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The map label for this gene is pol

Identifier: 84490287

GI number: 84490287

Start: 1689458

End: 1691242

Strand: Direct

Name: pol

Synonym: Msp_1507

Alternate gene names: 84490287

Gene position: 1689458-1691242 (Clockwise)

Preceding gene: 84490284

Following gene: 84490288

Centisome position: 95.59

GC content: 28.46

Gene sequence:

>1785_bases
ATGGAAACTAAAACTATAGTTCTAAATGATATTGATTATATAACAAGAGATGAAAAACCAGTAATACGATTATTTGGTAG
AGACTCTAAGACAAATGAAAATGTTATTGCATATGACACAACATTTAAACCATATTTATATATTTTACCAAATAATTTAG
ATGAATGTCTAGTTGAACTACGCCAATTAGGTATAGATGATTTAGAATTAGAAGATAAAATAGATATTGGAGTTAAACGT
GAATATATTAAGGCAACATTAATTCATCCACAAGAAGTTCCAAAATTACGTGATATTATACGTGAACTACCTACTGTTAG
AGAAATAAGAGAATATGATATACCATTTTATAGAAGATATTTAATTGATAAACAAATAACACCAACAAATGTTATAGAAA
TTCATGGAAAAACCCAAGATATGGATTTTGATGTTGATGATGATGTTATTATATTTAAATTAGAAGAAAACCCAATTGAT
ACTAAAGAGATTGTAAATCAGAATAAAATATTAAGTTTTGATATAGAAGTTTATAATGCTGAAGGTATGCCCTCTGCTAA
AAAAGATGCCATTATTATGATGAGTTTATGTGGTAATAATGGTTTTAAAAAGGTTTTATCTACAAAAAAATCAAGTAAAG
ATTTTGTTGAAACATTACCTACTGAAGAGGATATGTTAAAACGATTTGTTGAAATTATTAAAGAAGAAAATCCTGATATG
CTTGTAGGATATAACTCTGATAACTTTGATTTACCATATATTAAAGAAAGAGCAGATACACTTAATATTAAATTGCCTCT
TGGAATTGATAAATCAAGTATTAAATTCATAAAAAGAGGATTTAATAATGCAGGCCTTATAAGAGGCCGTGTACATGTAG
ACTTATACCTTCTTGTAAGGCAATACATGAATTTAGATCGTTACACATTAGAACGTGTATATAAAGAATTATTTGATATT
GAAAAGATAGATGTACCTGGAGATAAGATATTTGAATACTGGGATTCTGACAATGAATTATTAGAGAAATTATTTGATTA
TTCAATGGATGATGCTATTACAACAACAGAAATTGCAGATAAATTAACTCCCCTTACTGTTGCACAAACAAGATTAGTTG
GTCAACCATTATTTGACATTGCACGTATGACTACCGGACAAATGGTTGAATGGTATCTTATATGGAAGGCATTTGAAAAA
AACAACATAATACCAAATAAACCAACTACTAATGAATATACTCAAAGAAGAAGTTCTAAAAAGGTAGCAGGAGGCTATGT
TAAAGAACCTGAAAAAGGATTATTTGAACATATTGCATATCTAGATTTTAAAAGCCTATATCCTTCAGTAATTATTGCTC
AAAATATCTCTCCAGATACTATAACTACTGATGATACGCTAGATGAATCAGAATATCATCTATGTCCAGAATCAGATTAT
AAATTTTTAAAAGAACCAAAAGGTTTTATTCCTTCAATTATTGGTTATATTCTTGATGAAAGACAAAGAATTAAAAAATT
AATGTATGAAGAAACTGTACCTGAACAGAAAAAGGCATATGACTTCGAACAACAAGGACTTAAACGTTTAGCAAATTCAA
TGTTCGGAGCTTATGGATATGCGCGATTTAGATGGTATAAAAAAGAATGTGCTGCTGCCATAACTGCTTGGGGAAGGGAA
TATATTCAAGATGCAATGAAAAAATCAGAAGAATATGGTTTTAAACCAATATATGCAGATACTGATGGATTTTATGCTAC
ATATATTGGTAATTTAGATGATTGA

Upstream 100 bases:

>100_bases
TTTTCTTTAAAGCTTATATTTTTATTATAGTATTTATTAATACTTCTCTTTTATTTGATATAAACTTTTTAATATTCTAT
TTTATAAATAATTAAGTATT

Downstream 100 bases:

>100_bases
AAAAAAATAGATAATTTATAAAATATTTATAAGTTAAAAAATACATAATAATTATTAAAAAAAATATAAAGAGTATATTT
TATGAAGCTTAGTCCTTTAC

Product: putative DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
METKTIVLNDIDYITRDEKPVIRLFGRDSKTNENVIAYDTTFKPYLYILPNNLDECLVELRQLGIDDLELEDKIDIGVKR
EYIKATLIHPQEVPKLRDIIRELPTVREIREYDIPFYRRYLIDKQITPTNVIEIHGKTQDMDFDVDDDVIIFKLEENPID
TKEIVNQNKILSFDIEVYNAEGMPSAKKDAIIMMSLCGNNGFKKVLSTKKSSKDFVETLPTEEDMLKRFVEIIKEENPDM
LVGYNSDNFDLPYIKERADTLNIKLPLGIDKSSIKFIKRGFNNAGLIRGRVHVDLYLLVRQYMNLDRYTLERVYKELFDI
EKIDVPGDKIFEYWDSDNELLEKLFDYSMDDAITTTEIADKLTPLTVAQTRLVGQPLFDIARMTTGQMVEWYLIWKAFEK
NNIIPNKPTTNEYTQRRSSKKVAGGYVKEPEKGLFEHIAYLDFKSLYPSVIIAQNISPDTITTDDTLDESEYHLCPESDY
KFLKEPKGFIPSIIGYILDERQRIKKLMYEETVPEQKKAYDFEQQGLKRLANSMFGAYGYARFRWYKKECAAAITAWGRE
YIQDAMKKSEEYGFKPIYADTDGFYATYIGNLDD

Sequences:

>Translated_594_residues
METKTIVLNDIDYITRDEKPVIRLFGRDSKTNENVIAYDTTFKPYLYILPNNLDECLVELRQLGIDDLELEDKIDIGVKR
EYIKATLIHPQEVPKLRDIIRELPTVREIREYDIPFYRRYLIDKQITPTNVIEIHGKTQDMDFDVDDDVIIFKLEENPID
TKEIVNQNKILSFDIEVYNAEGMPSAKKDAIIMMSLCGNNGFKKVLSTKKSSKDFVETLPTEEDMLKRFVEIIKEENPDM
LVGYNSDNFDLPYIKERADTLNIKLPLGIDKSSIKFIKRGFNNAGLIRGRVHVDLYLLVRQYMNLDRYTLERVYKELFDI
EKIDVPGDKIFEYWDSDNELLEKLFDYSMDDAITTTEIADKLTPLTVAQTRLVGQPLFDIARMTTGQMVEWYLIWKAFEK
NNIIPNKPTTNEYTQRRSSKKVAGGYVKEPEKGLFEHIAYLDFKSLYPSVIIAQNISPDTITTDDTLDESEYHLCPESDY
KFLKEPKGFIPSIIGYILDERQRIKKLMYEETVPEQKKAYDFEQQGLKRLANSMFGAYGYARFRWYKKECAAAITAWGRE
YIQDAMKKSEEYGFKPIYADTDGFYATYIGNLDD
>Mature_594_residues
METKTIVLNDIDYITRDEKPVIRLFGRDSKTNENVIAYDTTFKPYLYILPNNLDECLVELRQLGIDDLELEDKIDIGVKR
EYIKATLIHPQEVPKLRDIIRELPTVREIREYDIPFYRRYLIDKQITPTNVIEIHGKTQDMDFDVDDDVIIFKLEENPID
TKEIVNQNKILSFDIEVYNAEGMPSAKKDAIIMMSLCGNNGFKKVLSTKKSSKDFVETLPTEEDMLKRFVEIIKEENPDM
LVGYNSDNFDLPYIKERADTLNIKLPLGIDKSSIKFIKRGFNNAGLIRGRVHVDLYLLVRQYMNLDRYTLERVYKELFDI
EKIDVPGDKIFEYWDSDNELLEKLFDYSMDDAITTTEIADKLTPLTVAQTRLVGQPLFDIARMTTGQMVEWYLIWKAFEK
NNIIPNKPTTNEYTQRRSSKKVAGGYVKEPEKGLFEHIAYLDFKSLYPSVIIAQNISPDTITTDDTLDESEYHLCPESDY
KFLKEPKGFIPSIIGYILDERQRIKKLMYEETVPEQKKAYDFEQQGLKRLANSMFGAYGYARFRWYKKECAAAITAWGRE
YIQDAMKKSEEYGFKPIYADTDGFYATYIGNLDD

Specific function: Thought To Be Involved In DNA Repair And/Or Mutagenesis. [C]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI156616275, Length=530, Percent_Identity=26.9811320754717, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI106507301, Length=467, Percent_Identity=25.4817987152034, Blast_Score=133, Evalue=6e-31,
Organism=Escherichia coli, GI1786246, Length=388, Percent_Identity=25.5154639175258, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32565317, Length=407, Percent_Identity=30.4668304668305, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17559488, Length=463, Percent_Identity=27.645788336933, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17507143, Length=475, Percent_Identity=23.3684210526316, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320101, Length=663, Percent_Identity=26.395173453997, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6324227, Length=397, Percent_Identity=26.7002518891688, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6325090, Length=417, Percent_Identity=25.1798561151079, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24664937, Length=664, Percent_Identity=27.1084337349398, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24648780, Length=391, Percent_Identity=25.5754475703325, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24649301, Length=359, Percent_Identity=23.6768802228412, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 69352; Mature: 69352

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00018 EF_HAND_1 ; PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKTIVLNDIDYITRDEKPVIRLFGRDSKTNENVIAYDTTFKPYLYILPNNLDECLVEL
CCCCEEEEECCHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHH
RQLGIDDLELEDKIDIGVKREYIKATLIHPQEVPKLRDIIRELPTVREIREYDIPFYRRY
HHCCCCCCCCCCCCCCCCHHHHHHHEECCHHCCHHHHHHHHHCCHHHHHHHCCCHHHHHH
LIDKQITPTNVIEIHGKTQDMDFDVDDDVIIFKLEENPIDTKEIVNQNKILSFDIEVYNA
HHCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHCCCCEEEEEEEEEEC
EGMPSAKKDAIIMMSLCGNNGFKKVLSTKKSSKDFVETLPTEEDMLKRFVEIIKEENPDM
CCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCE
LVGYNSDNFDLPYIKERADTLNIKLPLGIDKSSIKFIKRGFNNAGLIRGRVHVDLYLLVR
EEEECCCCCCCCHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHH
QYMNLDRYTLERVYKELFDIEKIDVPGDKIFEYWDSDNELLEKLFDYSMDDAITTTEIAD
HHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHH
KLTPLTVAQTRLVGQPLFDIARMTTGQMVEWYLIWKAFEKNNIIPNKPTTNEYTQRRSSK
HCCCHHHHHHHHHCCHHHHHHHHHHCHHEEEHHEEEHHHCCCCCCCCCCCHHHHHHHHCC
KVAGGYVKEPEKGLFEHIAYLDFKSLYPSVIIAQNISPDTITTDDTLDESEYHLCPESDY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCH
KFLKEPKGFIPSIIGYILDERQRIKKLMYEETVPEQKKAYDFEQQGLKRLANSMFGAYGY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
ARFRWYKKECAAAITAWGREYIQDAMKKSEEYGFKPIYADTDGFYATYIGNLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCC
>Mature Secondary Structure
METKTIVLNDIDYITRDEKPVIRLFGRDSKTNENVIAYDTTFKPYLYILPNNLDECLVEL
CCCCEEEEECCHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHH
RQLGIDDLELEDKIDIGVKREYIKATLIHPQEVPKLRDIIRELPTVREIREYDIPFYRRY
HHCCCCCCCCCCCCCCCCHHHHHHHEECCHHCCHHHHHHHHHCCHHHHHHHCCCHHHHHH
LIDKQITPTNVIEIHGKTQDMDFDVDDDVIIFKLEENPIDTKEIVNQNKILSFDIEVYNA
HHCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHCCCCEEEEEEEEEEC
EGMPSAKKDAIIMMSLCGNNGFKKVLSTKKSSKDFVETLPTEEDMLKRFVEIIKEENPDM
CCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCE
LVGYNSDNFDLPYIKERADTLNIKLPLGIDKSSIKFIKRGFNNAGLIRGRVHVDLYLLVR
EEEECCCCCCCCHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHH
QYMNLDRYTLERVYKELFDIEKIDVPGDKIFEYWDSDNELLEKLFDYSMDDAITTTEIAD
HHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHH
KLTPLTVAQTRLVGQPLFDIARMTTGQMVEWYLIWKAFEKNNIIPNKPTTNEYTQRRSSK
HCCCHHHHHHHHHCCHHHHHHHHHHCHHEEEHHEEEHHHCCCCCCCCCCCHHHHHHHHCC
KVAGGYVKEPEKGLFEHIAYLDFKSLYPSVIIAQNISPDTITTDDTLDESEYHLCPESDY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCH
KFLKEPKGFIPSIIGYILDERQRIKKLMYEETVPEQKKAYDFEQQGLKRLANSMFGAYGY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
ARFRWYKKECAAAITAWGREYIQDAMKKSEEYGFKPIYADTDGFYATYIGNLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]