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The map label for this gene is sucC [H]

Identifier: 84623133

GI number: 84623133

Start: 1616698

End: 1617867

Strand: Direct

Name: sucC [H]

Synonym: XOO_1476

Alternate gene names: 84623133

Gene position: 1616698-1617867 (Clockwise)

Preceding gene: 84623129

Following gene: 84623134

Centisome position: 32.73

GC content: 61.62

Gene sequence:

>1170_bases
ATGAATTTCCACGAATACCAGTCAAAACAGCTGCTTGCCGAGTACGGCATCCCCGTCCCGTCCGGCAAGGTCGCGGCGAC
ACCGGACGAAGCGGTTGACGTCGCCACTTCCCTGGGCAAGGGTCCTTGGATGGTGAAAGCGCAGATCCACGCGGGTGGCC
GCGGCAAGGCTGGCGGCGTCAAGTTCTGCAAGACCACCGACGACGTGAAGGCCGCAGCAGCCAAGATGCTCGGCACCAAG
ATGTCCACCTACCAGACCGCCGGCGTCGAGCTGCCGATCAACCTGGTGCTGGTGACCACGGCCGGTGAGATCGTCAAGGA
GCTGTACCTGTCGATCCTGGTCGACCGCGGCACCAAGACCATCACCTACATCGCCTCAAGCGAAGGCGGCGTGGAGATCG
AGCAGGTCGCGGCCGAAACGCCGGAGCTGATCCACGCGCTCAACGTCGATTTCGTCGAAGGCGTGCAGGGTTATCACGGT
CGCGATTTCGGCTTCAAGTTGGGCCTCAACGCCAAGCAGGCCGGCCAGTTCGCTAGCATCATGGTGAACTTGTACAAGCT
GTTCAACGAAAAGGACCTGGCGCTGGTTGAAATCAACCCGCTGGCGATCCTGGACGACGGCAACCTGTACGCGCTGGATG
GCAAGTTCGACAGCGACGACAACGCCGCGTTCCGTCAGAAGCAGCTGGTCGCCATGCGCGACAAGACGCAGGAAGACGAG
ACCGAAGTGACCGCCTCGGAGCTGGACATCAACTACGTCACCATGGACGGCAACATCGGTTGCATGGTCAACGGCGCCGG
CCTGGCCATGGCGACCATGGACGTCATCAAGCTCAATGGCGGCGAGCCGGCGAACTTCCTGGACGTGGGCGGCGGTGCGA
ACAAGCAGCGCGTCATCGAAGCGTTCAAGCTGATCCTGTCCTCGGACAAGGTCGAAGGCATCTTCGTCAACATCTTCGGC
GGCATCGTCCGCTGCGACATGATTGCCGAGGGCATCATCGCCGCGGTCAAGGAAGTGGGCGTCAAGGTTCCGGTCGTGGT
GCGCCTGGAAGGCACCAACGTGGAAGAAGGCAAGCAGCTGCTGCGCGATAGCGGCATGGCCATCATCCCGGCCGACAACA
TCAACGACGGCGCCAAGAAAGTCGTTGAAGCTGTCAAGAACGCCGCCTGA

Upstream 100 bases:

>100_bases
CGTGGTCGGCCACAATAGGCGGCCCGTTCGCGTCCCATGACGTGCCGCTCCGGCGGTCTGCGTTGCACGCAGCGGTCGTT
TCCTTTTCCCACGGTGACGC

Downstream 100 bases:

>100_bases
TCCACGACACCGAAGGAATTATCCATGTCCGTTTTGATTAACAAGAACACCAAGGTGATCGTGCAGGGCTTTACCGGCCA
GCAGGGCACCTTCCACGCTA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNFHEYQSKQLLAEYGIPVPSGKVAATPDEAVDVATSLGKGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTK
MSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHG
RDFGFKLGLNAKQAGQFASIMVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFG
GIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA

Sequences:

>Translated_389_residues
MNFHEYQSKQLLAEYGIPVPSGKVAATPDEAVDVATSLGKGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTK
MSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHG
RDFGFKLGLNAKQAGQFASIMVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFG
GIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA
>Mature_389_residues
MNFHEYQSKQLLAEYGIPVPSGKVAATPDEAVDVATSLGKGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTK
MSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHG
RDFGFKLGLNAKQAGQFASIMVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFG
GIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=46.6666666666667, Blast_Score=347, Evalue=8e-96,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.3864229765013, Blast_Score=316, Evalue=2e-86,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=44.6280991735537, Blast_Score=298, Evalue=4e-81,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=58.0310880829015, Blast_Score=446, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=46.0154241645244, Blast_Score=330, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=41.6243654822335, Blast_Score=303, Evalue=7e-83,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=45.3400503778337, Blast_Score=345, Evalue=1e-95,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=45.7142857142857, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=45.7142857142857, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI281361397, Length=388, Percent_Identity=45.8762886597938, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI281361395, Length=388, Percent_Identity=45.8762886597938, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=43.9086294416244, Blast_Score=309, Evalue=2e-84,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41401; Mature: 41401

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFHEYQSKQLLAEYGIPVPSGKVAATPDEAVDVATSLGKGPWMVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KFCKTTDDVKAAAAKMLGTKMSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKT
EEECCCHHHHHHHHHHHHCCHHHEEECCEEEEEEEEEEECHHHHHHHHHHHHHHCCCCEE
ITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHGRDFGFKLGLNAKQAGQFASI
EEEEECCCCCEEHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCCCEEECCCHHHHHHHHHH
MVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
HHHHHHHHCCCCEEEEEECCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCH
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIE
HHEEHHHEEEEEEEECCCEEEEEECCCEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKLILSSDKVEGIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQL
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LRDSGMAIIPADNINDGAKKVVEAVKNAA
HHHCCCEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFHEYQSKQLLAEYGIPVPSGKVAATPDEAVDVATSLGKGPWMVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KFCKTTDDVKAAAAKMLGTKMSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKT
EEECCCHHHHHHHHHHHHCCHHHEEECCEEEEEEEEEEECHHHHHHHHHHHHHHCCCCEE
ITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHGRDFGFKLGLNAKQAGQFASI
EEEEECCCCCEEHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCCCEEECCCHHHHHHHHHH
MVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
HHHHHHHHCCCCEEEEEECCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCH
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIE
HHEEHHHEEEEEEEECCCEEEEEECCCEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKLILSSDKVEGIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQL
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LRDSGMAIIPADNINDGAKKVVEAVKNAA
HHHCCCEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA