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The map label for this gene is luxQ [H]

Identifier: 84623384

GI number: 84623384

Start: 1906560

End: 1910210

Strand: Direct

Name: luxQ [H]

Synonym: XOO_1727

Alternate gene names: 84623384

Gene position: 1906560-1910210 (Clockwise)

Preceding gene: 84623383

Following gene: 84623385

Centisome position: 38.59

GC content: 59.46

Gene sequence:

>3651_bases
GTGAGGCGATGCGTGCTTGCTCATGCACGGCGCGGCCTGCACTATGCGGCGACCTGCAGTGAAATTTTTATGTCACGCCT
ACGTTTTTGTCCCGCTTTCGGTCGCAACCTTGCTGCACGGTGGTTGGTTCTATTGATCACCGCGGTGCCCGTGTTTGCCT
CCGCGGCGGTACCAACCACTCCGGTGCCGGTCCAACTCACTGTGGCCGACGGTCTTCCGTCCAATACAGTGAACGACTTT
GCCGAGGACAAAAACGGCTACCTCTGGCTAGCAACTACCGATGGTCTGGCCAGGTTCGATGGTCGTAGTTACCGCATCTG
GCGAATGGAGGACGGGCTGACAGATAACTATGCATGGGCGGTAGGAGTCGATGCCGAAAACAGGCTATGGGTTGGTTTAA
ATGATGGCGGTGTAGGTGTTATGGATCCTAAACGGCGCGCATTCAAACCACTGGAGAGCGCGCAGTTTCCTGAGCTCAGT
CACCTCACAGTGTGGGCGATCGCGCAGACGCCCGATGGCGATCTATGGTTTGGAACATCTAGAAGTGGGCTTTATCGGTT
GCGCCCGGATGGCAGCATGCAGCATTTTATGTTTGTGGCAGATGATGCGCATAGTTTGCCGTCTGACCGAGTGAATGAAT
TACGGGTTACAGCTGAAGGGGCACTTTGGATTGGAAGCAATGGAGGCCTCGCACGATGGAATGGAAGGTCTTTTGATCGT
AAGGCGTTGCCAGGAGACAGTCAGTCTTCCAATGGGCTACGCGTTGATCCCAACGGTGGCTTATGGGTTACCGACAGCAA
TAATCAGCTGTATCGACTGGACTCTGGCGGGAATTTTGCTCCGCATCCTTGGCAGCATGCAAACGACGGCCAGAACGTCA
TAGGCATGTTGTTGCATGATCGAAGCGGGCACTATTGGCTGGATACGATGTCCGGTCTGGGCATCTCGGAAGGCACGCAG
GTCCAGAATGTGCCGATCTACAGCTTGTCGGCACATGGACTGGTCAAGCCGAGTTGGGCAATTGCCTACGAGGATCGCGA
AGGTGGCCTGTGGTTTGCCAGTCTCAGTGGTGGGCTTTGGCATCTGCCGCCCAATTGGAGTACTTTTTCGGTGTTGTCGT
ACCACGTTGACGATCCACAATCGATGGCCAATCCTCTTGTACGAGCAGCGGCAGTATCGGCATCCGGTGGATTATGGATT
GCTGGCACGCGCGGCGCGCTAGAACGCCTGGATCCGGTTACCGGCAAGTTGGAACGTCACCTTCGTCCTATCTCAGGGAC
GCGTTGGCCCACGCGTCTCCTGGAGAGCGGACGTGGCTACGTCTGGATTGGATTGCCAGAATCTCTGGTGCGTTATGACC
CGCGTACCCGACAAAGCAAGCGCTGGCCGCTGTCCACAGAGCACTATGTCGAGGCTGACATGGTGACACCTGACCTCATG
GCCTTGGATGCACGCAGTCAGCTTTGGATTTCCTTGAATAAGATGGGCTTCCAGATTCGTGATGAGGAAGGTCGGCTTAT
TCGTGAAATGGAGCAGGGTAAGCATGGGCTGGATAACTCCAGCGCTTACGATTTAAGGCTGGGTCCCGATGGTCAGATGT
GGCTTGCCAGCACGACTGGCCTACAGCACTGGGATCCAAAAGCAGATGCTTTCGTCATGGTGCAAGGCGCGCCTTCCTCA
ACGAATTATGTGGTCCGTTTCACCGACTCAGGTGTGGTTTGGATCGGACTGATGGGCGAGCTGCGGCGCTATCTCTGGGA
TGGCACGCGACTTACGCATCTGGACACCATTGGCGGAGCGCAGGATTTCCCCATGGTGGCACCGAACGGGCTTGTAGTCG
ATGCCGCGGGCGTGGCCTGGGTGTCGAGTGCGCGCGGTCTGATCAGAGTGGACCCCGCTAGCAAAATGGTCCGGATCTAC
GGTGTGCATGACGGGCTTCCCAATCAAGAATTTCTGGGAGACACGCTTGTCCAAGCAACGGGTGGGCAGATTCTAGGCGG
AACGCCTGATGGTGTTGTGCTGTTTGATCCGGCCAAAATGCGTCCAAGTACGCGCCAGCCACCCCTGTTGATTGAGCGGG
TGGGGGTGCGGCGCGGCGAGCGCGGACTGGATGTGACCGGCGTGGAGCCGCTGCGACTGCAGGACGGCGATCGCGATCTG
CATATCGTCGCGCGCATGCCGACCTTTACGCATTCGGAGTCAACCAGCTATCGCTTTCGTCTCAGCGGCTACGACCCGGA
CTGGATCGACGTCGGGCCCAGTGGTGAGCGCTTGTTCTCGCGCCTGCCGGCCGGTCGTTACACGCTGGAAGTGCAGGGGC
GCACTGCAGACGGTATCTGGTCGGCAAGTCAGACCTTGCGTTTTCAGCTGTTGCCAGCATGGTGGCTGTCGCCGTGGGGT
TTAAGCCTGCTCGCCTTGCTGACGGTGTGCCTGATCGCTGCGGCCACCTTGTTGTACCGCCGTCGGCTGCGTCGCTTGAC
TGCCTGGCAGCTGGCGGTGCACAAACAGGAAGTAGCCGAGCAGGCGTCGTTGGCAAAGACGCGGTTCCTGGCAACACTCG
GCCACGAAGTGCGCACGCCGATGACCGGCGTCCTAGGTATGAGCGAGCTGCTGCTCAAGACGTCGTTGGATATCACGCAG
CGCAGTTACACCGAGTCTATCCGCCGCGCGGGTGCGCATCTGCTGCGGCTGGTCAACGATGCGTTGGATCTGGCCCGCAT
CGAGTCCGGCCGGTTGGAACTGGATCTGCAGCCATTTTCGGTGCGTCAACTCGTGGCCGAAGTCGAAGCGCTGATGGCAC
CGTTGGCGCAAGAGCGCGGCCTGCGTTTCAGCCTGGAAATCGGGCTGCTCGGCGACATCACCGCCAGCGGTGATTCCACC
CGCATCCGGCAGATTTTGCTCAATCTGCTCAATAACGCGATCAAATTCACCGAGCGCGGTGTGGTGGGTTTGAAGTTGAC
CACGCTCGGTTCCTATCAAGGCCTGCGCTTCGAGGTTGCCGATACAGGCCCTGGCATCAACGCCGAACAGAAAGCGCGAT
TGTTCCAGCGCTTCGAGCAGGGCGATGGTGCCAGGACCAACTCACGCTACGGCGGCAGTGGGCTGGGGTTGGCGATCTGC
CAGGAGCTGGCAATGGCAATGGGCGGGCATATCGAAGTGATCAGCCGGCTTGGTGCGGGGACGCGCTTTGTAGTGGATCT
GCCGCTGCACTGGGTCGCCTCCAATGCCCCACTCGACGGCGAGCCAGTGGTTGCCGATACGGCGGTCGAACCGCAGCGCA
TCCTGTTGGTGGAAGATGATCCGACCATTGCCGAAGTCATCGTTGGCCTGCTGCGCGCGCAGGGTCACTCTGTGGTGCAT
GCCCCGCATGGCCTGGCGGCGTTGACCGAGGCGGCCGACAACACCTTCGATCTGGCGTTGCTGGATCTGGATCTGCCCGG
GCTGGATGGTTTCGCGCTGGCGCGGCAACTGCGCGCCTTCGGCTATGAGATGCCGTTGATCGCCGTGACCGCACGCTCCG
ATGAGGTCGCCGAGCCGAATGCACAGGACGCCGGCTTCGACAGTTTTCTGCGCAAGCCACTCACCGGCGATATGCTGGCC
GACACCATCGCCGAGGCGTTGCGGCGTGCACGCCCACGCAACGCTATCTAG

Upstream 100 bases:

>100_bases
CGGTGACCGCGGATTTGCTGGTAGAAGCAATCGCGGCTGCGCGCGAGGCGGCAAATACACGAGCGGTAGTCGCTGATGGC
ACTGCATCGGGCGTACGTGA

Downstream 100 bases:

>100_bases
CCGCCATGGAGACGTGACGTTGCGCTACCGCCACTCGGCAACCGCCTCGACTTCCTTGGGATGCGGCCGCGTCTTGGCCA
GCTGCCAGAAGATCAACGTC

Product: histidine kinase-response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1216; Mature: 1216

Protein sequence:

>1216_residues
MRRCVLAHARRGLHYAATCSEIFMSRLRFCPAFGRNLAARWLVLLITAVPVFASAAVPTTPVPVQLTVADGLPSNTVNDF
AEDKNGYLWLATTDGLARFDGRSYRIWRMEDGLTDNYAWAVGVDAENRLWVGLNDGGVGVMDPKRRAFKPLESAQFPELS
HLTVWAIAQTPDGDLWFGTSRSGLYRLRPDGSMQHFMFVADDAHSLPSDRVNELRVTAEGALWIGSNGGLARWNGRSFDR
KALPGDSQSSNGLRVDPNGGLWVTDSNNQLYRLDSGGNFAPHPWQHANDGQNVIGMLLHDRSGHYWLDTMSGLGISEGTQ
VQNVPIYSLSAHGLVKPSWAIAYEDREGGLWFASLSGGLWHLPPNWSTFSVLSYHVDDPQSMANPLVRAAAVSASGGLWI
AGTRGALERLDPVTGKLERHLRPISGTRWPTRLLESGRGYVWIGLPESLVRYDPRTRQSKRWPLSTEHYVEADMVTPDLM
ALDARSQLWISLNKMGFQIRDEEGRLIREMEQGKHGLDNSSAYDLRLGPDGQMWLASTTGLQHWDPKADAFVMVQGAPSS
TNYVVRFTDSGVVWIGLMGELRRYLWDGTRLTHLDTIGGAQDFPMVAPNGLVVDAAGVAWVSSARGLIRVDPASKMVRIY
GVHDGLPNQEFLGDTLVQATGGQILGGTPDGVVLFDPAKMRPSTRQPPLLIERVGVRRGERGLDVTGVEPLRLQDGDRDL
HIVARMPTFTHSESTSYRFRLSGYDPDWIDVGPSGERLFSRLPAGRYTLEVQGRTADGIWSASQTLRFQLLPAWWLSPWG
LSLLALLTVCLIAAATLLYRRRLRRLTAWQLAVHKQEVAEQASLAKTRFLATLGHEVRTPMTGVLGMSELLLKTSLDITQ
RSYTESIRRAGAHLLRLVNDALDLARIESGRLELDLQPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDST
RIRQILLNLLNNAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQGDGARTNSRYGGSGLGLAIC
QELAMAMGGHIEVISRLGAGTRFVVDLPLHWVASNAPLDGEPVVADTAVEPQRILLVEDDPTIAEVIVGLLRAQGHSVVH
APHGLAALTEAADNTFDLALLDLDLPGLDGFALARQLRAFGYEMPLIAVTARSDEVAEPNAQDAGFDSFLRKPLTGDMLA
DTIAEALRRARPRNAI

Sequences:

>Translated_1216_residues
MRRCVLAHARRGLHYAATCSEIFMSRLRFCPAFGRNLAARWLVLLITAVPVFASAAVPTTPVPVQLTVADGLPSNTVNDF
AEDKNGYLWLATTDGLARFDGRSYRIWRMEDGLTDNYAWAVGVDAENRLWVGLNDGGVGVMDPKRRAFKPLESAQFPELS
HLTVWAIAQTPDGDLWFGTSRSGLYRLRPDGSMQHFMFVADDAHSLPSDRVNELRVTAEGALWIGSNGGLARWNGRSFDR
KALPGDSQSSNGLRVDPNGGLWVTDSNNQLYRLDSGGNFAPHPWQHANDGQNVIGMLLHDRSGHYWLDTMSGLGISEGTQ
VQNVPIYSLSAHGLVKPSWAIAYEDREGGLWFASLSGGLWHLPPNWSTFSVLSYHVDDPQSMANPLVRAAAVSASGGLWI
AGTRGALERLDPVTGKLERHLRPISGTRWPTRLLESGRGYVWIGLPESLVRYDPRTRQSKRWPLSTEHYVEADMVTPDLM
ALDARSQLWISLNKMGFQIRDEEGRLIREMEQGKHGLDNSSAYDLRLGPDGQMWLASTTGLQHWDPKADAFVMVQGAPSS
TNYVVRFTDSGVVWIGLMGELRRYLWDGTRLTHLDTIGGAQDFPMVAPNGLVVDAAGVAWVSSARGLIRVDPASKMVRIY
GVHDGLPNQEFLGDTLVQATGGQILGGTPDGVVLFDPAKMRPSTRQPPLLIERVGVRRGERGLDVTGVEPLRLQDGDRDL
HIVARMPTFTHSESTSYRFRLSGYDPDWIDVGPSGERLFSRLPAGRYTLEVQGRTADGIWSASQTLRFQLLPAWWLSPWG
LSLLALLTVCLIAAATLLYRRRLRRLTAWQLAVHKQEVAEQASLAKTRFLATLGHEVRTPMTGVLGMSELLLKTSLDITQ
RSYTESIRRAGAHLLRLVNDALDLARIESGRLELDLQPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDST
RIRQILLNLLNNAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQGDGARTNSRYGGSGLGLAIC
QELAMAMGGHIEVISRLGAGTRFVVDLPLHWVASNAPLDGEPVVADTAVEPQRILLVEDDPTIAEVIVGLLRAQGHSVVH
APHGLAALTEAADNTFDLALLDLDLPGLDGFALARQLRAFGYEMPLIAVTARSDEVAEPNAQDAGFDSFLRKPLTGDMLA
DTIAEALRRARPRNAI
>Mature_1216_residues
MRRCVLAHARRGLHYAATCSEIFMSRLRFCPAFGRNLAARWLVLLITAVPVFASAAVPTTPVPVQLTVADGLPSNTVNDF
AEDKNGYLWLATTDGLARFDGRSYRIWRMEDGLTDNYAWAVGVDAENRLWVGLNDGGVGVMDPKRRAFKPLESAQFPELS
HLTVWAIAQTPDGDLWFGTSRSGLYRLRPDGSMQHFMFVADDAHSLPSDRVNELRVTAEGALWIGSNGGLARWNGRSFDR
KALPGDSQSSNGLRVDPNGGLWVTDSNNQLYRLDSGGNFAPHPWQHANDGQNVIGMLLHDRSGHYWLDTMSGLGISEGTQ
VQNVPIYSLSAHGLVKPSWAIAYEDREGGLWFASLSGGLWHLPPNWSTFSVLSYHVDDPQSMANPLVRAAAVSASGGLWI
AGTRGALERLDPVTGKLERHLRPISGTRWPTRLLESGRGYVWIGLPESLVRYDPRTRQSKRWPLSTEHYVEADMVTPDLM
ALDARSQLWISLNKMGFQIRDEEGRLIREMEQGKHGLDNSSAYDLRLGPDGQMWLASTTGLQHWDPKADAFVMVQGAPSS
TNYVVRFTDSGVVWIGLMGELRRYLWDGTRLTHLDTIGGAQDFPMVAPNGLVVDAAGVAWVSSARGLIRVDPASKMVRIY
GVHDGLPNQEFLGDTLVQATGGQILGGTPDGVVLFDPAKMRPSTRQPPLLIERVGVRRGERGLDVTGVEPLRLQDGDRDL
HIVARMPTFTHSESTSYRFRLSGYDPDWIDVGPSGERLFSRLPAGRYTLEVQGRTADGIWSASQTLRFQLLPAWWLSPWG
LSLLALLTVCLIAAATLLYRRRLRRLTAWQLAVHKQEVAEQASLAKTRFLATLGHEVRTPMTGVLGMSELLLKTSLDITQ
RSYTESIRRAGAHLLRLVNDALDLARIESGRLELDLQPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDST
RIRQILLNLLNNAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQGDGARTNSRYGGSGLGLAIC
QELAMAMGGHIEVISRLGAGTRFVVDLPLHWVASNAPLDGEPVVADTAVEPQRILLVEDDPTIAEVIVGLLRAQGHSVVH
APHGLAALTEAADNTFDLALLDLDLPGLDGFALARQLRAFGYEMPLIAVTARSDEVAEPNAQDAGFDSFLRKPLTGDMLA
DTIAEALRRARPRNAI

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=365, Percent_Identity=35.8904109589041, Blast_Score=190, Evalue=4e-49,
Organism=Escherichia coli, GI1788713, Length=380, Percent_Identity=31.8421052631579, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI87081816, Length=376, Percent_Identity=35.3723404255319, Blast_Score=176, Evalue=8e-45,
Organism=Escherichia coli, GI1789149, Length=396, Percent_Identity=32.0707070707071, Blast_Score=175, Evalue=2e-44,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=38.2978723404255, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1786912, Length=265, Percent_Identity=30.188679245283, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1786600, Length=258, Percent_Identity=30.2325581395349, Blast_Score=98, Evalue=3e-21,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=30.3030303030303, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1786783, Length=243, Percent_Identity=31.2757201646091, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1788394, Length=124, Percent_Identity=33.0645161290323, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1790436, Length=273, Percent_Identity=27.8388278388278, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=28.448275862069, Blast_Score=74, Evalue=8e-14,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=27.5, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1790860, Length=116, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=210, Percent_Identity=29.5238095238095, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=26.7241379310345, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=222, Percent_Identity=28.8288288288288, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1788545, Length=181, Percent_Identity=30.939226519337, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=151, Percent_Identity=31.1258278145695, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 133604; Mature: 133604

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRCVLAHARRGLHYAATCSEIFMSRLRFCPAFGRNLAARWLVLLITAVPVFASAAVPTT
CCCCHHHHHHCCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVPVQLTVADGLPSNTVNDFAEDKNGYLWLATTDGLARFDGRSYRIWRMEDGLTDNYAWA
CCCEEEEEECCCCCCCHHHHHHCCCCEEEEEECCCHHHCCCCCEEEEEECCCCCCCCEEE
VGVDAENRLWVGLNDGGVGVMDPKRRAFKPLESAQFPELSHLTVWAIAQTPDGDLWFGTS
EECCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEECCC
RSGLYRLRPDGSMQHFMFVADDAHSLPSDRVNELRVTAEGALWIGSNGGLARWNGRSFDR
CCCEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCEEEECCCCCEEECCCCCCCC
KALPGDSQSSNGLRVDPNGGLWVTDSNNQLYRLDSGGNFAPHPWQHANDGQNVIGMLLHD
CCCCCCCCCCCCEEECCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEC
RSGHYWLDTMSGLGISEGTQVQNVPIYSLSAHGLVKPSWAIAYEDREGGLWFASLSGGLW
CCCCEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCEE
HLPPNWSTFSVLSYHVDDPQSMANPLVRAAAVSASGGLWIAGTRGALERLDPVTGKLERH
ECCCCCCEEEEEEEECCCHHHHHHHHHHHHHEECCCCEEEEECCHHHHHCCCHHHHHHHH
LRPISGTRWPTRLLESGRGYVWIGLPESLVRYDPRTRQSKRWPLSTEHYVEADMVTPDLM
CCCCCCCCCHHHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCE
ALDARSQLWISLNKMGFQIRDEEGRLIREMEQGKHGLDNSSAYDLRLGPDGQMWLASTTG
EECCCCEEEEEEECCCEEEECCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCC
LQHWDPKADAFVMVQGAPSSTNYVVRFTDSGVVWIGLMGELRRYLWDGTRLTHLDTIGGA
CCCCCCCCCEEEEEECCCCCCCEEEEEECCCEEEEEEHHHHHHHHHCCCEEEEEECCCCC
QDFPMVAPNGLVVDAAGVAWVSSARGLIRVDPASKMVRIYGVHDGLPNQEFLGDTLVQAT
CCCCEECCCCEEEECCCHHHHHCCCCEEEECCHHCEEEEEEECCCCCCHHHHHHHHHHHC
GGQILGGTPDGVVLFDPAKMRPSTRQPPLLIERVGVRRGERGLDVTGVEPLRLQDGDRDL
CCEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCE
HIVARMPTFTHSESTSYRFRLSGYDPDWIDVGPSGERLFSRLPAGRYTLEVQGRTADGIW
EEEEECCCEECCCCCCEEEEECCCCCCCEECCCCHHHHHHHCCCCCEEEEECCCCCCCCC
SASQTLRFQLLPAWWLSPWGLSLLALLTVCLIAAATLLYRRRLRRLTAWQLAVHKQEVAE
CCCCEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASLAKTRFLATLGHEVRTPMTGVLGMSELLLKTSLDITQRSYTESIRRAGAHLLRLVND
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ALDLARIESGRLELDLQPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDST
HHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCHH
RIRQILLNLLNNAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQ
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHC
GDGARTNSRYGGSGLGLAICQELAMAMGGHIEVISRLGAGTRFVVDLPLHWVASNAPLDG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCEEEEECCCCCCC
EPVVADTAVEPQRILLVEDDPTIAEVIVGLLRAQGHSVVHAPHGLAALTEAADNTFDLAL
CCEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCEEEEE
LDLDLPGLDGFALARQLRAFGYEMPLIAVTARSDEVAEPNAQDAGFDSFLRKPLTGDMLA
EEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCHHHH
DTIAEALRRARPRNAI
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRRCVLAHARRGLHYAATCSEIFMSRLRFCPAFGRNLAARWLVLLITAVPVFASAAVPTT
CCCCHHHHHHCCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVPVQLTVADGLPSNTVNDFAEDKNGYLWLATTDGLARFDGRSYRIWRMEDGLTDNYAWA
CCCEEEEEECCCCCCCHHHHHHCCCCEEEEEECCCHHHCCCCCEEEEEECCCCCCCCEEE
VGVDAENRLWVGLNDGGVGVMDPKRRAFKPLESAQFPELSHLTVWAIAQTPDGDLWFGTS
EECCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEECCC
RSGLYRLRPDGSMQHFMFVADDAHSLPSDRVNELRVTAEGALWIGSNGGLARWNGRSFDR
CCCEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCEEEECCCCCEEECCCCCCCC
KALPGDSQSSNGLRVDPNGGLWVTDSNNQLYRLDSGGNFAPHPWQHANDGQNVIGMLLHD
CCCCCCCCCCCCEEECCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEC
RSGHYWLDTMSGLGISEGTQVQNVPIYSLSAHGLVKPSWAIAYEDREGGLWFASLSGGLW
CCCCEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCEE
HLPPNWSTFSVLSYHVDDPQSMANPLVRAAAVSASGGLWIAGTRGALERLDPVTGKLERH
ECCCCCCEEEEEEEECCCHHHHHHHHHHHHHEECCCCEEEEECCHHHHHCCCHHHHHHHH
LRPISGTRWPTRLLESGRGYVWIGLPESLVRYDPRTRQSKRWPLSTEHYVEADMVTPDLM
CCCCCCCCCHHHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCE
ALDARSQLWISLNKMGFQIRDEEGRLIREMEQGKHGLDNSSAYDLRLGPDGQMWLASTTG
EECCCCEEEEEEECCCEEEECCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCC
LQHWDPKADAFVMVQGAPSSTNYVVRFTDSGVVWIGLMGELRRYLWDGTRLTHLDTIGGA
CCCCCCCCCEEEEEECCCCCCCEEEEEECCCEEEEEEHHHHHHHHHCCCEEEEEECCCCC
QDFPMVAPNGLVVDAAGVAWVSSARGLIRVDPASKMVRIYGVHDGLPNQEFLGDTLVQAT
CCCCEECCCCEEEECCCHHHHHCCCCEEEECCHHCEEEEEEECCCCCCHHHHHHHHHHHC
GGQILGGTPDGVVLFDPAKMRPSTRQPPLLIERVGVRRGERGLDVTGVEPLRLQDGDRDL
CCEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCE
HIVARMPTFTHSESTSYRFRLSGYDPDWIDVGPSGERLFSRLPAGRYTLEVQGRTADGIW
EEEEECCCEECCCCCCEEEEECCCCCCCEECCCCHHHHHHHCCCCCEEEEECCCCCCCCC
SASQTLRFQLLPAWWLSPWGLSLLALLTVCLIAAATLLYRRRLRRLTAWQLAVHKQEVAE
CCCCEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASLAKTRFLATLGHEVRTPMTGVLGMSELLLKTSLDITQRSYTESIRRAGAHLLRLVND
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ALDLARIESGRLELDLQPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDST
HHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCHH
RIRQILLNLLNNAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQ
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHC
GDGARTNSRYGGSGLGLAICQELAMAMGGHIEVISRLGAGTRFVVDLPLHWVASNAPLDG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCEEEEECCCCCCC
EPVVADTAVEPQRILLVEDDPTIAEVIVGLLRAQGHSVVHAPHGLAALTEAADNTFDLAL
CCEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCEEEEE
LDLDLPGLDGFALARQLRAFGYEMPLIAVTARSDEVAEPNAQDAGFDSFLRKPLTGDMLA
EEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCHHHH
DTIAEALRRARPRNAI
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]