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The map label for this gene is rpa [H]

Identifier: 84490268

GI number: 84490268

Start: 1669064

End: 1671445

Strand: Direct

Name: rpa [H]

Synonym: Msp_1487

Alternate gene names: 84490268

Gene position: 1669064-1671445 (Clockwise)

Preceding gene: 84490254

Following gene: 84490269

Centisome position: 94.44

GC content: 29.76

Gene sequence:

>2382_bases
TTGACAGGAGAAAATGAAGACTACATAAAAGAAAGATATCAAGAAGTTAAAGAGAAAGTAACATACAAAGACTTCTTAAA
AGATTTAGAAGATATAAAAATAGAAAATGTTGATGCTCCCTTCCTTACACAACAACAATTAATTGATATGGTTATAGAAA
AATATGCAGAACATGAAAACATACAACAAACACATACAAATCAAATACAACCCATATCTTCACTTATTGAAGGAAATGGA
AATATTAGCATACAAGGAAGATTAATATCTATATCCAACATTAAAACATTTACAACAAAAAAAGGTAGAGAAGGAAAAGT
TGCCAATCTAACAGTAGAAGATAATAGTGGAAAAATACGAGTCGTAATGTGGACAGACAATATGAAATACATGAATCGTA
TAGAAGAAGGAAACATTATAAAAGTAAACAATCTTGAAGTAAGAAAAGGATACACTGGAGATCTTGAAGTACAAATGAAA
AATAACTCATCAATACAAGTTTTACCAGAAGAAGTAGATCCATCCCTACCAAAATATGAAGAAAAAATAACTAATCTATC
AGACATTACTGAAGATGGTGAATACAACATCATAGTAAGAATCAAAAAAATATCAACACTTCGTGAAATTATAAAAGGAG
AAAAAACTCTACAGATAATTACATTAGAAATAATGGATAAAACAGGAACACTTGAATTTACACTATGGAACAAAGATACA
AAACTAGTAGATACATTAGAACTAAAAGAACATGATACTATAAAAATCATAAAAGCAAGAGCACAACAAAGATATGATCA
GATAACATTATCCAATAGTTGGAATGGAAGAATTATAAAAAATGAATACGATGTTCCAGATTTTGAAGAAGAAATCCTAA
AAATAGGCTATGCTGAAGAAAAAGAAGATGTAACAATCATAGGGACAATAACCAAAATCTATGATACAATAACATTCACA
AAAACAGATGGAAATGAAGGACATGTTAGAAGCATAGAAGTAACTGATGAGACAGGATCTATAAGAGTAACACTATGGAA
CAAAGAAACAGAAATTGAAATGAGAAAGGGAGATATCATCAAAATTGAAGGAGGATCCATAGAATTTGATGATTATGCTG
GAGATGGATATAGACTAAATACTGGCTGGAATGCATCAATAACAATTAACCCTGAACTTGATACAAAACTTAGAGAAAAA
CTTGAACTAGTAGATACAATTGGAATAGTAAAAATAGAAAACGTTCTAGATTTAAATGAAGACGAAGGTAGAGAAGTAGA
TGTTGTTGGAAGAATAATTACAACCAATGATACTCGTGAATTTGAAAGAGGAGATGGAAGTAAAGGACAAATAAAAAGTA
TTGAATTAGCTGATGAAACAGGAATTGTAAGAACATCACTTTGGGATGAAAAAGTAGATATCACTGAAAAACTTGGTGAT
GCAATAAAAATAGAAAATGCACGAACAAGGATTGGACAGGGTCAAATGGAACTAAGTGTAGGTAAATCCTCACGAATAAC
AACACCTACAGATGAAGAAATAGTAAACCTACCATCATATGAAAACATTGAACAAGACAGATACAATGATAGAACAATAA
GTCAACTTGAAGAAAATGAAACAAACACAAAACTCAGAGTAAGAATCCTTAACATCAATGAAATAAACACATTTACAAGA
ACAGATGGAAGAGATGGAAGAGTAAGATCAATATATGTTGCTGATGAAACTGGTGAAATACAAGTATCACTCTGGGATGA
TGATACAGAAATAAAATTCACCAAAGGTTCTGCAATCATAATAGAAAATCCAAATATAACACGACAAAACACCAAACTAA
GATTATCTATTGGAAATGGAAGTACAATACGTGCAGCAAGACAAGAAGAAGCTGAAAAAATGCTTTCATTAACTGAAATT
GAAAATAAACTCTATGTTGAAAAATACATTGAAGACATAGAAGAAGATGATCAACATATAAAAATTAAAGGAACCATATC
AGAAATTAATAGTGAAAAAATCATCTATACTATGTGTCCAAATTGTAATATTGGAATAACACAAGATGAAAATGGATATA
TATGTAATGAATGTGGAGAAAAAATAGAAAAACCAAATTATCTAATGATTATATCAACAACATTACAAGATGAAACAGGA
ACTGTTCAAGCAACATTCTTCAGAAAAGATGCAGAAGAACTTATAAGCACAACAACTGAGAAAGTTGTAGCAATATATGA
ACAAACTGGAGATGAATCTGCAATGTCTTCAAAACTTGAAGACATGATTGGACATGAAGTTACAATAATAGCTAATGCAA
ACTTTAATGAATATGATGAAGATATTAGGTTAAATGTAAGACAACTAGTAATAGTAGTATAA

Upstream 100 bases:

>100_bases
TAAAACAAATGCAAATTATAAATATATTATAATATATCTAAATTTTTTATAAATAATAATTATTAAATATTAATATAACT
CCCACATAGGAGGATCTAAA

Downstream 100 bases:

>100_bases
TGATATGAAAATAACAAGGAGAATTTAAATGACAGAATTAGAAGATTTACCAAGTGTAGGAGAAAAAACAGCACAAAAAC
TAAGAGATGCTGGATTTGCA

Product: replication factor A

Products: NA

Alternate protein names: RF-A; RP-A; Replication factor A protein 1; Single-stranded DNA-binding protein; mjaSSB [H]

Number of amino acids: Translated: 793; Mature: 792

Protein sequence:

>793_residues
MTGENEDYIKERYQEVKEKVTYKDFLKDLEDIKIENVDAPFLTQQQLIDMVIEKYAEHENIQQTHTNQIQPISSLIEGNG
NISIQGRLISISNIKTFTTKKGREGKVANLTVEDNSGKIRVVMWTDNMKYMNRIEEGNIIKVNNLEVRKGYTGDLEVQMK
NNSSIQVLPEEVDPSLPKYEEKITNLSDITEDGEYNIIVRIKKISTLREIIKGEKTLQIITLEIMDKTGTLEFTLWNKDT
KLVDTLELKEHDTIKIIKARAQQRYDQITLSNSWNGRIIKNEYDVPDFEEEILKIGYAEEKEDVTIIGTITKIYDTITFT
KTDGNEGHVRSIEVTDETGSIRVTLWNKETEIEMRKGDIIKIEGGSIEFDDYAGDGYRLNTGWNASITINPELDTKLREK
LELVDTIGIVKIENVLDLNEDEGREVDVVGRIITTNDTREFERGDGSKGQIKSIELADETGIVRTSLWDEKVDITEKLGD
AIKIENARTRIGQGQMELSVGKSSRITTPTDEEIVNLPSYENIEQDRYNDRTISQLEENETNTKLRVRILNINEINTFTR
TDGRDGRVRSIYVADETGEIQVSLWDDDTEIKFTKGSAIIIENPNITRQNTKLRLSIGNGSTIRAARQEEAEKMLSLTEI
ENKLYVEKYIEDIEEDDQHIKIKGTISEINSEKIIYTMCPNCNIGITQDENGYICNECGEKIEKPNYLMIISTTLQDETG
TVQATFFRKDAEELISTTTEKVVAIYEQTGDESAMSSKLEDMIGHEVTIIANANFNEYDEDIRLNVRQLVIVV

Sequences:

>Translated_793_residues
MTGENEDYIKERYQEVKEKVTYKDFLKDLEDIKIENVDAPFLTQQQLIDMVIEKYAEHENIQQTHTNQIQPISSLIEGNG
NISIQGRLISISNIKTFTTKKGREGKVANLTVEDNSGKIRVVMWTDNMKYMNRIEEGNIIKVNNLEVRKGYTGDLEVQMK
NNSSIQVLPEEVDPSLPKYEEKITNLSDITEDGEYNIIVRIKKISTLREIIKGEKTLQIITLEIMDKTGTLEFTLWNKDT
KLVDTLELKEHDTIKIIKARAQQRYDQITLSNSWNGRIIKNEYDVPDFEEEILKIGYAEEKEDVTIIGTITKIYDTITFT
KTDGNEGHVRSIEVTDETGSIRVTLWNKETEIEMRKGDIIKIEGGSIEFDDYAGDGYRLNTGWNASITINPELDTKLREK
LELVDTIGIVKIENVLDLNEDEGREVDVVGRIITTNDTREFERGDGSKGQIKSIELADETGIVRTSLWDEKVDITEKLGD
AIKIENARTRIGQGQMELSVGKSSRITTPTDEEIVNLPSYENIEQDRYNDRTISQLEENETNTKLRVRILNINEINTFTR
TDGRDGRVRSIYVADETGEIQVSLWDDDTEIKFTKGSAIIIENPNITRQNTKLRLSIGNGSTIRAARQEEAEKMLSLTEI
ENKLYVEKYIEDIEEDDQHIKIKGTISEINSEKIIYTMCPNCNIGITQDENGYICNECGEKIEKPNYLMIISTTLQDETG
TVQATFFRKDAEELISTTTEKVVAIYEQTGDESAMSSKLEDMIGHEVTIIANANFNEYDEDIRLNVRQLVIVV
>Mature_792_residues
TGENEDYIKERYQEVKEKVTYKDFLKDLEDIKIENVDAPFLTQQQLIDMVIEKYAEHENIQQTHTNQIQPISSLIEGNGN
ISIQGRLISISNIKTFTTKKGREGKVANLTVEDNSGKIRVVMWTDNMKYMNRIEEGNIIKVNNLEVRKGYTGDLEVQMKN
NSSIQVLPEEVDPSLPKYEEKITNLSDITEDGEYNIIVRIKKISTLREIIKGEKTLQIITLEIMDKTGTLEFTLWNKDTK
LVDTLELKEHDTIKIIKARAQQRYDQITLSNSWNGRIIKNEYDVPDFEEEILKIGYAEEKEDVTIIGTITKIYDTITFTK
TDGNEGHVRSIEVTDETGSIRVTLWNKETEIEMRKGDIIKIEGGSIEFDDYAGDGYRLNTGWNASITINPELDTKLREKL
ELVDTIGIVKIENVLDLNEDEGREVDVVGRIITTNDTREFERGDGSKGQIKSIELADETGIVRTSLWDEKVDITEKLGDA
IKIENARTRIGQGQMELSVGKSSRITTPTDEEIVNLPSYENIEQDRYNDRTISQLEENETNTKLRVRILNINEINTFTRT
DGRDGRVRSIYVADETGEIQVSLWDDDTEIKFTKGSAIIIENPNITRQNTKLRLSIGNGSTIRAARQEEAEKMLSLTEIE
NKLYVEKYIEDIEEDDQHIKIKGTISEINSEKIIYTMCPNCNIGITQDENGYICNECGEKIEKPNYLMIISTTLQDETGT
VQATFFRKDAEELISTTTEKVVAIYEQTGDESAMSSKLEDMIGHEVTIIANANFNEYDEDIRLNVRQLVIVV

Specific function: Probably plays an essential for replication of the chromosome, DNA recombination and repair [H]

COG id: COG1599

COG function: function code L; Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 OB DNA-binding domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR013955 [H]

Pfam domain/function: PF08646 Rep_fac-A_C; PF01336 tRNA_anti [H]

EC number: NA

Molecular weight: Translated: 90617; Mature: 90486

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGENEDYIKERYQEVKEKVTYKDFLKDLEDIKIENVDAPFLTQQQLIDMVIEKYAEHEN
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHHHCCCC
IQQTHTNQIQPISSLIEGNGNISIQGRLISISNIKTFTTKKGREGKVANLTVEDNSGKIR
HHHHCCCCCCHHHHHHCCCCCEEEEEEEEEECCEEEEECCCCCCCCEEEEEEECCCCEEE
VVMWTDNMKYMNRIEEGNIIKVNNLEVRKGYTGDLEVQMKNNSSIQVLPEEVDPSLPKYE
EEEEECCHHHHHHCCCCCEEEEECEEEECCCCCCEEEEEECCCCEEEECHHCCCCCCCHH
EKITNLSDITEDGEYNIIVRIKKISTLREIIKGEKTLQIITLEIMDKTGTLEFTLWNKDT
HHHCCHHHCCCCCCEEEEEEEEHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEECCCC
KLVDTLELKEHDTIKIIKARAQQRYDQITLSNSWNGRIIKNEYDVPDFEEEILKIGYAEE
CEEEEEECCCCCEEHHHHHHHHHHHHEEEEECCCCCEEEECCCCCCCHHHHHHHCCCCCC
KEDVTIIGTITKIYDTITFTKTDGNEGHVRSIEVTDETGSIRVTLWNKETEIEMRKGDII
CCCEEEEEEEEHHEEEEEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEECCCEE
KIEGGSIEFDDYAGDGYRLNTGWNASITINPELDTKLREKLELVDTIGIVKIENVLDLNE
EEECCEEEECCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCEEEEEEEECCCC
DEGREVDVVGRIITTNDTREFERGDGSKGQIKSIELADETGIVRTSLWDEKVDITEKLGD
CCCCEEEEEEEEEECCCCHHHHCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHCCC
AIKIENARTRIGQGQMELSVGKSSRITTPTDEEIVNLPSYENIEQDRYNDRTISQLEENE
EEEECCCHHHCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCHHHCCCCHHHHHHHCCC
TNTKLRVRILNINEINTFTRTDGRDGRVRSIYVADETGEIQVSLWDDDTEIKFTKGSAII
CCCEEEEEEEEECCCCCEECCCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEECCCEEE
IENPNITRQNTKLRLSIGNGSTIRAARQEEAEKMLSLTEIENKLYVEKYIEDIEEDDQHI
EECCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
KIKGTISEINSEKIIYTMCPNCNIGITQDENGYICNECGEKIEKPNYLMIISTTLQDETG
EEEEEHHHCCCCEEEEEECCCCCCCEEECCCCEEHHHHHHHHCCCCEEEEEEEEECCCCC
TVQATFFRKDAEELISTTTEKVVAIYEQTGDESAMSSKLEDMIGHEVTIIANANFNEYDE
EEEEEEEHHHHHHHHHHCHHHEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCH
DIRLNVRQLVIVV
HHEEEEEEEEEEC
>Mature Secondary Structure 
TGENEDYIKERYQEVKEKVTYKDFLKDLEDIKIENVDAPFLTQQQLIDMVIEKYAEHEN
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHHHCCCC
IQQTHTNQIQPISSLIEGNGNISIQGRLISISNIKTFTTKKGREGKVANLTVEDNSGKIR
HHHHCCCCCCHHHHHHCCCCCEEEEEEEEEECCEEEEECCCCCCCCEEEEEEECCCCEEE
VVMWTDNMKYMNRIEEGNIIKVNNLEVRKGYTGDLEVQMKNNSSIQVLPEEVDPSLPKYE
EEEEECCHHHHHHCCCCCEEEEECEEEECCCCCCEEEEEECCCCEEEECHHCCCCCCCHH
EKITNLSDITEDGEYNIIVRIKKISTLREIIKGEKTLQIITLEIMDKTGTLEFTLWNKDT
HHHCCHHHCCCCCCEEEEEEEEHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEECCCC
KLVDTLELKEHDTIKIIKARAQQRYDQITLSNSWNGRIIKNEYDVPDFEEEILKIGYAEE
CEEEEEECCCCCEEHHHHHHHHHHHHEEEEECCCCCEEEECCCCCCCHHHHHHHCCCCCC
KEDVTIIGTITKIYDTITFTKTDGNEGHVRSIEVTDETGSIRVTLWNKETEIEMRKGDII
CCCEEEEEEEEHHEEEEEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEECCCEE
KIEGGSIEFDDYAGDGYRLNTGWNASITINPELDTKLREKLELVDTIGIVKIENVLDLNE
EEECCEEEECCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCEEEEEEEECCCC
DEGREVDVVGRIITTNDTREFERGDGSKGQIKSIELADETGIVRTSLWDEKVDITEKLGD
CCCCEEEEEEEEEECCCCHHHHCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHCCC
AIKIENARTRIGQGQMELSVGKSSRITTPTDEEIVNLPSYENIEQDRYNDRTISQLEENE
EEEECCCHHHCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCHHHCCCCHHHHHHHCCC
TNTKLRVRILNINEINTFTRTDGRDGRVRSIYVADETGEIQVSLWDDDTEIKFTKGSAII
CCCEEEEEEEEECCCCCEECCCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEECCCEEE
IENPNITRQNTKLRLSIGNGSTIRAARQEEAEKMLSLTEIENKLYVEKYIEDIEEDDQHI
EECCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
KIKGTISEINSEKIIYTMCPNCNIGITQDENGYICNECGEKIEKPNYLMIISTTLQDETG
EEEEEHHHCCCCEEEEEECCCCCCCEEECCCCEEHHHHHHHHCCCCEEEEEEEEECCCCC
TVQATFFRKDAEELISTTTEKVVAIYEQTGDESAMSSKLEDMIGHEVTIIANANFNEYDE
EEEEEEEHHHHHHHHHHCHHHEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCH
DIRLNVRQLVIVV
HHEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9843941 [H]