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The map label for this gene is trxB [H]

Identifier: 84490195

GI number: 84490195

Start: 1588254

End: 1589159

Strand: Direct

Name: trxB [H]

Synonym: Msp_1413

Alternate gene names: 84490195

Gene position: 1588254-1589159 (Clockwise)

Preceding gene: 84490194

Following gene: 84490196

Centisome position: 89.86

GC content: 31.79

Gene sequence:

>906_bases
ATGTATGATTTAGTAATTATTGGAGCTGGTCCTGCAGGTCTTACAGCGGGAATATATGCTGGTAGAAGTGGACTTAATAC
TATTATTCTTGATGAAAATCAAAGTGGTGGAACAGTTAATGTTGCTCCCCTTATAGAAAATTATCCTGGAATCAATGAAA
TACCTGGTGTTGATTTAGCTCGTAGTATGACAGAGCAAGCAAAGAAATATGTGGATATTAGAGAATTTTCTCTAGTTGAG
AGTATCTCTAAATCTATTGGAGGTACTTTTGAAATAAAAACTACAAATGATATTATAGATACAAGATATATTCTTATTGC
TACAGGTTCCTCATATAAAACATTAGATTGTGTAGGTGTAGATGAATTTGTTGGTCGTGGAGTTTCATACTGTGCTGTTT
GTGATGGTACTTTCTTTGTTAAAAAAGAAGTTCTTGTTATTGGTGGTGGAAATTCTGCTGTAACTGAAGCTTTGTATTTA
AATCGTATAGGTGTTAAATGTAGTTTAGTACATAGAAGAGATAAACTTCGTTGTGATAGTCAATTAGAAAAGGATCTTCA
TAATGCTAACATTAAAATATACTGGAACACACAACTAAAATCTGTTAATGGAAATGACTTTTTAGAGGAAGCAGTATTAT
ATAACAATGAAACTGGTGATGAAACTAAAGTTAAAGTATCTGGAATTTTTATTGCCATTGGATATACACCTAATAATAAA
CTTATAAAGGATTTTGGTATTTCTTGTGATGATTTAGGATATATTGAAGTTGATGAAAATATGAAAACTAGTGTCGATGG
AATATATGCTGCAGGTGATATAACTGGTGGTGTTAAACAGGTTATTGTTGCTGCAGGTCAAGCTGCACAAGCTGTAACAC
ATATTAGTGAATTATTATTGATATAG

Upstream 100 bases:

>100_bases
TACTTTTTTTTATAGAATCCATTTTTTTTAATATAAATTTAAATATAAAATAAAAAGATATATTATTTACTAAATAGGTT
AGTAATTCGGAGTGATTATA

Downstream 100 bases:

>100_bases
TGTTGATGATATGACTTTAACTTCCAAATTATTTCAGGAAATATCCTCTGATTTAAAGAAAGATTTTCCAGAGATTGAGT
CAATAGAACGTGAAAATAAT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MYDLVIIGAGPAGLTAGIYAGRSGLNTIILDENQSGGTVNVAPLIENYPGINEIPGVDLARSMTEQAKKYVDIREFSLVE
SISKSIGGTFEIKTTNDIIDTRYILIATGSSYKTLDCVGVDEFVGRGVSYCAVCDGTFFVKKEVLVIGGGNSAVTEALYL
NRIGVKCSLVHRRDKLRCDSQLEKDLHNANIKIYWNTQLKSVNGNDFLEEAVLYNNETGDETKVKVSGIFIAIGYTPNNK
LIKDFGISCDDLGYIEVDENMKTSVDGIYAAGDITGGVKQVIVAAGQAAQAVTHISELLLI

Sequences:

>Translated_301_residues
MYDLVIIGAGPAGLTAGIYAGRSGLNTIILDENQSGGTVNVAPLIENYPGINEIPGVDLARSMTEQAKKYVDIREFSLVE
SISKSIGGTFEIKTTNDIIDTRYILIATGSSYKTLDCVGVDEFVGRGVSYCAVCDGTFFVKKEVLVIGGGNSAVTEALYL
NRIGVKCSLVHRRDKLRCDSQLEKDLHNANIKIYWNTQLKSVNGNDFLEEAVLYNNETGDETKVKVSGIFIAIGYTPNNK
LIKDFGISCDDLGYIEVDENMKTSVDGIYAAGDITGGVKQVIVAAGQAAQAVTHISELLLI
>Mature_301_residues
MYDLVIIGAGPAGLTAGIYAGRSGLNTIILDENQSGGTVNVAPLIENYPGINEIPGVDLARSMTEQAKKYVDIREFSLVE
SISKSIGGTFEIKTTNDIIDTRYILIATGSSYKTLDCVGVDEFVGRGVSYCAVCDGTFFVKKEVLVIGGGNSAVTEALYL
NRIGVKCSLVHRRDKLRCDSQLEKDLHNANIKIYWNTQLKSVNGNDFLEEAVLYNNETGDETKVKVSGIFIAIGYTPNNK
LIKDFGISCDDLGYIEVDENMKTSVDGIYAAGDITGGVKQVIVAAGQAAQAVTHISELLLI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=302, Percent_Identity=35.0993377483444, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87081763, Length=301, Percent_Identity=32.890365448505, Blast_Score=132, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320560, Length=304, Percent_Identity=34.2105263157895, Blast_Score=149, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6321898, Length=300, Percent_Identity=31, Blast_Score=132, Evalue=9e-32,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 32409; Mature: 32409

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDLVIIGAGPAGLTAGIYAGRSGLNTIILDENQSGGTVNVAPLIENYPGINEIPGVDLA
CEEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCEEEEEEHHHCCCCCCCCCCCHHH
RSMTEQAKKYVDIREFSLVESISKSIGGTFEIKTTNDIIDTRYILIATGSSYKTLDCVGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECH
DEFVGRGVSYCAVCDGTFFVKKEVLVIGGGNSAVTEALYLNRIGVKCSLVHRRDKLRCDS
HHHHCCCCEEEEEECCEEEEEEEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCHH
QLEKDLHNANIKIYWNTQLKSVNGNDFLEEAVLYNNETGDETKVKVSGIFIAIGYTPNNK
HHHHHHHCCEEEEEECCEEEECCCCHHHHHHHHCCCCCCCCEEEEEEEEEEEEEECCCCC
LIKDFGISCDDLGYIEVDENMKTSVDGIYAAGDITGGVKQVIVAAGQAAQAVTHISELLL
CHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHC
I
C
>Mature Secondary Structure
MYDLVIIGAGPAGLTAGIYAGRSGLNTIILDENQSGGTVNVAPLIENYPGINEIPGVDLA
CEEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCEEEEEEHHHCCCCCCCCCCCHHH
RSMTEQAKKYVDIREFSLVESISKSIGGTFEIKTTNDIIDTRYILIATGSSYKTLDCVGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECH
DEFVGRGVSYCAVCDGTFFVKKEVLVIGGGNSAVTEALYLNRIGVKCSLVHRRDKLRCDS
HHHHCCCCEEEEEECCEEEEEEEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCHH
QLEKDLHNANIKIYWNTQLKSVNGNDFLEEAVLYNNETGDETKVKVSGIFIAIGYTPNNK
HHHHHHHCCEEEEEECCEEEECCCCHHHHHHHHCCCCCCCCEEEEEEEEEEEEEECCCCC
LIKDFGISCDDLGYIEVDENMKTSVDGIYAAGDITGGVKQVIVAAGQAAQAVTHISELLL
CHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]