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The map label for this gene is cmk [H]

Identifier: 84623706

GI number: 84623706

Start: 2267583

End: 2268266

Strand: Direct

Name: cmk [H]

Synonym: XOO_2049

Alternate gene names: 84623706

Gene position: 2267583-2268266 (Clockwise)

Preceding gene: 84623699

Following gene: 84623707

Centisome position: 45.9

GC content: 65.5

Gene sequence:

>684_bases
ATGACCGACCTGTCGCCCGTCCTCACCATCGATGGCCCCTCCGGTGCCGGCAAGGGCACCGTGAGCCGGATCGTGGCCGC
CCGGCTTGGCTGGCACTACCTCGATTCGGGCGCACTGTATCGCGCTGTCGGTGTTGCGGCGAGCTGGGCCGACCTGGATG
TCTCCGACCCGGCAGCACTGGTGCGCTGCACCTTCGACACCAAGGTGGAATTCGACGATGCGGGGGAGGCAGGGCTGCGA
GTGCTGGTCAATGGCGCAGATGTGACCAGTGAGCTGCGCTTGGAAACTACCGGCGCGCTGGCCTCAGCGATTGCCGCCAT
TCCCGAGGTGCGCAGCGCCCTGAAAGAGCGCCAACGCGCATTCAGGCGGGCGCCCGGGCTGGTTGCCGACGGGCGCGACA
TGGGGACGGTGATCTTCCCGGATGCCGCCTTCAAGGTCTTTCTGACCGCCAGTGCCGAAGAACGTGCGGGCCGTCGCCAT
AAACAGTTGATGGAAAAGGGTGTTTCGGTTACCTTTGCCGACCTGCTGCGCGAGATCATGGCCCGTGATGCCCGTGATGC
GCAACGGGTGGTGGCGCCATTACGGTCGGCCAAAGACGCCGTGCTGATCGATACCAGCGGAATCGGGGTCGAGGATGTCG
TCCAGCGTGTGGTCGGGTTGCTCGCAGACCGCACGCCGTCGTAA

Upstream 100 bases:

>100_bases
CGGCAATTCTAACCGGCTTTTTGTCGTGCTTTCAAGTGGTTGCAGCGCGATCGCGTTGAGCGGCGCTACACTACCGCCTG
ATGATACCCCGGAAACCTGA

Downstream 100 bases:

>100_bases
GTGTTCCGCAAGCGGGCTTGTCCCGCCGACCGTAAGGCGTTCCAAAGCTCCGTCGCGCATCCTGCGCGACGGTTCTACTA
CTCCTAAACCGACTCGCTGT

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTKVEFDDAGEAGLR
VLVNGADVTSELRLETTGALASAIAAIPEVRSALKERQRAFRRAPGLVADGRDMGTVIFPDAAFKVFLTASAEERAGRRH
KQLMEKGVSVTFADLLREIMARDARDAQRVVAPLRSAKDAVLIDTSGIGVEDVVQRVVGLLADRTPS

Sequences:

>Translated_227_residues
MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTKVEFDDAGEAGLR
VLVNGADVTSELRLETTGALASAIAAIPEVRSALKERQRAFRRAPGLVADGRDMGTVIFPDAAFKVFLTASAEERAGRRH
KQLMEKGVSVTFADLLREIMARDARDAQRVVAPLRSAKDAVLIDTSGIGVEDVVQRVVGLLADRTPS
>Mature_226_residues
TDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTKVEFDDAGEAGLRV
LVNGADVTSELRLETTGALASAIAAIPEVRSALKERQRAFRRAPGLVADGRDMGTVIFPDAAFKVFLTASAEERAGRRHK
QLMEKGVSVTFADLLREIMARDARDAQRVVAPLRSAKDAVLIDTSGIGVEDVVQRVVGLLADRTPS

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787139, Length=218, Percent_Identity=51.3761467889908, Blast_Score=214, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003136
- InterPro:   IPR011994 [H]

Pfam domain/function: PF02224 Cytidylate_kin [H]

EC number: =2.7.4.14 [H]

Molecular weight: Translated: 24087; Mature: 23955

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAAL
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEE
VRCTFDTKVEFDDAGEAGLRVLVNGADVTSELRLETTGALASAIAAIPEVRSALKERQRA
EEEECCCEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRRAPGLVADGRDMGTVIFPDAAFKVFLTASAEERAGRRHKQLMEKGVSVTFADLLREIM
HHHCCCCEECCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHH
ARDARDAQRVVAPLRSAKDAVLIDTSGIGVEDVVQRVVGLLADRTPS
HCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAAL
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEE
VRCTFDTKVEFDDAGEAGLRVLVNGADVTSELRLETTGALASAIAAIPEVRSALKERQRA
EEEECCCEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRRAPGLVADGRDMGTVIFPDAAFKVFLTASAEERAGRRHKQLMEKGVSVTFADLLREIM
HHHCCCCEECCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHH
ARDARDAQRVVAPLRSAKDAVLIDTSGIGVEDVVQRVVGLLADRTPS
HCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]