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The map label for this gene is ade

Identifier: 84490096

GI number: 84490096

Start: 1473646

End: 1475274

Strand: Direct

Name: ade

Synonym: Msp_1308

Alternate gene names: 84490096

Gene position: 1473646-1475274 (Clockwise)

Preceding gene: 84490095

Following gene: 84490099

Centisome position: 83.38

GC content: 29.71

Gene sequence:

>1629_bases
ATGTTGATAAAGGGAAATATTTTAAATGTATTTACAGATGAAATATATCCAGGAGAAATTAAAATTGAACATGGAATAAT
TGAATCAATAAAAGAAGTTAATGCCGATTTTAATGATATTATAGTTCCAGGTTTTATTGATGCACATATACATATTGAAA
GTTCAATGTTAACACCGTCACGATTTGCTGAAATAGCTCTAAGACATGGAACAACATCAGTCATTGCAGATCCACATGAA
ATTGCAAATGTCATGGGAATGGATGGTATTGACTATATGATTGATGATGCAAAAAAAACACCATTAAAATATTATTTTAC
TGCACCATCCTGTGTACCAGCAACAAAATTTGAAAAATCAGGTGCTACTATAAGTCCAAACATAATAGACAACCTATTAT
CCAGGCCTGAATTTGTAGCATTAGGTGAAGTGATGGATTATAATGCTGTAATTTCTAATGAAAAAAGTATCTTGGAAAAA
ATAAAAATAGCAAAAAAATATCATAAACCAATTGATGGGCATGCACCATTACTAAGTGGAAAGAATCTACAAAAATATGT
TAAACATGGTGTAATTACAGACCATGAAAGTACCACTAAAAAAGAAGTAGCTGAAAAAAAGAGAATGGGTATGAAGATAA
TGATCCGAGAAGGATCAGAATCTAAAATGCTAGAAAAACTCATTTACTCAAATTGTGATTTTATAGTATCTGATGATCTT
AAACCAGAAGATCTTATTAATGGACATTTAGATAAATGTCTACGTAAAGCTGTTGACTATGGAATGGATCCATACGAAGC
TATAAAACTTGTAACAATAAATCCTGCAGAACATTATAATTTAAATGCTGGAAGTATCAGTCCAGGTAAAAGTGCAGATT
TAGTATTTATAGATAATTTACGTGATTTCACAGTAAAACGTGTAGTTATAAATGGTAATACCATATTTAAAAAACAAAAA
TTATTATTCCGTGCAAATCCACGTCCTATTGATACAACATTACATGTGTCCTTAACTAAACCAGAAGATTTTGATTTAAA
AGCCCAAAATCCTGCACATAAAAGTGCTACTGTTAATTTAATTAATGTATCTGATAACACAATCATTACAAAACAATCCA
GTGCAAAATTAAGTATTCAGAAAAAAACAATTATTCCTTCAGTATTTGAAGATATTTTAAAAATAAGTGTTGTAGATAGG
TATGGTGGAAATACTATTTCAAATGGTTTTGTTAAAGGATTTGGAATTAAAAATGGAGCAATAGCATCTAGTGTAAGTCA
TGATTCACATAATATAATAGTTGTTGGAACTAACAGTGAATACATGTCTCGTGCTACTAATCACTTAATTGAAAATAAGG
GAGGTCTTGCTGCAATATCCAACCAGGCTAAATTAGATGTTACCCTACCAATTGCAGGACTTATGAGTGATAAACCAGCA
AAAGTAGTTGCTAATAATTCAGCAAAATTAAATGAATTAGTAAGTAACATGGGATGTGAATTATCTAGCCCATTTACATC
ATTATCATTTATGGCATTACCTGTTGTACCTGAAGTTAAAATGACAACAAATGGATTGTTTAATGTTAATACACATCAAT
TTATTGATATAATAAAAGAAGAAAAATAA

Upstream 100 bases:

>100_bases
TTTAAGAATAAAATAAAAAAAATATTATATTTCAAAAATAAAACTAAAAATACATTAAAATTCATTATAGAGTTACTATT
AAAAGGGGAGTAAAACAAAA

Downstream 100 bases:

>100_bases
GTTATTCTTCTATAATTTCTTTTTTTAAAAGTTTTAAAGACTGAATATGCTGATTATTTCCCGATTTTTTAATAAAACTA
GATAAATTCTGAAGTTTATT

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MLIKGNILNVFTDEIYPGEIKIEHGIIESIKEVNADFNDIIVPGFIDAHIHIESSMLTPSRFAEIALRHGTTSVIADPHE
IANVMGMDGIDYMIDDAKKTPLKYYFTAPSCVPATKFEKSGATISPNIIDNLLSRPEFVALGEVMDYNAVISNEKSILEK
IKIAKKYHKPIDGHAPLLSGKNLQKYVKHGVITDHESTTKKEVAEKKRMGMKIMIREGSESKMLEKLIYSNCDFIVSDDL
KPEDLINGHLDKCLRKAVDYGMDPYEAIKLVTINPAEHYNLNAGSISPGKSADLVFIDNLRDFTVKRVVINGNTIFKKQK
LLFRANPRPIDTTLHVSLTKPEDFDLKAQNPAHKSATVNLINVSDNTIITKQSSAKLSIQKKTIIPSVFEDILKISVVDR
YGGNTISNGFVKGFGIKNGAIASSVSHDSHNIIVVGTNSEYMSRATNHLIENKGGLAAISNQAKLDVTLPIAGLMSDKPA
KVVANNSAKLNELVSNMGCELSSPFTSLSFMALPVVPEVKMTTNGLFNVNTHQFIDIIKEEK

Sequences:

>Translated_542_residues
MLIKGNILNVFTDEIYPGEIKIEHGIIESIKEVNADFNDIIVPGFIDAHIHIESSMLTPSRFAEIALRHGTTSVIADPHE
IANVMGMDGIDYMIDDAKKTPLKYYFTAPSCVPATKFEKSGATISPNIIDNLLSRPEFVALGEVMDYNAVISNEKSILEK
IKIAKKYHKPIDGHAPLLSGKNLQKYVKHGVITDHESTTKKEVAEKKRMGMKIMIREGSESKMLEKLIYSNCDFIVSDDL
KPEDLINGHLDKCLRKAVDYGMDPYEAIKLVTINPAEHYNLNAGSISPGKSADLVFIDNLRDFTVKRVVINGNTIFKKQK
LLFRANPRPIDTTLHVSLTKPEDFDLKAQNPAHKSATVNLINVSDNTIITKQSSAKLSIQKKTIIPSVFEDILKISVVDR
YGGNTISNGFVKGFGIKNGAIASSVSHDSHNIIVVGTNSEYMSRATNHLIENKGGLAAISNQAKLDVTLPIAGLMSDKPA
KVVANNSAKLNELVSNMGCELSSPFTSLSFMALPVVPEVKMTTNGLFNVNTHQFIDIIKEEK
>Mature_542_residues
MLIKGNILNVFTDEIYPGEIKIEHGIIESIKEVNADFNDIIVPGFIDAHIHIESSMLTPSRFAEIALRHGTTSVIADPHE
IANVMGMDGIDYMIDDAKKTPLKYYFTAPSCVPATKFEKSGATISPNIIDNLLSRPEFVALGEVMDYNAVISNEKSILEK
IKIAKKYHKPIDGHAPLLSGKNLQKYVKHGVITDHESTTKKEVAEKKRMGMKIMIREGSESKMLEKLIYSNCDFIVSDDL
KPEDLINGHLDKCLRKAVDYGMDPYEAIKLVTINPAEHYNLNAGSISPGKSADLVFIDNLRDFTVKRVVINGNTIFKKQK
LLFRANPRPIDTTLHVSLTKPEDFDLKAQNPAHKSATVNLINVSDNTIITKQSSAKLSIQKKTIIPSVFEDILKISVVDR
YGGNTISNGFVKGFGIKNGAIASSVSHDSHNIIVVGTNSEYMSRATNHLIENKGGLAAISNQAKLDVTLPIAGLMSDKPA
KVVANNSAKLNELVSNMGCELSSPFTSLSFMALPVVPEVKMTTNGLFNVNTHQFIDIIKEEK

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=510, Percent_Identity=34.3137254901961, Blast_Score=290, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_METST (Q2NER8)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448328.1
- ProteinModelPortal:   Q2NER8
- SMR:   Q2NER8
- STRING:   Q2NER8
- GeneID:   3855936
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1308
- NMPDR:   fig|339860.6.peg.1255
- eggNOG:   arNOG05049
- HOGENOM:   HBG725357
- OMA:   VGLGEMM
- PhylomeDB:   Q2NER8
- ProtClustDB:   CLSK798019
- BioCyc:   MSTA339860:MSP_1308-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 59674; Mature: 59674

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKGNILNVFTDEIYPGEIKIEHGIIESIKEVNADFNDIIVPGFIDAHIHIESSMLTPS
CEEECCEEEEEECCCCCCEEEECHHHHHHHHHHCCCCCCEEECCEEEEEEEEECCCCCHH
RFAEIALRHGTTSVIADPHEIANVMGMDGIDYMIDDAKKTPLKYYFTAPSCVPATKFEKS
HHHHHHHHCCCCEEEECHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCC
GATISPNIIDNLLSRPEFVALGEVMDYNAVISNEKSILEKIKIAKKYHKPIDGHAPLLSG
CCEECHHHHHHHHCCCCEEEECCHHCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
KNLQKYVKHGVITDHESTTKKEVAEKKRMGMKIMIREGSESKMLEKLIYSNCDFIVSDDL
CCHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEEECCC
KPEDLINGHLDKCLRKAVDYGMDPYEAIKLVTINPAEHYNLNAGSISPGKSADLVFIDNL
CHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCHHHCCCCCCCCCCCCCCCEEEECCC
RDFTVKRVVINGNTIFKKQKLLFRANPRPIDTTLHVSLTKPEDFDLKAQNPAHKSATVNL
CCCEEEEEEECCCEEEEEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEE
INVSDNTIITKQSSAKLSIQKKTIIPSVFEDILKISVVDRYGGNTISNGFVKGFGIKNGA
EEECCCEEEEECCCCEEEEEHHHCCHHHHHHHHHEEEEECCCCCCCCCCCEEEECCCCCC
IASSVSHDSHNIIVVGTNSEYMSRATNHLIENKGGLAAISNQAKLDVTLPIAGLMSDKPA
EEECCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEHHCCCCCCC
KVVANNSAKLNELVSNMGCELSSPFTSLSFMALPVVPEVKMTTNGLFNVNTHQFIDIIKE
EEEECCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEECCCCEEECCHHHHHHHHHC
EK
CC
>Mature Secondary Structure
MLIKGNILNVFTDEIYPGEIKIEHGIIESIKEVNADFNDIIVPGFIDAHIHIESSMLTPS
CEEECCEEEEEECCCCCCEEEECHHHHHHHHHHCCCCCCEEECCEEEEEEEEECCCCCHH
RFAEIALRHGTTSVIADPHEIANVMGMDGIDYMIDDAKKTPLKYYFTAPSCVPATKFEKS
HHHHHHHHCCCCEEEECHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCC
GATISPNIIDNLLSRPEFVALGEVMDYNAVISNEKSILEKIKIAKKYHKPIDGHAPLLSG
CCEECHHHHHHHHCCCCEEEECCHHCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
KNLQKYVKHGVITDHESTTKKEVAEKKRMGMKIMIREGSESKMLEKLIYSNCDFIVSDDL
CCHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEEECCC
KPEDLINGHLDKCLRKAVDYGMDPYEAIKLVTINPAEHYNLNAGSISPGKSADLVFIDNL
CHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCHHHCCCCCCCCCCCCCCCEEEECCC
RDFTVKRVVINGNTIFKKQKLLFRANPRPIDTTLHVSLTKPEDFDLKAQNPAHKSATVNL
CCCEEEEEEECCCEEEEEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEE
INVSDNTIITKQSSAKLSIQKKTIIPSVFEDILKISVVDRYGGNTISNGFVKGFGIKNGA
EEECCCEEEEECCCCEEEEEHHHCCHHHHHHHHHEEEEECCCCCCCCCCCEEEECCCCCC
IASSVSHDSHNIIVVGTNSEYMSRATNHLIENKGGLAAISNQAKLDVTLPIAGLMSDKPA
EEECCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEHHCCCCCCC
KVVANNSAKLNELVSNMGCELSSPFTSLSFMALPVVPEVKMTTNGLFNVNTHQFIDIIKE
EEEECCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEECCCCEEECCHHHHHHHHHC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA