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The map label for this gene is asnC [H]

Identifier: 84623953

GI number: 84623953

Start: 2558827

End: 2560221

Strand: Direct

Name: asnC [H]

Synonym: XOO_2296

Alternate gene names: 84623953

Gene position: 2558827-2560221 (Clockwise)

Preceding gene: 84623939

Following gene: 84623954

Centisome position: 51.8

GC content: 63.15

Gene sequence:

>1395_bases
ATGACGGTGGTCAGCGTTGAACATGCGCTTGCGGGGAAGCTCCCCGAAGGCGGCGAAGTCACGGTACGGGGGTGGGTACG
CACCTTGCGCGGATCTGCCGGACTGGCCTTCATCAACGTGACCGACGGCTCGTGCTTCGCTCCGATCCAGGTGGTAGCCA
ACGACACGCTGCCCAATTTCGACGAGATCAAGCGCCTGACCAGTGGCTGCTCACTGATCGCCAAGGGCGTGCTGGTGAAG
TCGCAGGGCAAGGGCCAGTCGTTCGAGATCCAGGCCAGCGGCGTGGAGATCGTCGGCTGGGTCGAAGACCCGCTGACCTA
TCCGATCCAGCCCAAGCCGATGACGCCGGAGTTCCTGCGCGAAGTGGCGCACTTGCGCCCGCGCACCAATCTGTTCGGCG
CGGTCACACGTATCCGCAACTGTCTGGCGCAGGCGGTGCACCGCTTCTTCCACCAGAACGGCTTCAACTGGATCAGCACA
CCCATCATCACCACCTCCGACGCCGAAGGCGCCGGGCAGATGTTCCGCGTCTCCACGCTGGACATGGTCAACCTGCCACG
CGATGCCACTGGCAATGTGGATTTCAGCCGCGACTTCTTCGGCAAGGAAACCTTCCTCACCGTGTCCGGCCAGCTCAACG
TGGAGGCCTACTGTCTGGCGCTGAGCAAGGTCTACACCTTCGGGCCAACCTTCCGCGCCGAGAACAGCCATACCACGCGC
CACCTGGCCGAGTTCTGGATGATCGAGCCGGAGATCGCCTTTGCCGATCTGGCCGAAGACGCGCGCCTGGCCGAGCAGTT
CCTCAAGTATGTGTTCCGCGCGGTGCTGGACGAACGTGGCGACGATCTGGCGTTCCTCGCCGAGCGCGTGGACAAGAAGG
CGATCAGCAAGCTGGAAGCCTTCATCAATGCGCCGTTCGAGCAGATCGACTACACCGATGCGGTCAAGCTGCTGCAACAC
GCTGGCAAGACCTTCGATTTCCCAGTGGAATGGGGCCTGGACCTGCAGACCGAGCACGAACGCTGGCTGACCGAAGAACA
TATTGGCCGCCCGGTGGTGGTCACCAATTATCCCGAGCACATCAAGGCGTTCTACATGCGCTTGAACGACGACGGCAAGA
CCGTCGCCGCGATGGACGTGCTGGCACCGGGTATCGGCGAGATCATCGGCGGCAGCCAGCGCGAAGAGCGCCTGGATGTG
CTCGACGCACGCATGGCGCAGTTCGGCCTGGATAAGGAGCACTACAGCTGGTACCGCGATTTCCGTCGCTACGGCTCGGT
GCCGCATGCCGGCTTCGGTTTGGGCTTCGAGCGTCTGGTGGTCTATGTCTGCGGGCTAAGCAACATCCGCGACGCGATCC
CCTACCCGCGCGCGCCGGGCAGCGCGGAATTCTGA

Upstream 100 bases:

>100_bases
AAGCGTAGCCGTCGGCAACCTGTTCACAGATGCTCGCGCCGGCGCGGCCGCAGCCAGTAAACTCGCAGGCCATTCAAGGT
CGCTACGGCGAGGAACAGTC

Downstream 100 bases:

>100_bases
GGTGAGCTTGCCGGCCGCCATCCCCATATTTCAATCGCTGGCCTTCGGGCTGGCGGGGATCACGGGGGGGCTGACAGCGA
TCCGTAGCGTGCTGCTGGCG

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNFDEIKRLTSGCSLIAKGVLVK
SQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLREVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWIST
PIITTSDAEGAGQMFRVSTLDMVNLPRDATGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTR
HLAEFWMIEPEIAFADLAEDARLAEQFLKYVFRAVLDERGDDLAFLAERVDKKAISKLEAFINAPFEQIDYTDAVKLLQH
AGKTFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDV
LDARMAQFGLDKEHYSWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF

Sequences:

>Translated_464_residues
MTVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNFDEIKRLTSGCSLIAKGVLVK
SQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLREVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWIST
PIITTSDAEGAGQMFRVSTLDMVNLPRDATGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTR
HLAEFWMIEPEIAFADLAEDARLAEQFLKYVFRAVLDERGDDLAFLAERVDKKAISKLEAFINAPFEQIDYTDAVKLLQH
AGKTFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDV
LDARMAQFGLDKEHYSWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
>Mature_463_residues
TVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNFDEIKRLTSGCSLIAKGVLVKS
QGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLREVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWISTP
IITTSDAEGAGQMFRVSTLDMVNLPRDATGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTRH
LAEFWMIEPEIAFADLAEDARLAEQFLKYVFRAVLDERGDDLAFLAERVDKKAISKLEAFINAPFEQIDYTDAVKLLQHA
GKTFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVL
DARMAQFGLDKEHYSWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=463, Percent_Identity=42.3326133909287, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI4758762, Length=455, Percent_Identity=27.9120879120879, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI45439306, Length=350, Percent_Identity=28.8571428571429, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=67.5965665236051, Blast_Score=667, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17556372, Length=425, Percent_Identity=32.4705882352941, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI71984122, Length=456, Percent_Identity=30.4824561403509, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=341, Percent_Identity=29.0322580645161, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=473, Percent_Identity=35.9408033826639, Blast_Score=290, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6321807, Length=460, Percent_Identity=31.304347826087, Blast_Score=209, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6323011, Length=348, Percent_Identity=28.448275862069, Blast_Score=109, Evalue=9e-25,
Organism=Drosophila melanogaster, GI19922416, Length=452, Percent_Identity=35.6194690265487, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI19921528, Length=452, Percent_Identity=29.8672566371681, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI17136276, Length=487, Percent_Identity=27.3100616016427, Blast_Score=116, Evalue=4e-26,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 51893; Mature: 51761

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNF
CEEEEECHHHHCCCCCCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCH
DEIKRLTSGCSLIAKGVLVKSQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLR
HHHHHHHHHHHHHHHCCEEECCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCHHHHH
EVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWISTPIITTSDAEGAGQMFRVSTL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEECCCCCCCCEEEEEEE
DMVNLPRDATGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTR
HHHCCCCCCCCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEECCCCCHHH
HLAEFWMIEPEIAFADLAEDARLAEQFLKYVFRAVLDERGDDLAFLAERVDKKAISKLEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FINAPFEQIDYTDAVKLLQHAGKTFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEH
HHCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCHHH
IKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAQFGLDKEHYSWYRD
HHHHHHEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
FRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
HHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNF
EEEEECHHHHCCCCCCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCH
DEIKRLTSGCSLIAKGVLVKSQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLR
HHHHHHHHHHHHHHHCCEEECCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCHHHHH
EVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWISTPIITTSDAEGAGQMFRVSTL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEECCCCCCCCEEEEEEE
DMVNLPRDATGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTR
HHHCCCCCCCCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEECCCCCHHH
HLAEFWMIEPEIAFADLAEDARLAEQFLKYVFRAVLDERGDDLAFLAERVDKKAISKLEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FINAPFEQIDYTDAVKLLQHAGKTFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEH
HHCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCHHH
IKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAQFGLDKEHYSWYRD
HHHHHHEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
FRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
HHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]