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The map label for this gene is yciR [C]

Identifier: 84624079

GI number: 84624079

Start: 2694709

End: 2696430

Strand: Direct

Name: yciR [C]

Synonym: XOO_2422

Alternate gene names: 84624079

Gene position: 2694709-2696430 (Clockwise)

Preceding gene: 84624078

Following gene: 84624084

Centisome position: 54.55

GC content: 63.47

Gene sequence:

>1722_bases
ATGTGGAACCCTGTTAGTCCGCCCGGACTGGAGGTCGTCAAGCCCACACGGCTTGGCGCGGGCAACCCCGAATTGCTGCA
TTTAGTCGATGCGGCCGCGTCCGGCGGCCCGCCGCTGATGATTTTCCACGTCGACATCGATCACTTCGCCTCGATCAACG
AGAACATGAGTGGCGAGGTCGGCGACCAGGCGCTGACATTGGCCGCGCGTCGCCTTCAGGAATTTCTCGGAACCCGCGGC
AAACTGTGGCGTCATGGCAGCGATGAGATGATCGTGGTGGCAGTGCGCCGGGAAGACACGCCGCTGCCGGAAGACTTCGC
CGAAGAAATCCGCCAGCAACTGGAATTGCCGCTGTCGGTGTTGCCGTACACGTTGTTCATGACTGGCAAGGTCGGCATCA
GCCTGTGCCCGGAGCATTCCACCGCGGTGTCCACGCTCCTGGACTATGCCGAAGAAGCCAGCTACCAGGCGGCACGCGAA
GGCGGCAACACGGTGCGGCTGTACACCCACAACTCGGCCACCAACGCGCATAGCGAAAGCATCATTGCGCGGCAGATCGT
CGATGCGATTCCGCACGGCGAATTACGCCTGCGCTACCAACCGCTGGTGAGCGCGCGCGACGGCCGCATCGTTGGCATGG
AGGCGCTGCTGCGCTGGCAGTCGCCGACCCTGGGCATGCTGGTACCGGAGCGCTTCATGCGCACCGCCGAGCGCCTGGGC
GTGATCGTGCAGATCGGCGAATGGGTACTGCAGAACGCGGTGCGTCAGGCGCGTTTATGGCGCGACCAGGGCTTCGATGA
CTTCAGCATTGCGATAAACGTCTCCACGCTGCAGCTGCTGCGCCCGGGCTTCTTCAACGAAGTGATGGCGATGCTGCAGA
CCGCCGGTGTGCCGGCGCAGTTCGTCACGCTGGAGATCAACGAAAGCGCGTTGACCAACAACGTCAACTTCGTCCACGAG
ACGATGGCCAACCTGCGCAACGAAGGCATCAGCCTGAGCCTGGATAACTTCGGCACCGGCGATTCCAGTCTGAGCGCGCT
GGTGCGCTACCCGGTGGACCGGCTGAAGATCGACCGCAGTTTCATCAAAAGCGCACCTGCCGGCAGCCGCGAGGCGGCGA
TTGCGCGCGCCATCATCGCCATGGGTCACCAGCTCGGCATGACGGTCATTGCCAATGGGGTGGAATCGCAGGCGCAATTG
GGCTTCCTGCGTCGCAACGATTGCGACATCTTCCAGGGCTATCTGTTCGGTGAACCGATGTCGGCCGAGTCGGCCGGCAT
GGCACTGCGGCGCCGCTACCTGCGCCCGGAATCGTTCGCCGAAAGCCGCCCTGATCGCACCTTGCTGCTGCTGGACGACG
AAGAGAACGTGCTGCGCTCGCTGGTGCGCCTGTTCCGTCGCGATGGCTACCGGATTCTGGCCGCCGGCAACGTGCGCGAC
GCCTTCGACCTGCTCGCCACCAACGACGTGCAGGTGATCCTTTCCGATCAGCGCATGAGCGACATGAGCGGCACCGAGTT
CCTGGGCCGGGTCAAGATGCTCTACCCCGATACGGTGCGCCTGGTGCTCTCCGGCTACACGGACCTGGCCACGGTCACCG
AAGCCATCAACCGTGGCGCGATCTACCGCTTCCTGACCAAACCCTGGAACGACGACGAACTGCGCGAGCATATTCGTCAG
GCCTTCCGCACGCATGACGAGTTGCGGAACGTCCGGGAATAG

Upstream 100 bases:

>100_bases
CGCGATAGAATCGGCACCCGGAGCAGGCACGCGCGTGACGTTGCGCCTGCCCTATCACTCGGTCGGCGAGTCCGTCCACG
ACGATGGTGGACGTTGAGTC

Downstream 100 bases:

>100_bases
GGATTTGGGATTCGGGATTGGCTAAAGCGGGCTCCCGCGTCGTTGCGCCAGATGGCGCGGTGATCAATGAGCAACAGCGA
CGCCCGCTGCTGCCAATCCC

Product: c-di-GMP phosphodiesterase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MWNPVSPPGLEVVKPTRLGAGNPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEVGDQALTLAARRLQEFLGTRG
KLWRHGSDEMIVVAVRREDTPLPEDFAEEIRQQLELPLSVLPYTLFMTGKVGISLCPEHSTAVSTLLDYAEEASYQAARE
GGNTVRLYTHNSATNAHSESIIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAINVSTLQLLRPGFFNEVMAMLQTAGVPAQFVTLEINESALTNNVNFVHE
TMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRSFIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQL
GFLRRNDCDIFQGYLFGEPMSAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGAIYRFLTKPWNDDELREHIRQ
AFRTHDELRNVRE

Sequences:

>Translated_573_residues
MWNPVSPPGLEVVKPTRLGAGNPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEVGDQALTLAARRLQEFLGTRG
KLWRHGSDEMIVVAVRREDTPLPEDFAEEIRQQLELPLSVLPYTLFMTGKVGISLCPEHSTAVSTLLDYAEEASYQAARE
GGNTVRLYTHNSATNAHSESIIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAINVSTLQLLRPGFFNEVMAMLQTAGVPAQFVTLEINESALTNNVNFVHE
TMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRSFIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQL
GFLRRNDCDIFQGYLFGEPMSAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGAIYRFLTKPWNDDELREHIRQ
AFRTHDELRNVRE
>Mature_573_residues
MWNPVSPPGLEVVKPTRLGAGNPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEVGDQALTLAARRLQEFLGTRG
KLWRHGSDEMIVVAVRREDTPLPEDFAEEIRQQLELPLSVLPYTLFMTGKVGISLCPEHSTAVSTLLDYAEEASYQAARE
GGNTVRLYTHNSATNAHSESIIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAINVSTLQLLRPGFFNEVMAMLQTAGVPAQFVTLEINESALTNNVNFVHE
TMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRSFIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQL
GFLRRNDCDIFQGYLFGEPMSAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGAIYRFLTKPWNDDELREHIRQ
AFRTHDELRNVRE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=395, Percent_Identity=31.8987341772152, Blast_Score=208, Evalue=9e-55,
Organism=Escherichia coli, GI87081921, Length=396, Percent_Identity=30.8080808080808, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI226510982, Length=281, Percent_Identity=29.1814946619217, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI87081980, Length=238, Percent_Identity=32.7731092436975, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081845, Length=261, Percent_Identity=31.0344827586207, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787055, Length=257, Percent_Identity=32.295719844358, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786507, Length=256, Percent_Identity=28.515625, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=29.957805907173, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1788502, Length=252, Percent_Identity=28.1746031746032, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081743, Length=236, Percent_Identity=28.8135593220339, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788849, Length=232, Percent_Identity=28.448275862069, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI87082096, Length=243, Percent_Identity=25.5144032921811, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787410, Length=133, Percent_Identity=32.3308270676692, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=30.4, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 64016; Mature: 64016

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50042 CNMP_BINDING_3 ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWNPVSPPGLEVVKPTRLGAGNPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEV
CCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECHHHHHHCCCCCCCCC
GDQALTLAARRLQEFLGTRGKLWRHGSDEMIVVAVRREDTPLPEDFAEEIRQQLELPLSV
CHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHH
LPYTLFMTGKVGISLCPEHSTAVSTLLDYAEEASYQAAREGGNTVRLYTHNSATNAHSES
HCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHH
IIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHCC
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAINVSTLQLLRPGFFNEVMAMLQTAGVPAQ
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHCCCHHHHHHHHHHHCCCCEE
FVTLEINESALTNNVNFVHETMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRS
EEEEEECCHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHH
FIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQLGFLRRNDCDIFQGYLFGEPM
HHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCCCCC
SAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
CCHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHH
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGA
HHHHHCCCCEEEEEECCHHCCCCCHHHHHHHHEECCHHHHHHHHCCHHHHHHHHHHCCCC
IYRFLTKPWNDDELREHIRQAFRTHDELRNVRE
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWNPVSPPGLEVVKPTRLGAGNPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEV
CCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECHHHHHHCCCCCCCCC
GDQALTLAARRLQEFLGTRGKLWRHGSDEMIVVAVRREDTPLPEDFAEEIRQQLELPLSV
CHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHH
LPYTLFMTGKVGISLCPEHSTAVSTLLDYAEEASYQAAREGGNTVRLYTHNSATNAHSES
HCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHH
IIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHCC
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAINVSTLQLLRPGFFNEVMAMLQTAGVPAQ
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHCCCHHHHHHHHHHHCCCCEE
FVTLEINESALTNNVNFVHETMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRS
EEEEEECCHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHH
FIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQLGFLRRNDCDIFQGYLFGEPM
HHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCCCCC
SAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
CCHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHH
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGA
HHHHHCCCCEEEEEECCHHCCCCCHHHHHHHHEECCHHHHHHHHCCHHHHHHHHHHCCCC
IYRFLTKPWNDDELREHIRQAFRTHDELRNVRE
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]