDEEHAPLAQAATDGNKAVLKRLQDTVAQRSRELGLPD
GLLASRRHLETLIEQRSWPAALGQWRRALLEAQVMPLLEASEV
>Mature_362_residues
PHWIIHPSELTDRLQAARPARIGLDTEFIRERTYWPQLALVQMAIGEEILLIDPLIPGMNAALKEWLTATDIVKVMHSAS
EDLVTFKCACGVLPRPLFDTQIAAALAGVGGGMGYQKLVQEVTGTLLTKGETRSDWMRRPLSPSQLEYAADDVRYLFAIH
DELTRRLTEQNRLGWLAEDAERLLATVEHDDGERWPHVSLRTAQFLEPAAQRRLLRLLRWRDLQARQSDRPRSWILDNEL
ASQLARFPPADLDALLQQFDKFPKAPRKLANAVWDALNTPLPDEEHAPLAQAATDGNKAVLKRLQDTVAQRSRELGLPDG
LLASRRHLETLIEQRSWPAALGQWRRALLEAQVMPLLEASEV

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=364, Percent_Identity=34.0659340659341, Blast_Score=144, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6324574, Length=328, Percent_Identity=27.4390243902439, Blast_Score=93, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 41071; Mature: 40939

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHWIIHPSELTDRLQAARPARIGLDTEFIRERTYWPQLALVQMAIGEEILLIDPLIPGM
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCH
NAALKEWLTATDIVKVMHSASEDLVTFKCACGVLPRPLFDTQIAAALAGVGGGMGYQKLV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
QEVTGTLLTKGETRSDWMRRPLSPSQLEYAADDVRYLFAIHDELTRRLTEQNRLGWLAED
HHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AERLLATVEHDDGERWPHVSLRTAQFLEPAAQRRLLRLLRWRDLQARQSDRPRSWILDNE
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHH
LASQLARFPPADLDALLQQFDKFPKAPRKLANAVWDALNTPLPDEEHAPLAQAATDGNKA
HHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHH
VLKRLQDTVAQRSRELGLPDGLLASRRHLETLIEQRSWPAALGQWRRALLEAQVMPLLEA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
SEV
CCC
>Mature Secondary Structure 
PHWIIHPSELTDRLQAARPARIGLDTEFIRERTYWPQLALVQMAIGEEILLIDPLIPGM
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCH
NAALKEWLTATDIVKVMHSASEDLVTFKCACGVLPRPLFDTQIAAALAGVGGGMGYQKLV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
QEVTGTLLTKGETRSDWMRRPLSPSQLEYAADDVRYLFAIHDELTRRLTEQNRLGWLAED
HHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AERLLATVEHDDGERWPHVSLRTAQFLEPAAQRRLLRLLRWRDLQARQSDRPRSWILDNE
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHH
LASQLARFPPADLDALLQQFDKFPKAPRKLANAVWDALNTPLPDEEHAPLAQAATDGNKA
HHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHH
VLKRLQDTVAQRSRELGLPDGLLASRRHLETLIEQRSWPAALGQWRRALLEAQVMPLLEA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
SEV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]