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The map label for this gene is xseA [H]

Identifier: 84624239

GI number: 84624239

Start: 2878055

End: 2879392

Strand: Direct

Name: xseA [H]

Synonym: XOO_2582

Alternate gene names: 84624239

Gene position: 2878055-2879392 (Clockwise)

Preceding gene: 84624238

Following gene: 84624243

Centisome position: 58.26

GC content: 67.49

Gene sequence:

>1338_bases
ATGGCCGAGCGCAACGAACAGATCCTTACTCCCAGCCAGCTCAATGCGCTAGCGCGCGACCTGCTGGAAGGCAGCTTCCC
GCTCGTATGGGTGGAAGCCGAACTGAGCAGCGTCACCCGGCCCTCGTCGGGGCATCTGTATTTCACGCTGAAGGATGCGC
GTGCGCAGATCCGTTGCGCGATGTTCAAGCCCAAAAGCACCTGGCTCAAATTCCAGCCGCGCGAAGGCTTGCGCGTGCTG
GCACGCGGGCGCCTGACCCTGTACGAAGCACGCGGCGACTACCAGCTGGTGCTCGACCATATGGAAGAAGCCGGCGAAGG
CGCGTTGCGTCGCGCCTTCGACGCACTGCGTGCACGCCTTGCTGCAGAAGGCCTGTTCGATGCCGAGCGCAAGCAGTCAC
TGCCGGCGCATGTTCAGCGGCTAGCGGTCATCACTTCGCCCAGCGGCGCGGCGGTGCGCGATGTGCTCAGCGTACTGGCG
CGGCGCTTTCCGCTACTCGAAGTGGATCTGCTGCCCTCGCTGGTACAAGGCGACAGCGCTGCCGCACAGATCACCTCGCT
GCTGCAACGCGCCGATGCGTCCGGGCGCTACGACGTCATCCTGATCACCCGCGGCGGCGGCTCGCTGGAAGATCTGTGGG
CCTTCAACGACGAACGCCTGGCGCGTGCGATTGCCGCTGCGCAGACGCCGGTGGTGTCTGCGGTCGGCCACGAGACCGAC
TTCAGCCTCAGCGATTTCGTGGCCGACGTGCGTGCGCCCACACCGTCGGTGGCGGCCGAATTGCTGGTGCCCGATCAACG
CGAGCTGGTCCCGCGCGTGCGACGCGCGCAGGCCCGCATGACCCAGCTGCAGCAACACGCCTTGGGCAATGCCATGCAAC
GCGCCGACCGGCTTGCGCTGCGCCTGCGTGCGCATAGCCCGCAGGCGCGCCTGCAACTGCTTCATCGCCGACAGGAAGAG
GCCGGTCGCCAGCTGGGTGCGCGCATGACGCAAGTGCTCGAGCGCTTGCAGGCGCGTGTGCAGCGTGGGCACGCGCAGGT
GCAATCACACAACCCGCAACGTCATCTGGCCGGCTTGCAGCAACGCCTGCGGGCATTGCATCCCCAGGCGGCGATGCAAC
GACGCTTGCAGCACGATCAACTGCAGCTGCGCAGCATTGCGCGCTCGCTGGAAGCGGTCAATCCGCTGGCCACGGTTGCG
CGTGGCTACGCCATCGTGACCCGCCCTGCCGATGGCAGCGTGGTGCGCAGCGCCGCCGAGGTGGCAGCAGGCGAGCGCCT
GCGCGCACAGCTGGCCGATGGCAGCATCGAGGTGCGCGTAGAGCCCGGCGAGCGCTGA

Upstream 100 bases:

>100_bases
GCCGCTACGTGTACGCGCTGGTCGTCGATGCGGCCTCCAATTGCATGGGCGTGTGTCAGCTAGTCACCCACGGTCTTCTT
CGCTACGGGATAATGCGGCG

Downstream 100 bases:

>100_bases
CGGCAAGCCATGCGCGACATTGTGGCTCCTGCAGCACTGCCGACGCTCAGCGCCGCCATGCACTCTTCGCAGGCGCCCAC
TCCATGGAGTGCCAGGAGGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MAERNEQILTPSQLNALARDLLEGSFPLVWVEAELSSVTRPSSGHLYFTLKDARAQIRCAMFKPKSTWLKFQPREGLRVL
ARGRLTLYEARGDYQLVLDHMEEAGEGALRRAFDALRARLAAEGLFDAERKQSLPAHVQRLAVITSPSGAAVRDVLSVLA
RRFPLLEVDLLPSLVQGDSAAAQITSLLQRADASGRYDVILITRGGGSLEDLWAFNDERLARAIAAAQTPVVSAVGHETD
FSLSDFVADVRAPTPSVAAELLVPDQRELVPRVRRAQARMTQLQQHALGNAMQRADRLALRLRAHSPQARLQLLHRRQEE
AGRQLGARMTQVLERLQARVQRGHAQVQSHNPQRHLAGLQQRLRALHPQAAMQRRLQHDQLQLRSIARSLEAVNPLATVA
RGYAIVTRPADGSVVRSAAEVAAGERLRAQLADGSIEVRVEPGER

Sequences:

>Translated_445_residues
MAERNEQILTPSQLNALARDLLEGSFPLVWVEAELSSVTRPSSGHLYFTLKDARAQIRCAMFKPKSTWLKFQPREGLRVL
ARGRLTLYEARGDYQLVLDHMEEAGEGALRRAFDALRARLAAEGLFDAERKQSLPAHVQRLAVITSPSGAAVRDVLSVLA
RRFPLLEVDLLPSLVQGDSAAAQITSLLQRADASGRYDVILITRGGGSLEDLWAFNDERLARAIAAAQTPVVSAVGHETD
FSLSDFVADVRAPTPSVAAELLVPDQRELVPRVRRAQARMTQLQQHALGNAMQRADRLALRLRAHSPQARLQLLHRRQEE
AGRQLGARMTQVLERLQARVQRGHAQVQSHNPQRHLAGLQQRLRALHPQAAMQRRLQHDQLQLRSIARSLEAVNPLATVA
RGYAIVTRPADGSVVRSAAEVAAGERLRAQLADGSIEVRVEPGER
>Mature_444_residues
AERNEQILTPSQLNALARDLLEGSFPLVWVEAELSSVTRPSSGHLYFTLKDARAQIRCAMFKPKSTWLKFQPREGLRVLA
RGRLTLYEARGDYQLVLDHMEEAGEGALRRAFDALRARLAAEGLFDAERKQSLPAHVQRLAVITSPSGAAVRDVLSVLAR
RFPLLEVDLLPSLVQGDSAAAQITSLLQRADASGRYDVILITRGGGSLEDLWAFNDERLARAIAAAQTPVVSAVGHETDF
SLSDFVADVRAPTPSVAAELLVPDQRELVPRVRRAQARMTQLQQHALGNAMQRADRLALRLRAHSPQARLQLLHRRQEEA
GRQLGARMTQVLERLQARVQRGHAQVQSHNPQRHLAGLQQRLRALHPQAAMQRRLQHDQLQLRSIARSLEAVNPLATVAR
GYAIVTRPADGSVVRSAAEVAAGERLRAQLADGSIEVRVEPGER

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=440, Percent_Identity=44.3181818181818, Blast_Score=347, Evalue=6e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49225; Mature: 49094

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERNEQILTPSQLNALARDLLEGSFPLVWVEAELSSVTRPSSGHLYFTLKDARAQIRCA
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEEEECCCCEEEEE
MFKPKSTWLKFQPREGLRVLARGRLTLYEARGDYQLVLDHMEEAGEGALRRAFDALRARL
EECCCCCCEEECCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAEGLFDAERKQSLPAHVQRLAVITSPSGAAVRDVLSVLARRFPLLEVDLLPSLVQGDSA
HHHHCCCCHHHHCCHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCEEHHHHHHHHCCCHH
AAQITSLLQRADASGRYDVILITRGGGSLEDLWAFNDERLARAIAAAQTPVVSAVGHETD
HHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCCC
FSLSDFVADVRAPTPSVAAELLVPDQRELVPRVRRAQARMTQLQQHALGNAMQRADRLAL
CCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRAHSPQARLQLLHRRQEEAGRQLGARMTQVLERLQARVQRGHAQVQSHNPQRHLAGLQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QRLRALHPQAAMQRRLQHDQLQLRSIARSLEAVNPLATVARGYAIVTRPADGSVVRSAAE
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
VAAGERLRAQLADGSIEVRVEPGER
HHHHHHHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure 
AERNEQILTPSQLNALARDLLEGSFPLVWVEAELSSVTRPSSGHLYFTLKDARAQIRCA
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEEEECCCCEEEEE
MFKPKSTWLKFQPREGLRVLARGRLTLYEARGDYQLVLDHMEEAGEGALRRAFDALRARL
EECCCCCCEEECCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAEGLFDAERKQSLPAHVQRLAVITSPSGAAVRDVLSVLARRFPLLEVDLLPSLVQGDSA
HHHHCCCCHHHHCCHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCEEHHHHHHHHCCCHH
AAQITSLLQRADASGRYDVILITRGGGSLEDLWAFNDERLARAIAAAQTPVVSAVGHETD
HHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCCC
FSLSDFVADVRAPTPSVAAELLVPDQRELVPRVRRAQARMTQLQQHALGNAMQRADRLAL
CCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRAHSPQARLQLLHRRQEEAGRQLGARMTQVLERLQARVQRGHAQVQSHNPQRHLAGLQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QRLRALHPQAAMQRRLQHDQLQLRSIARSLEAVNPLATVARGYAIVTRPADGSVVRSAAE
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
VAAGERLRAQLADGSIEVRVEPGER
HHHHHHHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]