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The map label for this gene is rspB [C]

Identifier: 84621890

GI number: 84621890

Start: 261283

End: 261873

Strand: Direct

Name: rspB [C]

Synonym: XOO_0233

Alternate gene names: 84621890

Gene position: 261283-261873 (Clockwise)

Preceding gene: 84621889

Following gene: 84621891

Centisome position: 5.29

GC content: 65.31

Gene sequence:

>591_bases
ATGCGCGCAGCCATCCACACCCAGTTCGGCGATCCGGGCAAGGTGCTCGAACTGGGCGAACGACCCACACCACAACCCGG
CAAGGGCCAGGTCCGCATCGCGATGCGGCGCTCGCCCATCCACAACCACGACCTATGGACGGTGCGCGGCAACTACGGCT
ACAAGCCCGCGTTGCCGGCGATCGGCGGTAGCGAAGGGTCGGGCGTGATCGATGTGCTGGGCGAAGGTGTCGAGGGGTTG
CAGGTCGGCCAGCGTGTCGTCGCTGCCGGTGTGCATGAGAGCTGGGCCGAGTATTTTCTGGCCGACGCGACCGGCGTGGT
GCCGCTGCCCGACGCACTCGATGACGACCGCGGGTGCCAGCTCATCGCCATGCCGTTGAGCGCACTGATGCTGATCGAAT
TCCTGCAGGTCAAAAAGGGCGATTGGATCGTGCAGAACACCGCCAACGGTGCGGTCGGCAAGACGGTTGCCATGCTCGCC
GCGGCACGCGGCATCAACGTGATCAACCTGGTGCGCCGCGCCGCAGGTGTGGACGAATTGAACGCGCTGGCCATCGGCAA
TGCGGTGTCGACTGCGCAAGATGGTTGGTAA

Upstream 100 bases:

>100_bases
TTCGCTTCATCGGCCGCTTGCAGCGCTCCCGTTGGCATCGCATCACCTTTCACTATGATCGGCCGCACTGCACCACGGGC
GTCGCCGACAGGAGACTTGC

Downstream 100 bases:

>100_bases
GACGCCGTCCGCGCGCTGGCCGGCGATGCACCGATCGTGCGCGCGATCGAATCGGTTGCCGGCAAGGCGGCAGGCGAGCT
GATGGGCCTGCTTGCCGAAG

Product: hypothetical protein

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MRAAIHTQFGDPGKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPALPAIGGSEGSGVIDVLGEGVEGL
QVGQRVVAAGVHESWAEYFLADATGVVPLPDALDDDRGCQLIAMPLSALMLIEFLQVKKGDWIVQNTANGAVGKTVAMLA
AARGINVINLVRRAAGVDELNALAIGNAVSTAQDGW

Sequences:

>Translated_196_residues
MRAAIHTQFGDPGKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPALPAIGGSEGSGVIDVLGEGVEGL
QVGQRVVAAGVHESWAEYFLADATGVVPLPDALDDDRGCQLIAMPLSALMLIEFLQVKKGDWIVQNTANGAVGKTVAMLA
AARGINVINLVRRAAGVDELNALAIGNAVSTAQDGW
>Mature_196_residues
MRAAIHTQFGDPGKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPALPAIGGSEGSGVIDVLGEGVEGL
QVGQRVVAAGVHESWAEYFLADATGVVPLPDALDDDRGCQLIAMPLSALMLIEFLQVKKGDWIVQNTANGAVGKTVAMLA
AARGINVINLVRRAAGVDELNALAIGNAVSTAQDGW

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI67078404, Length=183, Percent_Identity=32.7868852459016, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI67078406, Length=149, Percent_Identity=32.8859060402685, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI24308257, Length=166, Percent_Identity=30.1204819277108, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194239676, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI194239674, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI13236495, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556000, Length=183, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17536829, Length=183, Percent_Identity=32.2404371584699, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17507255, Length=197, Percent_Identity=29.9492385786802, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45550423, Length=185, Percent_Identity=31.8918918918919, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 20652; Mature: 20652

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAIHTQFGDPGKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPALPA
CCCEEECCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCC
IGGSEGSGVIDVLGEGVEGLQVGQRVVAAGVHESWAEYFLADATGVVPLPDALDDDRGCQ
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
LIAMPLSALMLIEFLQVKKGDWIVQNTANGAVGKTVAMLAAARGINVINLVRRAAGVDEL
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHH
NALAIGNAVSTAQDGW
HHEEECCHHCCCCCCC
>Mature Secondary Structure
MRAAIHTQFGDPGKVLELGERPTPQPGKGQVRIAMRRSPIHNHDLWTVRGNYGYKPALPA
CCCEEECCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCC
IGGSEGSGVIDVLGEGVEGLQVGQRVVAAGVHESWAEYFLADATGVVPLPDALDDDRGCQ
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
LIAMPLSALMLIEFLQVKKGDWIVQNTANGAVGKTVAMLAAARGINVINLVRRAAGVDEL
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHH
NALAIGNAVSTAQDGW
HHEEECCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]