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The map label for this gene is pdxH [H]

Identifier: 84622802

GI number: 84622802

Start: 1251257

End: 1251856

Strand: Direct

Name: pdxH [H]

Synonym: XOO_1145

Alternate gene names: 84622802

Gene position: 1251257-1251856 (Clockwise)

Preceding gene: 84622797

Following gene: 84622803

Centisome position: 25.33

GC content: 68.83

Gene sequence:

>600_bases
ATGACCGATCTGTACGCAGAAGCTCTTGCCACCTTCGCCGCGCTGTATGCCGAGGCGCAGAACAGCGCCGAACTCGAAGC
CAGCGCGATGACCCTGGCCACCGCCAACGTGGATGGCCGGCCGAGCGCGCGCACCGTGTTGCTCAAGGCCTTCGACGCGC
GCGGGTTCGTGTTCTACAGCCATCTGGACAGCGCGAAGGGACGCGACCTGCAAACCCACCCGCAGGCGGCGCTGCTGTTC
CTGTGGCGCAGCCTGCGCGAGGCCGGCATCCAGGTGCGTATCGAGGGCGGCGTTCAACTGGTGAGCGCGGACGAATCCGA
TGCCTACTTCGCCTCGCGCCCGCGCATGAGCCAGATCGGCGCCTGGGCCTCGCTGCAATCGCAGACGCTGGGTTCGCGCG
CGGAGTTCGACGCGGCCATCGCCAAAGTCGAGGCGACCTTCGAGGGCCGCGAGGTGCCGCGCCCGGAGGGCTGGGGCGGG
TTCCGGGTGGTGCCGCAGGCGTTCGAGTTCTGGTACGGCGCCAAGTTCCGCCTGCACGAGCGCTGGCGCTACGAGGCCGA
CGCGGCCAGCCATTGGAGCAAGCGGATGCTGTATCCGTGA

Upstream 100 bases:

>100_bases
CAGACCAATCGTGCACGATCCGACGATCCGATCGCGGTGCATAGGCGAAGCGCGGGCGATGCGCCCACAATAGGCGTCCA
TCTGGCTGCCACGCACCGTC

Downstream 100 bases:

>100_bases
GTCCGCAGCCTGGCACAGGGCTTCGAGCCAGCTGAACGGGCGGTTTGCCTCGCTTGCCGCGTGCCCGACTGGCTCGCTTT
CGGCCCTTTCTGCCGGTCAC

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTDLYAEALATFAALYAEAQNSAELEASAMTLATANVDGRPSARTVLLKAFDARGFVFYSHLDSAKGRDLQTHPQAALLF
LWRSLREAGIQVRIEGGVQLVSADESDAYFASRPRMSQIGAWASLQSQTLGSRAEFDAAIAKVEATFEGREVPRPEGWGG
FRVVPQAFEFWYGAKFRLHERWRYEADAASHWSKRMLYP

Sequences:

>Translated_199_residues
MTDLYAEALATFAALYAEAQNSAELEASAMTLATANVDGRPSARTVLLKAFDARGFVFYSHLDSAKGRDLQTHPQAALLF
LWRSLREAGIQVRIEGGVQLVSADESDAYFASRPRMSQIGAWASLQSQTLGSRAEFDAAIAKVEATFEGREVPRPEGWGG
FRVVPQAFEFWYGAKFRLHERWRYEADAASHWSKRMLYP
>Mature_198_residues
TDLYAEALATFAALYAEAQNSAELEASAMTLATANVDGRPSARTVLLKAFDARGFVFYSHLDSAKGRDLQTHPQAALLFL
WRSLREAGIQVRIEGGVQLVSADESDAYFASRPRMSQIGAWASLQSQTLGSRAEFDAAIAKVEATFEGREVPRPEGWGGF
RVVPQAFEFWYGAKFRLHERWRYEADAASHWSKRMLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=176, Percent_Identity=42.0454545454545, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI1787926, Length=185, Percent_Identity=38.9189189189189, Blast_Score=139, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17553712, Length=174, Percent_Identity=37.3563218390805, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319509, Length=185, Percent_Identity=39.4594594594595, Blast_Score=132, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24644901, Length=162, Percent_Identity=45.679012345679, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45551845, Length=162, Percent_Identity=45.679012345679, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 22201; Mature: 22070

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLYAEALATFAALYAEAQNSAELEASAMTLATANVDGRPSARTVLLKAFDARGFVFYS
CCHHHHHHHHHHHHHHHHCCCCCCHHHHEEEEEEECCCCCCCHHEEEEEEECCCCEEEEE
HLDSAKGRDLQTHPQAALLFLWRSLREAGIQVRIEGGVQLVSADESDAYFASRPRMSQIG
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCEECCCCCHHHHH
AWASLQSQTLGSRAEFDAAIAKVEATFEGREVPRPEGWGGFRVVPQAFEFWYGAKFRLHE
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEHH
RWRYEADAASHWSKRMLYP
HHCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TDLYAEALATFAALYAEAQNSAELEASAMTLATANVDGRPSARTVLLKAFDARGFVFYS
CHHHHHHHHHHHHHHHHCCCCCCHHHHEEEEEEECCCCCCCHHEEEEEEECCCCEEEEE
HLDSAKGRDLQTHPQAALLFLWRSLREAGIQVRIEGGVQLVSADESDAYFASRPRMSQIG
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCEECCCCCHHHHH
AWASLQSQTLGSRAEFDAAIAKVEATFEGREVPRPEGWGGFRVVPQAFEFWYGAKFRLHE
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEHH
RWRYEADAASHWSKRMLYP
HHCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]