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The map label for this gene is fadN [H]

Identifier: 84624052

GI number: 84624052

Start: 2658526

End: 2660898

Strand: Direct

Name: fadN [H]

Synonym: XOO_2395

Alternate gene names: 84624052

Gene position: 2658526-2660898 (Clockwise)

Preceding gene: 84624051

Following gene: 84624053

Centisome position: 53.81

GC content: 64.77

Gene sequence:

>2373_bases
ATGTCCAATCCGTTGCTAGTTCGTCGCGCCGCCGTGCTCGGTGCCGGCGTCATGGGCGCGCAGATCGCCGCCCACCTCAC
CAATGCCGGTGTCGACACCGTGCTGTTCGACCTGCCCGCCAAGGAAGGCCCGGCCGACGGCATCGTGCTCAAGGCGATTG
CCAATCTCGGCAAGCTGAGCCCTGCACCGCTCGCCAGCAAGGCGCTGGCCGAGGCGATCACGCCGGCCAACTACGAGAGC
GGCCTGGAACAACTGCGCCATTGCGATCTGATCATCGAAGCGATCGCCGAGCGCATGGATTGGAAGCAGGACCTGTACAA
GAAGATCGCCCCGTTCGTCTCCGCGCATGCCGTGCTGGCGTCCAATACCTCGGGCCTGGGCATCAACAAGCTCGCCGACG
TGCTGCCGGAGCAGCTGCGCCATCGCTTCTGCGGCGTGCATTTCTTCAATCCGCCGCGCTACATGCACCTGGCCGAGTTG
ATCCCGGCCAAGGGCACCGACAAAGCCGTGCTCGAAGGCCTGGAAGCGTTCCTGGTCACCACGCTCGGCAAGGGTGTTGT
GTATGCCAAGGACACGCCGAATTTCATCGGCAACCGCATCGGCGTGTTCTCGATCCTGTCCACCATCCACCACACGCAGC
AATTCGGCCTGGGCTTCGATGAGGTCGATGCGCTGACCGGCCCGCTGGTCGGTCGCCCGAAGTCGGCAACCTACCGCACC
TCGGACGTGGTCGGCCTGGACACCATGGCGCACGTGATCAAGACCATGGGCGACACCCTGCCGGACGACCCGTGGCACCA
GTATTTCACCTCGCCCAAGTGGCTGGATGCGCTGATCGCCAAAGGTGCGCTGGGCCAGAAGGTCGGCGCCGGCATCTTCC
GCAAGGTCGGCAAGGATATCGTGGTGGTCGATCTGGAGAAGCAGGACTACCGCCCGGCAGATCGCGTCGCTGCGCCGGAA
GTGGTGGATATCCTCAAGATCAAGAACCCGGCCGAAAAGTTCGCCACGCTGCGCGAGAGCGAGCACCCGCAGGCGCAGTT
CCTGTGGGCCACGTTCCGCGACCTGTTCCACTACAGCGCCGTCCATCTGGCCGATATCGCCGAAACCGCGCGCGATGTGG
ATCTGGCGACCCGCTGGGGCTACGGCTGGTCGCTGGGCCCGTTCGAAACCTGGCAGGCCGCCGGCTGGAAGCAGGTGGCG
CAGTGGATTGCCGAAGACATTTCCAATGGCAAGAGCATGAGCAGCGCGCCGCTGCCGAACTGGGTGTTCGATGGTCGCGA
CGGCGTGCATGGCGCCGAAGGCTCGTACAGCCCGGCGCGCGATGCCAAGCTGCCGCGTTCGGCATTGCCGGTGTACACGC
GTCAGCGCTTCCCCGATCCGTTGCTGGGCGAGCAGTTCTCGCCCGGCGAAACCGTGTTCGAAAACGACGGCGTGCGCATG
TGGCATGACGGCGACGACATCGCGGTGGTCAGCTTCAAGACCAAGATGAACACCGTCTCCGACCACGTGCTCAACGGCTT
GCAGGACGTCGTTGGTCGCGCCGAGAAGGACTTCGCTGGTCTGGTGATCTGGCAGCAGAAAGAGCCCTTCTCCGCCGGTG
CCGATCTGACCGGCGCGCTTGGCCTGCTGCAGGCCGGCAAGGTCGATGCGTTCGAAGCGCTGGTCGCCAACTTCCAGGCC
ACCAGCCAGCGCATCAAGTACGCACAGGTGCCGGTGATTTCGGCCGTGCGCGGTCTGGCACTGGGCGGCGGTTGCGAATT
CCAGATGCACAGCGCCAAGACCGTCGCCTCGCTGGAAAGCTACATCGGCCTGGTCGAAGCCGGCGTCGGCTTGCTGCCGG
CTGGCGGCGGCTTGAAGGAGATCGCGGTGCGTGCGTCGATTGCCGCAGGTCCGGGCGGCGATGTGTTCGCCGAGTTGAAG
AAGACCTTCGAAACCGTGGCAATGGCCAAGGTCTCCAACTCGGCGGTCAACGCCCAGGAACTTGGCCTGCTGCGTGCCAC
CGACAAGGTCGTGTTCAACAGCTTTGAGGCGCTGCACATCGCCAAGGCCGAGGCACGCGCATTGGCCGAGGGCGGCTACC
GCGCCCCGCTGCCGGCACGCCGCATCCAGGTCGCCGGCGACGTCGGCATCGCCACCTTCAAGATGCTGCTGGTCAACATG
CTGGAAGGCCGCTTCATCAGCGAATACGACTACGAGATCGCCACCCGCATCGCCACGGTGGTCTGCGGCGGCGAAGTGGA
TCGCGGCGCGCTGGTGGACGAAGAATGGCTGCTCAAGCTGGAGCGCAAGCACTTTGTCGAACTGGCCCAGCAGGAAAAAA
CCCAGGCGCGGATTGGGCACATGCTCAAGACGGGGAAGCCGTTGAGGAACTGA

Upstream 100 bases:

>100_bases
CGATCACCGCGCGCGTGCCGCGCGCGAACTCATTCGTTTCGCGGAACCCGGTTTCCGTGCTCACTCCACACCGTAAACGT
TCCTCAAGAGGCTTATCGCT

Downstream 100 bases:

>100_bases
GATGCGGGATTGGGGATTCGCAACGGCGATTCCCCAGCCCTGCACGAGCTTCGCTTCCACCAAATTTATCCGCCGGGTTG
GACCATTCGGACATCGGGAT

Product: 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MSNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAIANLGKLSPAPLASKALAEAITPANYES
GLEQLRHCDLIIEAIAERMDWKQDLYKKIAPFVSAHAVLASNTSGLGINKLADVLPEQLRHRFCGVHFFNPPRYMHLAEL
IPAKGTDKAVLEGLEAFLVTTLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQQFGLGFDEVDALTGPLVGRPKSATYRT
SDVVGLDTMAHVIKTMGDTLPDDPWHQYFTSPKWLDALIAKGALGQKVGAGIFRKVGKDIVVVDLEKQDYRPADRVAAPE
VVDILKIKNPAEKFATLRESEHPQAQFLWATFRDLFHYSAVHLADIAETARDVDLATRWGYGWSLGPFETWQAAGWKQVA
QWIAEDISNGKSMSSAPLPNWVFDGRDGVHGAEGSYSPARDAKLPRSALPVYTRQRFPDPLLGEQFSPGETVFENDGVRM
WHDGDDIAVVSFKTKMNTVSDHVLNGLQDVVGRAEKDFAGLVIWQQKEPFSAGADLTGALGLLQAGKVDAFEALVANFQA
TSQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLESYIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELK
KTFETVAMAKVSNSAVNAQELGLLRATDKVVFNSFEALHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNM
LEGRFISEYDYEIATRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGHMLKTGKPLRN

Sequences:

>Translated_790_residues
MSNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAIANLGKLSPAPLASKALAEAITPANYES
GLEQLRHCDLIIEAIAERMDWKQDLYKKIAPFVSAHAVLASNTSGLGINKLADVLPEQLRHRFCGVHFFNPPRYMHLAEL
IPAKGTDKAVLEGLEAFLVTTLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQQFGLGFDEVDALTGPLVGRPKSATYRT
SDVVGLDTMAHVIKTMGDTLPDDPWHQYFTSPKWLDALIAKGALGQKVGAGIFRKVGKDIVVVDLEKQDYRPADRVAAPE
VVDILKIKNPAEKFATLRESEHPQAQFLWATFRDLFHYSAVHLADIAETARDVDLATRWGYGWSLGPFETWQAAGWKQVA
QWIAEDISNGKSMSSAPLPNWVFDGRDGVHGAEGSYSPARDAKLPRSALPVYTRQRFPDPLLGEQFSPGETVFENDGVRM
WHDGDDIAVVSFKTKMNTVSDHVLNGLQDVVGRAEKDFAGLVIWQQKEPFSAGADLTGALGLLQAGKVDAFEALVANFQA
TSQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLESYIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELK
KTFETVAMAKVSNSAVNAQELGLLRATDKVVFNSFEALHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNM
LEGRFISEYDYEIATRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGHMLKTGKPLRN
>Mature_789_residues
SNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAIANLGKLSPAPLASKALAEAITPANYESG
LEQLRHCDLIIEAIAERMDWKQDLYKKIAPFVSAHAVLASNTSGLGINKLADVLPEQLRHRFCGVHFFNPPRYMHLAELI
PAKGTDKAVLEGLEAFLVTTLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQQFGLGFDEVDALTGPLVGRPKSATYRTS
DVVGLDTMAHVIKTMGDTLPDDPWHQYFTSPKWLDALIAKGALGQKVGAGIFRKVGKDIVVVDLEKQDYRPADRVAAPEV
VDILKIKNPAEKFATLRESEHPQAQFLWATFRDLFHYSAVHLADIAETARDVDLATRWGYGWSLGPFETWQAAGWKQVAQ
WIAEDISNGKSMSSAPLPNWVFDGRDGVHGAEGSYSPARDAKLPRSALPVYTRQRFPDPLLGEQFSPGETVFENDGVRMW
HDGDDIAVVSFKTKMNTVSDHVLNGLQDVVGRAEKDFAGLVIWQQKEPFSAGADLTGALGLLQAGKVDAFEALVANFQAT
SQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLESYIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELKK
TFETVAMAKVSNSAVNAQELGLLRATDKVVFNSFEALHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNML
EGRFISEYDYEIATRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGHMLKTGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=296, Percent_Identity=31.7567567567568, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI296179427, Length=313, Percent_Identity=31.629392971246, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI20127408, Length=303, Percent_Identity=28.7128712871287, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI261878539, Length=318, Percent_Identity=25.4716981132075, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI68989263, Length=318, Percent_Identity=25.4716981132075, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1790281, Length=316, Percent_Identity=26.5822784810127, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1787661, Length=307, Percent_Identity=28.6644951140065, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788682, Length=334, Percent_Identity=26.0479041916168, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17549919, Length=300, Percent_Identity=29, Blast_Score=107, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17553560, Length=298, Percent_Identity=28.1879194630872, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17563036, Length=298, Percent_Identity=28.8590604026846, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17558304, Length=328, Percent_Identity=29.8780487804878, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=328, Percent_Identity=30.7926829268293, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508951, Length=328, Percent_Identity=30.7926829268293, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144276, Length=292, Percent_Identity=31.8493150684932, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71985923, Length=268, Percent_Identity=26.1194029850746, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71985930, Length=257, Percent_Identity=25.2918287937743, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583077, Length=399, Percent_Identity=27.3182957393484, Blast_Score=87, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24583079, Length=399, Percent_Identity=27.3182957393484, Blast_Score=87, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19921000, Length=399, Percent_Identity=27.3182957393484, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 85433; Mature: 85302

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAIANLGKLS
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCHHHHHHHHHHCCCC
PAPLASKALAEAITPANYESGLEQLRHCDLIIEAIAERMDWKQDLYKKIAPFVSAHAVLA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHC
SNTSGLGINKLADVLPEQLRHRFCGVHFFNPPRYMHLAELIPAKGTDKAVLEGLEAFLVT
CCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQQFGLGFDEVDALTGPLVGRPKSATYRT
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
SDVVGLDTMAHVIKTMGDTLPDDPWHQYFTSPKWLDALIAKGALGQKVGAGIFRKVGKDI
CCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
VVVDLEKQDYRPADRVAAPEVVDILKIKNPAEKFATLRESEHPQAQFLWATFRDLFHYSA
EEEECCCCCCCCHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VHLADIAETARDVDLATRWGYGWSLGPFETWQAAGWKQVAQWIAEDISNGKSMSSAPLPN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
WVFDGRDGVHGAEGSYSPARDAKLPRSALPVYTRQRFPDPLLGEQFSPGETVFENDGVRM
CEECCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCCEECCCCEEE
WHDGDDIAVVSFKTKMNTVSDHVLNGLQDVVGRAEKDFAGLVIWQQKEPFSAGADLTGAL
EECCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHH
GLLQAGKVDAFEALVANFQATSQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLES
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCHHHHHHHHH
YIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELKKTFETVAMAKVSNSAVNAQE
HHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LGLLRATDKVVFNSFEALHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNM
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHHHHHHHHHH
LEGRFISEYDYEIATRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGH
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLKTGKPLRN
HHHCCCCCCC
>Mature Secondary Structure 
SNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAIANLGKLS
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCHHHHHHHHHHCCCC
PAPLASKALAEAITPANYESGLEQLRHCDLIIEAIAERMDWKQDLYKKIAPFVSAHAVLA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHC
SNTSGLGINKLADVLPEQLRHRFCGVHFFNPPRYMHLAELIPAKGTDKAVLEGLEAFLVT
CCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQQFGLGFDEVDALTGPLVGRPKSATYRT
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
SDVVGLDTMAHVIKTMGDTLPDDPWHQYFTSPKWLDALIAKGALGQKVGAGIFRKVGKDI
CCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
VVVDLEKQDYRPADRVAAPEVVDILKIKNPAEKFATLRESEHPQAQFLWATFRDLFHYSA
EEEECCCCCCCCHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VHLADIAETARDVDLATRWGYGWSLGPFETWQAAGWKQVAQWIAEDISNGKSMSSAPLPN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
WVFDGRDGVHGAEGSYSPARDAKLPRSALPVYTRQRFPDPLLGEQFSPGETVFENDGVRM
CEECCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCCEECCCCEEE
WHDGDDIAVVSFKTKMNTVSDHVLNGLQDVVGRAEKDFAGLVIWQQKEPFSAGADLTGAL
EECCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHH
GLLQAGKVDAFEALVANFQATSQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLES
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCHHHHHHHHH
YIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELKKTFETVAMAKVSNSAVNAQE
HHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LGLLRATDKVVFNSFEALHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNM
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHHHHHHHHHH
LEGRFISEYDYEIATRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGH
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLKTGKPLRN
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]