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The map label for this gene is hrcA [H]

Identifier: 84623568

GI number: 84623568

Start: 2108433

End: 2109464

Strand: Direct

Name: hrcA [H]

Synonym: XOO_1911

Alternate gene names: 84623568

Gene position: 2108433-2109464 (Clockwise)

Preceding gene: 84623566

Following gene: 84623569

Centisome position: 42.68

GC content: 67.54

Gene sequence:

>1032_bases
ATGCTCGACCCCCGCACCCGTCAGTTGCTGCGCACCCTGATCGCGCGCTACATCCGCGATGGCGAGCCGGTCGGCTCCAA
GACGCTGGCCCAGCATGCGGGGCTGGATGTCAGCCCGGCCACCATCCGCAATATTCTTGCCGACCTGGAAGACGTGGGCC
TGCTCAGCTCCCCGCATACCTCGGCCGGGCGTGTGCCCACCGCGCATGGCTACCGGGTGTTCGTCGACAGCCTGGTGCAG
ATGCAGCCGCCCGGCGAAGAGGAAGTGCGCCGCCTGCGCGCGGAGCTGGCCAGCGGCAACGGCACCCAATCGTTGCTGGG
CAGCGCCTCGCAGATGCTGTCGGCAATGAGCCATTTCGTCGGCGTGGTCAGCGCGCCGCGGCGTGAGCAGTTCGCGTTCC
GGCATATCGATTTCGTGGCGCTGGACGCCCGTCGTGTGCTGGCGATCCTGGTGTTTGCCGACAACGAAGTGCAAAACCGG
GTGATCGAACCGCGGCGCGCCTACGAGCCGGCCGAGCTGGAACGGGTGGCCAATTACCTCAATGCGCAGTTCGCCGGACG
CGCGCTGGCGGACATCCGTGCCTGCCTGCTGCGCGAGCTGCGCATGGCCAAGAACGAGATGGAGCAACTGATGGCGCACA
GCGTGGACCTGGCCAGCGAGGCGCTGGTGCCGGCCGATGCCGACGACATGGTGATGGCCGGGCAGACCCGGTTGATGGGG
GTGCAGGACCTGTCGGACCTGGACCGTCTGCGCGAACTGTTCGAGGTCTTCGCCAGCAAGCGCGAGATCCTGCAGCTGCT
TGAGCGCACCATCCAGGCGCCGGGCGTGCGCATTTTCATCGGCGAAGAAACCGGCATGGTGTCGCTGGAAGACGTCTCGC
TGGTCACCGCGCCGTACACCGCTCACGGCCAGGTGCTGGGCGTGCTGGGGGTGATCGGGCCCAAACGTATGGCCTACGAC
CGCCTGATTCCGCTGGTGCAGACCGCCGCCGACGTGCTGGGCGCGGCCATGGAGTCTCCCGGCACGCGATAA

Upstream 100 bases:

>100_bases
GAAGGGGCAACCGGGGAATCGGACGCTTGCCATCCCGGGGGCCAGACATTATCTATGCCCAGTCTCACCGGATGATCCCA
TGCGCGCGTCCCAGTCCCCA

Downstream 100 bases:

>100_bases
CCGGCATCGATCGGAACGATCATCATCGCTTGAAACGCGCGCGAGCGCCCATATACGGGGTGACGTTGGGGCGGGCGTTC
CGCTTGCCCGGGAACTGCAC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLDPRTRQLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDVGLLSSPHTSAGRVPTAHGYRVFVDSLVQ
MQPPGEEEVRRLRAELASGNGTQSLLGSASQMLSAMSHFVGVVSAPRREQFAFRHIDFVALDARRVLAILVFADNEVQNR
VIEPRRAYEPAELERVANYLNAQFAGRALADIRACLLRELRMAKNEMEQLMAHSVDLASEALVPADADDMVMAGQTRLMG
VQDLSDLDRLRELFEVFASKREILQLLERTIQAPGVRIFIGEETGMVSLEDVSLVTAPYTAHGQVLGVLGVIGPKRMAYD
RLIPLVQTAADVLGAAMESPGTR

Sequences:

>Translated_343_residues
MLDPRTRQLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDVGLLSSPHTSAGRVPTAHGYRVFVDSLVQ
MQPPGEEEVRRLRAELASGNGTQSLLGSASQMLSAMSHFVGVVSAPRREQFAFRHIDFVALDARRVLAILVFADNEVQNR
VIEPRRAYEPAELERVANYLNAQFAGRALADIRACLLRELRMAKNEMEQLMAHSVDLASEALVPADADDMVMAGQTRLMG
VQDLSDLDRLRELFEVFASKREILQLLERTIQAPGVRIFIGEETGMVSLEDVSLVTAPYTAHGQVLGVLGVIGPKRMAYD
RLIPLVQTAADVLGAAMESPGTR
>Mature_343_residues
MLDPRTRQLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDVGLLSSPHTSAGRVPTAHGYRVFVDSLVQ
MQPPGEEEVRRLRAELASGNGTQSLLGSASQMLSAMSHFVGVVSAPRREQFAFRHIDFVALDARRVLAILVFADNEVQNR
VIEPRRAYEPAELERVANYLNAQFAGRALADIRACLLRELRMAKNEMEQLMAHSVDLASEALVPADADDMVMAGQTRLMG
VQDLSDLDRLRELFEVFASKREILQLLERTIQAPGVRIFIGEETGMVSLEDVSLVTAPYTAHGQVLGVLGVIGPKRMAYD
RLIPLVQTAADVLGAAMESPGTR

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 37615; Mature: 37615

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDPRTRQLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDVGLLSSPHT
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
SAGRVPTAHGYRVFVDSLVQMQPPGEEEVRRLRAELASGNGTQSLLGSASQMLSAMSHFV
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GVVSAPRREQFAFRHIDFVALDARRVLAILVFADNEVQNRVIEPRRAYEPAELERVANYL
HHHCCCCHHHHHHHHHHHHEECHHHHHEEEEECCCHHHHHHCCCHHCCCHHHHHHHHHHH
NAQFAGRALADIRACLLRELRMAKNEMEQLMAHSVDLASEALVPADADDMVMAGQTRLMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHCC
VQDLSDLDRLRELFEVFASKREILQLLERTIQAPGVRIFIGEETGMVSLEDVSLVTAPYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCEEEECCCC
AHGQVLGVLGVIGPKRMAYDRLIPLVQTAADVLGAAMESPGTR
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLDPRTRQLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDVGLLSSPHT
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
SAGRVPTAHGYRVFVDSLVQMQPPGEEEVRRLRAELASGNGTQSLLGSASQMLSAMSHFV
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GVVSAPRREQFAFRHIDFVALDARRVLAILVFADNEVQNRVIEPRRAYEPAELERVANYL
HHHCCCCHHHHHHHHHHHHEECHHHHHEEEEECCCHHHHHHCCCHHCCCHHHHHHHHHHH
NAQFAGRALADIRACLLRELRMAKNEMEQLMAHSVDLASEALVPADADDMVMAGQTRLMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHCC
VQDLSDLDRLRELFEVFASKREILQLLERTIQAPGVRIFIGEETGMVSLEDVSLVTAPYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCEEEECCCC
AHGQVLGVLGVIGPKRMAYDRLIPLVQTAADVLGAAMESPGTR
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]