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The map label for this gene is laaA [H]

Identifier: 84622825

GI number: 84622825

Start: 1276425

End: 1277366

Strand: Direct

Name: laaA [H]

Synonym: XOO_1168

Alternate gene names: 84622825

Gene position: 1276425-1277366 (Clockwise)

Preceding gene: 84622824

Following gene: 84622826

Centisome position: 25.84

GC content: 65.5

Gene sequence:

>942_bases
ATGCAGTGCACCGAAGGGCACGTCGAATTCCGCGGCTATCGCACCTGGTACCGCATTACCGGCGACCTGCGCGCGGACGC
CTGCCCGTTGCTGGTGCTGCATGGCGGCCCCGGCTGCACCCATGACTACCTGGACAGCTTCAAGGATCTGGCGGCCAGCG
GCCGTGCGGTCATTCATTACGACCAGCTCGGCAACGGCAACTCGACCCATCTGCCCAATGCCGATCCAGCTTTCTGGACG
GTCGGGCTCTTTCTGGACGAGCTGCAGACGCTGATCGCCCATCTCGCGCTGTCGCAGTACGCCTTGCTGGGCCAATCCTG
GGGCGGAATGCTGGCGGCCGAGCATGCCGTGCGCCGTCCAGCCGGCCTGCGCGCGCTGGTGATCGCCAATTCGCCAGCGT
CGATGGGCTTGTGGCGGGCCGCTGCATTACGTCTACGTGCGCGTTTGCCCGACGACATCCAGGCTGCGCTGGATGCGCAT
GAAGCTGCCGGTACGCTGGACCACCCGGCCTACCGCGCCGCCAGCCAGGTGTTCTACGCGCAGCACGTCTGTCGCTTGTT
GCCATGGCCTGCCGAGGTGGCGCGCACGTTCGCCGCCGTCGATGCCGACCCGACCGTGTATCACGCCATGAACGGGCCGA
CCGAATTCCACGTGGTGGGCAGTTTGCGCAACTGGAGCATCATCGAACGCCTGCATTGCATCACCGCACCCACGCTGGTG
CTCTCGGGCAAGTACGACGAAGCCACGCCGGAAACCGTCGAGCCGTATGCGCGGTTGATTCCGGATGCGCGCTGGCATGT
GTTCGCCAACTCTAGCCATATGCCGCACGTGGAAGAACGCGTTGCCTGCATGCGCCTGGTCGGCAACTTCCTGGACGATC
AGACGCCGCGGCCCGGTAGGCAGATGGTGCGTTCGTCGGCGCTGGCCAATCGCGCTGTTTGA

Upstream 100 bases:

>100_bases
GGCATCCGAGCGCATTCAAACCTGTGAGATTTGCCAGTTAACGCCAGTCGGCCCGCTCGCTAGGCTCGGGGCACATCATT
GCCGCAGGCAGGCGCAGGTC

Downstream 100 bases:

>100_bases
GTGAGCCAGGTGCGGGTGCGGCTATAGCTGGCGAGCCGACATGCCGCTTTGCGTATCCGTGCCTGCCGCGACGATGTCCC
TTTGGGCAGAGGTCATCAAT

Product: proline imino-peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MQCTEGHVEFRGYRTWYRITGDLRADACPLLVLHGGPGCTHDYLDSFKDLAASGRAVIHYDQLGNGNSTHLPNADPAFWT
VGLFLDELQTLIAHLALSQYALLGQSWGGMLAAEHAVRRPAGLRALVIANSPASMGLWRAAALRLRARLPDDIQAALDAH
EAAGTLDHPAYRAASQVFYAQHVCRLLPWPAEVARTFAAVDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHCITAPTLV
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPRPGRQMVRSSALANRAV

Sequences:

>Translated_313_residues
MQCTEGHVEFRGYRTWYRITGDLRADACPLLVLHGGPGCTHDYLDSFKDLAASGRAVIHYDQLGNGNSTHLPNADPAFWT
VGLFLDELQTLIAHLALSQYALLGQSWGGMLAAEHAVRRPAGLRALVIANSPASMGLWRAAALRLRARLPDDIQAALDAH
EAAGTLDHPAYRAASQVFYAQHVCRLLPWPAEVARTFAAVDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHCITAPTLV
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPRPGRQMVRSSALANRAV
>Mature_313_residues
MQCTEGHVEFRGYRTWYRITGDLRADACPLLVLHGGPGCTHDYLDSFKDLAASGRAVIHYDQLGNGNSTHLPNADPAFWT
VGLFLDELQTLIAHLALSQYALLGQSWGGMLAAEHAVRRPAGLRALVIANSPASMGLWRAAALRLRARLPDDIQAALDAH
EAAGTLDHPAYRAASQVFYAQHVCRLLPWPAEVARTFAAVDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHCITAPTLV
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPRPGRQMVRSSALANRAV

Specific function: Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L- alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not hydrolyze dipeptides and D-prolinam

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005945
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.5.1.101 [H]

Molecular weight: Translated: 34456; Mature: 34456

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCTEGHVEFRGYRTWYRITGDLRADACPLLVLHGGPGCTHDYLDSFKDLAASGRAVIHY
CCCCCCCEEEEEEEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEE
DQLGNGNSTHLPNADPAFWTVGLFLDELQTLIAHLALSQYALLGQSWGGMLAAEHAVRRP
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
AGLRALVIANSPASMGLWRAAALRLRARLPDDIQAALDAHEAAGTLDHPAYRAASQVFYA
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
QHVCRLLPWPAEVARTFAAVDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHCITAPTLV
HHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCEEE
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPRPGR
EECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
QMVRSSALANRAV
HHHHHHHHHHCCC
>Mature Secondary Structure
MQCTEGHVEFRGYRTWYRITGDLRADACPLLVLHGGPGCTHDYLDSFKDLAASGRAVIHY
CCCCCCCEEEEEEEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEE
DQLGNGNSTHLPNADPAFWTVGLFLDELQTLIAHLALSQYALLGQSWGGMLAAEHAVRRP
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
AGLRALVIANSPASMGLWRAAALRLRARLPDDIQAALDAHEAAGTLDHPAYRAASQVFYA
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
QHVCRLLPWPAEVARTFAAVDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHCITAPTLV
HHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCEEE
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPRPGR
EECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
QMVRSSALANRAV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA