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The map label for this gene is speA [H]

Identifier: 84621852

GI number: 84621852

Start: 205412

End: 207349

Strand: Direct

Name: speA [H]

Synonym: XOO_0195

Alternate gene names: 84621852

Gene position: 205412-207349 (Clockwise)

Preceding gene: 84621850

Following gene: 84621853

Centisome position: 4.16

GC content: 64.24

Gene sequence:

>1938_bases
ATGCCAGGCGTTACACTTCACGCCCTTTTTTATTCCAGCCGAGACAGCGAAATGAGCGATTGGTCCCTCGACCAAGCCCG
CAAGACCTATTCGATCCCGCATTGGGCCGACGGGTATTTCGATGTGAATGCTGCCGGACACGTGGTGGTCACCCCGACCG
CCGATGGCCCGGCGGTGTCGCTGCCCGAGGTGGTGGATGCCGCGCGCGCGGCCGGCGCCAAGCTGCCGCTGCTGGTGCGT
TTCCCGGACATCCTGGGCCAGCGCCTGGGCAAGCTGCAGGCAGCGTTCGCGCAGGCGCAGTCCGAATGGGATTACGCCGG
CGGCTACACGGCCGTGTATCCGATCAAGGTCAACCAACACCGCGGCGTGGCCGGCACCCTGGCCAGCCATCATGGCGACG
GTTTCGGCCTGGAAGCGGGCAGCAAGCCGGAGCTGATGGCGGTGCTGGCGCTGTCGCGTCCGGGCGGGCTGATCGTCTGC
AACGGCTACAAGGACCGTGAATACATCCGCCTGGCGCTGATCGGGCGCAAGCTCGGCCTGCAGACCTTCATCGTCATCGA
AAAGCCTTCCGAACTGAACTTGGTGTTGGAAGAAGCGCGCGCGCTGGACGTCAAGCCAGGCTTGGGCGTGCGCATGCGCC
TGGCTTCGCTGGGTGCGGGCAAGTGGCAGAACAGTGGGGGCGACAAGGCCAAGTTCGGTCTCTCGCCACGCCAGGTGCTG
GACCTGTGGAAGACGCTGCGCGACACCGAATATGCCGACAGCCTGAATCTGCTGCATTTCCATATGGGCTCGCAGATCTC
CAATGTGCGCGACATCGCCAACGGCATGCGCGAAGCCACGCGCTATTTCGTGGAGCTCTCGCGGCTGGGCGCGAAGATCA
GCCATGTGGATGTGGGCGGCGGCCTGGGCATCGACTACGAAGGCACGCGCTCGCGCAGCTATTGCTCGATCAACTACGGC
CTGCACTCGTACGCCAGCAATATCGTGCAGCCGCTGGCCAGCGCCTGCGAAGAACACGGCCTGGCCCCGCCGCGCATCGT
CACCGAATGCGGGCGCGCGATGACCGCGCACCACGCGGTGCTGATCGCCAACGTCTCGGAAGTGGAGCAGGCGCCCGAAG
GCCGCGTGCCGGACGCGCACGCCGACGAACCGGCGGCGATCCGCCACCTGCGCGAGATCCATGACGAGCTCGATGTGCGC
CCGGCAGTGGAACTGTTCCAGGAAGCGCAGCACTTCCATGCCGAAGGCTTGAGCGCCTATGCACTGGGCCAGATCGACCT
GACCCACCGTGCACGCATCGACGATTTGTTCTATGCCATTGCCCACGGCGTGCGTGCGCGCCTGAGCTTCGACGAGAAGA
GCCATCGCCCGGTGCTGGATGAGCTCAACGAGCGGCTGGTGGACAAGTATTTCGTCAACTTCAGCGTGTTCGAGTCGATC
CCGGATGTGTGGGCGATTGATCAGGTGTTCCCGATCGTGCCGATCGAGCGCTTGAACGAAGCGCCGCAGCGGCGCGGCAT
CATCGCCGACATGACCTGCGATTCCGACGGCATGGTCAAGACCTATGTCGAGAACGAAAGCCTGGACAGCTCGTTGCCGC
TGCACAGCTTGAATGCCGGTGAGAGCTATCGCATCGGCTTCTTCCTGGTCGGTGCCTACCAGGAAATCCTGGGCGATATC
CATAACCTGTTCGGCGATACCGATGCGGTGGAAGTGGCGGTGGATGGCGATGGCTATCGCATCGCGCAGCAGCGCCGCGG
CGATACCACCGACGTGATGGTGGATTACGTGGGCTACCACCTGGATACGCTGCGTGCCACCTATGCCGAGCGCATCGCTG
CCGCGCAACTGCCACCCGAGCGCGCGCAGGAACTCAGCGCTGCGTTGGAAGCGGGCCTGACCGGCTACACCTATCTGTCC
GACGAACCGTTGGGCTGA

Upstream 100 bases:

>100_bases
GCCGCGTGCAGCGAAGCTGCGCAGCGGCTGACCCTTGCTCGGCCCCGATCCAACCAGCAGAGGGGCGTGAAGTCGGCGCG
GATTGTAACGGACCCTGGGC

Downstream 100 bases:

>100_bases
TCTCGCATGCGCTGCGGCTTGTGCCGCAGCGCCGGTGGTGCCAGACGTGGCGCAGCTGCCACGCGTCACTGCCGCGAACG
CCGCTGGACCGTAGGTCAGG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MPGVTLHALFYSSRDSEMSDWSLDQARKTYSIPHWADGYFDVNAAGHVVVTPTADGPAVSLPEVVDAARAAGAKLPLLVR
FPDILGQRLGKLQAAFAQAQSEWDYAGGYTAVYPIKVNQHRGVAGTLASHHGDGFGLEAGSKPELMAVLALSRPGGLIVC
NGYKDREYIRLALIGRKLGLQTFIVIEKPSELNLVLEEARALDVKPGLGVRMRLASLGAGKWQNSGGDKAKFGLSPRQVL
DLWKTLRDTEYADSLNLLHFHMGSQISNVRDIANGMREATRYFVELSRLGAKISHVDVGGGLGIDYEGTRSRSYCSINYG
LHSYASNIVQPLASACEEHGLAPPRIVTECGRAMTAHHAVLIANVSEVEQAPEGRVPDAHADEPAAIRHLREIHDELDVR
PAVELFQEAQHFHAEGLSAYALGQIDLTHRARIDDLFYAIAHGVRARLSFDEKSHRPVLDELNERLVDKYFVNFSVFESI
PDVWAIDQVFPIVPIERLNEAPQRRGIIADMTCDSDGMVKTYVENESLDSSLPLHSLNAGESYRIGFFLVGAYQEILGDI
HNLFGDTDAVEVAVDGDGYRIAQQRRGDTTDVMVDYVGYHLDTLRATYAERIAAAQLPPERAQELSAALEAGLTGYTYLS
DEPLG

Sequences:

>Translated_645_residues
MPGVTLHALFYSSRDSEMSDWSLDQARKTYSIPHWADGYFDVNAAGHVVVTPTADGPAVSLPEVVDAARAAGAKLPLLVR
FPDILGQRLGKLQAAFAQAQSEWDYAGGYTAVYPIKVNQHRGVAGTLASHHGDGFGLEAGSKPELMAVLALSRPGGLIVC
NGYKDREYIRLALIGRKLGLQTFIVIEKPSELNLVLEEARALDVKPGLGVRMRLASLGAGKWQNSGGDKAKFGLSPRQVL
DLWKTLRDTEYADSLNLLHFHMGSQISNVRDIANGMREATRYFVELSRLGAKISHVDVGGGLGIDYEGTRSRSYCSINYG
LHSYASNIVQPLASACEEHGLAPPRIVTECGRAMTAHHAVLIANVSEVEQAPEGRVPDAHADEPAAIRHLREIHDELDVR
PAVELFQEAQHFHAEGLSAYALGQIDLTHRARIDDLFYAIAHGVRARLSFDEKSHRPVLDELNERLVDKYFVNFSVFESI
PDVWAIDQVFPIVPIERLNEAPQRRGIIADMTCDSDGMVKTYVENESLDSSLPLHSLNAGESYRIGFFLVGAYQEILGDI
HNLFGDTDAVEVAVDGDGYRIAQQRRGDTTDVMVDYVGYHLDTLRATYAERIAAAQLPPERAQELSAALEAGLTGYTYLS
DEPLG
>Mature_644_residues
PGVTLHALFYSSRDSEMSDWSLDQARKTYSIPHWADGYFDVNAAGHVVVTPTADGPAVSLPEVVDAARAAGAKLPLLVRF
PDILGQRLGKLQAAFAQAQSEWDYAGGYTAVYPIKVNQHRGVAGTLASHHGDGFGLEAGSKPELMAVLALSRPGGLIVCN
GYKDREYIRLALIGRKLGLQTFIVIEKPSELNLVLEEARALDVKPGLGVRMRLASLGAGKWQNSGGDKAKFGLSPRQVLD
LWKTLRDTEYADSLNLLHFHMGSQISNVRDIANGMREATRYFVELSRLGAKISHVDVGGGLGIDYEGTRSRSYCSINYGL
HSYASNIVQPLASACEEHGLAPPRIVTECGRAMTAHHAVLIANVSEVEQAPEGRVPDAHADEPAAIRHLREIHDELDVRP
AVELFQEAQHFHAEGLSAYALGQIDLTHRARIDDLFYAIAHGVRARLSFDEKSHRPVLDELNERLVDKYFVNFSVFESIP
DVWAIDQVFPIVPIERLNEAPQRRGIIADMTCDSDGMVKTYVENESLDSSLPLHSLNAGESYRIGFFLVGAYQEILGDIH
NLFGDTDAVEVAVDGDGYRIAQQRRGDTTDVMVDYVGYHLDTLRATYAERIAAAQLPPERAQELSAALEAGLTGYTYLSD
EPLG

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=647, Percent_Identity=47.758887171561, Blast_Score=595, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 70708; Mature: 70577

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGVTLHALFYSSRDSEMSDWSLDQARKTYSIPHWADGYFDVNAAGHVVVTPTADGPAVS
CCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCCCCCC
LPEVVDAARAAGAKLPLLVRFPDILGQRLGKLQAAFAQAQSEWDYAGGYTAVYPIKVNQH
CHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
RGVAGTLASHHGDGFGLEAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRKLGL
CCCCHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCHHEEEEEHHHHCCC
QTFIVIEKPSELNLVLEEARALDVKPGLGVRMRLASLGAGKWQNSGGDKAKFGLSPRQVL
EEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCCHHHHH
DLWKTLRDTEYADSLNLLHFHMGSQISNVRDIANGMREATRYFVELSRLGAKISHVDVGG
HHHHHHHCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
GLGIDYEGTRSRSYCSINYGLHSYASNIVQPLASACEEHGLAPPRIVTECGRAMTAHHAV
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEE
LIANVSEVEQAPEGRVPDAHADEPAAIRHLREIHDELDVRPAVELFQEAQHFHAEGLSAY
EEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
ALGQIDLTHRARIDDLFYAIAHGVRARLSFDEKSHRPVLDELNERLVDKYFVNFSVFESI
EEEEEECHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PDVWAIDQVFPIVPIERLNEAPQRRGIIADMTCDSDGMVKTYVENESLDSSLPLHSLNAG
CCHHHHHHHCCCCCHHHHCCCHHHCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCC
ESYRIGFFLVGAYQEILGDIHNLFGDTDAVEVAVDGDGYRIAQQRRGDTTDVMVDYVGYH
CCEEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEHHHHCCCCHHHHHHHHHHH
LDTLRATYAERIAAAQLPPERAQELSAALEAGLTGYTYLSDEPLG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
>Mature Secondary Structure 
PGVTLHALFYSSRDSEMSDWSLDQARKTYSIPHWADGYFDVNAAGHVVVTPTADGPAVS
CCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCCCCCC
LPEVVDAARAAGAKLPLLVRFPDILGQRLGKLQAAFAQAQSEWDYAGGYTAVYPIKVNQH
CHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
RGVAGTLASHHGDGFGLEAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRKLGL
CCCCHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCHHEEEEEHHHHCCC
QTFIVIEKPSELNLVLEEARALDVKPGLGVRMRLASLGAGKWQNSGGDKAKFGLSPRQVL
EEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCCHHHHH
DLWKTLRDTEYADSLNLLHFHMGSQISNVRDIANGMREATRYFVELSRLGAKISHVDVGG
HHHHHHHCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
GLGIDYEGTRSRSYCSINYGLHSYASNIVQPLASACEEHGLAPPRIVTECGRAMTAHHAV
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEE
LIANVSEVEQAPEGRVPDAHADEPAAIRHLREIHDELDVRPAVELFQEAQHFHAEGLSAY
EEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
ALGQIDLTHRARIDDLFYAIAHGVRARLSFDEKSHRPVLDELNERLVDKYFVNFSVFESI
EEEEEECHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PDVWAIDQVFPIVPIERLNEAPQRRGIIADMTCDSDGMVKTYVENESLDSSLPLHSLNAG
CCHHHHHHHCCCCCHHHHCCCHHHCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCC
ESYRIGFFLVGAYQEILGDIHNLFGDTDAVEVAVDGDGYRIAQQRRGDTTDVMVDYVGYH
CCEEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEHHHHCCCCHHHHHHHHHHH
LDTLRATYAERIAAAQLPPERAQELSAALEAGLTGYTYLSDEPLG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]