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The map label for this gene is glk [H]

Identifier: 84623849

GI number: 84623849

Start: 2431128

End: 2432135

Strand: Direct

Name: glk [H]

Synonym: XOO_2192

Alternate gene names: 84623849

Gene position: 2431128-2432135 (Clockwise)

Preceding gene: 84623848

Following gene: 84623850

Centisome position: 49.21

GC content: 66.87

Gene sequence:

>1008_bases
ATGACCGCTCCTTCCAAGCCGGTGCTGGTTGCCGATATCGGCGGAACCAATGCGCGTTTCGCGCTGGCCGATGTCGACGC
CTCGGTGCCGTTACTGGATGACACCTCGCGCGAATTTGCCGTGGTGGACTTCACCTCGCTCGGCGAAGCCGCGCGCTATT
ATCTCGACCAGATCGGCGTGCAGGCCACCCAGGGCGTGTTCGCGGTGGCCGGCCGCGTGGATGGCGACGAAGCACGTATC
ACCAATCACCCGTGGGTGATCTCGCGTTCGCGCACTGCCAGCATGCTGGGTTTCAGTACCTTGCACCTGATCAACGACTT
CGCCGCGCAGGCGATGGCGATCAGCCTGCTGCGTCCGCAGGACGTGGTGCAGGTGGGCGGCGCCAGTTGGCGCCCGGCGC
CGATCGATCAGCCGCGCAACTACGGCGTGATCGGCCCCGGCACCGGCCTGGGCGTGGGTGGCCTGATCATCCGCCACGGG
CGCTGCTTTCCGCTGGAAACCGAAGGCGGCCATGTCAGCTTCCCGCCCGGCACGCCGGAAGAAATCCGCATCCTGGAAAT
CCTCTCCGAGCAGTTCGGCCGGGTTTCCAACGAGCGCCTGATCTGCGGCCCGGGCCTGGTCAACATCCACCGCGCGCTGA
GTGAGATTGCCGGAGTCGATCCGGGCCCGCTGCAACCCAAGGACATCACCGCACGCGCCGCGGCGGGCGACCCGCGTTCG
TCGCGCACGATCGATTTGTTCTGCGCCATCTTCGGAGCGATCGCTGGCGACATGGTGCTCATGCAGGGTGCCTGGGACGG
CGTGTTCCTTACCGGCGGGCTGGTGCCCAAGGTGCTGGATTCGCTGCAGCATTCCGGCTTTCGCCAGCGCTTCGAACACA
AGGGCCGTTTCTCCGCGATCATGTCGCGGGTGCCGTCGCTGGCGGTCATGCACCCGCATGCCGGCCTGCTCGGCGCCGCC
GCGTATGCGGTGGATGCACAACGTCAGCCCCCCGGGGAACAGCGATGA

Upstream 100 bases:

>100_bases
ACGCCGCACTGCCGCTGCAGCCCTACCCGGCCGGCAGCTGGGGTCCCGAATCGGCCACCCACTTCCTGCCCCCAGCCACC
GACGCACAGGCAAACAACGC

Downstream 100 bases:

>100_bases
ATCTGCAGGACAACCCGCGCATCACCCTGGTGCGCTACGACGACCCGGCCGAATGGAACGAAGCGGTGGCCAGCGAAATG
GTGGATCTGCTGGAACAGGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFTSLGEAARYYLDQIGVQATQGVFAVAGRVDGDEARI
TNHPWVISRSRTASMLGFSTLHLINDFAAQAMAISLLRPQDVVQVGGASWRPAPIDQPRNYGVIGPGTGLGVGGLIIRHG
RCFPLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRS
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAIMSRVPSLAVMHPHAGLLGAA
AYAVDAQRQPPGEQR

Sequences:

>Translated_335_residues
MTAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFTSLGEAARYYLDQIGVQATQGVFAVAGRVDGDEARI
TNHPWVISRSRTASMLGFSTLHLINDFAAQAMAISLLRPQDVVQVGGASWRPAPIDQPRNYGVIGPGTGLGVGGLIIRHG
RCFPLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRS
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAIMSRVPSLAVMHPHAGLLGAA
AYAVDAQRQPPGEQR
>Mature_334_residues
TAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFTSLGEAARYYLDQIGVQATQGVFAVAGRVDGDEARIT
NHPWVISRSRTASMLGFSTLHLINDFAAQAMAISLLRPQDVVQVGGASWRPAPIDQPRNYGVIGPGTGLGVGGLIIRHGR
CFPLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRSS
RTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAIMSRVPSLAVMHPHAGLLGAAA
YAVDAQRQPPGEQR

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=319, Percent_Identity=41.692789968652, Blast_Score=234, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 35585; Mature: 35454

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFTSLGEAARYYLDQIGV
CCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCC
QATQGVFAVAGRVDGDEARITNHPWVISRSRTASMLGFSTLHLINDFAAQAMAISLLRPQ
HHHCCEEEEEECCCCCCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DVVQVGGASWRPAPIDQPRNYGVIGPGTGLGVGGLIIRHGRCFPLETEGGHVSFPPGTPE
HHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEEECCCEEEECCCCCEEECCCCCHH
EIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRS
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCC
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAI
CCHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHH
MSRVPSLAVMHPHAGLLGAAAYAVDAQRQPPGEQR
HHHCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFTSLGEAARYYLDQIGV
CCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCC
QATQGVFAVAGRVDGDEARITNHPWVISRSRTASMLGFSTLHLINDFAAQAMAISLLRPQ
HHHCCEEEEEECCCCCCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DVVQVGGASWRPAPIDQPRNYGVIGPGTGLGVGGLIIRHGRCFPLETEGGHVSFPPGTPE
HHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEEECCCEEEECCCCCEEECCCCCHH
EIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRS
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCC
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAI
CCHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHH
MSRVPSLAVMHPHAGLLGAAAYAVDAQRQPPGEQR
HHHCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]