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The map label for this gene is pilE [H]

Identifier: 84623125

GI number: 84623125

Start: 1606217

End: 1606642

Strand: Direct

Name: pilE [H]

Synonym: XOO_1468

Alternate gene names: 84623125

Gene position: 1606217-1606642 (Clockwise)

Preceding gene: 84623120

Following gene: 84623126

Centisome position: 32.51

GC content: 58.92

Gene sequence:

>426_bases
ATGAAGAAGCAGCAAGGCTTTACACTTATCGAACTGATGATCGTGGTCGCGATCATCGCCATCCTGGCTGCCATCGCGCT
GCCGGCTTATCAGGACTACACCACTCGTGCCAAGCTCAGTGAAGCGCTGACGATGTCGGCGCCTGCCAAACTTGCGGTAA
CGGAGACTGCATCGTCGCTCGGCGGTGTTGCTAATGTTACTCTCGCGAATTCGGGCTACTCATTCCCGGGTGCCACGAAG
TATGTCAGCAACGTCACCATCGCCGATGGTACGGGCCTAGTCACTGTAACTTCTACCGTGCCGAACGCAGCCGGTACCAT
CCTGCTGACCCCGAAGGATGTCGGTGGCGGCCAGCTGAAGTGGACCTGCTCTTCCGCCATCCTCACCAAGTACCTGCCGG
CGGAGTGCCGTAGCTCGGGCACCTGA

Upstream 100 bases:

>100_bases
GTAATCTGCATATACCGATTTGCACACACGCCCTGCTCGGGTGCACCAAGTGCCCGGGCCGGAGATTTCGATAAACTCAC
AACCTCTGGGGAATGCATCC

Downstream 100 bases:

>100_bases
TAAATTCCGACGAGTAGCTTGTAGAGGCCCCGCGACGCGGGGCTTTTTTTTTCTGGAGGCATATCGTGTTGCGGGGCAAA
CGGGCACTAGTAGGGGCGGC

Product: pilin

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MKKQQGFTLIELMIVVAIIAILAAIALPAYQDYTTRAKLSEALTMSAPAKLAVTETASSLGGVANVTLANSGYSFPGATK
YVSNVTIADGTGLVTVTSTVPNAAGTILLTPKDVGGGQLKWTCSSAILTKYLPAECRSSGT

Sequences:

>Translated_141_residues
MKKQQGFTLIELMIVVAIIAILAAIALPAYQDYTTRAKLSEALTMSAPAKLAVTETASSLGGVANVTLANSGYSFPGATK
YVSNVTIADGTGLVTVTSTVPNAAGTILLTPKDVGGGQLKWTCSSAILTKYLPAECRSSGT
>Mature_141_residues
MKKQQGFTLIELMIVVAIIAILAAIALPAYQDYTTRAKLSEALTMSAPAKLAVTETASSLGGVANVTLANSGYSFPGATK
YVSNVTIADGTGLVTVTSTVPNAAGTILLTPKDVGGGQLKWTCSSAILTKYLPAECRSSGT

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=128, Percent_Identity=39.0625, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 14443; Mature: 14443

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQQGFTLIELMIVVAIIAILAAIALPAYQDYTTRAKLSEALTMSAPAKLAVTETASSL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHC
GGVANVTLANSGYSFPGATKYVSNVTIADGTGLVTVTSTVPNAAGTILLTPKDVGGGQLK
CCEEEEEEECCCCCCCCCHHHHCEEEEECCCCEEEEECCCCCCCCEEEECCCCCCCCEEE
WTCSSAILTKYLPAECRSSGT
EEEHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure
MKKQQGFTLIELMIVVAIIAILAAIALPAYQDYTTRAKLSEALTMSAPAKLAVTETASSL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHC
GGVANVTLANSGYSFPGATKYVSNVTIADGTGLVTVTSTVPNAAGTILLTPKDVGGGQLK
CCEEEEEEECCCCCCCCCHHHHCEEEEECCCCEEEEECCCCCCCCEEEECCCCCCCCEEE
WTCSSAILTKYLPAECRSSGT
EEEHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 9515697 [H]