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The map label for this gene is luxQ [H]

Identifier: 84623383

GI number: 84623383

Start: 1903000

End: 1906563

Strand: Direct

Name: luxQ [H]

Synonym: XOO_1726

Alternate gene names: 84623383

Gene position: 1903000-1906563 (Clockwise)

Preceding gene: 84623382

Following gene: 84623384

Centisome position: 38.52

GC content: 64.23

Gene sequence:

>3564_bases
ATGACGATGAAGAACGTGCTGTTGTCGGTGCTGGCGGTGCTACTGCTATCGATCGGCCTGGATGCGGCGGCAGTGAATCA
GATCGAGACCCCGCGCATGCGCCGGTTCGGTGCGCCCGAAGGCCTGCCCTCACGCATGGTGCTGGCATTGGCGCAGGACC
GGCAGGGCTTTATCTGGGCGGCGACCGGCGATGGCCTGGCACGCTACGACGGCATCGGGCTGCAGGTATGGCAGCACGAC
CCGCATGTCGCCAGTTCGATCCCGGGCAACGAAGTGGAAACGCTGTTCGTCGATGATCGCGACCGGGTGTGGGTTGGCGT
CAATGGCTCGCCACCGAGCATGCTGGATGCGACGCGCACGGCATTTACGAGGTTTCCCAACGTCGGTGCAGCATGCGATG
GGCAGGTCTGGGCGCTGGCGCAGGCACAAGGTGCGATCTGGATAGGAACCAGTAGCGGCGGACTTTGCCGGCGCGAAGAA
AATGGCCGGGTGACGACGTTCCGTGCTACCCCCGATGCGGCTGATGGACTGCCCAGCAACACCATCATGAGCATGGTGAC
AGATGCACGCGGCCGGCTATGGATCGGCACCGATAGCGGGTTGGTGATGCGCGACGGCGAGCGCTTCGTGCGCATCGCGC
CAGACCGATTGGGCACCACTGTTTTCAAGCTGAGCAAGGATGCCGACGGTACGTTGTGGGTAGGGACCAGCACGGGCTTG
TATAGGGTGACACCGGCTGGTGTGCTGGAGCGTGCGCCTTGGACAGGGGCCGATACCGTACGCGCCGCGACCGTGGTGCA
CGATGTGCACGGCGGCTACTGGATGGGTGCCGCCGACGGGTTCTTTCGGGTGGCGCCCGGGGAAACTGCGCTGCGCGTGA
TGGACGGCGATCGTGGCAGCGGCTTTCTCACCGCCCATAGTGGTGTGCTCGATGTGATGCAGGACCGCCAGGGCGGCCTA
TGGCTCGGGCTGATTTCGCAAGGCATCGCGTATCTCCCGCCGGATTGGCGGCGGTTCTCCACCATTTTTGAAAGCCAAGG
CAAGCCGCTGGAGAGCTTGTATCTGTTCAATACCGCCGCCGATGGCGACAGCTTTTTGGTAACGACCGGCGAAGGTGTGT
ACCGGCTGGGCAATGACGGTGAGCTGGTGCCGGTACTGCACAGCGACATATTGGGGGGCGGTACCGTGCAGTCGGTGCTG
CCCGCTGGGGACGGTGGTCTGTGGATCGCGCTGCGCGATGGCATCACACGGTATACCCCAGCGACTGGGCACAAACGCAA
GCTTGCGATGCAGATTGGTAATTCCGCCACGCATCGGGTGGAGCTGATGACGCCAGGCATCAATGGCGAGTTCTGGATTT
CGATCGTGGGAGGTGGCGTACAGCGCCGTGCTGCGGATGGACGACTGCTGGCCACGTTCCACTTCGGTACCGACCTGAGC
GAAGTCGGCGGCATGGTGCAGCAATTGACGGTGCGGCCAGATGGCACCGTCTGGGTCGCAGCCGGTGACGGTTTGTGGGT
CTGGCAGGGCGAACGTTTTCGCGCAGTGATCGATGACGCCCGTCATGAAGTCTATGCGCTGGCCTTCGTTTCGCCGCATG
AGTTCTGGGTTGGGCGTTCCGGTGCGTTGGAGCGCTATGGGTGGGACGGGCAGCAGGCGCGTCTGCTGGAGCGGATAGGG
CACGAGCAGGGTCTGCCATCCACCGAGATACGTGGCCTGGCATTAGGCGGCACCGACACGGTATGGGTCATAACCTCCCG
TGGTCTGTTCGCTTACAAGTGCGGTCAGCCGCAGGTGCATCGCTTCAGTCAACGCGACGGCTTGCCAGATAGTGAGTTCT
CGATGCGTCCGCCGGCCATTGGTCCCAATGGCCAGGTGCTGGCGTTGACGACCAGCGGCATCGTGTTATTCGATCCATCG
CGGCCGTTTGCACCGGCGCCGCTGGCGCGTCTAGTGATCGAGTCGGTGCAGGTGCGGCGTAACGATGCGGAGCGTCCGCA
GACGATTGCGCACAGGGGGCCGGTGATCCTGCAAGCGCGCGATCGCGATCTGCGCATCAGTGCGCGGCTGTTGTCGTTCG
TCGATCCCGCCTCTGCGCATTACCGCTACCGTGTAAATGGCTACGATGAGCGCTGGGTGGAGGAGGGCGCCAGCGGCGAG
CGCGTGATCTCGCGGCTGCCACCGGGGGATTACCGCATCGACGTGCAGGCGCGTGCCGGCGATGGCGACTGGGTGGCCGC
ACCAGCGCTGCAAGTGGAAGTCCGGCCGCCCTGGTGGTTGAGCATGGCCGCGCAACTGGCGGCGTCAGTGCTATGCATGC
TGCTGCTGTGCCTGGGCATTTGGGCCAGGAAAAAACGCGTGCGGCGACGACAGGAATGGGTGCTGGCGCAGCAACGGCAA
CGGCTTGCCGAGCAGGCATCGATTGCCAAATCGCATTTCCTGGCAACGCTCGGTCACGAAGTGCGCACACCCATGACCGG
CGTGCTGGGCATGAGCGAGCTGCTGCTGGCCACGCCCTTGAATGCCAAGCAGCGCAGCCATGTCGATGCGATCCGCAATG
CCGGCACGCATCTGCTGCGATTGGTCAACGATGCACTGGATCTGGCGCGTATCGAAGCAGGCAAGCTGGAGCTGATGCAA
CAGGCCTTCGATCCCGCGCAGCTCGCGCAGGAGCTGGCCGATTTCATGCATCCCATCGCAGATGCGCGCGGCTTGCGTTT
TCTGTATCGCAATCGGTTTCCCACGCAGCTGGTCGTGCTGGGCGACGCCACGCGGGTGCGTCAGATCCTGATCAACCTGC
TGGGCAACGCGATCAAGTTTGCCGAGCGCGGCGACGTGTCGCTAACCTTGAGCCAGCACGGCGAAACGCTGCGCTTCAAG
GTGCGCGATGCGGGGCCGGGCATCGGATTGGAACAGCAGAAGCGCTTGTTTCAGCGCTTCGAGCAGGGCGAGGGCGCGCG
CACCAGCTCGCGTTACGGCGGCAGCGGACTGGGATTGGCGATCTGTCAGGAGCTTACCGTGGCGATGAAGGGCCGGATCC
GCGTGCGTAGCCGGCTCGGTGTCGGCACTCAGTTCACCGTCGATTTGCCTTTGCCGATCGATCGCTCCGGCACACGTATC
GCCACCGGCCAGGTGCAGGCGCTTGCAGGCGAGCCGCTGCGCATCTTGCTGGTGGAAGATGACCCGACCGTGGCTGAGGT
GATCAGCGGCCTGCTGATCAACCGAGGCCATCGTGTGGTGCATGCCGCGCATGGGCTAGCAGCGTTGGCGGAGGCGGTGG
ACGGTGGTTTCGACGTCGCGCTACTGGATCTGGATCTCCCCTGTCTGGACGGCTTCGCCCTGGCATCGCAACTACGCCAG
CTCGGTCACCGCTTCCCGCTGCTGGCAGTCACGGCACGCGCCGACAGCGCCGCCGAAGCCCAGGCGCTGGCAGCAGGCTT
CGACGGATTCCTGCGCAAGCCGGTGACCGCGGATTTGCTGGTAGAAGCAATCGCGGCTGCGCGCGAGGCGGCAAATACAC
GAGCGGTAGTCGCTGATGGCACTGCATCGGGCGTACGTGAGTGA

Upstream 100 bases:

>100_bases
ACACGCTGCCGGCCACTGTCTGCAACCAATGCGTGCTATTTACCGGGTACAGTGCAGTCCCGACAGGCGCGCGCGTGCAC
ACGCGGCGATGTGGACAAGG

Downstream 100 bases:

>100_bases
GGCGATGCGTGCTTGCTCATGCACGGCGCGGCCTGCACTATGCGGCGACCTGCAGTGAAATTTTTATGTCACGCCTACGT
TTTTGTCCCGCTTTCGGTCG

Product: histidine kinase/response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1187; Mature: 1186

Protein sequence:

>1187_residues
MTMKNVLLSVLAVLLLSIGLDAAAVNQIETPRMRRFGAPEGLPSRMVLALAQDRQGFIWAATGDGLARYDGIGLQVWQHD
PHVASSIPGNEVETLFVDDRDRVWVGVNGSPPSMLDATRTAFTRFPNVGAACDGQVWALAQAQGAIWIGTSSGGLCRREE
NGRVTTFRATPDAADGLPSNTIMSMVTDARGRLWIGTDSGLVMRDGERFVRIAPDRLGTTVFKLSKDADGTLWVGTSTGL
YRVTPAGVLERAPWTGADTVRAATVVHDVHGGYWMGAADGFFRVAPGETALRVMDGDRGSGFLTAHSGVLDVMQDRQGGL
WLGLISQGIAYLPPDWRRFSTIFESQGKPLESLYLFNTAADGDSFLVTTGEGVYRLGNDGELVPVLHSDILGGGTVQSVL
PAGDGGLWIALRDGITRYTPATGHKRKLAMQIGNSATHRVELMTPGINGEFWISIVGGGVQRRAADGRLLATFHFGTDLS
EVGGMVQQLTVRPDGTVWVAAGDGLWVWQGERFRAVIDDARHEVYALAFVSPHEFWVGRSGALERYGWDGQQARLLERIG
HEQGLPSTEIRGLALGGTDTVWVITSRGLFAYKCGQPQVHRFSQRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPS
RPFAPAPLARLVIESVQVRRNDAERPQTIAHRGPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEEGASGE
RVISRLPPGDYRIDVQARAGDGDWVAAPALQVEVRPPWWLSMAAQLAASVLCMLLLCLGIWARKKRVRRRQEWVLAQQRQ
RLAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPLNAKQRSHVDAIRNAGTHLLRLVNDALDLARIEAGKLELMQ
QAFDPAQLAQELADFMHPIADARGLRFLYRNRFPTQLVVLGDATRVRQILINLLGNAIKFAERGDVSLTLSQHGETLRFK
VRDAGPGIGLEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLGVGTQFTVDLPLPIDRSGTRI
ATGQVQALAGEPLRILLVEDDPTVAEVISGLLINRGHRVVHAAHGLAALAEAVDGGFDVALLDLDLPCLDGFALASQLRQ
LGHRFPLLAVTARADSAAEAQALAAGFDGFLRKPVTADLLVEAIAAAREAANTRAVVADGTASGVRE

Sequences:

>Translated_1187_residues
MTMKNVLLSVLAVLLLSIGLDAAAVNQIETPRMRRFGAPEGLPSRMVLALAQDRQGFIWAATGDGLARYDGIGLQVWQHD
PHVASSIPGNEVETLFVDDRDRVWVGVNGSPPSMLDATRTAFTRFPNVGAACDGQVWALAQAQGAIWIGTSSGGLCRREE
NGRVTTFRATPDAADGLPSNTIMSMVTDARGRLWIGTDSGLVMRDGERFVRIAPDRLGTTVFKLSKDADGTLWVGTSTGL
YRVTPAGVLERAPWTGADTVRAATVVHDVHGGYWMGAADGFFRVAPGETALRVMDGDRGSGFLTAHSGVLDVMQDRQGGL
WLGLISQGIAYLPPDWRRFSTIFESQGKPLESLYLFNTAADGDSFLVTTGEGVYRLGNDGELVPVLHSDILGGGTVQSVL
PAGDGGLWIALRDGITRYTPATGHKRKLAMQIGNSATHRVELMTPGINGEFWISIVGGGVQRRAADGRLLATFHFGTDLS
EVGGMVQQLTVRPDGTVWVAAGDGLWVWQGERFRAVIDDARHEVYALAFVSPHEFWVGRSGALERYGWDGQQARLLERIG
HEQGLPSTEIRGLALGGTDTVWVITSRGLFAYKCGQPQVHRFSQRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPS
RPFAPAPLARLVIESVQVRRNDAERPQTIAHRGPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEEGASGE
RVISRLPPGDYRIDVQARAGDGDWVAAPALQVEVRPPWWLSMAAQLAASVLCMLLLCLGIWARKKRVRRRQEWVLAQQRQ
RLAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPLNAKQRSHVDAIRNAGTHLLRLVNDALDLARIEAGKLELMQ
QAFDPAQLAQELADFMHPIADARGLRFLYRNRFPTQLVVLGDATRVRQILINLLGNAIKFAERGDVSLTLSQHGETLRFK
VRDAGPGIGLEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLGVGTQFTVDLPLPIDRSGTRI
ATGQVQALAGEPLRILLVEDDPTVAEVISGLLINRGHRVVHAAHGLAALAEAVDGGFDVALLDLDLPCLDGFALASQLRQ
LGHRFPLLAVTARADSAAEAQALAAGFDGFLRKPVTADLLVEAIAAAREAANTRAVVADGTASGVRE
>Mature_1186_residues
TMKNVLLSVLAVLLLSIGLDAAAVNQIETPRMRRFGAPEGLPSRMVLALAQDRQGFIWAATGDGLARYDGIGLQVWQHDP
HVASSIPGNEVETLFVDDRDRVWVGVNGSPPSMLDATRTAFTRFPNVGAACDGQVWALAQAQGAIWIGTSSGGLCRREEN
GRVTTFRATPDAADGLPSNTIMSMVTDARGRLWIGTDSGLVMRDGERFVRIAPDRLGTTVFKLSKDADGTLWVGTSTGLY
RVTPAGVLERAPWTGADTVRAATVVHDVHGGYWMGAADGFFRVAPGETALRVMDGDRGSGFLTAHSGVLDVMQDRQGGLW
LGLISQGIAYLPPDWRRFSTIFESQGKPLESLYLFNTAADGDSFLVTTGEGVYRLGNDGELVPVLHSDILGGGTVQSVLP
AGDGGLWIALRDGITRYTPATGHKRKLAMQIGNSATHRVELMTPGINGEFWISIVGGGVQRRAADGRLLATFHFGTDLSE
VGGMVQQLTVRPDGTVWVAAGDGLWVWQGERFRAVIDDARHEVYALAFVSPHEFWVGRSGALERYGWDGQQARLLERIGH
EQGLPSTEIRGLALGGTDTVWVITSRGLFAYKCGQPQVHRFSQRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPSR
PFAPAPLARLVIESVQVRRNDAERPQTIAHRGPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEEGASGER
VISRLPPGDYRIDVQARAGDGDWVAAPALQVEVRPPWWLSMAAQLAASVLCMLLLCLGIWARKKRVRRRQEWVLAQQRQR
LAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPLNAKQRSHVDAIRNAGTHLLRLVNDALDLARIEAGKLELMQQ
AFDPAQLAQELADFMHPIADARGLRFLYRNRFPTQLVVLGDATRVRQILINLLGNAIKFAERGDVSLTLSQHGETLRFKV
RDAGPGIGLEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLGVGTQFTVDLPLPIDRSGTRIA
TGQVQALAGEPLRILLVEDDPTVAEVISGLLINRGHRVVHAAHGLAALAEAVDGGFDVALLDLDLPCLDGFALASQLRQL
GHRFPLLAVTARADSAAEAQALAAGFDGFLRKPVTADLLVEAIAAAREAANTRAVVADGTASGVRE

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: COG3292

COG function: function code T; Predicted periplasmic ligand-binding sensor domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=379, Percent_Identity=32.9815303430079, Blast_Score=206, Evalue=9e-54,
Organism=Escherichia coli, GI87081816, Length=393, Percent_Identity=34.6055979643766, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI48994928, Length=368, Percent_Identity=32.6086956521739, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI1789149, Length=401, Percent_Identity=32.4189526184539, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=37.9746835443038, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=30.7377049180328, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=30.4166666666667, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=7e-19,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=31.858407079646, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790436, Length=281, Percent_Identity=27.7580071174377, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=26.2008733624454, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790551, Length=212, Percent_Identity=28.7735849056604, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=234, Percent_Identity=27.3504273504274, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=236, Percent_Identity=27.1186440677966, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=25.764192139738, Blast_Score=63, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=75, Percent_Identity=44, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 128643; Mature: 128512

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMKNVLLSVLAVLLLSIGLDAAAVNQIETPRMRRFGAPEGLPSRMVLALAQDRQGFIWA
CCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHCCCCCCCCHHHHEEEECCCCCEEEE
ATGDGLARYDGIGLQVWQHDPHVASSIPGNEVETLFVDDRDRVWVGVNGSPPSMLDATRT
ECCCCCHHCCCCEEEEEECCCCHHCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHH
AFTRFPNVGAACDGQVWALAQAQGAIWIGTSSGGLCRREENGRVTTFRATPDAADGLPSN
HHHHCCCCCCCCCCCEEEEEECCCEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCH
TIMSMVTDARGRLWIGTDSGLVMRDGERFVRIAPDRLGTTVFKLSKDADGTLWVGTSTGL
HHHHHHHCCCCEEEEECCCCEEEECCCCEEEECCHHHCCEEEEEECCCCCEEEEECCCCE
YRVTPAGVLERAPWTGADTVRAATVVHDVHGGYWMGAADGFFRVAPGETALRVMDGDRGS
EEECCHHHHHCCCCCCCCHHHHHHEEEECCCCEEEECCCCEEEECCCCEEEEEEECCCCC
GFLTAHSGVLDVMQDRQGGLWLGLISQGIAYLPPDWRRFSTIFESQGKPLESLYLFNTAA
EEEEECCCHHHHHHCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHCCCCCCHHEEEEEECC
DGDSFLVTTGEGVYRLGNDGELVPVLHSDILGGGTVQSVLPAGDGGLWIALRDGITRYTP
CCCEEEEECCCCEEEECCCCCEEEEEHHHHCCCCCHHHHCCCCCCCEEEEEECCCCCCCC
ATGHKRKLAMQIGNSATHRVELMTPGINGEFWISIVGGGVQRRAADGRLLATFHFGTDLS
CCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCCEECCCCCEEEEEECCCCHH
EVGGMVQQLTVRPDGTVWVAAGDGLWVWQGERFRAVIDDARHEVYALAFVSPHEFWVGRS
HHCCHHHEEEECCCCEEEEEECCEEEEEECCCHHHHHHHCCCEEEEEEEECCHHHCCCCC
GALERYGWDGQQARLLERIGHEQGLPSTEIRGLALGGTDTVWVITSRGLFAYKCGQPQVH
CCCHHCCCCCHHHHHHHHHCHHCCCCCCCCCEEEECCCCEEEEEECCCEEEEECCCCHHH
RFSQRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPSRPFAPAPLARLVIESVQVRR
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHC
NDAERPQTIAHRGPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEEGASGE
CCCCCCHHHHHCCCEEEEECCCCEEHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCHH
RVISRLPPGDYRIDVQARAGDGDWVAAPALQVEVRPPWWLSMAAQLAASVLCMLLLCLGI
HHHHHCCCCCEEEEEEEECCCCCEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
WARKKRVRRRQEWVLAQQRQRLAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
NAKQRSHVDAIRNAGTHLLRLVNDALDLARIEAGKLELMQQAFDPAQLAQELADFMHPIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DARGLRFLYRNRFPTQLVVLGDATRVRQILINLLGNAIKFAERGDVSLTLSQHGETLRFK
HCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEE
VRDAGPGIGLEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLG
EECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCC
VGTQFTVDLPLPIDRSGTRIATGQVQALAGEPLRILLVEDDPTVAEVISGLLINRGHRVV
CCEEEEEEECCCCCCCCCEEECCCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCEEE
HAAHGLAALAEAVDGGFDVALLDLDLPCLDGFALASQLRQLGHRFPLLAVTARADSAAEA
EHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
QALAAGFDGFLRKPVTADLLVEAIAAAREAANTRAVVADGTASGVRE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TMKNVLLSVLAVLLLSIGLDAAAVNQIETPRMRRFGAPEGLPSRMVLALAQDRQGFIWA
CHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHCCCCCCCCHHHHEEEECCCCCEEEE
ATGDGLARYDGIGLQVWQHDPHVASSIPGNEVETLFVDDRDRVWVGVNGSPPSMLDATRT
ECCCCCHHCCCCEEEEEECCCCHHCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHH
AFTRFPNVGAACDGQVWALAQAQGAIWIGTSSGGLCRREENGRVTTFRATPDAADGLPSN
HHHHCCCCCCCCCCCEEEEEECCCEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCH
TIMSMVTDARGRLWIGTDSGLVMRDGERFVRIAPDRLGTTVFKLSKDADGTLWVGTSTGL
HHHHHHHCCCCEEEEECCCCEEEECCCCEEEECCHHHCCEEEEEECCCCCEEEEECCCCE
YRVTPAGVLERAPWTGADTVRAATVVHDVHGGYWMGAADGFFRVAPGETALRVMDGDRGS
EEECCHHHHHCCCCCCCCHHHHHHEEEECCCCEEEECCCCEEEECCCCEEEEEEECCCCC
GFLTAHSGVLDVMQDRQGGLWLGLISQGIAYLPPDWRRFSTIFESQGKPLESLYLFNTAA
EEEEECCCHHHHHHCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHCCCCCCHHEEEEEECC
DGDSFLVTTGEGVYRLGNDGELVPVLHSDILGGGTVQSVLPAGDGGLWIALRDGITRYTP
CCCEEEEECCCCEEEECCCCCEEEEEHHHHCCCCCHHHHCCCCCCCEEEEEECCCCCCCC
ATGHKRKLAMQIGNSATHRVELMTPGINGEFWISIVGGGVQRRAADGRLLATFHFGTDLS
CCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCCEECCCCCEEEEEECCCCHH
EVGGMVQQLTVRPDGTVWVAAGDGLWVWQGERFRAVIDDARHEVYALAFVSPHEFWVGRS
HHCCHHHEEEECCCCEEEEEECCEEEEEECCCHHHHHHHCCCEEEEEEEECCHHHCCCCC
GALERYGWDGQQARLLERIGHEQGLPSTEIRGLALGGTDTVWVITSRGLFAYKCGQPQVH
CCCHHCCCCCHHHHHHHHHCHHCCCCCCCCCEEEECCCCEEEEEECCCEEEEECCCCHHH
RFSQRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPSRPFAPAPLARLVIESVQVRR
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHC
NDAERPQTIAHRGPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEEGASGE
CCCCCCHHHHHCCCEEEEECCCCEEHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCHH
RVISRLPPGDYRIDVQARAGDGDWVAAPALQVEVRPPWWLSMAAQLAASVLCMLLLCLGI
HHHHHCCCCCEEEEEEEECCCCCEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
WARKKRVRRRQEWVLAQQRQRLAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
NAKQRSHVDAIRNAGTHLLRLVNDALDLARIEAGKLELMQQAFDPAQLAQELADFMHPIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DARGLRFLYRNRFPTQLVVLGDATRVRQILINLLGNAIKFAERGDVSLTLSQHGETLRFK
HCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEE
VRDAGPGIGLEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLG
EECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCC
VGTQFTVDLPLPIDRSGTRIATGQVQALAGEPLRILLVEDDPTVAEVISGLLINRGHRVV
CCEEEEEEECCCCCCCCCEEECCCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCEEE
HAAHGLAALAEAVDGGFDVALLDLDLPCLDGFALASQLRQLGHRFPLLAVTARADSAAEA
EHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
QALAAGFDGFLRKPVTADLLVEAIAAAREAANTRAVVADGTASGVRE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]