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The map label for this gene is tdcB [H]

Identifier: 84621866

GI number: 84621866

Start: 229186

End: 230145

Strand: Direct

Name: tdcB [H]

Synonym: XOO_0209

Alternate gene names: 84621866

Gene position: 229186-230145 (Clockwise)

Preceding gene: 84621863

Following gene: 84621867

Centisome position: 4.64

GC content: 68.85

Gene sequence:

>960_bases
ATGATCGAGACGGTCCCTCTTGCCCATTCCGACGTTCTGCAAGCCGCTGCGCGGATCGCGCCGCACTGCGCGCCGACACC
ATTGCTGACATCGCACAGCCTGGATGCGCTCAGCGGTGCACGGTTGTTCTTCAAGGCCGAACATCTGCAACGCAGCGGGG
CCTTCAAGTTCCGCGGGGCGTGCAATGCCGTGTGGTCGCTGCCGGACGAGCGGACTGCACATGGGGTAGTGACGCATTCA
TCCGGCAACCACGGCGCGGCGCTGGCGCTGGCCGCACGCACGCGTGGCATGGGTTGCCATGTGGTGGTGCCCGAAGGCGC
GGTGGCGGCCAAGCTGGCCAATATTTCCCGGCATGGCGCCACCTTGTGGCGCTGCGCACCGACCATCGCAGCGCGTGAAC
AGCTATGCGCCGAGGTGCAGGCCAGCAGCGGTGCCACGCTGGTGCACCCGTATACCGATGTCGCGGTCATCGCCGGCCAG
GGGACGGCCACGCTGGAGCTGCTGCATCAAAGCGGTGGCCTGGACGTGCTGGTGGCGCCGGTCGGCGGTGGCGGGTTGGC
GGCCGGTGCCGCGCTGGCGCTGCGCTGCGCACCCGGCTGCGAGCTGGTGCTGGCCGAGCCGGCCGGCGCAGCCGATACCG
CGCGTTCGTTGGCGGCAGGCCAGCGGCTGGTCGATTTTGTGCCGGACACTGTGTGCGATGGTCTGCGCGGCACCTTGGGC
GCGCCCAATTTCGCGCTGCTGCAGCACGCCGGCGCGCAGGTGATCACAGTCGACGATGCCGCGGTCGTCCAGGCGATGCG
GCTGATCTGGCAGTTGCTCAAACAAGTGGTCGAGCCGTCTTCGGTGATCACCCTGGCCGCGGTGCTGGCCGAGCCGGCAC
GGTTTGCCGGGCGCCGGGTGGGCTTGATCCTGTCTGGTGGCAATGTCGATCTGGATGCCTTGCCATGGGCCGCGGCGTGA

Upstream 100 bases:

>100_bases
CTTCATTGTGCAGCAACGCGGCGCTTTGTCATCGATCCAGCCCGCGCGGCGGCAGTGCGTGCGACCCGTGAAGAGGGAGC
GATACGTTAATCTTGCAGGC

Downstream 100 bases:

>100_bases
GCAGCCGTTCGCGCGGGCTCGGCCTGTTGGGCTGGGGTTGGCGGTTGTGCATGCCGGCACTGATCTGGCTGGTGGCGGTG
GCGGGCTGGATCGTGTGGAT

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MIETVPLAHSDVLQAAARIAPHCAPTPLLTSHSLDALSGARLFFKAEHLQRSGAFKFRGACNAVWSLPDERTAHGVVTHS
SGNHGAALALAARTRGMGCHVVVPEGAVAAKLANISRHGATLWRCAPTIAAREQLCAEVQASSGATLVHPYTDVAVIAGQ
GTATLELLHQSGGLDVLVAPVGGGGLAAGAALALRCAPGCELVLAEPAGAADTARSLAAGQRLVDFVPDTVCDGLRGTLG
APNFALLQHAGAQVITVDDAAVVQAMRLIWQLLKQVVEPSSVITLAAVLAEPARFAGRRVGLILSGGNVDLDALPWAAA

Sequences:

>Translated_319_residues
MIETVPLAHSDVLQAAARIAPHCAPTPLLTSHSLDALSGARLFFKAEHLQRSGAFKFRGACNAVWSLPDERTAHGVVTHS
SGNHGAALALAARTRGMGCHVVVPEGAVAAKLANISRHGATLWRCAPTIAAREQLCAEVQASSGATLVHPYTDVAVIAGQ
GTATLELLHQSGGLDVLVAPVGGGGLAAGAALALRCAPGCELVLAEPAGAADTARSLAAGQRLVDFVPDTVCDGLRGTLG
APNFALLQHAGAQVITVDDAAVVQAMRLIWQLLKQVVEPSSVITLAAVLAEPARFAGRRVGLILSGGNVDLDALPWAAA
>Mature_319_residues
MIETVPLAHSDVLQAAARIAPHCAPTPLLTSHSLDALSGARLFFKAEHLQRSGAFKFRGACNAVWSLPDERTAHGVVTHS
SGNHGAALALAARTRGMGCHVVVPEGAVAAKLANISRHGATLWRCAPTIAAREQLCAEVQASSGATLVHPYTDVAVIAGQ
GTATLELLHQSGGLDVLVAPVGGGGLAAGAALALRCAPGCELVLAEPAGAADTARSLAAGQRLVDFVPDTVCDGLRGTLG
APNFALLQHAGAQVITVDDAAVVQAMRLIWQLLKQVVEPSSVITLAAVLAEPARFAGRRVGLILSGGNVDLDALPWAAA

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=319, Percent_Identity=38.2445141065831, Blast_Score=216, Evalue=2e-56,
Organism=Escherichia coli, GI1789505, Length=311, Percent_Identity=28.9389067524116, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790207, Length=299, Percent_Identity=32.1070234113712, Blast_Score=101, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17508781, Length=320, Percent_Identity=35.3125, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71991565, Length=311, Percent_Identity=30.5466237942122, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17537387, Length=315, Percent_Identity=30.7936507936508, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322631, Length=305, Percent_Identity=41.3114754098361, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320930, Length=291, Percent_Identity=29.553264604811, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355833, Length=312, Percent_Identity=29.8076923076923, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 32530; Mature: 32530

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETVPLAHSDVLQAAARIAPHCAPTPLLTSHSLDALSGARLFFKAEHLQRSGAFKFRGA
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHEEEHHHHHHCCCEEECCC
CNAVWSLPDERTAHGVVTHSSGNHGAALALAARTRGMGCHVVVPEGAVAAKLANISRHGA
CHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHCCC
TLWRCAPTIAAREQLCAEVQASSGATLVHPYTDVAVIAGQGTATLELLHQSGGLDVLVAP
CCEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCEEEHEEECCCCCEEEEEE
VGGGGLAAGAALALRCAPGCELVLAEPAGAADTARSLAAGQRLVDFVPDTVCDGLRGTLG
CCCCCHHHHHHEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
APNFALLQHAGAQVITVDDAAVVQAMRLIWQLLKQVVEPSSVITLAAVLAEPARFAGRRV
CCCHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEE
GLILSGGNVDLDALPWAAA
EEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MIETVPLAHSDVLQAAARIAPHCAPTPLLTSHSLDALSGARLFFKAEHLQRSGAFKFRGA
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHEEEHHHHHHCCCEEECCC
CNAVWSLPDERTAHGVVTHSSGNHGAALALAARTRGMGCHVVVPEGAVAAKLANISRHGA
CHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHCCC
TLWRCAPTIAAREQLCAEVQASSGATLVHPYTDVAVIAGQGTATLELLHQSGGLDVLVAP
CCEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCEEEHEEECCCCCEEEEEE
VGGGGLAAGAALALRCAPGCELVLAEPAGAADTARSLAAGQRLVDFVPDTVCDGLRGTLG
CCCCCHHHHHHEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
APNFALLQHAGAQVITVDDAAVVQAMRLIWQLLKQVVEPSSVITLAAVLAEPARFAGRRV
CCCHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEE
GLILSGGNVDLDALPWAAA
EEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA